Detail Information
Publications
rtREV: an amino acid substitution matrix for inference of retrovirus and reverse transcriptase phylogenyMatthew W Dimmic
Biophysics Research Division, University of Michigan, 930 North University Avenue, Ann Arbor, MI 48109 1055, USA
J Mol Evol 55:65-73. 2002..We provide evidence that rtREV is a more realistic evolutionary model for analyses of the pol gene, although it is inapplicable to analyses involving the gag gene...
Dimerization in aminergic G-protein-coupled receptors: application of a hidden-site class model of evolutionOrkun S Soyer
Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA
Biochemistry 42:14522-31. 2003..On the basis of these findings, we propose an experimentally testable dimerization mechanism, involving interactions among different combinations of these helices in different families of aminergic GPCRs...
Detecting coevolving amino acid sites using Bayesian mutational mappingMatthew W Dimmic
Department of Biological Statistics and Computational Biology, Cornell University Ithaca, NY 13101, USA
Bioinformatics 21:i126-35. 2005..A coevolutionary Markov model for codon substitution is also described, and this model is used as the basis of several test statistics...
