D M Diamond
Affiliation: University of Colorado Health Sciences Center
- The neurosteroid dehydroepiandrosterone sulfate (DHEAS) enhances hippocampal primed burst, but not long-term, potentiationD M Diamond
Department of Pharmacology, University of Colorado Health Sciences Center, Denver, USA
Neurosci Lett 202:204-8. 1996..The present findings suggest that DHEAS could enhance memory by facilitating the induction of neural plasticity...
- Psychological stress impairs spatial working memory: relevance to electrophysiological studies of hippocampal functionD M Diamond
Department of Pharmacology, University of Colorado Health Sciences Center, Denver 80262, USA
Behav Neurosci 110:661-72. 1996..Stress appears to induce a transient disruption of hippocampal function, which is revealed behaviorally as retrograde amnesia and physiologically as a blockade of synaptic plasticity...
- A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's diseaseD Morgan
Department of Pharmacology, University of South Florida, Tampa 33612, USA
Nature 408:982-5. 2000..The A beta-vaccinated mice also had a partial reduction in amyloid burden at the end of the study. This therapeutic approach may thus prevent and, possibly, treat Alzheimer's dementia...
- Correlation between cognitive deficits and Abeta deposits in transgenic APP+PS1 miceM N Gordon
Alzheimer's Research Laboratory, Department of Pharmacology, University of South Florida, 33612, Tampa, FL, USA
Neurobiol Aging 22:377-85. 2001..These data argue that radial arm water maze testing of doubly transgenic mice may be a useful behavioral endpoint in evaluating the functional consequences of potential AD therapies, especially those designed to reduce Abeta load...