Research Topics
| K N DietrichSummaryAffiliation: University of Cincinnati Country: USA Publications
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Publications
Early exposure to lead and juvenile delinquencyK N Dietrich
Department of Environmental Health, Division of Epidemiology and Biostatistics, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0056, USA
Neurotoxicol Teratol 23:511-8. 2001....
Effect of chelation therapy on the neuropsychological and behavioral development of lead-exposed children after school entryKim N Dietrich
University of Cincinnati College of Medicine, Department of Environmental Health, Cincinnati, Ohio 45267 0056, USA
Pediatrics 114:19-26. 2004..96-2.12 micromol/L) at 12 to 33 months of age has neurodevelopmental benefits at age 7 years...
Cognitive development of lead exposed children from ages 6 to 15 years: an application of growth curve analysisJuliet M Coscia
Children s Hospital Medical Center, Cincinnati, OH, USA
Child Neuropsychol 9:10-21. 2003..The findings suggest that lead negatively impacts the developmental progression of specific cognitive skills from childhood through adolescence...
Effect of succimer chelation therapy on postural balance and gait outcomes in children with early exposure to environmental leadAmit Bhattacharya
Department of Environmental Health, University of Cincinnati Medical College, Cincinnati, OH 45267 0056, USA
Neurotoxicology 28:686-95. 2007....
Effect of early lead exposure on the maturation of children's postural balance: a longitudinal studyAmit Bhattacharya
Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0056, USA
Neurotoxicol Teratol 28:376-85. 2006..As these subjects are now adults in their early to mid-twenties, poor postural balance may impact their daily living tasks and pose a higher risk of potential injuries at home and work...
Low-level environmental lead exposure and children's intellectual function: an international pooled analysisBruce P Lanphear
Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
Environ Health Perspect 113:894-9. 2005..5 microg/dL (p = 0.015). We conclude that environmental lead exposure in children who have maximal blood lead levels < 7.5 microg/dL is associated with intellectual deficits...
Lead-based paint health risk assessment in dependent children living in military housingDavis M Stroop
Department of Environmental Health, College of Medicine, University of Cincinnati, Cincinnati, OH, USA
Public Health Rep 117:446-52. 2002..S. military installation and determine blood lead (PbB) levels in children ages 6 years or younger residing in these housing units...
Early exposure to lead and neuropsychological outcome in adolescenceM Douglas Ris
Department of Pediatrics and the Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
J Int Neuropsychol Soc 10:261-70. 2004..These results also underscore the complexity of models of neurobehavioral development, and the modest predictive power of any single determinant...
Interactive effects of a DRD4 polymorphism, lead, and sex on executive functions in childrenTanya E Froehlich
Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
Biol Psychiatry 62:243-9. 2007..Prior studies have examined independent effects of a dopamine receptor D4 polymorphism (DRD4-7) and lead exposure on executive functions but not their interaction or the role of sex as a modifier of their effects...
Environmental neurotoxinsBruce P Lanphear
Department of Pediatrics, Cincinnati Children's Environmental Health Center, Cincinnati Children's Hospital, Medical Center University of Cincinnati, Cincinnati, Ohio, USA
Pediatr Rev 26:191-7; quiz 198. 2005
The influence of age of lead exposure on adult gray matter volumeChristopher J Brubaker
Cincinnati Children s Environmental Health Center, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA
Neurotoxicology 31:259-66. 2010..This study demonstrates that maximum blood lead levels do not fully account for gray matter changes associated with childhood lead exposure, particularly in the frontal lobes of young men...
Age of greatest susceptibility to childhood lead exposure: a new statistical approachRichard W Hornung
Cincinnati Children s Environmental Health Center, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
Environ Health Perspect 117:1309-12. 2009..Susceptibility to lead toxicity is often assumed to be greatest during early childhood (e.g., 2 years of age), but recent studies suggest that blood lead concentrations (BPb) taken at 5-7 years of age are more strongly associated with IQ...
Altered myelination and axonal integrity in adults with childhood lead exposure: a diffusion tensor imaging studyChristopher J Brubaker
Cincinnati Children s Environmental Health Center at the Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA
Neurotoxicology 30:867-75. 2009..This study indicates that childhood lead exposure is associated with a significant and persistent impact on white matter microstructure as quantified with diffusivity changes suggestive of altered myelination and axonal integrity...
The impact of early childhood lead exposure on brain organization: a functional magnetic resonance imaging study of language functionWeihong Yuan
Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA
Pediatrics 118:971-7. 2006..CONCLUSION: This study indicates that childhood lead exposure has a significant and persistent impact on brain reorganization associated with language function...
Postural stability in children with autism spectrum disorderCynthia A Molloy
University of Cincinnati College of Medicine, Department of Pediatrics, Division of Developmental Disabilities, Center for Epidemiology and Biostatistics, Cincinnati, Ohio 45229 3039, USA
J Autism Dev Disord 33:643-52. 2003..These results are consistent with a deficit in the integration of visual, vestibular, and somatosensory input to maintain postural orientation...
The conundrum of unmeasured confounding: Comment on: "Can some of the detrimental neurodevelopmental effects attributed to lead be due to pesticides? by Brian Gulson"Bruce P Lanphear
Cincinnati Children s Environmental Health Center, Department of Pediatrics and of Environmental Health, Cincinnati Children s Hospital Medical Center, The University of Cincinnati, Cincinnati, Ohio, USA
Sci Total Environ 396:196-200. 2008..The alternative, to perpetually permit children to be exposed to lead and other emerging toxicants, is both absurd and unacceptable...
Decreased brain volume in adults with childhood lead exposureKim M Cecil
Cincinnati Children s Environmental Health Center, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, United States of America
PLoS Med 5:e112. 2008..In this study, we examined the relationship between childhood lead exposure and adult brain volume using magnetic resonance imaging (MRI). We also explored how volume changes correlate with historic neuropsychological assessments...
Do children with falling blood lead levels have improved cognition?Xianchen Liu
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
Pediatrics 110:787-91. 2002..Exposure to lead at levels encountered by urban children impairs cognitive development. An observational study suggested improvement in IQ when blood lead level fell, but the only randomized trial of chelation showed no benefit in IQ...
Lead exposure, IQ, and behavior in urban 5- to 7-year-olds: does lead affect behavior only by lowering IQ?Aimin Chen
Epidemiology Branch, National Institute on Environmental Health Sciences, Research Triangle Park, NC 27709, USA
Pediatrics 119:e650-8. 2007..In addition, either peak blood lead concentration, usually at 2 years old, or the lower blood lead level measured at school age may be the most relevant. Few studies have all of this information...
Executive functioning and memory for the Rey-Osterreith complex figure task among community adolescentsDean W Beebe
Psychology Division, Cincinnati Children s Hospital Medical Center, Ohio 45229 3039, USA
Appl Neuropsychol 11:91-8. 2004..Even so, data supported the convergent validity of the DSS system as a reflection of visual-constructional ability and provided evidence of the importance of organizational strategies to visual memory among adolescents...
IQ and blood lead from 2 to 7 years of age: are the effects in older children the residual of high blood lead concentrations in 2-year-olds?Aimin Chen
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health DHHS, Research Triangle Park, NC 27709, USA
Environ Health Perspect 113:597-601. 2005..The effect of concurrent blood level on IQ may therefore be greater than currently believed...
Association of prenatal and childhood blood lead concentrations with criminal arrests in early adulthoodJohn Paul Wright
Cincinnati Children s Environmental Health Center, Division of Criminal Justice, University of Cincinnati, Cincinnati, Ohio, United States of America
PLoS Med 5:e101. 2008..The objective of this study was to determine if prenatal and childhood blood lead concentrations are associated with arrests for criminal offenses...
Injury trends for adolescents with early childhood lead exposureLaurel D Kincl
Labor Education and Research Center, University of Oregon, Eugene, Oregon 97403 1289, USA
J Adolesc Health 39:604-6. 2006..Results demonstrated that elevated childhood blood lead concentrations were significantly related to injury variables. Further study is necessary to understand adolescent health and safety implications...
Association of environmental toxicants and conduct disorder in U.S. children: NHANES 2001-2004Joseph M Braun
Department of Epidemiology, University of North Carolina Chapel Hill, Chapel Hill, NC 27599 7435, USA
Environ Health Perspect 116:956-62. 2008..The purpose of this study was to examine the association of tobacco smoke and environmental lead exposure with conduct disorder (CD)...
Prevention of lead toxicity in US childrenBruce P Lanphear
Cincinnati Children s Environmental Health Center, Department of Pediatrics, Children s Hospital Medical Center, Ohio 45229, USA
Ambul Pediatr 3:27-36. 2003..This article reviews the epidemiology and control of childhood lead exposure, focusing especially on steps necessary to shift toward primary prevention...
