Rajiv Dhand

Summary

Affiliation: University of Missouri
Country: USA

Publications

  1. ncbi request reprint Nebulizers that use a vibrating mesh or plate with multiple apertures to generate aerosol
    Rajiv Dhand
    Division of Pulmonary, Critical Care, and Environmental Medicine, University of Missouri Columbia, Columbia, MO 65212, USA
    Respir Care 47:1406-16; discussion 1416-8. 2002
  2. ncbi request reprint Effective inhaled drug administration to mechanically ventilated patients
    Rajiv Dhand
    University of Missouri Columbia, Division of Pulmonary, Critical Care and Environmental Medicine, MA 421 Health Sciences Center DC043 00 1 Hospital Drive, Columbia, MO 65212, USA
    Expert Opin Drug Deliv 4:47-61. 2007
  3. doi request reprint How best to deliver aerosol medications to mechanically ventilated patients
    Rajiv Dhand
    Division of Pulmonary, Critical Care, and Environmental Medicine, University of Missouri, MA 421 Health Sciences Center, 1 Hospital Drive, Columbia, MO 65212, USA
    Clin Chest Med 29:277-96, vi. 2008
  4. pmc Alveolar fractal box dimension inversely correlates with mean linear intercept in mice with elastase-induced emphysema
    Mary P Andersen
    Division of Pulmonary, Critical Care, and Environmental Medicine, Department of Internal Medicine, University of Missouri, USA
    Int J Chron Obstruct Pulmon Dis 7:235-43. 2012
  5. doi request reprint Aerosol therapy in patients receiving noninvasive positive pressure ventilation
    Rajiv Dhand
    Division of Pulmonary, Critical Care, and Environmental Medicine, Department of Internal Medicine, University of Missouri, Columbia, Missouri 65212, USA
    J Aerosol Med Pulm Drug Deliv 25:63-78. 2012
  6. doi request reprint The role of nebulized therapy in the management of COPD: evidence and recommendations
    Rajiv Dhand
    University of Missouri School of Medicine, Division of Pulmonary, Critical Care, and Environmental Medicine, Columbia, USA
    COPD 9:58-72. 2012
  7. ncbi request reprint Good sleep, bad sleep! The role of daytime naps in healthy adults
    Rajiv Dhand
    Harry S Truman VA Hospital, Columbia, Missouri, USA
    Curr Opin Pulm Med 12:379-82. 2006
  8. ncbi request reprint Inhalation therapy in invasive and noninvasive mechanical ventilation
    Rajiv Dhand
    Division of Pulmonary, Critical Care and Environmental Medicine, Department of Internal Medicine, University of Missouri, Columbia, Missouri 65212, USA
    Curr Opin Crit Care 13:27-38. 2007
  9. ncbi request reprint The role of aerosolized antimicrobials in the treatment of ventilator-associated pneumonia
    Rajiv Dhand
    Division of Pulmonary, Critical Care, and Environmental Medicine, MA 421 Health Sciences Center, DC043 00, 1 Hospital Drive, University of Missouri Columbia, Columbia MO 65212, USA
    Respir Care 52:866-84. 2007
  10. ncbi request reprint Pulmonary Drug Delivery System for inhalation therapy in mechanically ventilated patients
    Rajiv Dhand
    Division of Pulmonary, Critical Care, and Environmental Medicine, MA 421 Health Sciences Center, University of Missouri Columbia, Columbia, MO 65212, USA
    Expert Rev Med Devices 5:9-18. 2008

Detail Information

Publications33

  1. ncbi request reprint Nebulizers that use a vibrating mesh or plate with multiple apertures to generate aerosol
    Rajiv Dhand
    Division of Pulmonary, Critical Care, and Environmental Medicine, University of Missouri Columbia, Columbia, MO 65212, USA
    Respir Care 47:1406-16; discussion 1416-8. 2002
    ..With these devices clinicians will be able to precisely control drug delivery to the respiratory tract...
  2. ncbi request reprint Effective inhaled drug administration to mechanically ventilated patients
    Rajiv Dhand
    University of Missouri Columbia, Division of Pulmonary, Critical Care and Environmental Medicine, MA 421 Health Sciences Center DC043 00 1 Hospital Drive, Columbia, MO 65212, USA
    Expert Opin Drug Deliv 4:47-61. 2007
    ..Improvements in drug formulations and the design and efficiency of aerosol generating devices have led to increasing application of inhaled therapies in mechanically ventilated patients...
  3. doi request reprint How best to deliver aerosol medications to mechanically ventilated patients
    Rajiv Dhand
    Division of Pulmonary, Critical Care, and Environmental Medicine, University of Missouri, MA 421 Health Sciences Center, 1 Hospital Drive, Columbia, MO 65212, USA
    Clin Chest Med 29:277-96, vi. 2008
    ..When optimal techniques of administration are employed, the efficiency of aerosolized drug delivery in mechanically ventilated patients is comparable to that achieved in ambulatory patients...
  4. pmc Alveolar fractal box dimension inversely correlates with mean linear intercept in mice with elastase-induced emphysema
    Mary P Andersen
    Division of Pulmonary, Critical Care, and Environmental Medicine, Department of Internal Medicine, University of Missouri, USA
    Int J Chron Obstruct Pulmon Dis 7:235-43. 2012
    ..A widely applicable model of emphysema that allows efficient and sensitive quantification of injury is needed to compare potential therapies...
  5. doi request reprint Aerosol therapy in patients receiving noninvasive positive pressure ventilation
    Rajiv Dhand
    Division of Pulmonary, Critical Care, and Environmental Medicine, Department of Internal Medicine, University of Missouri, Columbia, Missouri 65212, USA
    J Aerosol Med Pulm Drug Deliv 25:63-78. 2012
    ..Further research into novel delivery methods, such as the use of NIPPV with nasal cannulae, could enhance the efficiency, ease of use, and reproducibility of inhalation therapy during noninvasive ventilation...
  6. doi request reprint The role of nebulized therapy in the management of COPD: evidence and recommendations
    Rajiv Dhand
    University of Missouri School of Medicine, Division of Pulmonary, Critical Care, and Environmental Medicine, Columbia, USA
    COPD 9:58-72. 2012
    ..The impact of maintenance nebulizer treatment on other relevant clinical outcomes in patients with COPD, especially the progressive decline in lung function and frequency of exacerbations, needs further investigation...
  7. ncbi request reprint Good sleep, bad sleep! The role of daytime naps in healthy adults
    Rajiv Dhand
    Harry S Truman VA Hospital, Columbia, Missouri, USA
    Curr Opin Pulm Med 12:379-82. 2006
    ..Individuals of all age groups, from infants to the elderly, indulge in an afternoon nap. This review examines the benefits and drawbacks of daytime naps in healthy adults...
  8. ncbi request reprint Inhalation therapy in invasive and noninvasive mechanical ventilation
    Rajiv Dhand
    Division of Pulmonary, Critical Care and Environmental Medicine, Department of Internal Medicine, University of Missouri, Columbia, Missouri 65212, USA
    Curr Opin Crit Care 13:27-38. 2007
    ..Clinical use of various inhaled therapies in patients receiving invasive and noninvasive mechanical ventilation is also discussed...
  9. ncbi request reprint The role of aerosolized antimicrobials in the treatment of ventilator-associated pneumonia
    Rajiv Dhand
    Division of Pulmonary, Critical Care, and Environmental Medicine, MA 421 Health Sciences Center, DC043 00, 1 Hospital Drive, University of Missouri Columbia, Columbia MO 65212, USA
    Respir Care 52:866-84. 2007
    ..Further research is needed to support the use of inhaled antimicrobial therapy in patients with VAP...
  10. ncbi request reprint Pulmonary Drug Delivery System for inhalation therapy in mechanically ventilated patients
    Rajiv Dhand
    Division of Pulmonary, Critical Care, and Environmental Medicine, MA 421 Health Sciences Center, University of Missouri Columbia, Columbia, MO 65212, USA
    Expert Rev Med Devices 5:9-18. 2008
    ..The PDDS Clinical delivers a high percentage of the nominal dose to the lower respiratory tract, and is well suited for inhalation therapy in mechanically ventilated patients...
  11. doi request reprint Aerosol delivery during mechanical ventilation: from basic techniques to new devices
    Rajiv Dhand
    Division of Pulmonary, Critical Care, and Environmental Medicine, Department of Internal Medicine, University of Missouri Columbia, Columbia, MO 65212, USA
    J Aerosol Med Pulm Drug Deliv 21:45-60. 2008
    ..With an optimal technique of administration the efficiency of aerosol delivery during mechanical ventilation is similar to that achieved during spontaneous breathing. Further research is needed to optimize aerosol delivery during NPPV...
  12. ncbi request reprint Sleep disorders: diagnosis and treatment
    Rajiv Dhand
    Division of Pulmonary, Critical Care, and Environmental Medicine, Columbia, MO 65212, USA
    Respir Care 55:1389-96. 2010
    ..do gender differences affect the incidence, morbidity, and outcomes of sleep apnea? What are the needs of special populations with sleep disorders, such as children, patients with mental impairment, psychiatric patients, and ICU patients?..
  13. ncbi request reprint Care of the chronic tracheostomy
    Rajiv Dhand
    Division of Pulmonary, Critical Care, and Environmental Medicine, Department of Internal Medicine, University of Missouri Columbia, Columbia, MO 65212, USA
    Respir Care 51:984-1001; discussion 1002-4. 2006
    ..Appropriate and skilled care could significantly improve the longevity and quality of life of those patients with neuromuscular disease who have a tracheostomy for long-term ventilation...
  14. ncbi request reprint Basic techniques for aerosol delivery during mechanical ventilation
    Rajiv Dhand
    Division of Pulmonary, Critical Care, and Environmental Medicine, MA 421 Health Sciences Center DC043 00, 1 Hospital Drive, University of Missouri Columbia, Columbia, MO 65212, USA
    Respir Care 49:611-22. 2004
    ..The ability to efficiently deliver aerosols should lead to wider clinical application of inhaled therapies in patients receiving mechanical ventilation...
  15. ncbi request reprint New frontiers in aerosol delivery during mechanical ventilation
    Rajiv Dhand
    Department of Internal Medicine, MA 421 Health Sciences Center, DC043 00, 1 Hospital Drive, University of Missouri Columbia, Columbia, MO 65212, USA
    Respir Care 49:666-77. 2004
    ..Research is unraveling the causes of some disorders that have been poorly understood, and our improved understanding of the causal mechanisms of various respiratory disorders will provide new applications for inhaled therapies...
  16. ncbi request reprint Ventilator graphics and respiratory mechanics in the patient with obstructive lung disease
    Rajiv Dhand
    Division of Pulmonary, Critical Care, and Environmental Medicine, Department of Internal Medicine, University of Missouri Columbia, Columbia, MO 65212, USA
    Respir Care 50:246-61; discussion 259-61. 2005
    ..Thus, ventilator waveforms play an important role in management of mechanically-ventilated patients with obstructive lung disease...
  17. ncbi request reprint Inhalation therapy with metered-dose inhalers and dry powder inhalers in mechanically ventilated patients
    Rajiv Dhand
    Division of Pulmonary, Critical Care, and Environmental Medicine, Department of Internal Medicine, University of Missouri Columbia, 65212, USA
    Respir Care 50:1331-4; discussion 1344-5. 2005
    ..In mechanically ventilated patients, pMDIs are a cost-effective, convenient, and safe method for delivering bronchodilator aerosols...
  18. doi request reprint Targeted combined aerosol chemotherapy in dogs and radiologic toxicity grading
    Kim Selting
    Department of Veterinary Medicine and Surgery, University of Missouri, 900 E Campus Drive, Columbia, MO 65211, USA
    J Aerosol Med Pulm Drug Deliv 24:43-8. 2011
    ..We investigated whether combination chemotherapy, targeted with the AeroProbeĀ® Intracorporeal Nebulizing Catheter (INC), could be safely administered, and developed a radiologic grading scheme to monitor subclinical effects on the lungs...
  19. ncbi request reprint Aerosol delivery of recombinant human DNase I: in vitro comparison of a vibrating-mesh nebulizer with a jet nebulizer
    Jeremy C Johnson
    Division of Pulmonary, Critical Care, and Environmental Medicine, University of Missouri Columbia, Columbia, MO 65212, USA
    Respir Care 53:1703-8. 2008
    ..Because of their portability, newer-generation vibrating-mesh nebulizers offer greater convenience for the patient, but their efficiency in delivering rhDNase has not been determined...
  20. doi request reprint Feasibility and safety of targeted cisplatin delivery to a select lung lobe in dogs via the AeroProbe intracorporeal nebulization catheter
    Kim Selting
    Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, Missouri 65211, USA
    J Aerosol Med Pulm Drug Deliv 21:255-68. 2008
    ..Targeted inhaled chemotherapy could be a promising method of treatment for primary and secondary lung tumors...
  21. ncbi request reprint Increasing p53 protein sensitizes non-small cell lung cancer to paclitaxel and cisplatin in vitro
    Vamsi P Guntur
    Division of Pulmonary, Critical Care, and Environmental Medicine, School of Medicine, University of Missouri, Five Hospital Drive, Columbia, MO 65212, USA
    Anticancer Res 30:3557-64. 2010
    ..To determine whether increasing p53 protein levels confers enhanced chemosensitivity in non-small cell lung cancer (NSCLC)...
  22. ncbi request reprint Perioperative treatment of patients with obstructive sleep apnea
    Sanjay S Jain
    Division of Pulmonary, Critical Care and Environmental Medicine, University of Missouri Columbia and Harry S Truman VA Hospital, Columbia, Missouri 65212, USA
    Curr Opin Pulm Med 10:482-8. 2004
    ..The aim of this article is to emphasize the importance of recognizing and appropriately treating surgical patients with obstructive sleep apnea...
  23. ncbi request reprint Sleep disorders in pregnancy
    Pradeep K Sahota
    Department of Neurology and University of Missouri Sleep Disorders Center, University of Missouri Health Care, Columbia, Missouri 65212, USA
    Curr Opin Pulm Med 9:477-83. 2003
    ..Given that limitation, we are presenting an up-to-date review of the current understanding of the relation between sleep and pregnancy...
  24. ncbi request reprint Sleep disorders in neuromuscular diseases
    Upinder K Dhand
    Department of Neurology, Division of Pulmonary, Critical Care and Environmental Medicine, University of Missouri, Columbia, Missouri 65212, USA
    Curr Opin Pulm Med 12:402-8. 2006
    ..This paper reviews the mechanisms, diagnostic evaluation, and management of sleep disorders in various neuromuscular diseases...
  25. doi request reprint Inhaled antibiotic therapy for ventilator-associated tracheobronchitis and ventilator-associated pneumonia: an update
    Tareq Abu-Salah
    Division of Pulmonary, Critical Care, and Environmental Medicine, Department of Internal Medicine, University of Missouri, Columbia, MO 65212, USA
    Adv Ther 28:728-47. 2011
    ..In contrast to VAP, VAT could be effectively treated with inhaled antibiotic therapy alone or in combination with systemic antimicrobials...
  26. ncbi request reprint Inhaled insulin: extending the horizons of inhalation therapy
    Vamsi P Guntur
    Division of Pulmonary, Critical Care, and Environmental Medicine, MA 421 Health Sciences Center, DC043 00, 1 Hospital Drive, University of Missouri Columbia, Columbia MO 65212, USA
    Respir Care 52:911-22. 2007
    ..5-7.0%) in poorly controlled diabetic patients outweigh its disadvantages...
  27. doi request reprint Enantiomer-specific effects of albuterol on airway inflammation in healthy and asthmatic cats
    Carol R Reinero
    Department of Veterinary Medicine and Surgery, School of Veterinary Medicine, University of Missouri, 900 East Campus Drive, Columbia, MO 65211, USA
    Int Arch Allergy Immunol 150:43-50. 2009
    ..We hypothesized that regular administration of R,S-albuterol or S-albuterol, but not R-albuterol, would induce airway inflammation in healthy and asthmatic cats...
  28. ncbi request reprint Aerosol plumes: slow and steady wins the race
    Rajiv Dhand
    J Aerosol Med 18:261-3. 2005
  29. ncbi request reprint Device selection and outcomes of aerosol therapy: Evidence-based guidelines: American College of Chest Physicians/American College of Asthma, Allergy, and Immunology
    Myrna B Dolovich
    Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada
    Chest 127:335-71. 2005
    ..There are advantages and disadvantages associated with each device category. Evidence-based guidelines for the selection of the appropriate aerosol delivery device in specific clinical settings are needed...
  30. ncbi request reprint Bronchodilator therapy in mechanically ventilated patients: patient selection and clinical outcomes
    Rajiv Dhand
    Respir Care 52:152-3. 2007
  31. ncbi request reprint Aerosol bronchodilator therapy during noninvasive positive-pressure ventilation: a peek through the looking glass
    Rajiv Dhand
    Respir Care 50:1621-2. 2005
  32. ncbi request reprint Aerosol therapy during mechanical ventilation: getting ready for prime time
    Rajiv Dhand
    Am J Respir Crit Care Med 168:1148-9. 2003
  33. ncbi request reprint Maximizing aerosol delivery during mechanical ventilation: go with the flow and go slow
    Rajiv Dhand
    Intensive Care Med 29:1041-2. 2003