- Y-box binding protein 1 and RNase UK114 mediate monocyte chemoattractant protein 1 mRNA stability in vascular smooth muscle cellsLatika Dhawan
Aab Cardiovascular Research Institute and Department of Medicine, University of Rochester, Rochester, New York, USA
Mol Cell Biol 32:3768-75. 2012..UK did not degrade MCP-1 mRNA; however, upon addition to nondegrading control extracts, it rapidly degraded MCP-1 mRNA. These studies define new roles for GR, YB-1, and UK in the formation of a molecular complex that degrades MCP-1 mRNA...
- A novel role for the glucocorticoid receptor in the regulation of monocyte chemoattractant protein-1 mRNA stabilityLatika Dhawan
Cardiovascular Research Institute, University of Rochester, Rochester, New York 14620, USA
J Biol Chem 282:10146-52. 2007..These data suggest a novel role for the GR in binding to and facilitating mRNA degradation. These results provide novel insights into GR function and may provide a new approach to attenuate the inflammatory response mediated by MCP-1...
- Protein kinase Cδ mediates MCP-1 mRNA stabilization in vascular smooth muscle cellsBin Liu
Department of Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA
Mol Cell Biochem 344:73-9. 2010..This study identifies a novel role for PKCδ in mediating mRNA stability in smooth muscle cells...