Research Topics
Species | Shou-Wei DingSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
RNA silencing: a conserved antiviral immunity of plants and animalsShou Wei Ding
Center for Plant Cell Biology, Department of Plant Pathology, Riverside, CA 92521, USA
Virus Res 102:109-15. 2004..Finally, we discuss evidence that suggests a natural antiviral role for RNA silencing in vertebrates as well as experimental approaches that may facilitate the identification of first mammalian viral suppressors of RNA silencing...
Antiviral immunity directed by small RNAsShou Wei Ding
Department of Plant Pathology and Microbiology, University of California, Riverside, CA 92521, USA
Cell 130:413-26. 2007..Meanwhile, viral mechanisms to suppress this small RNA-directed immunity by viruses are being elucidated, thereby illuminating an ongoing molecular arms race that likely impacts the evolution of both viral and host genomes...
RNA-based antiviral immunityShou Wei Ding
Department of Plant Pathology and Microbiology, and Institute for Integrative Genome Biology, University of California, Riverside, California 92521, USA
Nat Rev Immunol 10:632-44. 2010....
Virus-derived siRNAs and piRNAs in immunity and pathogenesisShou Wei Ding
Department of Plant Pathology and Microbiology, and Institute for Integrative Genome Biology, University of California, Riverside, CA 92521, United States
Curr Opin Virol 1:533-44. 2011..Here we review recent developments on the characterization and function of virus-derived siRNAs and piRNAs in eukaryotic hosts...
RNA-based immunity terminates viral infection in adult Drosophila in the absence of viral suppression of RNA interference: characterization of viral small interfering RNA populations in wild-type and mutant fliesYan Hong Han
Department of Plant Pathology and Microbiology and Institute for Integrative Genome Biology and Program for Cell, Molecular, and Developmental Biology, University of California, Riverside, CA 92521, USA
J Virol 85:13153-63. 2011..We propose that degradation of the asymmetrically produced viral positive-strand RNAs associated with abundant virus accumulation contributes to the positive-strand bias of viral small RNAs...
Mechanism of induction and suppression of antiviral immunity directed by virus-derived small RNAs in DrosophilaRoghiyh Aliyari
Department of Plant Pathology and Microbiology, Institute for Integrative Genome Biology, University of California, Riverside, Riverside, CA 92521, USA
Cell Host Microbe 4:387-97. 2008..Our findings, therefore, provide a model in which small RNA-directed viral immunity is induced during the initiation of viral progeny (+)RNA synthesis and suppressed by B2 inside the viral RNA replication complex...
RNA interference directs innate immunity against viruses in adult DrosophilaXiao Hong Wang
Graduate Program for Microbiology, University of California, Riverside, CA 92521, USA
Science 312:452-4. 2006..These findings establish a Drosophila model for studying the innate immunity against viruses in animals...
Suppression of antiviral silencing by cucumber mosaic virus 2b protein in Arabidopsis is associated with drastically reduced accumulation of three classes of viral small interfering RNAsJuan A Diaz-Pendon
Center for Plant Cell Biology, Department of Plant Pathology and Microbiology, University of California, Riverside, CA 92521, USA
Plant Cell 19:2053-63. 2007....
Antiviral silencing in animalsHong Wei Li
Center for Plant Cell Biology, Institute for Integrative Genome Biology, Department of Plant Pathology, University of California, Riverside, CA 92521, USA
FEBS Lett 579:5965-73. 2005..We propose that herpes viral miRNAs may act as specificity factors to initiate heterochromatin assembly of the latent viral DNA genome in the nucleus...
Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencingWan Xiang Li
Departments of Plant Pathology and Entomology and Microbiology Program, University of California, Riverside, CA 92521, USA
Proc Natl Acad Sci U S A 101:1350-5. 2004..These findings provide evidence that mammalian virus proteins can inhibit RNA silencing, implicating this mechanism as a nucleic acid-based antiviral immunity in mammalian cells...
Virus counterdefense: diverse strategies for evading the RNA-silencing immunityFeng Li
Graduate Program for Microbiology, Institute for Integrative Genome Biology, University of California, Riverside, California 92521, USA
Annu Rev Microbiol 60:503-31. 2006..We propose that VSR families are evolved independently as a viral adaptation to immunity. Unresolved issues on the role of RNA silencing in virus-host interactions are highlighted...
Direct and indirect roles of viral suppressors of RNA silencing in pathogenesisJuan A Diaz-Pendon
Center for Plant Cell Biology, Department of Plant Pathology and Microbiology, University of California, Riverside, California 92521, USA
Annu Rev Phytopathol 46:303-26. 2008..We also highlight many of the key questions still to be addressed on the role of viral suppression of antiviral silencing in plant infection...
Three distinct suppressors of RNA silencing encoded by a 20-kb viral RNA genomeRui Lu
Center for Plant Cell Biology, Institute for Integrative Genome Biology, and Department of Plant Pathology, University of California, Riverside, CA 92521, USA
Proc Natl Acad Sci U S A 101:15742-7. 2004....
Hibiscus chlorotic ringspot virus coat protein inhibits trans-acting small interfering RNA biogenesis in ArabidopsisChunying Meng
Department of Biological Sciences, 14 Science Drive 4, National University of Singapore, 117545 Singapore
J Gen Virol 89:2349-58. 2008..The reduced accumulation of ta-siRNA might result from the interference of HCRSV CP with Dicer-like protein(s), responsible for the generation of dsRNA in ta-siRNA biogenesis...
The p23 protein of hibiscus chlorotic ringspot virus is indispensable for host-specific replicationXiao-Zhen Liang
Department of Biological Sciences. Institute of Molecular Agrobiology, The National University of Singapore, Singapore 117604, Republic of Singapore
J Virol 76:12312-9. 2002..In addition, we show that p23 does not bind nucleic acids in vitro and does not act as a suppressor of posttranscriptional gene silencing in transgenic tobacco carrying a green fluorescent protein...
