Dirk P Dittmer

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. pmc Recent cancer incidence trends in an observational clinical cohort of HIV-infected patients in the US, 2000 to 2011
    Elizabeth L Yanik
    Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, 715 Mary Ellen Jones Building, Chapel Hill, NC, USA
    Infect Agent Cancer 8:18. 2013
  2. pmc Relationship of immunologic response to antiretroviral therapy with non-AIDS defining cancer incidence
    Elizabeth L Yanik
    aUniversity of North Carolina, Chapel Hill, North Carolina bNorthwestern University, Chicago, Illinois cUniversity of Washington, Seattle, Washington dUniversity of Alabama, Birmingham, Alabama eJohns Hopkins University, Baltimore, Maryland fUniversity of California, San Diego gUniversity of California, San Francisco, California, USA
    AIDS 28:979-87. 2014
  3. pmc An important role for mitochondrial antiviral signaling protein in the Kaposi's sarcoma-associated herpesvirus life cycle
    John A West
    Lineberger Comprehensive Cancer Center, Program in Global Oncology, and Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    J Virol 88:5778-87. 2014
  4. pmc Latency locus complements MicroRNA 155 deficiency in vivo
    Sang Hoon Sin
    Department of Microbiology and Immunology, Program in Global Oncology, Lineberger Comprehensive Cancer Center, and Center for AIDS Research, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    J Virol 87:11908-11. 2013
  5. pmc Expression profile of microRNAs in Epstein-Barr virus-infected AGS gastric carcinoma cells
    Aron R Marquitz
    Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    J Virol 88:1389-93. 2014
  6. pmc Systemically circulating viral and tumor-derived microRNAs in KSHV-associated malignancies
    PAULINE E CHUGH
    Lineberger Comprehensive Cancer Center, Program in Global Oncology, Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
    PLoS Pathog 9:e1003484. 2013
  7. pmc Incidence and timing of cancer in HIV-infected individuals following initiation of combination antiretroviral therapy
    Elizabeth L Yanik
    Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27599, USA
    Clin Infect Dis 57:756-64. 2013
  8. pmc Maribavir inhibits Epstein-Barr virus transcription through the EBV protein kinase
    Christopher B Whitehurst
    Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    J Virol 87:5311-5. 2013
  9. pmc Kaposi sarcoma associated herpesvirus pathogenesis (KSHV)--an update
    Dirk P Dittmer
    Lineberger Comprehensive Cancer Center and Department of Microbiology and Immunology, Program in Global Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States
    Curr Opin Virol 3:238-44. 2013
  10. pmc Viral latency locus augments B-cell response in vivo to induce chronic marginal zone enlargement, plasma cell hyperplasia, and lymphoma
    Sang Hoon Sin
    Department of Microbiology and Immunology and Lineberger Comprehensive Cancer Center, Center for AIDS Research, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Blood 121:2952-63. 2013

Collaborators

Detail Information

Publications11

  1. pmc Recent cancer incidence trends in an observational clinical cohort of HIV-infected patients in the US, 2000 to 2011
    Elizabeth L Yanik
    Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, 715 Mary Ellen Jones Building, Chapel Hill, NC, USA
    Infect Agent Cancer 8:18. 2013
    ..We assessed changes in the distribution of cancer types and incidence trends among HIV-infected patients in North Carolina up until 2011...
  2. pmc Relationship of immunologic response to antiretroviral therapy with non-AIDS defining cancer incidence
    Elizabeth L Yanik
    aUniversity of North Carolina, Chapel Hill, North Carolina bNorthwestern University, Chicago, Illinois cUniversity of Washington, Seattle, Washington dUniversity of Alabama, Birmingham, Alabama eJohns Hopkins University, Baltimore, Maryland fUniversity of California, San Diego gUniversity of California, San Francisco, California, USA
    AIDS 28:979-87. 2014
    ..To estimate the association between immunologic response to antiretroviral therapy (ART) and non-AIDS defining cancer (NADC) incidence in HIV-infected patients...
  3. pmc An important role for mitochondrial antiviral signaling protein in the Kaposi's sarcoma-associated herpesvirus life cycle
    John A West
    Lineberger Comprehensive Cancer Center, Program in Global Oncology, and Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    J Virol 88:5778-87. 2014
    ..Finally, MAVS depletion in latent KSHV-infected B cells leads to increased viral gene transcription. Overall, this study suggests a role for MAVS and RIG-I signaling during different stages of the KSHV life cycle...
  4. pmc Latency locus complements MicroRNA 155 deficiency in vivo
    Sang Hoon Sin
    Department of Microbiology and Immunology, Program in Global Oncology, Lineberger Comprehensive Cancer Center, and Center for AIDS Research, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    J Virol 87:11908-11. 2013
    ..Germinal center (GC) formation was rescued in spleen, lymph node, and Peyer's patches. Immunoglobulin levels were restored. This demonstrates that KSHV can complement the normal, physiological function of miR-155. ..
  5. pmc Expression profile of microRNAs in Epstein-Barr virus-infected AGS gastric carcinoma cells
    Aron R Marquitz
    Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    J Virol 88:1389-93. 2014
    ..These changes likely reflect expression of the viral noncoding RNAs and not latent protein expression. ..
  6. pmc Systemically circulating viral and tumor-derived microRNAs in KSHV-associated malignancies
    PAULINE E CHUGH
    Lineberger Comprehensive Cancer Center, Program in Global Oncology, Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
    PLoS Pathog 9:e1003484. 2013
    ..These could represent candidate biomarkers of disease and may contribute to the paracrine phenotypes that are a characteristic of KS. ..
  7. pmc Incidence and timing of cancer in HIV-infected individuals following initiation of combination antiretroviral therapy
    Elizabeth L Yanik
    Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27599, USA
    Clin Infect Dis 57:756-64. 2013
    ..Cancer is an important cause of morbidity and mortality in individuals infected with human immunodeficiency virus (HIV), but patterns of cancer incidence after combination antiretroviral therapy (ART) initiation remain poorly characterized...
  8. pmc Maribavir inhibits Epstein-Barr virus transcription through the EBV protein kinase
    Christopher B Whitehurst
    Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    J Virol 87:5311-5. 2013
    ..MBV inhibits viral genome copy numbers and infectivity to levels similar to and exceeding levels produced by BGLF4 knockout virus...
  9. pmc Kaposi sarcoma associated herpesvirus pathogenesis (KSHV)--an update
    Dirk P Dittmer
    Lineberger Comprehensive Cancer Center and Department of Microbiology and Immunology, Program in Global Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States
    Curr Opin Virol 3:238-44. 2013
    ..Here we review the latest advances in our knowledge of KSHV pathogenesis. ..
  10. pmc Viral latency locus augments B-cell response in vivo to induce chronic marginal zone enlargement, plasma cell hyperplasia, and lymphoma
    Sang Hoon Sin
    Department of Microbiology and Immunology and Lineberger Comprehensive Cancer Center, Center for AIDS Research, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Blood 121:2952-63. 2013
    ....
  11. pmc Tousled-like kinases modulate reactivation of gammaherpesviruses from latency
    Patrick J Dillon
    Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Cell Host Microbe 13:204-14. 2013
    ..TLKs were also found to play a role in regulating reactivation from latency of another related oncogenic gammaherpesvirus, Epstein-Barr virus. Our results establish the TLKs as cellular repressors of gammaherpesvirus reactivation...