Research Topics
| Gabriel S DichterSummaryAffiliation: University of North Carolina Country: USA Publications
Research Grants
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Detail Information
Publications
Functional magnetic resonance imaging of autism spectrum disordersGabriel S Dichter
Departments of Psychiatry and Psychology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Dialogues Clin Neurosci 14:319-51. 2012..These findings provide mechanistic accounts of ASD pathophysiology and suggest directions for future research aimed at elucidating etiologic models and developing rationally derived and targeted treatments...
Functional neuroimaging of treatment effects in psychiatry: methodological challenges and recommendationsGabriel S Dichter
Department of Psychiatry, University of North Carolina School of Medicine, 101 Manning Drive, Chapel Hill, NC 27599 7255, USA
Int J Neurosci 122:483-93. 2012..We review these methodological considerations and provide recommendations for best practices for each of these topics...- Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findingsGabriel S Dichter
Carolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA
J Neurodev Disord 4:19. 2012..This review concludes with methodological considerations for future research designed to more clearly probe reward-circuitry dysfunction, with the ultimate goal of improved intervention strategies... - Remitted major depression is characterized by reward network hyperactivation during reward anticipation and hypoactivation during reward outcomesGabriel S Dichter
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, United States
J Affect Disord 136:1126-34. 2012.... - Reward circuitry function in autism spectrum disordersGabriel S Dichter
Department of Psychiatry, University of North Carolina School of Medicine, CB 3366, 101 Manning Drive, Chapel Hill, NC 27599 3366, USA
Soc Cogn Affect Neurosci 7:160-72. 2012..The clinical implications of the double dissociation of reward type and temporal phase in reward circuitry function in ASD are discussed... - fMRI tracks reductions in repetitive behaviors in autism: two case studiesGabriel S Dichter
Department of Psychiatry, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599 3366, USA
Neurocase 16:307-16. 2010..These findings suggest that fMRI may elucidate potential mechanisms of action of targeted autism interventions... - Performance of children with autism spectrum disorders on the dimension-change card sort taskGabriel S Dichter
Neurodevelopmental Disorders Research Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, USA
J Autism Dev Disord 40:448-56. 2010..Furthermore, within the ASD group, poorer DCCS task performance did not predict more severe autism symptoms. Implications for the executive dysfunction theory of autism are discussed... - The effects of psychotherapy on neural responses to rewards in major depressionGabriel S Dichter
Department of Psychiatry, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina 27599 3366, USA
Biol Psychiatry 66:886-97. 2009..However, the potential for psychotherapy to normalize neurobiological responses to pleasant stimuli has not been evaluated... - Autism is characterized by dorsal anterior cingulate hyperactivation during social target detectionGabriel S Dichter
Department of Psychiatry, University of North Carolina School of Medicine, CB 3366, Chapel Hill, NC 27599 3366, USA
Soc Cogn Affect Neurosci 4:215-26. 2009..These data suggest that the dorsal anterior cingulate mediates social target detection in neurotypical individuals and is implicated in deficits of cognitive control of social information in ASD... - Generativity abilities predict communication deficits but not repetitive behaviors in Autism Spectrum DisordersGabriel S Dichter
Neurodevelopmental Disorders Research Center, School of Medicine, University of North Carolina, Chapel Hill, NC 27599 3366, USA
J Autism Dev Disord 39:1298-304. 2009..Results replicate reports of generativity deficits in ASD and suggest that impaired generativity may reflect communication deficits that are characteristic of the disorder... - Mapping social target detection with functional magnetic resonance imagingGabriel S Dichter
Department of Psychiatry, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599 7160, USA
Soc Cogn Affect Neurosci 4:59-69. 2009..Clinical cognitive neuroscience research of disorders characterized by cognitive dysfunction and impaired social processing would benefit from the use of tasks that evaluate the combined effects of deficits in these two domains... - Affective context interferes with cognitive control in unipolar depression: an fMRI investigationGabriel S Dichter
Department of Psychiatry, University of North Carolina at Chapel Hill School of Medicine, CB 3366, Chapel Hill, NC 27599 7160, United States
J Affect Disord 114:131-42. 2009..Unipolar major depressive disorder (MDD) is characterized by aberrant amygdala responses to sad stimuli and poor cognitive control, but the interactive effects of these impairments are poorly understood... - The effects of Brief Behavioral Activation Therapy for Depression on cognitive control in affective contexts: An fMRI investigationGabriel S Dichter
Department of Psychiatry, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599 7160, USA
J Affect Disord 126:236-44. 2010..Unipolar major depressive disorder (MDD) is characterized by impaired cognitive control in affective contexts, but the potential for psychotherapy to affect the neural correlates of these functions has not been evaluated... - fMRI of alterations in reward selection, anticipation, and feedback in major depressive disorderMoria J Smoski
Department of Psychiatry, Duke University Medical Center, Durham, NC, 27710, USA
J Affect Disord 118:69-78. 2009..Results indicate that MDD is characterized by striatal hyporesponsivity, and that future studies of MDD treatments that seek to improve responses to rewarding stimuli should assess striatal functioning... - Reward circuitry function in autism during face anticipation and outcomesGabriel S Dichter
Carolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill School of Medicine, 101 Manning Drive, Chapel Hill, NC 27599 3366, USA
J Autism Dev Disord 42:147-60. 2012..Additionally, atypical amygdala activation during the processing of social rewards may contribute to the development or expression of autistic features... - Neural mechanisms of subclinical depressive symptoms in women: a pilot functional brain imaging studyJennifer N Felder
Carolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599 7160, USA
BMC Psychiatry 12:152. 2012..The purpose of this study was to evaluate relations between subclinical levels of depressive symptoms and neural activation patterns during tasks previously shown to differentiate individuals with and without MDD... - Smoking withdrawal is associated with increases in brain activation during decision making and reward anticipation: a preliminary studyMerideth A Addicott
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Box 2701, Durham, NC 27708, USA
Psychopharmacology (Berl) 219:563-73. 2012..Acute nicotine abstinence is associated with disruption of executive function and reward processes; however, the neurobiological basis of these effects has not been fully elucidated... - Major depressive disorder is characterized by greater reward network activation to monetary than pleasant image rewardsMoria J Smoski
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
Psychiatry Res 194:263-70. 2011..Results suggest reduced reward network activation in MDD when anticipating rewards, as well as relatively greater hypoactivation to pleasant image than monetary rewards... - Phenomenology and measurement of circumscribed interests in autism spectrum disordersLauren M Turner-Brown
Carolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599 7255, USA
Autism 15:437-56. 2011..The present study offers further support for the notion that CI reflect a clinically significant feature of ASD that warrants intervention in some children... - Social stimuli interfere with cognitive control in autismGabriel S Dichter
Department of Psychiatry, University of North Carolina at Chapel Hill School of Medicine, CB 7160, 101 Manning Drive, Chapel Hill, NC 27599 7160, USA
Neuroimage 35:1219-30. 2007..Implications for research into cognitive control deficits in autism are discussed... - Atypical modulation of cognitive control by arousal in autismGabriel S Dichter
Department of Psychiatry and Neurodevelopmental Disorders Research Center, University of North Carolina at Chapel Hill School of Medicine, CB 3366, 101 Manning Drive, Chapel Hill, NC 27599 7160, United States
Psychiatry Res 164:185-97. 2008.... - Affective modulation of the startle eyeblink and postauricular reflexes in autism spectrum disorderGabriel S Dichter
Carolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599 7160, USA
J Autism Dev Disord 40:858-69. 2010.... 
Relations among intelligence, executive function, and P300 event related potentials in schizophreniaGabriel S Dichter
Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina 27599, USA
J Nerv Ment Dis 194:179-87. 2006..These results suggest diagnostic group differences in the association between P300 and IQ and indicate that investigations designed to explore P300-IQ relations should include measures of executive functioning in their models...- Brief report: feasibility of social cognition and interaction training for adults with high functioning autismLauren M Turner-Brown
Neurodevelopmental Disorders Research Center, University of North Carolina at Chapel Hill School of Medicine, CB 3367, UNC Chapel Hill, Chapel Hill, NC 27599 3367, USA
J Autism Dev Disord 38:1777-84. 2008..Findings indicate SCIT-A shows promise as an intervention for adults with HFA... - Unipolar depression does not moderate responses to the Sweet Taste TestGabriel S Dichter
Department of Psychiatry, Department of Psychiatry, University of North Carolina School of Medicine, 101 Manning Drive, Chapel Hill, NC 27599 3366, USA
Depress Anxiety 27:859-63. 2010..However, STT response profiles in unipolar major depressive disorder (MDD), a disorder characterized by anhedonia, have been minimally investigated... - Adults with autism spectrum disorders exhibit decreased sensitivity to reward parameters when making effort-based decisionsCara R Damiano
Department of Psychology, University of North Carolina at Chapel Hill, CB 3270, Davie Hall, UNC CH, Chapel Hill, NC, 27599 3270, USA
J Neurodev Disord 4:13. 2012..abstract:..
Research Grants
- Reward System Recovery Following Behavioral Activation Therapy in DepressionGABRIEL DICHTER; Fiscal Year: 2007..Such a strategy is consistent with NIMH's mission to reduce the burden of psychiatric disorders. ..