V Dharnidharka

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. ncbi request reprint Post-transplant lymphoproliferative disorder in the United States: young Caucasian males are at highest risk
    Vikas R Dharnidharka
    Division of Pediatric Nephrology, University of Florida College of Medicine, Gainesville, FL, USA
    Am J Transplant 2:993-8. 2002
  2. doi request reprint Recombinant growth hormone use pretransplant and risk for post-transplant lymphoproliferative disease--a report of the NAPRTCS
    Vikas R Dharnidharka
    Division of Pediatric Nephrology, University of Florida College of Medicine, Gainesville, FL 32610 0296, USA
    Pediatr Transplant 12:689-95. 2008
  3. ncbi request reprint Post-transplant lymphoproliferative disease
    Vikas R Dharnidharka
    Division of Pediatric Nephrology, University of Florida College of Medicine, PO Box 100296, 1600 SW Archer Road, Gainesville, FL 32610 0296, USA
    Pediatr Nephrol 24:731-6. 2009
  4. ncbi request reprint Hodgkin's lymphoma after post-transplant lymphoproliferative disease in a renal transplant recipient
    Vikas R Dharnidharka
    Department of Pediatrics, Division of Pediatric Nephrology, University of Florida College of Medicine, 1600 SW Archer Road, Gainesville, FL 32610 0296, USA
    Pediatr Transplant 8:87-90. 2004
  5. pmc Immune biomarker panel monitoring utilizing IDO enzyme activity and CD4 ATP levels: prediction of acute rejection vs. viral replication events
    Vikas R Dharnidharka
    Division of Pediatric Nephrology, University of Florida College of Medicine, Gainesville, FL 32610 0296, USA
    Pediatr Transplant 15:321-8. 2011
  6. ncbi request reprint Infected kidney cysts
    V R Dharnidharka
    Department of Pediatrics, University of Florida, PO Box 100296, Gainesville, FL 32610, USA
    Kidney Int 69:783. 2006
  7. ncbi request reprint Pediatric kidney transplantation literature review 2006
    Vikas R Dharnidharka
    Division of Pediatric Nephrology, University of Florida College of Medicine, Gainesville, FL, USA
    Pediatr Transplant 11:354-65. 2007
  8. ncbi request reprint En-bloc kidney transplantation in the United states: an analysis of united network of organ sharing (UNOS) data from 1987 to 2003
    Vikas R Dharnidharka
    Department of Pediatrics, University of Florida College of Medicine, Gainesville, USA
    Am J Transplant 5:1513-7. 2005
  9. ncbi request reprint Post-transplant lymphoproliferative disease: association with induction therapy?
    Vikas R Dharnidharka
    University of Florida College of Medicine, Gainesville, Florida 32610 0296, USA
    Drugs 66:429-38. 2006
  10. doi request reprint Assessing the value of ureteral stent placement in pediatric kidney transplant recipients
    Vikas R Dharnidharka
    Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, USA
    Transplantation 85:986-91. 2008

Detail Information

Publications43

  1. ncbi request reprint Post-transplant lymphoproliferative disorder in the United States: young Caucasian males are at highest risk
    Vikas R Dharnidharka
    Division of Pediatric Nephrology, University of Florida College of Medicine, Gainesville, FL, USA
    Am J Transplant 2:993-8. 2002
    ..The PTLD incidence per year and incidence density have increased in recent years. Young Caucasian males are at highest risk for PTLD development among solid-organ-transplant recipients. The incidence of PTLD is increasing...
  2. doi request reprint Recombinant growth hormone use pretransplant and risk for post-transplant lymphoproliferative disease--a report of the NAPRTCS
    Vikas R Dharnidharka
    Division of Pediatric Nephrology, University of Florida College of Medicine, Gainesville, FL 32610 0296, USA
    Pediatr Transplant 12:689-95. 2008
    ..88, 95% CI = 1.00-3.55, p = 0.05). In contrast, use of rhGH during dialysis or post-transplant only was not associated with a higher risk for PTLD. Continued monitoring is recommended...
  3. ncbi request reprint Post-transplant lymphoproliferative disease
    Vikas R Dharnidharka
    Division of Pediatric Nephrology, University of Florida College of Medicine, PO Box 100296, 1600 SW Archer Road, Gainesville, FL 32610 0296, USA
    Pediatr Nephrol 24:731-6. 2009
    ..PTLD remains a risk factor for graft loss, though re-transplants have not, to date, been associated with repeat PTLD...
  4. ncbi request reprint Hodgkin's lymphoma after post-transplant lymphoproliferative disease in a renal transplant recipient
    Vikas R Dharnidharka
    Department of Pediatrics, Division of Pediatric Nephrology, University of Florida College of Medicine, 1600 SW Archer Road, Gainesville, FL 32610 0296, USA
    Pediatr Transplant 8:87-90. 2004
    ..True HL following PTLD has been reported in only three previous cases, with good response to standard chemotherapy in each...
  5. pmc Immune biomarker panel monitoring utilizing IDO enzyme activity and CD4 ATP levels: prediction of acute rejection vs. viral replication events
    Vikas R Dharnidharka
    Division of Pediatric Nephrology, University of Florida College of Medicine, Gainesville, FL 32610 0296, USA
    Pediatr Transplant 15:321-8. 2011
    ..01) and blood CD4-ATP levels showed a decrease (p = 0.007) prior to a major infection event. These pilot results suggest that a panel of biomarkers together can predict over- or under-immunosuppression, but need independent validation...
  6. ncbi request reprint Infected kidney cysts
    V R Dharnidharka
    Department of Pediatrics, University of Florida, PO Box 100296, Gainesville, FL 32610, USA
    Kidney Int 69:783. 2006
  7. ncbi request reprint Pediatric kidney transplantation literature review 2006
    Vikas R Dharnidharka
    Division of Pediatric Nephrology, University of Florida College of Medicine, Gainesville, FL, USA
    Pediatr Transplant 11:354-65. 2007
    ..This review is meant to be comprehensive but not exhaustive...
  8. ncbi request reprint En-bloc kidney transplantation in the United states: an analysis of united network of organ sharing (UNOS) data from 1987 to 2003
    Vikas R Dharnidharka
    Department of Pediatrics, University of Florida College of Medicine, Gainesville, USA
    Am J Transplant 5:1513-7. 2005
    ..9% versus 23.4%, p < 0.001). National registry data suggest that EBK transplants present a viable option for transplantation of very young donor kidneys...
  9. ncbi request reprint Post-transplant lymphoproliferative disease: association with induction therapy?
    Vikas R Dharnidharka
    University of Florida College of Medicine, Gainesville, Florida 32610 0296, USA
    Drugs 66:429-38. 2006
    ..While some studies suggest an increased risk of PTLD after induction antibody use, other studies do not; the available data are not conclusive either way at this time...
  10. doi request reprint Assessing the value of ureteral stent placement in pediatric kidney transplant recipients
    Vikas R Dharnidharka
    Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, USA
    Transplantation 85:986-91. 2008
    ..However, stent placement may also increase risk for early urinary tract infection (early UTI; <3 months after transplant) and BK virus allograft nephropathy (BKVAN). In children, the usefulness of stent placement is not well defined...
  11. doi request reprint An OPTN analysis of national registry data on treatment of BK virus allograft nephropathy in the United States
    Vikas R Dharnidharka
    Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, USA
    Transplantation 87:1019-26. 2009
    ..This study determined the rates of TBKV within 24 months posttransplant time and elucidated the risk factors for TBKV from this multicenter database...
  12. ncbi request reprint Mycophenolate, tacrolimus and post-transplant lymphoproliferative disorder: a report of the North American Pediatric Renal Transplant Cooperative Study
    Vikas R Dharnidharka
    Division of Pediatric Nephrology, University of Florida College of Medicine, Gainesville, Florida, USA
    Pediatr Transplant 6:396-9. 2002
    ..28, p = 0.692). There have been no cases of PTLD in 197 patients who received both FK506 and MMF at day 30. We conclude that FK506 and MMF use are not currently associated with increased risk of PTLD in pediatric kidney transplants...
  13. ncbi request reprint Pulmonary dysplasia, Denys-Drash syndrome and Wilms tumor 1 gene mutation in twins
    V R Dharnidharka
    Department of Pediatric Medicine, Children s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Pediatr Nephrol 16:227-31. 2001
    ..We propose that this WT1 gene mutation contributes to both DMS and developmental pulmonary abnormalities by altering ME interactions in both organs...
  14. ncbi request reprint Risk factors for posttransplant lymphoproliferative disorder (PTLD) in pediatric kidney transplantation: a report of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS)
    V R Dharnidharka
    Division of Pediatric Nephrology, University of Florida Health Science Center, Gainesville, USA
    Transplantation 71:1065-8. 2001
    ..The North American Pediatric Renal Transplant Cooperative Study (NAPRTCS) database has documented 56 cases of PTLD, the largest such series to date...
  15. ncbi request reprint Management of pediatric postrenal transplantation infections
    V R Dharnidharka
    Division of Pediatric Nephrology, University of Florida College of Medicine, Gainesville, FL, USA
    Semin Nephrol 21:521-31. 2001
    ..It is hoped that the use of more specific immunosuppressive agents that block only the alloactivated T cells and leave the rest of the immune response intact may result in a reduction in the number and frequency of infections...
  16. doi request reprint Improved survival with recent Post-Transplant Lymphoproliferative Disorder (PTLD) in children with kidney transplants
    V R Dharnidharka
    University of Florida and Shands Children s Hospital, Gainesville, FL, USA
    Am J Transplant 11:751-8. 2011
    ..86, p < 0.001), and with worse survival were late PTLD (AHR 1.98, p = 0.0176) and patient age above 13 at PTLD (AHR 3.43, p value 0.022). In children with kidney transplants, patient survival has improved with more recent PTLDs...
  17. ncbi request reprint Risk for post-transplant lymphoproliferative disorder after polyclonal antibody induction in kidney transplantation
    Vikas R Dharnidharka
    Division of Pediatric Nephrology, University of Florida Coillege of Medicine, Gainesville, FL 32610 0296, USA
    Pediatr Transplant 9:622-6. 2005
    ..There is a higher aRR for PTLD after kidney transplantation with E-ATG, but not R-ATG. This may only partially be explained by shorter follow up time and may represent differential hazard for PTLD among the agents...
  18. ncbi request reprint Serum cystatin C is superior to serum creatinine as a marker of kidney function: a meta-analysis
    Vikas R Dharnidharka
    Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL 32610 0296, USA
    Am J Kidney Dis 40:221-6. 2002
    ..However, there are conflicting reports regarding the superiority of Cys C over serum creatinine (Cr), with a few studies suggesting no significant difference...
  19. doi request reprint The BK virus in renal transplant recipients-review of pathogenesis, diagnosis, and treatment
    Vikas R Dharnidharka
    Division of Pediatric Nephrology, University of Florida College of Medicine and Shands Children s Hospital, 1600 SW Archer Road, PO Box 100296 HD 214, Gainesville, FL 32610 0296, USA
    Pediatr Nephrol 26:1763-74. 2011
    ..Similarities and differences between cytomegalovirus, Epstein-Barr virus, and BV virus, the three major viral infections in kidney transplantation, are highlighted...
  20. doi request reprint Retransplantation after BK virus nephropathy in prior kidney transplant: an OPTN database analysis
    V R Dharnidharka
    Department of Pediatrics, University of Florida College of Medicine, Shands Children s Hospital, Gainesville, FL, USA
    Am J Transplant 10:1312-5. 2010
    ..5%, 93.6%, 65.5 and 68.4 mL/min, respectively. Retransplantation after BKV appears to be associated with good results...
  21. ncbi request reprint Renal transplantation: the present and the future
    Vikas R Dharnidharka
    Division of Pediatric Nephrology, University of Florida College of Medicine, Gainesville, FL, USA
    Indian J Pediatr 72:785-8. 2005
    ..Newer technologies such as stem cell transplantation, tissue engineering and xenotransplantation promise even more changes in the future...
  22. ncbi request reprint Risk factors for hospitalization for bacterial or viral infection in renal transplant recipients--an analysis of USRDS data
    V R Dharnidharka
    Division of Pediatric Nephrology, University of Florida College of Medicine, Gainesville, FL, USA
    Am J Transplant 7:653-61. 2007
    ..53, 2.12); (iv) female gender AHR 1.63, 95% CI = 1.41, 1.88). Lower AHR for HVI was seen in CMV-positive recipients and for HBI with more recent year of transplant. Other covariates did not impact significantly in either HVI or HBI...
  23. doi request reprint Low viral load post-transplant lymphoproliferative disease localized within the tongue
    D D Henry
    Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL 32610 0296, USA
    Transpl Infect Dis 10:426-30. 2008
    ..3 mg/dL. Unusual localization of PTLD to areas in non-lymphoid tissue without regional lymphoid involvement may result in misleading low peripheral blood EBV viral loads...
  24. ncbi request reprint Ciprofloxacin overdose: acute renal failure with prominent apoptotic changes
    V R Dharnidharka
    Division of Nephrology, Children s Hospital, Boston, MA 02115, USA
    Am J Kidney Dis 31:710-2. 1998
    ..This report shows that the distal nephron can be singularly involved in acute renal failure and that electron microscopy or plastic-embedded sections may be necessary to define its involvement...
  25. ncbi request reprint Fas stimulation results in selective islet infiltrate apoptosis in situ and reversal of diabetes
    Vikas R Dharnidharka
    Departments of Pediatrics and Pathology, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    Ann N Y Acad Sci 958:160-2. 2002
    ..Administration of the Fas agonist immediately after onset of diabetes led to reversal of diabetes in NOD mice. Inducing peripheral T cell apoptosis may be a potential method for reversal of autoimmune diabetes...
  26. ncbi request reprint Cat scratch disease and acute rejection after pediatric renal transplantation
    Vikas R Dharnidharka
    The Division of Pediatric Nephrology, Shands Children s Hospital and University of Florida College of Medicine, Gainesville, Florida 32610, USA
    Pediatr Transplant 6:327-31. 2002
    ..Acute rejection following CSD has not been previously reported. CSD should be included in the differential diagnosis of fever in the post-transplant setting, especially where PTLD is suspected...
  27. ncbi request reprint Extracorporeal removal of toxic valproic acid levels in children
    Vikas R Dharnidharka
    Division of Pediatric Nephrology, Shands Children s Hospital and University of Florida College of Medicine, P O Box 100296, 1600 SW Archer Road, Gainesville FL 32610 0296, USA
    Pediatr Nephrol 17:312-5. 2002
    ..9 h after dialysis. Both conventional hemodialysis and high-flux hemodiafiltration are effective treatment modalities that should be offered to all pediatric patients with valproic acid ingestion and neurological compromise...
  28. ncbi request reprint Nephrogenic fibrosing dermopathy in pediatric patients
    Sima M Jain
    Division of Dermatology, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA
    Pediatr Nephrol 19:467-70. 2004
    ..Since both our patients also had previously experienced large vessel thrombosis, hypercoagulable states may also be implicated...
  29. ncbi request reprint Effects of urinary tract infection on outcomes after renal transplantation in children
    Vikas R Dharnidharka
    Division of Pediatric Nephrology, University of Florida Health Science Center, Gainesville, FL 32610 0296, USA
    Clin J Am Soc Nephrol 2:100-6. 2007
    ..In girls, only those in the youngest age category (0 to 1) had higher risk for UTI. Children are at greater risk for graft loss after early but not necessarily late UTI. UTI was not an independent predictor of death in this population...
  30. ncbi request reprint Sirolimus in pediatric solid organ transplantation
    Vikas R Dharnidharka
    Pediatr Transplant 9:427-9. 2005
  31. ncbi request reprint Costimulation blockade with belatacept in renal transplantation
    Vikas R Dharnidharka
    N Engl J Med 353:2085-6; author reply 2085-6. 2005
  32. ncbi request reprint Infection frequency and profile in different age groups of kidney transplant recipients
    Vikas R Dharnidharka
    Division of Pediatric Nephrology, University of Florida College of Medicine, Gainesville FL 32610 0296, USA
    Transplantation 81:1662-7. 2006
    ....
  33. ncbi request reprint Acute-onset hearing loss with renal failure: differential diagnosis
    Carlos E Araya
    Division of Pediatric Nephrology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, USA
    Am J Kidney Dis 47:553-8. 2006
  34. ncbi request reprint Hodgkin's-like PTLD versus true Hodgkin's disease
    Vikas R Dharnidharka
    Pediatr Transplant 8:581-2. 2004
  35. ncbi request reprint Isolated idiopathic hypomagnesemia presenting as aphasia and seizures
    Vikas R Dharnidharka
    Division of Pediatric Nephrology, University of Florida College of Medicine, Gainesville, FL 32610 0296, USA
    Pediatr Neurol 33:61-5. 2005
    ..In the present case, neuronal depolarization may have been localized to language areas in the temporal lobes...
  36. ncbi request reprint Prolonged neuromuscular block due to cholinesterase depletion by plasmapheresis
    Bhiken Naik
    Department of Anesthesiology, University of Florida College of Medicine, Gainesville, FL 32610, USA
    J Clin Anesth 14:381-4. 2002
    ..Anesthesiologists should be aware of plasmapheresis as a mechanism for plasma cholinesterase depletion when using neuromuscular blocking drugs that are metabolized by this enzyme...
  37. ncbi request reprint Intermediate-dose cidofovir without probenecid in the treatment of BK virus allograft nephropathy
    Carlos E Araya
    Division of Pediatric Nephrology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL 32610 0296, USA
    Pediatr Transplant 10:32-7. 2006
    ..In our experience, intermediate-dose cidofovir without probenecid, used judiciously, is not associated with additional nephrotoxicity and may provide an additional alternative for treatment...
  38. ncbi request reprint Transient proximal tubular renal injury following Ecstasy ingestion
    Charles Kwon
    Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, USA
    Pediatr Nephrol 18:820-2. 2003
    ..To our knowledge, this is the first example of an acute and transient proximal tubular injury with Ecstasy ingestion. This complication may become more apparent with increasing use of this drug...
  39. ncbi request reprint Utility of renal imaging in the diagnostic evaluation of obese childhood primary hypertension
    Sanjeev Y Tuli
    Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida 32610 0296, USA
    Clin Pediatr (Phila) 44:589-92. 2005
    ..Larger studies may confirm that the evaluation of CP-HTN in older obese children could be similar to guidelines for evaluation of adult-HTN...
  40. ncbi request reprint Post-transplant infections now exceed acute rejection as cause for hospitalization: a report of the NAPRTCS
    Vikas R Dharnidharka
    Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, USA
    Am J Transplant 4:384-9. 2004
    ..001 for trend by transplant year). We conclude that the causes of hospitalization at all times up to 24 months post-transplant, including the critical early 6 months, have shifted away from AR to PTI...
  41. ncbi request reprint BK virus nephropathy in pediatric renal transplant recipients: an analysis of the North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS) registry
    Jodi M Smith
    Division of Nephrology, Children s Hospital and Regional Medical Center, University of Washington, 4800 Sand Point Way NE, M1 5, Seattle, WA 98105, USA
    Clin J Am Soc Nephrol 2:1037-42. 2007
    ..The objective of this study was to evaluate cases of BK virus nephropathy in the North American Pediatric Renal Trials and Collaborative Studies database...
  42. ncbi request reprint Hemodialysis catheter-related bacteremia in children: increasing antibiotic resistance and changing bacteriological profile
    Carlos E Araya
    Division of Pediatric Nephrology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL 32610 0296, USA
    Am J Kidney Dis 50:119-23. 2007
    ..We determined whether the rate of positive blood culture results per tunneled catheter-days, the spectrum of bacterial isolates, and their antibiotic susceptibility changed over time in our pediatric dialysis unit...
  43. ncbi request reprint TNP-470, an angiogenesis inhibitor, attenuates the development of allograft vasculopathy
    Mark D Denton
    Division of Nephrology, Department of Medicine, Children s Hospital, 300 Longwood Avenue, Boston, MA 02115, USA
    Transplantation 78:1218-21. 2004
    ..08+/-0.11). Therefore, TNP-470 interrupts the progression of CAV when given late but does not prevent its development when given immediately posttransplantation...