Research Topics
| Binh An DiepSummaryAffiliation: University of California Country: USA Publications
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Publications
Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureusBinh An Diep
Department of Medicine, University of California, San Francisco General Hospital, San Francisco, CA 94143, USA
Lancet 367:731-9. 2006..Our aim was to sequence its genome and compare it with those of other strains of S aureus to try to identify genes responsible for its distinctive epidemiological and virulence properties...
Emergence of multidrug-resistant, community-associated, methicillin-resistant Staphylococcus aureus clone USA300 in men who have sex with menBinh An Diep
University of California, San Francisco, San Francisco, CA 94110, USA
Ann Intern Med 148:249-57. 2008..Infection with multidrug-resistant, community-associated, methicillin-resistant Staphylococcus aureus (MRSA) has been reported but seems to be isolated...
Roles of 34 virulence genes in the evolution of hospital- and community-associated strains of methicillin-resistant Staphylococcus aureusBinh An Diep
Division of Infectious Diseases, Department of Medicine, University of California, San Francisco, USA
J Infect Dis 193:1495-503. 2006..CONCLUSIONS: The horizontal transfer of virulence genes, although infrequent, is epidemiologically associated with the emergence of new virulent strains of MRSA...
Population dynamics of nasal strains of methicillin-resistant Staphylococcus aureus--and their relation to community-associated disease activityErica S Pan
Department of Medicine, Division of Infectious Diseases, University of California, San Francisco, California, USA
J Infect Dis 192:811-8. 2005....
Contribution of Panton-Valentine leukocidin in community-associated methicillin-resistant Staphylococcus aureus pathogenesisBinh An Diep
Division of Infectious Diseases, Department of Medicine, San Francisco General Hospital, University of California San Francisco, San Francisco, California, United States of America
PLoS ONE 3:e3198. 2008..Taken together, our data indicate a modest and transient positive effect of PVL in the acute phase of bacteremia, thereby providing evidence that PVL contributes to CA-MRSA pathogenesis...
Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injuryBinh An Diep
Division of Infectious Diseases, Department of Medicine, University of California, San Francisco, CA 94110, USA
Proc Natl Acad Sci U S A 107:5587-92. 2010..These findings provide insights into the mechanism of PVL-induced lung injury and inflammation and demonstrate the utility of the rabbit for studying PVL-mediated pathogenesis...
Community-adapted methicillin-resistant Staphylococcus aureus (MRSA): population dynamics of an expanding community reservoir of MRSAHeather A Carleton
Department of Medicine, Division of Infectious Diseases, University of California, San Francisco, San Francisco, California 94110, USA
J Infect Dis 190:1730-8. 2004..The longitudinal results linked the dramatic increase in MRSA infections to an expanding community reservoir of MRSA genotypes with intrinsic community survival advantage...
A population-based study of the incidence and molecular epidemiology of methicillin-resistant Staphylococcus aureus disease in San Francisco, 2004-2005Catherine Liu
Div of Infectious Diseases, University of California, San Francisco, 513 Parnassus Ave, S 380, Box 0654, San Francisco, CA 94143, USA
Clin Infect Dis 46:1637-46. 2008..Our objective was to perform a population-based survey of the clinical and molecular epidemiology of MRSA disease in San Francisco, California...
Long-term follow-up of methicillin-resistant Staphylococcus aureus molecular epidemiology after emergence of clone USA300 in San Francisco jail populationsPierre Tattevin
Department of Medicine, Division of Infectious Diseases, San Francisco General Hospital, San Francisco, California 94143 0811, USA
J Clin Microbiol 46:4056-7. 2008..Strain USA300, first encountered in 2001, accounted for 82.1% (412/502) of MRSA infections. Non-USA300 MRSA strains were rarely found after 2005 (one isolate in 2006, three in 2007)...
The role of virulence determinants in community-associated MRSA pathogenesisBinh An Diep
Division of Infectious Diseases, Department of Medicine, University of California, San Francisco, 1001 Potrero Avenue, Box 0811, San Francisco, CA 94110, USA
Trends Microbiol 16:361-9. 2008..Here, we discuss the roles of PVL, the arginine catabolic mobile element and phenol-soluble modulins in the pathogenesis of prevalent CA-MRSA strains...
Widespread skin and soft-tissue infections due to two methicillin-resistant Staphylococcus aureus strains harboring the genes for Panton-Valentine leucocidinBinh An Diep
Division of Infectious Diseases, School of Public Health, University of California, Berkeley, California 94720, USA
J Clin Microbiol 42:2080-4. 2004..0001). There is evidence of clonal replacement over the period from 1999 to 2002, with one of these two clonal groups being supplanted by the other...
Concurrent epidemics of skin and soft tissue infection and bloodstream infection due to community-associated methicillin-resistant Staphylococcus aureusPierre Tattevin
Division of Infectious Diseases, Department of Medicine, University of California, San Francisco, USA
Clin Infect Dis 55:781-8. 2012....
The arginine catabolic mobile element and staphylococcal chromosomal cassette mec linkage: convergence of virulence and resistance in the USA300 clone of methicillin-resistant Staphylococcus aureusBinh An Diep
Division of Infectious Diseases, Department of Medicine, San Francisco General Hospital, University of California, San Francisco 94110, USA
J Infect Dis 197:1523-30. 2008..These data are consistent with a model in which ACME enhances growth and survival of USA300, allowing for genetic "hitchhiking" of SCCmec. SCCmec in turn protects against exposure to beta-lactams...
Cross-talk between Staphylococcus aureus leukocidins-intoxicated macrophages and lung epithelial cells triggers chemokine secretion in an inflammasome-dependent mannerMagali Perret
Universite de Lyon, France
Cell Microbiol 14:1019-36. 2012....
Clonal characterization of Staphylococcus aureus by multilocus restriction fragment typing, a rapid screening approach for molecular epidemiologyBinh An Diep
Division of Infectious Diseases, School of Public Health, University of California, Berkeley, California 94720, USA
J Clin Microbiol 41:4559-64. 2003..In short, MLRFT provides a convenient alternative to MLST and PFGE because it requires minimal laboratory facilities and is relatively simple and inexpensive to perform...
Clonal composition and community clustering of drug-susceptible and -resistant Escherichia coli isolates from bloodstream infectionsSheila Adams-Sapper
School of Public Health, Division of Infectious Diseases and Vaccinology, University of California, Berkeley, Berkeley, California, USA
Antimicrob Agents Chemother 57:490-7. 2013..coli regardless of their drug resistance...
Recurrence of skin and soft tissue infection caused by methicillin-resistant Staphylococcus aureus in a HIV primary care clinicChristopher J Graber
J Acquir Immune Defic Syndr 49:231-3. 2008
Clinical practice: colonization, fomites, and virulence: rethinking the pathogenesis of community-associated methicillin-resistant Staphylococcus aureus infectionLoren G Miller
Division of Infectious Diseases, Harbor University of California Los Angeles, Torrance, CA, USA
Clin Infect Dis 46:752-60. 2008....
Clonal composition of Staphylococcus aureus isolates at a Brazilian university hospital: identification of international circulating lineagesAdriana Marcos Vivoni
, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
J Clin Microbiol 44:1686-91. 2006..By applying MLRFT and MLST, we found evidence for a clonal structure in MSSA isolates and detected the dissemination of MSSA clonal complexes 1, 5, 8, 30, and 45...
