- Compound ranking based on a new mathematical measure of effectiveness using time course data from cell-based assaysFrancisco J Diaz
Department of Biostatistics, University of Kansas Medical Center, Mail Stop 1026, 3901 Rainbow Blvd, Kansas City, KS 66160, USA
Comb Chem High Throughput Screen 16:168-79. 2013..Our approach may also be a good alternative to computing the half maximal effective concentration (EC₅₀) in studies searching for compounds that promote cell growth...
- Drug dosage individualization based on a random-effects linear modelFrancisco J Diaz
Department of Biostatistics, University of Kansas Medical Center, Kansas City, KS 66160, USA
J Biopharm Stat 22:463-84. 2012....
- Using structural equations to test for a direct effect of some antipsychotics on triglyceride levels in drug-naïve first-episode psychosis patientsFrancisco J Diaz
Department of Biostatistics, The University of Kansas Medical Center, Kansas City, KS, USA
Schizophr Res 131:82-9. 2011..Haloperidol effects on triglyceride levels and BMI were no different from those of risperidone. In conclusion, olanzapine increased triglyceride levels without the mediation of weight gain during a one-year study in naïve patients...
- Possible effects of some antipsychotic drugs on C-reactive protein in a drug-naïve psychotic sampleFrancisco J Diaz
Department of Biostatistics, The University of Kansas Medical Center, Kansas City, KS, United States
Schizophr Res 121:207-12. 2010..009). After 12 months, only smoking was associated with increased CRP levels. Future studies need to verify that different antipsychotics may have differential effects on CRP levels, particularly after 3 months of treatment...