Jorge Di Paola

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. ncbi Application of current knowledge to the management of bleeding events during immune tolerance induction
    J Di Paola
    Department of Pediatrics, University of Iowa, Iowa City, IA 52242, USA
    Haemophilia 12:591-7. 2006
  2. ncbi ReFacto and Advate: a single-dose, randomized, two-period crossover pharmacokinetics study in subjects with haemophilia A
    J Di Paola
    University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
    Haemophilia 13:124-30. 2007
  3. ncbi Determinants of bleeding severity in von Willebrand disease
    Jorge Di Paola
    Department of Pediatrics, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Curr Hematol Rep 4:345-9. 2005
  4. ncbi Platelet glycoprotein I(b)alpha and integrin alpha2 beta1 polymorphisms: gene frequencies and linkage disequilibrium in a population diversity panel
    J Di Paola
    Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    J Thromb Haemost 3:1511-21. 2005
  5. ncbi Product selection issues in the management of hemophilia B
    Jorge Di Paola
    Great Plains Hemophilia Treatment Center, Iowa City, Iowa, USA
    Blood Coagul Fibrinolysis 15:S17-8. 2004
  6. ncbi Breakpoint of a balanced translocation (X:14) (q27.1;q32.3) in a girl with severe hemophilia B maps proximal to the factor IX gene
    J Di Paola
    Department of Pediatrics, University of Iowa, Iowa City, IA, USA
    J Thromb Haemost 2:437-40. 2004
  7. ncbi Role of FcRgamma and factor XIIIA in coated platelet formation
    Shawn M Jobe
    Department of Pediatrics, University of Iowa College of Medicine, Iowa City, IA 52242, USA
    Blood 106:4146-51. 2005
  8. ncbi Critical role for the mitochondrial permeability transition pore and cyclophilin D in platelet activation and thrombosis
    Shawn M Jobe
    Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City, IA, USA
    Blood 111:1257-65. 2008
  9. ncbi Recombinant factor IX for clinical and research use
    Paul E Monahan
    Department of Pediatrics, Gene Therapy Center, Harold R Roberts Comprehensive Hemophilia Treatment Center, University or North Carolina at Chapel Hill, Chapel Hill, NC 27599 7236, USA
    Semin Thromb Hemost 36:498-509. 2010
  10. ncbi Tissue factor signals airway epithelial basal cell survival via coagulation and protease-activated receptor isoforms 1 and 2
    Shama Ahmad
    Department of Pediatrics, National Jewish Health, Denver, CO, USA
    Am J Respir Cell Mol Biol 48:94-104. 2013

Collaborators

Detail Information

Publications13

  1. ncbi Application of current knowledge to the management of bleeding events during immune tolerance induction
    J Di Paola
    Department of Pediatrics, University of Iowa, Iowa City, IA 52242, USA
    Haemophilia 12:591-7. 2006
    ....
  2. ncbi ReFacto and Advate: a single-dose, randomized, two-period crossover pharmacokinetics study in subjects with haemophilia A
    J Di Paola
    University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
    Haemophilia 13:124-30. 2007
    ..Results from this PKs comparison of two different rFVIII products, using chromogenic substrate assay to measure FVIII:C, showed that ReFacto and Advate are bioequivalent to each other...
  3. ncbi Determinants of bleeding severity in von Willebrand disease
    Jorge Di Paola
    Department of Pediatrics, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Curr Hematol Rep 4:345-9. 2005
    ..It is hoped that new clinical-genetic studies will shed light on these issues and help practitioners to determine the population at risk for bleeding...
  4. ncbi Platelet glycoprotein I(b)alpha and integrin alpha2 beta1 polymorphisms: gene frequencies and linkage disequilibrium in a population diversity panel
    J Di Paola
    Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    J Thromb Haemost 3:1511-21. 2005
    ..These data provide a valuable resource for optimal selection of variants best tailored for association studies of vascular disease or bleeding disorders when examining individuals of different ancestral origins...
  5. ncbi Product selection issues in the management of hemophilia B
    Jorge Di Paola
    Great Plains Hemophilia Treatment Center, Iowa City, Iowa, USA
    Blood Coagul Fibrinolysis 15:S17-8. 2004
    ..It is expected that both recombinant and plasma-derived products will continue to be used worldwide in the treatment of hemophilia B...
  6. ncbi Breakpoint of a balanced translocation (X:14) (q27.1;q32.3) in a girl with severe hemophilia B maps proximal to the factor IX gene
    J Di Paola
    Department of Pediatrics, University of Iowa, Iowa City, IA, USA
    J Thromb Haemost 2:437-40. 2004
    ..Since the FIX gene seems to be intact in the derivative 14, the breakpoint may affect an upstream regulatory sequence that subjects the gene to position effect variegation (PEV)...
  7. ncbi Role of FcRgamma and factor XIIIA in coated platelet formation
    Shawn M Jobe
    Department of Pediatrics, University of Iowa College of Medicine, Iowa City, IA 52242, USA
    Blood 106:4146-51. 2005
    ..We conclude that FcRgamma, but not factor XIIIA, is essential for formation of highly procoagulant coated platelets following dual stimulation with collagen and thrombin...
  8. ncbi Critical role for the mitochondrial permeability transition pore and cyclophilin D in platelet activation and thrombosis
    Shawn M Jobe
    Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City, IA, USA
    Blood 111:1257-65. 2008
    ..These results implicate CypD and the MPTP as critical regulators of platelet activation and suggest a novel CypD-dependent negative-feedback mechanism regulating arterial thrombosis...
  9. ncbi Recombinant factor IX for clinical and research use
    Paul E Monahan
    Department of Pediatrics, Gene Therapy Center, Harold R Roberts Comprehensive Hemophilia Treatment Center, University or North Carolina at Chapel Hill, Chapel Hill, NC 27599 7236, USA
    Semin Thromb Hemost 36:498-509. 2010
    ..The experience with the existing recombinant FIX product is reviewed with a focus on the novel products and the potential to improve the quality of life for individuals with hemophilia B...
  10. ncbi Tissue factor signals airway epithelial basal cell survival via coagulation and protease-activated receptor isoforms 1 and 2
    Shama Ahmad
    Department of Pediatrics, National Jewish Health, Denver, CO, USA
    Am J Respir Cell Mol Biol 48:94-104. 2013
    ..The implications of these findings are discussed in the context of basal cell-associated TF activity in normal and injured tissues and of the potential for repair of airway epithelium in lung disease...
  11. ncbi Making a diagnosis of VWD
    Brian R Branchford
    Department of Pediatrics, Section of Hematology Oncology Bone Marrow Transplantation, University of Colorado Anschutz Medical Campus, Aurora, CO, USA
    Hematology Am Soc Hematol Educ Program 2012:161-7. 2012
    ..Finally, common testing pitfalls and diagnostic dilemmas are covered, including the challenge created by the overlap of borderline low VWF levels and mild bleeding...
  12. ncbi New developments in the treatment of pediatric hemophilia and bleeding disorders
    Brian R Branchford
    Department of Pediatrics, Section of Hematology Oncology Bone Marrow Transplantation, Children s Hospital Colorado, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045, USA
    Curr Opin Pediatr 25:23-30. 2013
    ..Because of the limitations of current treatment options, novel therapies are being developed, many of which are reviewed here...
  13. ncbi Role of the adapter protein SLP-76 in GPVI-dependent platelet procoagulant responses to collagen
    Lorie Leo
    Departments of Internal Medicine and Pediatrics, University of Iowa College of Medicine, and Veterans Affairs Medical Center, Iowa City, IA 52242, USA
    Blood 100:2839-44. 2002
    ..Thus, both GPVI-dependent and GPVI-independent pathways contribute to collagen-induced platelet procoagulant activity...