Joel Dimsdale

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Mood Predicts Response to Placebo CPAP
    Carl J Stepnowsky
    Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA Health Services Research and Development Service, Veterans Affairs San Diego Healthcare System, San Diego, CA 92161, USA
    Sleep Disord 2012:404196. 2012
  2. doi request reprint Somatic symptom disorder: an important change in DSM
    Joel E Dimsdale
    Department of Psychiatry, University of California, San Diego, USA
    J Psychosom Res 75:223-8. 2013
  3. ncbi request reprint Taking fatigue seriously: I. Variations in fatigue sampled repeatedly in healthy controls
    J E Dimsdale
    Department of Psychiatry, University of California, San Diego 92093 0804, USA
    J Med Eng Technol 27:218-22. 2003
  4. ncbi request reprint Taking fatigue seriously, II: variability in fatigue levels in cancer patients
    Joel E Dimsdale
    Dept of Psychiatry, Univ of California, San Diego, CA 92093 0804, USA
    Psychosomatics 48:247-52. 2007
  5. ncbi request reprint The effect of opioids on sleep architecture
    Joel E Dimsdale
    Department of Psychiatry, University of California, San Diego, USA
    J Clin Sleep Med 3:33-6. 2007
  6. pmc A biological substrate for somatoform disorders: importance of pathophysiology
    Joel E Dimsdale
    Department of Psychiatry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0804, USA
    Psychosom Med 69:850-4. 2007
  7. pmc Psychological stress and cardiovascular disease
    Joel E Dimsdale
    University of California, San Diego, La Jolla, California 92093, USA
    J Am Coll Cardiol 51:1237-46. 2008
  8. ncbi request reprint Effect of continuous positive airway pressure on blood pressure : a placebo trial
    J E Dimsdale
    Departments of Psychiatry, University of California at San Diego, La Jolla, CA 92093 0804, USA
    Hypertension 35:144-7. 2000
  9. pmc Sleep in Othello
    Joel E Dimsdale
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093 0804, USA
    J Clin Sleep Med 5:280-1. 2009
  10. pmc Beyond the global assessment of functioning: learning from Virginia Apgar
    Joel E Dimsdale
    correspondence and M D, Dept of Psychiatry, Univ of California, San Diego, 9500 Gilman Dr, La Jolla, CA 92093 0804, USA
    Psychosomatics 51:515-9. 2010

Research Grants

  1. STRESS, BLOOD PRESSURE AND ETHNICITY
    Joel E Dimsdale; Fiscal Year: 2010
  2. STRESS PHYSIOLOGY, DIETARY SALT, AND HYPERTENSION
    Joel Dimsdale; Fiscal Year: 1992
  3. SLEEP APNEA & HYPERTENSION: ROLE OF S. NERVOUS SYSTEM
    Joel Dimsdale; Fiscal Year: 1991
  4. Sleep Apnea and Hypertension: Role of SNS
    Joel Dimsdale; Fiscal Year: 2005
  5. SLEEP APNEA & HYPERTENSION--ROLE OF SYMP NERVOUS SYSTEM
    Joel Dimsdale; Fiscal Year: 2000
  6. STRESS, BLOOD PRESSURE AND ETHNICITY
    Joel Dimsdale; Fiscal Year: 2000
  7. STRESS, BLOOD PRESSURE AND ETHNICITY
    Joel Dimsdale; Fiscal Year: 2001
  8. Sleep Apnea and Hypertension: Role of SNS
    Joel Dimsdale; Fiscal Year: 2004
  9. STRESS, BLOOD PRESSURE AND ETHNICITY
    Joel Dimsdale; Fiscal Year: 2002
  10. Sleep Apnea and Hypertension: Role of SNS
    Joel Dimsdale; Fiscal Year: 2006

Detail Information

Publications94

  1. pmc Mood Predicts Response to Placebo CPAP
    Carl J Stepnowsky
    Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA Health Services Research and Development Service, Veterans Affairs San Diego Healthcare System, San Diego, CA 92161, USA
    Sleep Disord 2012:404196. 2012
    ..These findings underscore the importance of placebo-controlled studies of CPAP treatment. Whereas such trials are routinely included in drug trials, this paper argues for their importance even in mechanical-oriented sleep interventions...
  2. doi request reprint Somatic symptom disorder: an important change in DSM
    Joel E Dimsdale
    Department of Psychiatry, University of California, San Diego, USA
    J Psychosom Res 75:223-8. 2013
    ..Data are presented concerning reliability, validity, and prevalence of SSD, as well as tasks for future research, education, and clinical practice. ..
  3. ncbi request reprint Taking fatigue seriously: I. Variations in fatigue sampled repeatedly in healthy controls
    J E Dimsdale
    Department of Psychiatry, University of California, San Diego 92093 0804, USA
    J Med Eng Technol 27:218-22. 2003
    ....
  4. ncbi request reprint Taking fatigue seriously, II: variability in fatigue levels in cancer patients
    Joel E Dimsdale
    Dept of Psychiatry, Univ of California, San Diego, CA 92093 0804, USA
    Psychosomatics 48:247-52. 2007
    ..Multiple ratings of fatigue within short periods of time can be obtained and reveal that fatigue levels are quite variable, even within an individual. Cancer patients experience their fatigue as "moderate to extreme" 33% of the time...
  5. ncbi request reprint The effect of opioids on sleep architecture
    Joel E Dimsdale
    Department of Psychiatry, University of California, San Diego, USA
    J Clin Sleep Med 3:33-6. 2007
    ..This study examined whether commonly used opioid medications have an adverse effect on sleep architecture in healthy adults...
  6. pmc A biological substrate for somatoform disorders: importance of pathophysiology
    Joel E Dimsdale
    Department of Psychiatry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0804, USA
    Psychosom Med 69:850-4. 2007
    ..Studies on communication pathways from the immune system to the brain provide exciting new information on the pathophysiology of inflammation-associated symptoms...
  7. pmc Psychological stress and cardiovascular disease
    Joel E Dimsdale
    University of California, San Diego, La Jolla, California 92093, USA
    J Am Coll Cardiol 51:1237-46. 2008
    ..Numerous approaches are available for stress management that can decrease patients' suffering and enhance their quality of life...
  8. ncbi request reprint Effect of continuous positive airway pressure on blood pressure : a placebo trial
    J E Dimsdale
    Departments of Psychiatry, University of California at San Diego, La Jolla, CA 92093 0804, USA
    Hypertension 35:144-7. 2000
    ..However, the decrease in daytime blood pressure may reflect a nonspecific response (ie, placebo), since both the active treatment group and the placebo treatment group developed comparable decreases in blood pressure...
  9. pmc Sleep in Othello
    Joel E Dimsdale
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093 0804, USA
    J Clin Sleep Med 5:280-1. 2009
    ..This paper examines sleep themes in Shakespeare's play Othello. The play indicates Shakespeare's astute eye for sleep deprivation, sexual parasomnias, and effects of stress and drugs on sleep...
  10. pmc Beyond the global assessment of functioning: learning from Virginia Apgar
    Joel E Dimsdale
    correspondence and M D, Dept of Psychiatry, Univ of California, San Diego, 9500 Gilman Dr, La Jolla, CA 92093 0804, USA
    Psychosomatics 51:515-9. 2010
    ..The Global Assessment of Functioning (GAF) scale is widely used in psychiatry, yet it has certain drawbacks...
  11. ncbi request reprint Reliability of nocturnal blood pressure dipping
    J E Dimsdale
    Department of Psychiatry, University of California, San Diego, USA
    Blood Press Monit 5:217-21. 2000
    ..Increasing evidence documents the fact that individuals whose blood pressure drops or 'dips' relatively little at night have a higher risk of numerous cardiovascular illnesses...
  12. pmc Effect of eszopiclone on sleep, fatigue, and pain in patients with mucositis associated with hematologic malignancies
    Joel E Dimsdale
    Department of Psychiatry, University of California, San Diego, San Diego, USA
    Support Care Cancer 19:2015-20. 2011
    ..This study examined whether treatment with the sedative hypnotic eszopiclone could improve self-reports of sleep, fatigue, and pain as well as decrease opioid self-administered via PCA...
  13. ncbi request reprint An unanticipated effect of meditation on cardiovascular pharmacology and physiology
    Joel E Dimsdale
    Department of Psychiatry, University of California, San Diego, La Jolla, California 92093, USA
    Am J Cardiol 90:908-9. 2002
  14. ncbi request reprint Stalked by the past: the influence of ethnicity on health
    J E Dimsdale
    Department of Psychiatry, University of California, San Diego 92093 0804, USA
    Psychosom Med 62:161-70. 2000
    ..The author's clinical research studies on this topic for the last 20 years are reviewed in this article...
  15. doi request reprint What do physicians think of somatoform disorders?
    Joel Dimsdale
    Dept of Psychiatry, University of California, San Diego, CA 92093 0804, USA
    Psychosomatics 52:154-9. 2011
    ..The aim of this study was to elicit the views of physicians who see these patients...
  16. pmc Number of lapses during the psychomotor vigilance task as an objective measure of fatigue
    In Soo Lee
    Department of Psychiatry, University of California San Diego, San Diego, CA 92103 0804, USA
    J Clin Sleep Med 6:163-8. 2010
    ..We also examined if the PVT/fatigue relationship could be influenced by depressive symptoms...
  17. pmc Overnight changes of immune parameters and catecholamines are associated with mood and stress
    Winfried Rief
    Department of Psychiatry, University of California, San Diego, San Diego, California, USA
    Psychosom Med 72:755-62. 2010
    ..To test the hypothesis that a nocturnal decrease of secretion of inflammation markers and catecholamines would be associated with mood and stress variables even after controlling for objective sleep variables...
  18. ncbi request reprint Association of negative life event stress with coagulation activity in elderly Alzheimer caregivers
    Roland von Kanel
    Department of Psychiatry, University of California, San Diego, La Jolla 92093 0680, USA
    Psychosom Med 65:145-50. 2003
    ..We wondered whether negative life stress might affect hemostatic function in caregivers...
  19. ncbi request reprint Sleep in spousal caregivers of people with Alzheimer's disease
    Christine L McKibbin
    Department of Psychiatry, University of California San Diego, CA, USA
    Sleep 28:1245-50. 2005
    ..This study examined differences in objective and subjective measures of sleep between caregivers and noncaregivers...
  20. ncbi request reprint Independent contribution of psychological factors to fibrin turnover in subjects with sleep apnoea and/or systemic hypertension
    Roland von Kanel
    Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0804, USA
    Clin Sci (Lond) 103:331-7. 2002
    ..These results may provide a rationale for linking behavioural aspects with cardiovascular events...
  21. ncbi request reprint Association between polysomnographic measures of disrupted sleep and prothrombotic factors
    Roland von Kanel
    Department of Psychiatry, University of California San Diego, 9500 Gilman Dr, La Jolla, CA 92093 0804, USA
    Chest 131:733-9. 2007
    ..We hypothesized that disrupted sleep as verified by polysomnography is associated with increased levels of prothrombotic hemostasis factors previously shown to predict CAD risk...
  22. ncbi request reprint Coping processes and hemostatic reactivity to acute stress in dementia caregivers
    Kirstin Aschbacher
    Department of Psychiatry, School of Medicine, University of California, San Diego, California, USA
    Psychosom Med 67:964-71. 2005
    ..A hypercoagulable stress response might contribute to the increased cardiovascular risk in Alzheimer's caregivers...
  23. ncbi request reprint Dementia severity of the care receiver predicts procoagulant response in Alzheimer caregivers
    Kirstin Aschbacher
    Department of Psychiatry, School of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Am J Geriatr Psychiatry 14:694-703. 2006
    ..Research has demonstrated that spousal dementia caregivers have elevated levels of D-dimer relative to their non-caregiving peers...
  24. pmc Personal mastery is associated with reduced sympathetic arousal in stressed Alzheimer caregivers
    Susan K Roepke
    Department of Psychiatry, University of California at San Diego, La Jolla, CA 92093 0680, USA
    Am J Geriatr Psychiatry 16:310-7. 2008
    ..This study examines the relationship between mastery and sympathetic arousal in elderly caregivers, as measured by norepinephrine (NE) reactivity to an acute psychological stressor...
  25. ncbi request reprint Assessing the trade-offs between crossover and parallel group designs in sleep research
    Charles C Berry
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA, USA
    J Sleep Res 15:348-57. 2006
    ..Despite the operational complexity of a crossover design, the statistical efficiency of this approach makes it a preferable approach for designing intervention studies in sleep research...
  26. ncbi request reprint Effects of nonspecific beta-adrenergic stimulation and blockade on blood coagulation in hypertension
    Roland von Kanel
    Department of Psychiatry, University of California, San Diego, California 92093, USA
    J Appl Physiol 94:1455-9. 2003
    ..However, beta-adrenergic stimulation alone may not be sufficient to trigger fibrin formation in vivo...
  27. ncbi request reprint Effects of depressive symptoms and anxiety on hemostatic responses to acute mental stress and recovery in the elderly
    Roland von Kanel
    Department of Psychiatry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0680, USA
    Psychiatry Res 126:253-64. 2004
    ..The independent association of anxiety symptoms with resting and stress-induced fibrin formation (D-dimer) may be a mechanism linking mood with cardiovascular disease risk in the elderly...
  28. pmc Effects of depressive and anxious symptoms on norepinephrine and platelet P-selectin responses to acute psychological stress among elderly caregivers
    Kirstin Aschbacher
    Department of Psychiatry, University of California, San Diego, 9500 Gilman Drive, La Jolla CA 92093 0680, USA
    Brain Behav Immun 22:493-502. 2008
    ....
  29. ncbi request reprint Health-related quality of life in women previously treated for early-stage breast cancer
    Wayne A Bardwell
    University of California, San Diego, Comprehensive Cancer Center, La Jolla 92093 0645, USA
    Psychooncology 13:595-604. 2004
    ..Interventions targeting psychosocial symptoms, weight reduction, physical activity, sleep hygiene, and pain could result in improved HRQOL in these women...
  30. ncbi request reprint Acute procoagulant stress response as a dynamic measure of allostatic load in Alzheimer caregivers
    Roland von Kanel
    Department of Psychiatry, University of California San Diego, La Jolla 92093 0680, USA
    Ann Behav Med 26:42-8. 2003
    ..The acute procoagulant stress response might constitute a dynamic mediator of allostatic load in Alzheimer caregivers...
  31. ncbi request reprint Relation of nocturnal blood pressure dipping to cellular adhesion, inflammation and hemostasis
    Roland von Kanel
    Department of Psychiatry, University of California San Diego, California 92093 0804, USA
    J Hypertens 22:2087-93. 2004
    ..The pathogenetic mechanisms of this relationship have not been elucidated. We investigated whether non-dipping would relate to procoagulant and proinflammatory activity...
  32. pmc Macrophage migratory inhibitory factor (MIF) may be a key factor in inflammation in obstructive sleep apnea
    Kate M Edwards
    Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Sleep 34:161-3. 2011
    ....
  33. pmc Fatigue, sleep, and circadian rhythms prior to chemotherapy for breast cancer
    Sonia Ancoli-Israel
    Department of Psychiatry, University of California, San Diego, CA 92161, USA
    Support Care Cancer 14:201-9. 2006
    ..However, most of the previous research examined women either during or after chemotherapy. This study examined sleep, fatigue, and circadian rhythms in women with breast cancer before the start of chemotherapy...
  34. ncbi request reprint The effect of race and sleep-disordered breathing on nocturnal BP "dipping": analysis in an older population
    Sonia Ancoli-Israel
    Department of Psychiatry, University of California, San Diego, CA, USA
    Chest 122:1148-55. 2002
    ..This study examined whether nondipping in older African Americans and older white subjects is related to the presence of sleep-disordered breathing (SDB) and hypertension...
  35. ncbi request reprint In-home respite intervention reduces plasma epinephrine in stressed Alzheimer caregivers
    Igor Grant
    Department of Psychiatry 0680, University of California, San Diego, La Jolla 92093 0680, USA
    Am J Geriatr Psychiatry 11:62-72. 2003
    ..Authors tested the efficacy of an in-home respite intervention to reduce peripheral markers of SAM activation and psychological distress in spousal caregivers of patients with Alzheimer disease...
  36. ncbi request reprint Differential immune cell chemotaxis responses to acute psychological stress in Alzheimer caregivers compared to non-caregiver controls
    Laura Redwine
    Department of Psychiatry, University of California, San Diego, USA
    Psychosom Med 66:770-5. 2004
    ..Correlations between immune cell chemotaxis and epinephrine and norepinephrine levels were also examined...
  37. ncbi request reprint Physical activity and perception of energy and fatigue in obstructive sleep apnea
    Suzi Hong
    Department of Psychiatry, University of California, San Diego, CA 92103 0804, USA
    Med Sci Sports Exerc 35:1088-92. 2003
    ..This study was designed to examine the relationship between apnea severity, physical activity level, and psychological well being in patients with obstructive sleep apnea (OSA)...
  38. pmc The relationship between fatigue and cardiac functioning
    Richard Nelesen
    Department of Psychiatry, University of California San Diego, La Jolla, CA 92093 0804, USA
    Arch Intern Med 168:943-9. 2008
    ..This study examined the relationship between self-reported fatigue and hemodynamic functioning at rest and in response to a public speaking stressor in healthy individuals...
  39. pmc Pre-treatment symptom cluster in breast cancer patients is associated with worse sleep, fatigue and depression during chemotherapy
    Lianqi Liu
    Department of Psychiatry, University of California, San Diego, CA 92161, USA
    Psychooncology 18:187-94. 2009
    ..e. sleep disturbances, fatigue and depression) into one symptom cluster, to explore the associations between pre-treatment cluster categories and longitudinal profiles of these same symptoms during chemotherapy...
  40. ncbi request reprint Combination of caregiving stress and hormone replacement therapy is associated with prolonged platelet activation to acute stress among postmenopausal women
    Kirstin Aschbacher
    Department of Psychiatry, School of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093 0680, USA
    Psychosom Med 69:910-7. 2007
    ..Both HRT and the chronic stress of caregiving have been associated with increased cardiovascular risk, potentially through a mechanism of platelet hyperactivity...
  41. pmc Persistent versus transient depressive symptoms in relation to platelet hyperactivation: a longitudinal analysis of dementia caregivers
    Kirstin Aschbacher
    Department of Psychiatry, University of California, San Diego, USA
    J Affect Disord 116:80-7. 2009
    ..The primary objective was to investigate whether persistent depressive symptoms would relate to elevated platelet activation in response to acute psychological stress over a three-year period...
  42. pmc Neuropsychological effects of 2-week continuous positive airway pressure treatment and supplemental oxygen in patients with obstructive sleep apnea: a randomized placebo-controlled study
    Weonjeong Lim
    Department ofPsychiatry, University of California San Diego, La Jolla, CA 92093 0804, USA
    J Clin Sleep Med 3:380-6. 2007
    ....
  43. ncbi request reprint Temporal stability of acute stress-induced changes in leukocyte subsets and cellular adhesion molecules in older adults
    Karen A Adler
    Department of Psychiatry, University of California San Diego, La Jolla, CA 92093, USA
    Brain Behav Immun 16:262-74. 2002
    ..The level of temporal stability achieved is comparable to that seen previously in younger adults, indicating that acute psychosocial stress produces reliable changes in circulating leukocytes and cell adhesion molecules in older adults...
  44. ncbi request reprint Psychologic correlates of compliance with continuous positive airway pressure
    Carl J Stepnowsky
    Department of Psychiatry, University of California, San Diego 92093 0804, USA
    Sleep 25:758-62. 2002
    ..To explore the relationship between psychologic variables measured prior to continuous positive airway pressure (CPAP) treatment and subsequent CPAP compliance...
  45. ncbi request reprint Ethnicity, perceived discrimination, and vascular reactivity to phenylephrine
    KaMala S Thomas
    San Diego State University and University of California, San Diego Joint Doctoral Program in Clinical Psychology, San Diego, California, USA
    Psychosom Med 68:692-7. 2006
    ..This study examined relationships among ethnicity, perceived discrimination, and vascular reactivity to phenylephrine (PE)...
  46. ncbi request reprint Conceptual foundations of the UCSD Statin Study: a randomized controlled trial assessing the impact of statins on cognition, behavior, and biochemistry
    Beatrice Alexandra Golomb
    Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA
    Arch Intern Med 164:153-62. 2004
    ..However, there has been persistent controversy regarding possible favorable or adverse effects of statins or of cholesterol reduction on cognition, mood, and behavior (including aggressive or violent behavior)...
  47. ncbi request reprint Interactive effects of common beta2-adrenoceptor haplotypes and age on susceptibility to hypertension and receptor function
    Xuping Bao
    Department of Medicine, University of California, San Diego, CA, USA
    Hypertension 46:301-7. 2005
    ..05) and decreased heart rate (7%; P<0.001). Our study suggests that age is an important modifier for the effects of ADRB2 polymorphisms on ADRB2 function and the development of hypertension...
  48. ncbi request reprint Effect of beta2-adrenergic receptor functioning and increased norepinephrine on the hypercoagulable state with mental stress
    Roland von Kanel
    Department of Psychiatry, University of California, San Diego, Calif 92093 0804, USA
    Am Heart J 144:68-72. 2002
    ....
  49. pmc A comparison of pharmacologic and spontaneous baroreflex methods in aging and hypertension
    Milos Milic
    Department of Medicine, University of California at San Diego, San Diego, California 92103 8341, USA
    J Hypertens 27:1243-51. 2009
    ..We also examined whether heart rate variability (HRV) provides as much information as does BRS...
  50. ncbi request reprint Point subtraction aggression paradigm: validity of a brief schedule of use
    Beatrice A Golomb
    Department of Medicine, School of Medicine, University of California, San Diego, La Jolla, CA 92093 0995, USA
    Violence Vict 22:95-103. 2007
    ..The PSAP-FS had satisfactory validity properties for use where group-level data are of interest...
  51. pmc Carotid plaque in Alzheimer caregivers and the role of sympathoadrenal arousal
    Susan K Roepke
    San Diego State University University of California, San Diego, USA
    Psychosom Med 73:206-13. 2011
    ..Providing care for a spouse with Alzheimer's disease has been associated with an increased risk of coronary heart disease, potentially due to the impact of caregiving stress on the atherosclerotic disease process...
  52. ncbi request reprint Use of herbal medications among 200 psychiatric outpatients: prevalence, patterns of use, and potential dangers
    Scott C Matthews
    Department of Psychiatry, University of California, San Diego, San Diego, CA, USA
    Gen Hosp Psychiatry 25:24-6. 2003
    ..These data are consistent with reports from other patient populations. It is important for psychiatrists to ask all patients about their use of herbs and provide education about potentially dangerous drug-herb interactions...
  53. ncbi request reprint Use of radial arterial tonometric continuous blood pressure measurement in cardiovascular reactivity studies
    Richard A Nelesen
    Department of Psychiatry, University of California, San Diego, La Jolla, 92093, USA
    Blood Press Monit 7:259-63. 2002
    ..Radial tonometry is a new methodology for measuring non-invasive beat-to-beat blood pressure. This technique has been evaluated for other applications, but its use in cardiovascular reactivity testing has not yet been reported...
  54. pmc Adverse impact of mood on flow-mediated dilation
    Denise C Cooper
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093 0804, USA
    Psychosom Med 72:122-7. 2010
    ..Substantial literature indicates that negative mood is linked to cardiovascular disease (CVD). However, the mechanisms underlying this relationship are not well defined. CVD is often preceded by dysfunction of the endothelium...
  55. doi request reprint Sleep disruption in cystic fibrosis
    Herbert J Yue
    Department of Medicine, University of California, San Diego School of Medicine, La Jolla, CA, USA
    Med Hypotheses 71:886-8. 2008
    ..Further objective studies are needed to identify other contributors to sleep fragmentation and to evaluate outcomes with nocturnal supportive ventilation...
  56. ncbi request reprint Peripheral blood mononuclear cell CD62L and CD11a expression and soluble interstitial cell adhesion molecule-1 levels following infused isoproterenol in hypertension
    Paul J Mills
    Department of Psychiatry, University of California, San Diego, La Jolla, California, USA
    J Hypertens 20:311-6. 2002
    ....
  57. pmc The roles of TNF-alpha and the soluble TNF receptor I on sleep architecture in OSA
    Herbert J Yue
    Department of Medicine, University of California, San Diego School of Medicine, La Jolla, CA, USA
    Sleep Breath 13:263-9. 2009
    ..We hypothesized that the TNF receptor might play an important role in the inflammation as well as sleep architecture changes in patients with OSA...
  58. pmc Arousal frequency is associated with increased fatigue in obstructive sleep apnea
    Herbert J Yue
    Department of Medicine, University of California, San Diego School of Medicine, La Jolla, USA
    Sleep Breath 13:331-9. 2009
    ..We hypothesized that arousal frequency and changes in sleep architecture contribute to the fatigue experienced by patients with OSA...
  59. doi request reprint Racial differences in the impact of social support on nocturnal blood pressure
    Denise C Cooper
    Department of Psychiatry, University of California San Diego, 9500 Gilman Dr, 0804, La Jolla, CA 92093 0804, USA
    Psychosom Med 71:524-31. 2009
    ..To investigate whether black and white adults benefit similarly from perceived social support in relation to blood pressure (BP) dipping during sleep...
  60. pmc The effects of ethnic discrimination and socioeconomic status on endothelin-1 among blacks and whites
    Denise C Cooper
    Department of Psychiatry, University of California, San Diego, California, USA
    Am J Hypertens 22:698-704. 2009
    ..Stress is associated with increased endothelin-1 (ET-1). This study examined the relationship of ET-1 to socioeconomic status (SES) and to perceived ethnic discrimination among black (n = 51) and white (n = 65) adults (mean age 36.5)...
  61. pmc Everyday discrimination and nocturnal blood pressure dipping in black and white americans
    Lianne Tomfohr
    Department of Psychology, University of California, San Diego, 9500 Gilman Drive, Mail Code 0804, La Jolla, CA 92093 0804, USA
    Psychosom Med 72:266-72. 2010
    ..Attenuated nocturnal BP dipping is closely linked to cardiovascular morbidity and mortality. Self-reported experiences of everyday discrimination have also been associated with negative cardiovascular health outcomes...
  62. pmc Diurnal variability of C-reactive protein in obstructive sleep apnea
    Paul J Mills
    Department of Psychiatry, University of California, San Diego, La Jolla, 92093 0804, USA
    Sleep Breath 13:415-20. 2009
    ..The objective of this study is to examine the diurnal variability of C-reactive protein (CRP) in obstructive sleep apnea (OSA)...
  63. ncbi request reprint Ethnicity, social class and hostility: effects on in vivo beta-adrenergic receptor responsiveness
    Shamini Jain
    Department of Psychiatry, University of California, San Diego, CA, USA
    Biol Psychol 65:89-100. 2004
    ..Thus, decreased beta-adrenergic receptor responsiveness in African-Americans does not appear to be due to differences in current social class, age, or smoking status, nor to higher reports of hostility...
  64. ncbi request reprint Correlates of physical activity level in breast cancer survivors participating in the Women's Healthy Eating and Living (WHEL) Study
    Suzi Hong
    Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
    Breast Cancer Res Treat 101:225-32. 2007
    ..The purpose of this study was to examine factors that are associated with physical activity or inactivity among breast cancer survivors...
  65. ncbi request reprint Sleep disturbance, norepinephrine, and D-dimer are all related in elderly caregivers of people with Alzheimer disease
    Brent T Mausbach
    Department of Psychiatry, University of California, San Diego, CA 92093 0682, USA
    Sleep 29:1347-52. 2006
    ..In this study, we examined if sleep disturbance of elderly caregivers was associated with physiologic markers of cardiovascular risk, including plasma norepinephrine, epinephrine, and the hemostasis marker D-dimer...
  66. ncbi request reprint Prediction of continuous positive airway pressure in obstructive sleep apnea
    Jose S Loredo
    Department of Medicine, University of California, San Diego, CA 92103 0804, USA
    Sleep Breath 11:45-51. 2007
    ....
  67. ncbi request reprint Autonomic responses to psychological stress: the influence of menopausal status
    Noha H Farag
    Department of Psychiatry, University of California, San Diego, CA 92103 0804, USA
    Ann Behav Med 26:134-8. 2003
    ..Postmenopausal women have greater sympathetic and less parasympathetic activity than premenopausal women, which may account for their increased risk of coronary artery disease...
  68. ncbi request reprint The association of social status and blood pressure with markers of vascular inflammation
    Suzi Hong
    Department of Psychiatry, University of California, San Diego, San Diego, California, USA
    Psychosom Med 68:517-23. 2006
    ..We examined the associations among BP, social status, and sICAM-1 and ET-1 levels in 121 European American and African American men and women...
  69. ncbi request reprint Vulnerable caregivers of Alzheimer disease patients have a deficit in beta 2-adrenergic receptor sensitivity and density
    Paul J Mills
    Department of Psychiatry, University of California San Diego, 92103 0804, USA
    Am J Geriatr Psychiatry 12:281-6. 2004
    ..The authors examined the effects of being a spousal caregiver of a patient with Alzheimer disease (AD) on the lymphocyte beta(2)-adrenergic receptor...
  70. ncbi request reprint Depressive symptoms predict norepinephrine response to a psychological stressor task in Alzheimer's caregivers
    Brent T Mausbach
    Department of Psychiatry, University of California at San Diego, La Jolla, CA 92093 0680, USA
    Psychosom Med 67:638-42. 2005
    ..The current study examined the relations between the level of depressive symptoms in spousal caregivers and the physiological response to a psychological stress task...
  71. ncbi request reprint The relationship between fatigue and quality of life and inflammation during anthracycline-based chemotherapy in breast cancer
    Paul J Mills
    Department of Psychiatry, University of California, San Diego UCSD, Medical Center, 200 West Arbor Drive, San Diego, CA 92103 0804, USA
    Biol Psychol 69:85-96. 2005
    ..001). The findings contribute to the literature by showing that both pre-chemotherapy and chemotherapy-induced changes in inflammation are related to changes in fatigue and quality of life in response to chemotherapy...
  72. ncbi request reprint Job strain, ethnicity, and sympathetic nervous system activity
    KaMala S Thomas
    San Diego State University, CA, USA
    Hypertension 44:891-6. 2004
    ..These findings suggest possible mechanisms by which job strain may be associated with cardiovascular disease...
  73. ncbi request reprint Sleep quality and blood pressure dipping in normal adults
    Jose S Loredo
    Department of Medicine, University of California, San Diego, 92103 0804, USA
    Sleep 27:1097-103. 2004
    ..To investigate the relationship between sleep quality and nocturnal blood pressure dipping in normal subjects. We hypothesized that sleep quality correlates with dipping...
  74. ncbi request reprint Effect of ethnicity on sleep: complexities for epidemiologic research
    Carl J Stepnowsky
    Department of Psychiatry, University of California, San Diego, La Jolla 92093 0804, USA
    Sleep 26:329-32. 2003
    ..The goal of this study was to examine whether there were ethnic differences in polysomnographically recorded sleep, either in the controlled laboratory environment or in the home setting...
  75. ncbi request reprint The effect of measurement unreliability on sleep and respiratory variables
    Carl J Stepnowsky
    Health Services Research and Development Service, Veterans Affairs San Diego Healthcare System, San Diego, CA 92161, USA
    Sleep 27:990-5. 2004
    ....
  76. ncbi request reprint Relationships between hostility, anger expression, and blood pressure dipping in an ethnically diverse sample
    KaMala S Thomas
    San Diego State University, San Diego Joint Doctoral, Program in Clinical Psychology, San Diego, CA, USA
    Psychosom Med 66:298-304. 2004
    ..The purpose of this study was to examine relationships between hostility, anger expression, and blood pressure (BP) dipping...
  77. pmc Inflammation and sleep in healthy individuals
    Paul J Mills
    Department of Psychiatry, University of California San Diego, School of Medicine, La Jolla, CA, USA
    Sleep 30:729-35. 2007
    ..Inflammation is relatively common in individuals with a sleep disorder and is associated with quality of sleep. The purpose of this study was to examine whether inflammation is associated with quality of sleep in healthy individuals...
  78. ncbi request reprint Effect of continuous positive airway pressure versus supplemental oxygen on sleep quality in obstructive sleep apnea: a placebo-CPAP-controlled study
    Jose S Loredo
    Department of Medicine, University of California, San Diego, CA 92103 0804, USA
    Sleep 29:564-71. 2006
    ..We investigated the short-term effectiveness of continuous positive airway pressure (CPAP) and oxygen in improving sleep quality in patients with obstructive sleep apnea (OSA)...
  79. ncbi request reprint Effects of perceived stress and uplifts on inflammation and coagulability
    Shamini Jain
    Joint Doctoral Program, Clinical Psychology, University of California San Diego San Diego State University, San Diego, California, USA
    Psychophysiology 44:154-60. 2007
    ....
  80. ncbi request reprint Association between sleep apnea severity and blood coagulability: Treatment effects of nasal continuous positive airway pressure
    Roland von Kanel
    Department of General Internal Medicine, University Hospital Bern, Bern, Switzerland
    Sleep Breath 10:139-46. 2006
    ..Apnea severity may be associated with impairment in the fibrinolytic capacity. To the extent that our sample size was limited, the observation that CPAP treatment led to a decrease in PAI-1 in OSA must be regarded as tentative...
  81. ncbi request reprint Poor sleep is associated with higher plasma proinflammatory cytokine interleukin-6 and procoagulant marker fibrin D-dimer in older caregivers of people with Alzheimer's disease
    Roland von Kanel
    Department of General Internal Medicine, University Hospital, Berne, Switzerland
    J Am Geriatr Soc 54:431-7. 2006
    ..To determine whether objective measures of sleep correlate with plasma levels of the proinflammatory cytokine interleukin (IL)-6 and the procoagulant marker fibrin D-dimer in caregivers of patients with dementia...
  82. ncbi request reprint Does obstructive sleep apnea increase hematocrit?
    Jong Bae Choi
    Department of Neuropsychiatry, Kyunggi Provincial Hospital for the Elderly, Kyunggi Do, South Korea
    Sleep Breath 10:155-60. 2006
    ..05). The severity of OSA is significantly associated with increased hematocrit, even after controlling for possible confounding variables. However, nocturnal hypoxemia in OSA does not usually lead to clinical polycythemia...
  83. ncbi request reprint Coping strategies, hostility, and depressive symptoms: a path model
    Wei Chung Mao
    Department of Psychiatry, Tri Service General Hospital, Taipei, Taiwan
    Int J Behav Med 10:331-42. 2003
    ..From a clinical perspective, knowing what coping strategies a person uses and how much anger they experience and express may be useful in guiding the management of depressive symptoms...
  84. ncbi request reprint The effect of psychosocial stress on sleep: a review of polysomnographic evidence
    Eui Joong Kim
    Department of Psychiatry, Eulji University School of Medicine, Daejeon, Korea
    Behav Sleep Med 5:256-78. 2007
    ..Without such fine-grained analyses, it is difficult to draw definitive conclusions about this important area...
  85. pmc Relationship between heart rate variability, interleukin-6, and soluble tissue factor in healthy subjects
    Roland von Kanel
    Department of General Internal Medicine, University Hospital Berne, Switzerland
    Brain Behav Immun 22:461-8. 2008
    ..Inflammation and related hypercoagulability might particularly contribute to atherothrombotic events in a setting of decreased HRV...
  86. ncbi request reprint Emotional expressiveness, hostility and blood pressure in a longitudinal cohort of Alzheimer caregivers
    William S Shaw
    Liberty Mutual Center for Disability Research, Hopkinton, MA, USA
    J Psychosom Res 54:293-302. 2003
    ..To assess the interactive effect of chronic stress and emotional expressiveness (EE) on blood pressure (BP) in older adults...
  87. ncbi request reprint The association between fatigue and inflammatory marker levels in cancer patients: a quantitative review
    Christian Schubert
    Clinical Department of Medical Psychology and Psychotherapy, Innsbruck Medical University, Innsbruck, Austria
    Brain Behav Immun 21:413-27. 2007
    ..Future studies examining the relationship between cancer related fatigue and inflammation would benefit from multiple rather than single blood sampling and from repeated daily ratings of the multidimensional nature of fatigue...
  88. doi request reprint Increased Framingham Coronary Heart Disease Risk Score in dementia caregivers relative to non-caregiving controls
    Roland von Kanel
    Department of General Internal Medicine, Division of Psychosomatic Medicine, University Hospital, Berne, Switzerland
    Gerontology 54:131-7. 2008
    ..Elderly individuals who provide care to a spouse suffering from dementia bear an increased risk of coronary heart disease (CHD)...
  89. ncbi request reprint Relation of autonomic activity to plasminogen activator inhibitor-1 plasma concentration and the role of body mass index
    Roland von Kanel
    Department of General Internal Medicine, University Hospital Berne, Switzerland
    Blood Coagul Fibrinolysis 18:353-9. 2007
    ..More apparent, higher BMI explained a significant proportion of the variance in the relationship between depressed sympathetic and parasympathetic activity and elevated plasma PAI-1 concentration...
  90. ncbi request reprint Effects of placement and bereavement on psychological well-being and cardiovascular risk in Alzheimer's caregivers: a longitudinal analysis
    Brent T Mausbach
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093 0680, USA
    J Psychosom Res 62:439-45. 2007
    ..We examined the impact of Alzheimer caregiver transitions (i.e., placement and bereavement) on psychological outcomes and on plasma D-dimer levels, an end product of the coagulation cascade associated with increased cardiovascular risk...
  91. ncbi request reprint Sleepiness in obstructive sleep apnea: a harbinger of impaired cardiac function?
    Jong Bae Choi
    Department of Neuropsychiatry, Kyunggi Provincial Hospital for the Elderly, Kyunggi Do, South Korea
    Sleep 29:1531-6. 2006
    ..The purpose of this study was to assess the relationship between degree of subjective daytime sleepiness and cardiac performance in patients with obstructive sleep apnea...
  92. pmc Mood states, sympathetic activity, and in vivo beta-adrenergic receptor function in a normal population
    Bum Hee Yu
    Department of Psychiatry, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Depress Anxiety 25:559-64. 2008
    ..These findings replicate previous reports that anxiety is related to decreased (i.e., desensitized) beta-adrenergic receptor sensitivity, even after controlling for age, gender, ethnicity, and body mass index...
  93. ncbi request reprint Effect of Alzheimer caregiving stress and age on frailty markers interleukin-6, C-reactive protein, and D-dimer
    Roland von Kanel
    Department of General Internal Medicine, Division of Psychosomatic Medicine, University Hospital, Switzerland
    J Gerontol A Biol Sci Med Sci 61:963-9. 2006
    ..We hypothesized that, compatible with premature frailty, chronic stress and age are related in predicting inflammation and coagulation activity in Alzheimer caregivers...
  94. ncbi request reprint Blood pressure variability in obstructive sleep apnea: role of sympathetic nervous activity and effect of continuous positive airway pressure
    Xuping Bao
    Department of Medicine, University of California San Diego, 92103 8341, USA
    Blood Press Monit 7:301-7. 2002
    ..We assessed the relationship between SNS activity and 24-h BP variability in patients with OSA, and the effect of continuous positive airway pressure (CPAP) on BP variability...

Research Grants47

  1. STRESS, BLOOD PRESSURE AND ETHNICITY
    Joel E Dimsdale; Fiscal Year: 2010
    ..The study scrutinizes sleep, inflammation, vasodilation, autonomic functioning, and baroreflex regulation. We hypothesize that adversity has a stronger impact on cardiovascular pathophysiology than does ethnicity. ..
  2. STRESS PHYSIOLOGY, DIETARY SALT, AND HYPERTENSION
    Joel Dimsdale; Fiscal Year: 1992
    ..This hormone has unusual characteristics which are apparently opposite those of norepinephrine in terms of sodium excretion and vasodilation...
  3. SLEEP APNEA & HYPERTENSION: ROLE OF S. NERVOUS SYSTEM
    Joel Dimsdale; Fiscal Year: 1991
    ..All patients will be admitted for a 2 day stay in the Clinical Research Center...
  4. Sleep Apnea and Hypertension: Role of SNS
    Joel Dimsdale; Fiscal Year: 2005
    ....
  5. SLEEP APNEA & HYPERTENSION--ROLE OF SYMP NERVOUS SYSTEM
    Joel Dimsdale; Fiscal Year: 2000
    ..Sleep will be characterized with polysomnography. The effect of nocturnal oxygen treatment will be studied in terms of patient satisfaction, compliance, and quality of life. ..
  6. STRESS, BLOOD PRESSURE AND ETHNICITY
    Joel Dimsdale; Fiscal Year: 2000
    ..Psychological characterization will include assessment of life stressors and job stress, mood, anger/hostility, and social desirability. ..
  7. STRESS, BLOOD PRESSURE AND ETHNICITY
    Joel Dimsdale; Fiscal Year: 2001
    ..Psychological characterization will include assessment of life stressors and job stress, mood, anger/hostility, and social desirability. ..
  8. Sleep Apnea and Hypertension: Role of SNS
    Joel Dimsdale; Fiscal Year: 2004
    ....
  9. STRESS, BLOOD PRESSURE AND ETHNICITY
    Joel Dimsdale; Fiscal Year: 2002
    ..Psychological characterization will include assessment of life stressors and job stress, mood, anger/hostility, and social desirability. ..
  10. Sleep Apnea and Hypertension: Role of SNS
    Joel Dimsdale; Fiscal Year: 2006
    ....
  11. STRESS PHYSIOLOGY, DIETARY SALT, AND HYPERTENSION
    Joel Dimsdale; Fiscal Year: 1993
    ..This hormone has unusual characteristics which are apparently opposite those of norepinephrine in terms of sodium excretion and vasodilation...
  12. Burden of Obstructive Sleep Apnea in Stroke (BOSAST)
    Joel E Dimsdale; Fiscal Year: 2010
    ..Obstructive sleep apnea has similar symptoms and is also very common in stroke patients. This study will determine if treating apnea in stroke patients will improve these burdens. ..
  13. Effects of Opioids on Sleep and Fatigue
    Joel Dimsdale; Fiscal Year: 2004
    ..abstract_text> ..
  14. STRESS, BLOOD PRESSURE AND ETHNICITY
    Joel Dimsdale; Fiscal Year: 2007
    ..We hypothesize that adversity has a stronger impact on cardiovascular pathophysiology than does ethnicity. Keywords: hypertension, ethnicity, sleep, inflammation, sympathetic nervous system, social class ..
  15. Burden of Obstructive Sleep Apnea in Stroke (BOSAST)
    Joel Dimsdale; Fiscal Year: 2009
    ..Obstructive sleep apnea has similar symptoms and is also very common in stroke patients. This study will determine if treating apnea in stroke patients will improve these burdens. ..
  16. STRESS, BLOOD PRESSURE AND ETHNICITY
    Joel Dimsdale; Fiscal Year: 2005
    ..The study scrutinizes sleep, inflammation, vasodilation, autonomic functioning, and baroreflex regulation. We hypothesize that adversity has a stronger impact on cardiovascular pathophysiology than does ethnicity. ..
  17. Sleep Apnea and Hypertension: Role of SNS
    Joel Dimsdale; Fiscal Year: 2007
    ....
  18. STRESS, BLOOD PRESSURE AND ETHNICITY
    Joel Dimsdale; Fiscal Year: 2007
    ..The study scrutinizes sleep, inflammation, vasodilation, autonomic functioning, and baroreflex regulation. We hypothesize that adversity has a stronger impact on cardiovascular pathophysiology than does ethnicity. ..
  19. STRESS, BLOOD PRESSURE AND ETHNICITY
    Joel Dimsdale; Fiscal Year: 2006
    ..The study scrutinizes sleep, inflammation, vasodilation, autonomic functioning, and baroreflex regulation. We hypothesize that adversity has a stronger impact on cardiovascular pathophysiology than does ethnicity. ..
  20. STRESS, BLOOD PRESSURE AND ETHNICITY
    Joel Dimsdale; Fiscal Year: 2009
    ..The study scrutinizes sleep, inflammation, vasodilation, autonomic functioning, and baroreflex regulation. We hypothesize that adversity has a stronger impact on cardiovascular pathophysiology than does ethnicity. ..
  21. STRESS, BLOOD PRESSURE AND ETHNICITY
    Joel Dimsdale; Fiscal Year: 2003
    ..Psychological characterization will include assessment of life stressors and job stress, mood, anger/hostility, and social desirability. ..
  22. SLEEP APNEA & HYPERTENSION--ROLE OF SYMP NERVOUS SYSTEM
    Joel Dimsdale; Fiscal Year: 2002
    ..Sleep will be characterized with polysomnography. The effect of nocturnal oxygen treatment will be studied in terms of patient satisfaction, compliance, and quality of life. ..
  23. STRESS PHYSIOLOGY, DIETARY SALT, AND HYPERTENSION
    Joel Dimsdale; Fiscal Year: 1991
    ..This hormone has unusual characteristics which are apparently opposite those of norepinephrine in terms of sodium excretion and vasodilation...
  24. STRESS PHYSIOLOGY, DIETARY SALT, AND HYPERTENSION
    Joel Dimsdale; Fiscal Year: 1990
    ..This hormone has unusual characteristics which are apparently opposite those of norepinephrine in terms of sodium excretion and vasodilation...
  25. SLEEP APNEA & HYPERTENSION--ROLE OF S. NERVOUS SYSTEM
    Joel Dimsdale; Fiscal Year: 1992
    ..All patients will be admitted for a 2 day stay in the Clinical Research Center...
  26. SLEEP APNEA & HYPERTENSION: ROLE OF S. NERVOUS SYSTEM
    Joel Dimsdale; Fiscal Year: 1993
    ..All patients will be admitted for a 2 day stay in the Clinical Research Center...
  27. SLEEP APNEA & HYPERTENSION--ROLE OF SYMP NERVOUS SYSTEM
    Joel Dimsdale; Fiscal Year: 2001
    ..Sleep will be characterized with polysomnography. The effect of nocturnal oxygen treatment will be studied in terms of patient satisfaction, compliance, and quality of life. ..
  28. SLEEP APNEA & HYPERTENSION--ROLE OF SYMP NERVOUS SYSTEM
    Joel Dimsdale; Fiscal Year: 1999
    ..Sleep will be characterized with polysomnography. The effect of nocturnal oxygen treatment will be studied in terms of patient satisfaction, compliance, and quality of life. ..
  29. STRESS PHYSIOLOGY, DIETARY SALT, AND HYPERTENSION
    Joel Dimsdale; Fiscal Year: 1999
    ..Similar variables will be studied while the individual performs mildly stressful tasks. ..