Research Topics
| Joseph DiFranzaSummaryAffiliation: University of Massachusetts Medical School Country: USA Publications
Research Grants
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Detail Information
Publications
The loss of autonomy over smoking in relation to lifetime cigarette consumptionW W Sanouri A Ursprung
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Addict Behav 35:14-8. 2010..Diminished autonomy after one or two cigarettes, and DSM-IV nicotine dependence after 10-19, support the sensitization-homeostasis theory of nicotine addiction that the addiction process is initiated by the first few cigarettes...- The assessment of tobacco dependence in young users of smokeless tobaccoJoseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655, USA
Tob Control 21:471-6. 2012..Dippers and smokers were also compared in relation to dependence, the pleasure derived from using tobacco and the latency to the onset of withdrawal... - Which interventions against the sale of tobacco to minors can be expected to reduce smoking?Joseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Avenue, Worcester, Massachusetts 01655, USA
Tob Control 21:436-42. 2012..The object of this study was to determine if disrupting the sale of tobacco to minors can be expected to reduce tobacco use by youths... - Best practices for enforcing state laws prohibiting the sale of tobacco to minorsJoseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA 01655, USA
J Public Health Manag Pract 11:559-65. 2005..To determine best practices for enforcing public health laws prohibiting the sale of tobacco to minors... - Tobacco promotion and the initiation of tobacco use: assessing the evidence for causalityJoseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA 01655, USA
Pediatrics 117:e1237-48. 2006..We sought to determine whether there is evidence of a causal link between exposure to tobacco promotion and the initiation of tobacco use by children... - Thwarting science by protecting the received wisdom on tobacco addiction from the scientific methodJoseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA, USA
Harm Reduct J 7:26. 2010.... - Sensitization to nicotine: how the animal literature might inform future human researchJoseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA 01655
Nicotine Tob Res 9:9-20. 2007..Sensitization is incorporated into two theories of addiction: incentive-sensitization and sensitization-homeostasis. Whether sensitization occurs in humans and how it is expressed is unclear, as is its role in human addiction... - Symptoms of tobacco dependence after brief intermittent use: the Development and Assessment of Nicotine Dependence in Youth-2 studyJoseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA 01655, USA
Arch Pediatr Adolesc Med 161:704-10. 2007..The first study found that symptoms of dependence commonly appeared soon after the onset of intermittent smoking... - A systematic review of the International Classification of Diseases criteria for the diagnosis of tobacco dependenceJoseph DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA 01655, United States
Addict Behav 35:805-10. 2010..We contrast the utility of the ICD-TD criteria to an approach of diagnosing tobacco addiction on the basis of a single criterion of a compulsion to use tobacco... - New insights into the compulsion to use tobacco from an adolescent case-seriesJoseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Avenue, Worcester, Massachusetts 01655, USA
J Adolesc 33:209-14. 2010..Wanting, craving or needing tobacco, as described in this study, are pathognomonic for a compulsion to use tobacco... - Susceptibility to nicotine dependence: the Development and Assessment of Nicotine Dependence in Youth 2 studyJoseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Ave, Worcester, MA 01655, USA
Pediatrics 120:e974-83. 2007..We studied a cohort of 1246 public school 6th-graders in 6 Massachusetts communities (mean age at baseline: 12.2 years)... - Hooked from the first cigaretteJoseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA 01655, USA
J Fam Pract 56:1017-22. 2007 - A systematic review of the Diagnostic and Statistical Manual diagnostic criteria for nicotine dependenceJoseph DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01655, USA
Addict Behav 35:373-82. 2010..However, the data do not support the central premise of a 3-symptom diagnostic threshold, and no data establish that the DSM-ND criteria provide an accurate diagnosis of nicotine dependence... - The Autonomy Over Smoking ScaleJoseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA 01655, USA
Psychol Addict Behav 23:656-65. 2009.... - Let the children be heard: lessons from studies of the early onset of tobacco addictionJoseph R DiFranza
University of Massachusetts Medical School, Department of Family Medicine and Community Health, 55 Lake Ave, Worcester, MA 01655, USA
Pediatrics 121:623-4. 2008 - The latency to the onset of nicotine withdrawal: a test of the sensitization-homeostasis theoryJoseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Addict Behav 33:1148-53. 2008..The LTW correlated inversely with monthly cigarette consumption (Kendall's tau b=-.53, P<.001) and the duration of smoking (Kendall's tau b=-.25, P<.001) as predicted by the sensitization-homeostasis theory... - The developmental sequence of tobacco withdrawal symptoms of wanting, craving and needingJoseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA 01655, USA
Pharmacol Biochem Behav 100:494-7. 2012..The objective of the current study was to determine if this observation would be confirmed by a second case series... - Enforcement of underage sales laws as a predictor of daily smoking among adolescents: a national studyJoseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA, USA
BMC Public Health 9:107. 2009..Our objective was to determine if state compliance with tobacco sales laws is associated with a decreased risk of current daily smoking among adolescents... - A sensitization-homeostasis model of nicotine craving, withdrawal, and tolerance: integrating the clinical and basic science literatureJoseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA 01655, USA
Nicotine Tob Res 7:9-26. 2005..It provides a framework for theory-based research... - The federal initiative to halt the sale of tobacco to children--the Synar Amendment, 1992-2000: lessons learnedJ R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Tob Control 14:93-8. 2005..The Synar Amendment was enacted by the US Congress in 1992 to require states and territories to establish and enforce laws prohibiting the sale of tobacco to minors... - Measuring the loss of autonomy over nicotine use in adolescents: the DANDY (Development and Assessment of Nicotine Dependence in Youths) studyJoseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Ave, Worcester, MA 01655, USA
Arch Pediatr Adolesc Med 156:397-403. 2002..We propose that nicotine dependence begins when autonomy is lost, ie, when the sequelae of tobacco use, either physical or psychological, present a barrier to quitting... - Sources of tobacco for youths in communities with strong enforcement of youth access lawsJ R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01655, USA
Tob Control 10:323-8. 2001..To determine how youths obtain tobacco in communities with strong enforcement of tobacco sales laws... - Implications of the autonomy theory of nicotine dependenceJoseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, Massachusetts, USA
MedGenMed 4:8. 2002 - Does progression through the stages of physical addiction indicate increasing overall addiction to tobacco?Joseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
Psychopharmacology (Berl) 219:815-22. 2012..As physical addiction advances, the desire to smoke changes in quality and intensity from wanting, to craving, to needing. A prior study in adolescents suggested that this progression signifies increasing addiction... - Prenatal and postnatal environmental tobacco smoke exposure and children's healthJoseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Pediatrics 113:1007-15. 2004.... - Trait anxiety and nicotine dependence in adolescents: a report from the DANDY studyJoseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01655, USA
Addict Behav 29:911-9. 2004..Trait anxiety and relaxation in response to the first dose of nicotine were unrelated and appear to be independent risk factors for the development of nicotine dependence and a reliance on tobacco to cope with stress... - Is the standard compliance check protocol a valid measure of the accessibility of tobacco to underage smokers?J R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Tob Control 10:227-32. 2001..To determine if the standard compliance check protocol is a valid measure of the experience of underage smokers when purchasing tobacco in unfamiliar communities... - Measuring statewide merchant compliance with tobacco minimum age laws: the Massachusetts experienceJ R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical Center, Worcester, MA 01655, USA
Am J Public Health 91:1124-5. 2001..This study evaluated merchant compliance with laws prohibiting the sale of tobacco to minors in Massachusetts... - State and federal compliance with the Synar amendment: federal fiscal year 1997J R DiFranza
Department of Family Medicine and Community Health, 55 Lake Ave, University of Massachusetts Medical School, Worcester, MA 01655
Arch Pediatr Adolesc Med 154:936-42. 2000..The Synar Amendment requires states and territories to enact a law prohibiting the sale of tobacco to minors and to enforce that law in a manner that could reasonably be expected to decrease the availability of tobacco to minors... - Development of symptoms of tobacco dependence in youths: 30 month follow up data from the DANDY studyJ R DiFranza
University of Massachusetts Medical School, Worcester, Massachusetts, USA Harvard Medical School, Massachusetts, USA University of London, London, UK
Tob Control 11:228-35. 2002..To determine if there is a minimum duration, frequency or quantity of tobacco use required to develop symptoms of dependence... - Recollections and repercussions of the first inhaled cigaretteJoseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01655, USA
Addict Behav 29:261-72. 2004..It has not been determined if a youth's reaction to the first smoking experience is predictive of future nicotine dependence, or whether the impact of the first cigarette can be altered by manipulating levels of tar, nicotine and menthol... - Perceived accessibility as a predictor of youth smokingChyke A Doubeni
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA 01655, USA
Ann Fam Med 6:323-30. 2008..The objective of this study was to determine whether perceived accessibility predicted future smoking among youths... - Screening adolescents for nicotine dependence: the Hooked On Nicotine ChecklistKatherine Carter Wheeler
Department of Biology/Biotechnology, Worcester Polytechnic Institute, 55 Lake Avenue, Worcester, MA 01655, USA
J Adolesc Health 35:225-30. 2004..70, p <.001, n = 88). CONCLUSIONS: Adding the HONC to routine adolescent health examinations, health classes, and prevention programs may make adolescents more aware of their symptoms of ND and enable intervention before ND progresses... - Preventing cancer by controlling youth tobacco useJoseph R DiFranza
Department of Family and Community Medicine, University of Massachusetts Medical Center, 55 Lake Ave, Worcester, MA 01655, USA
Semin Oncol Nurs 19:261-7. 2003..IMPLICATIONS FOR NURSING PRACTICE: Nurses have an important role to play in the battle against tobacco-induced malignancies through collaboration with community efforts or state initiatives... - Measuring adults' loss of autonomy over nicotine use: the Hooked on Nicotine ChecklistRobert J Wellman
Behavioral Sciences Department, Fitchburg State College, MA, USA
Nicotine Tob Res 7:157-61. 2005..The HONC appears to be psychometrically sound in both adolescents and adults. It is a reliable and valid measure of lost autonomy for both novice and experienced smokers, and it allows for comparisons between these populations... - Smoking prevention and cessation intervention delivery by pediatric providers, as assessed with patient exit interviewsLori Pbert
Division of Preventive and Behavioral Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Pediatrics 118:e810-24. 2006..The goal was to evaluate the degree to which a smoking prevention and cessation intervention was delivered by providers to adolescents in the pediatric office setting... - Parent's socioeconomic status, adolescents' disposable income, and adolescents' smoking status in MassachusettsElpidoforos S Soteriades
Department of Health and Social Behavior, Harvard School of Public Health, Boston, MA, USA
Am J Public Health 93:1155-60. 2003..Parental smoking status was a mediator of these associations. CONCLUSIONS: Parental SES is inversely associated with adolescent smoking. Parental smoking is a mediator but does not fully explain the association... - Hooked from the first cigaretteJoseph R DiFranza
University of Massachusetts Medical School, Worcester, USA
Sci Am 298:82-7. 2008..These adaptations lead to withdrawal symptoms when the effects of nicotine wear off. The results highlight the importance of boosting government funding for antismoking campaigns, particularly those aimed at youngsters... - Perceived accessibility of cigarettes among youth: a prospective cohort studyChyke A Doubeni
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Am J Prev Med 36:239-42. 2009..This study examines the determinants of perceived accessibility from the perspective of a longitudinal study... - Might expectations explain early self-reported symptoms of nicotine dependence?W W Sanouri A Ursprung
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Addict Behav 34:227-31. 2009..While youth do share expectations about nicotine dependence, it is not the expectation that they will become dependent; it is the expectation that if they smoke they will be able to quit whenever they want... - Imaging brain activation in nicotine-sensitized ratsZhixin Li
Department of Psychiatry, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
Brain Res 1199:91-9. 2008.... - Early course of nicotine dependence in adolescent smokersChyke A Doubeni
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Ave North, Worcester, MA 01655, USA
Pediatrics 125:1127-33. 2010..The goal was to characterize the early course of nicotine dependence... - Tobacco chippers report diminished autonomy over smokingRobert J Wellman
University of Massachusetts Medical School, Department of Family Medicine and Community Health, Worcester 01655, United States
Addict Behav 31:717-21. 2006..Although chippers may not warrant a dependence diagnosis, they may benefit from help with cessation. Autonomy over smoking may be a more useful basis than cigarette consumption rates for classifying smokers... - A comparison of the psychometric properties of the hooked on nicotine checklist and the modified Fagerström tolerance questionnaireRobert J Wellman
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
Addict Behav 31:486-95. 2006..The most important advantage of the HONC is that it is measuring a clearly defined concept, diminished autonomy over tobacco, which begins when the sequelae of tobacco use present a barrier to quitting... - Effect of a pediatric practice-based smoking prevention and cessation intervention for adolescents: a randomized, controlled trialLori Pbert
Division of Preventive and Behavioral Medicine, University of Massachusetts Medical School, 55 Lake Ave North, Worcester, MA 01655, USA
Pediatrics 121:e738-47. 2008..The purpose of this work was to determine whether a pediatric practice-based smoking prevention and cessation intervention increases abstinence rates among adolescents... - The effect of abstinence on cigarette consumption upon the resumption of smokingRobert J Wellman
University of Massachusetts Medical School, Department of Family Medicine and Community Health, Worcester 01655, United States
Addict Behav 31:711-6. 2006..The shapes of the observed trajectories suggest that more than one process may be at work. Prospective studies are needed to confirm these findings... - The relationship between level of cigarette consumption and latency to the onset of retrospectively reported withdrawal symptomsW W S A Fernando
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA, 01655, USA
Psychopharmacology (Berl) 188:335-42. 2006..Consistent with the sensitization-homeostasis theory, low doses of nicotine can suppress withdrawal symptoms over long periods... - The extent to which tobacco marketing and tobacco use in films contribute to children's use of tobacco: a meta-analysisRobert J Wellman
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA 01655, USA
Arch Pediatr Adolesc Med 160:1285-96. 2006..To quantify the effect of exposure on initiation of tobacco use among adolescents... - Symptoms of diminished autonomy over cigarettes with non-daily useJudith A Savageau
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Int J Environ Res Public Health 6:25-35. 2009..9% of subjects who smoked less often than once per week. Among subjects who had not smoked 20 cigarettes in their lifetime, 12.6% had symptoms of nicotine withdrawal, and 25% had made an unsuccessful quit attempt... - The state of office-based interventions for youth tobacco useLori Pbert
Division of Preventive and Behavioral Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Pediatrics 111:e650-60. 2003..Pediatricians and other clinicians can and should play an important role in treating tobacco dependence in youths... - A gadget can't fix what's wrong with the tobacco distribution systemJoseph R DiFranza
University of Massachusetts Medical School, Worcester 01655, USA
J Public Health Policy 24:269-73. 2003 - A comparison of the Hooked on Nicotine Checklist and the Fagerström Test for Nicotine Dependence in adult smokersRobert J Wellman
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA 01655, USA
Nicotine Tob Res 8:575-80. 2006..The HONC is uniquely suited for use with smokers whose cigarette consumption is low... - Children's loss of autonomy over smoking: the Global Youth Tobacco SurveyElpidoforos S Soteriades
Cyprus Institute of Biomedical Sciences CIBS, Department of Occupational and Environmental Medicine, Nicosia, Cyprus
Tob Control 20:201-6. 2011..Empirical data suggest that children with infrequent tobacco use have difficulty quitting smoking... - Adolescents' acquisition of cigarettes through noncommercial sourcesJoseph R DiFranza
J Adolesc Health 32:331-2; author reply 332. 2003 - Tobacco control for clinicians who treat adolescentsJames D Sargent
Dartmouth Medical School, Hanover, NH, USA
CA Cancer J Clin 53:102-23. 2003.... - Time to re-examine old definitions of nicotine dependenceJoseph R DiFranza
Nicotine Tob Res 10:1109-11. 2008 - Early dating and smoking initiation: Some thoughts about a common causeJoseph R DiFranza
Addiction 101:1682-3. 2006 - Diminished autonomy over tobacco can appear with the first cigarettesRobert Scragg
Epidemiology and Statistics Section, School of Population Health, University of Auckland, New Zealand
Addict Behav 33:689-98. 2008..These data suggest that smoking one cigarette in total can prompt a loss of autonomy... - Nicotine withdrawal in subthreshold smokersJoseph R DiFranza
Addiction 103:511-2; author reply 512-3. 2008 - Symptoms of nicotine dependence and other predictors of student smoking at school: implications for school smoking policyElpidoforos S Soteriades
Harvard School of Public Health, Dept of Environmental Health, 665 Huntington Ave, Boston, MA 02115, USA
J Sch Health 73:154-8. 2003..Disciplinary action against students caught violating school smoking policies should be supplemented with an offer of treatment for nicotine dependence... - R-rated film viewing and adolescent smokingMurray Laugesen
Health New Zealand
Prev Med 45:454-9. 2007..As smoking is very common in R-rated films, we sought to determine if viewing R-rated films is associated with adolescent smoking...
Research Grants
- The Transition of Nicotine DependenceJoseph DiFranza; Fiscal Year: 2005..A new theory-based measure of early dependence for youths will be tested against established measures of dependence. ..