Anuradha Dhingra

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. pmc Gβ3 is required for normal light ON responses and synaptic maintenance
    Anuradha Dhingra
    Department of Neuroscience, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Neurosci 32:11343-55. 2012
  2. pmc Autoantibodies in melanoma-associated retinopathy target TRPM1 cation channels of retinal ON bipolar cells
    Anuradha Dhingra
    Department of Neuroscience, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Neurosci 31:3962-7. 2011
  3. pmc Kir2.4 surface expression and basal current are affected by heterotrimeric G-proteins
    Pyroja Sulaiman
    Department of Neuroscience, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Biol Chem 288:7420-9. 2013
  4. pmc mGluR6 transcripts in non-neuronal tissues
    Tamar Vardi
    Department of Neuroscience, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Histochem Cytochem 59:1076-86. 2011
  5. doi request reprint Cones respond to light in the absence of transducin β subunit
    Sergei S Nikonov
    Departments of Neuroscience and Ophthalmology, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Neurosci 33:5182-94. 2013
  6. ncbi request reprint A retinal-specific regulator of G-protein signaling interacts with Galpha(o) and accelerates an expressed metabotropic glutamate receptor 6 cascade
    Anuradha Dhingra
    Department of Neuroscience, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6058, USA
    J Neurosci 24:5684-93. 2004
  7. ncbi request reprint Neurochemical organization of the first visual synapse
    Noga Vardi
    Department of Neuroscience, University of Pennsylvania, PA 19104, USA
    Keio J Med 51:154-64. 2002
  8. pmc Probing neurochemical structure and function of retinal ON bipolar cells with a transgenic mouse
    Anuradha Dhingra
    Department of Neuroscience, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6058, USA
    J Comp Neurol 510:484-96. 2008
  9. ncbi request reprint Light response of retinal ON bipolar cells requires a specific splice variant of Galpha(o)
    Anuradha Dhingra
    Department of Neuroscience, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Neurosci 22:4878-84. 2002

Collaborators

Detail Information

Publications9

  1. pmc Gβ3 is required for normal light ON responses and synaptic maintenance
    Anuradha Dhingra
    Department of Neuroscience, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Neurosci 32:11343-55. 2012
    ..Furthermore, Gβ(3) may play a role in synaptic maintenance since in its absence, the number of invaginating rod bipolar dendrites is greatly reduced, a deficit that was not observed at 3 weeks, the end of the developmental period...
  2. pmc Autoantibodies in melanoma-associated retinopathy target TRPM1 cation channels of retinal ON bipolar cells
    Anuradha Dhingra
    Department of Neuroscience, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Neurosci 31:3962-7. 2011
    ..We conclude that the vision of at least some patients with MAR is compromised due to autoantibody-mediated inactivation of the TRPM1 channel...
  3. pmc Kir2.4 surface expression and basal current are affected by heterotrimeric G-proteins
    Pyroja Sulaiman
    Department of Neuroscience, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Biol Chem 288:7420-9. 2013
    ..Moreover, we show that in retinal ON bipolar cells lacking Gβ3, localization of Kir2.4 in the dendritic tips is reduced. We conclude that Gβγ targets Kir2.4 to the plasma membrane, and Gαo slows this down by binding Gβγ...
  4. pmc mGluR6 transcripts in non-neuronal tissues
    Tamar Vardi
    Department of Neuroscience, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Histochem Cytochem 59:1076-86. 2011
    ..Furthermore, calcium imaging with Fura-2 showed that application of L-AP4, an agonist for group III metabotropic glutamate receptors including mGluR6, elevated calcium in endothelial cells...
  5. doi request reprint Cones respond to light in the absence of transducin β subunit
    Sergei S Nikonov
    Departments of Neuroscience and Ophthalmology, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Neurosci 33:5182-94. 2013
    ..These results suggest that the main role of Gβ3 in cones is to establish optimal levels of transducin heteromer in the outer segment, thereby indirectly contributing to robust response properties...
  6. ncbi request reprint A retinal-specific regulator of G-protein signaling interacts with Galpha(o) and accelerates an expressed metabotropic glutamate receptor 6 cascade
    Anuradha Dhingra
    Department of Neuroscience, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6058, USA
    J Neurosci 24:5684-93. 2004
    ..This would tend to match its kinetics to that of the OFF bipolar that arises directly from ligand-gated channels...
  7. ncbi request reprint Neurochemical organization of the first visual synapse
    Noga Vardi
    Department of Neuroscience, University of Pennsylvania, PA 19104, USA
    Keio J Med 51:154-64. 2002
    ..In this talk/review we describe the structures and the neurochemicals involved in transmitting the visual signal at this synaptic complex...
  8. pmc Probing neurochemical structure and function of retinal ON bipolar cells with a transgenic mouse
    Anuradha Dhingra
    Department of Neuroscience, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6058, USA
    J Comp Neurol 510:484-96. 2008
    ..The channels and modulators found in ON bipolar cells likely shape their light response. Additional uses of the Grm6-GFP mouse are also discussed...
  9. ncbi request reprint Light response of retinal ON bipolar cells requires a specific splice variant of Galpha(o)
    Anuradha Dhingra
    Department of Neuroscience, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Neurosci 22:4878-84. 2002
    ..Thus, the light response of the ON bipolar cell is probably carried by its strongly expressed splice variant, Galpha(o1)...