Research Topics
Species | Girish DhallSummaryAffiliation: University of Southern California Country: USA Publications
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Publications
Pineal region tumors in childrenGirish Dhall
Division of Pediatric Hematology Oncology at Children s Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California 90027, USA
Curr Opin Neurol 23:576-82. 2010..Pineal tumors are rare in children, with pineoblastoma and germ cell tumors (GCTs) being the most common. Here we discuss recent advances in treatment and controversies in the management of these tumors...
Analysis of outcome for patients with mass lesions of the central nervous system due to Langerhans cell histiocytosis treated with 2-chlorodeoxyadenosineGirish Dhall
Children s Hospital Los Angeles, Los Angeles, California, USA
Pediatr Blood Cancer 50:72-9. 2008..To assess the activity and tolerability of 2-chlorodeoxyadenosine (2-CDA) in treating mass lesions of the central nervous system (CNS) due to Langerhans cell histiocytosis (LCH)...
Outcome of children less than three years old at diagnosis with non-metastatic medulloblastoma treated with chemotherapy on the "Head Start" I and II protocolsGirish Dhall
Childrens Hospital Los Angeles, Los Angeles, California, USA
Pediatr Blood Cancer 50:1169-75. 2008..To determine the survival of infants and young children with non-metastatic medulloblastoma using intensive myeloablative chemotherapy and autologous hematopoietic progenitor cell rescue (AuHCR)...
The role of chemotherapy in pediatric clival chordomasGirish Dhall
Neural Tumors Program, The Division of Pediatric Hematology Oncology and Department of Pathology at Childrens Hospital Los Angeles, Los Angeles, CA, USA
J Neurooncol 103:657-62. 2011..Chemotherapy with ifosfamide and etoposide may have a role in the treatment of pediatric clival chordomas when used alone or in combination with irradiation...
MedulloblastomaGirish Dhall
Children s Center for Cancer and Blood Diseases, Division of Pediatric Hematology Oncology, Childrens Hospital Los Angeles, Los Angeles, CA 90027, USA
J Child Neurol 24:1418-30. 2009....
Neurocognitive outcomes in pediatric and adolescent patients with central nervous system germinoma treated with a strategy of chemotherapy followed by reduced-dose and volume irradiationSharon O'Neil
Neural Tumors Program, Center for Cancer and Blood Diseases, Children s Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Pediatr Blood Cancer 57:669-73. 2011..Evaluation of neurocognitive outcomes after a treatment strategy of chemotherapy followed by reduced-dose and volume irradiation for primary central nervous system (CNS) germinoma...
Elevated citrate in pediatric astrocytomas with malignant progressionStefan Bluml
Department of Radiology, Children s Hospital Los Angeles, MS 81, 4650 Sunset Boulevard, Los Angeles, CA 90027, USA
Neuro Oncol 13:1107-17. 2011..Citrate was not specific for poor outcome because it was not detectable in all high-grade astrocytomas. In high-grade astrocytoma, tumors with prominent citrate may constitute a metabolic subclass...
Myeloablative chemotherapy with autologous bone marrow rescue in children and adolescents with recurrent malignant astrocytoma: outcome compared with conventional chemotherapy: a report from the Children's Oncology GroupJonathan L Finlay
The Children s Center for Cancer and Blood Diseases, Department of Pediatrics, Children s Hospital, Los Angeles, California 90027, USA
Pediatr Blood Cancer 51:806-11. 2008..Children and adolescents with malignant astrocytomas recurring after initial treatment have a dismal prognosis, with only rare patients surviving 1-year beyond recurrence. The purpose of this study was to attempt to improve their survival...
Treatment of primary CNS germinomatous germ cell tumors with chemotherapy prior to reduced dose whole ventricular and local boost irradiationSoumen Khatua
Neural Tumors Program, Center for Cancer and Blood Diseases, Childrens Hospital Los Angeles, Los Angeles, California, USA
Pediatr Blood Cancer 55:42-6. 2010..The purpose of this study was to evaluate a reduced irradiation dose strategy for newly diagnosed primary central nervous system (CNS) germinomas...
Treatment of children with recurrent high grade gliomas with a bevacizumab containing regimenChintan Parekh
Division of Pediatric Hematology Oncology, Childrens Hospital Los Angeles, 4650 Sunset Boulevard, MS 54, Los Angeles, CA 90027, USA
J Neurooncol 103:673-80. 2011..However, bevacizumab containing regimens might be effective in a subset of pediatric patients, especially those with predominantly contrast-enhancing disease...
High-dose chemotherapy and autologous hematopoietic progenitor cell rescue in children with recurrent medulloblastoma and supratentorial primitive neuroectodermal tumors: the impact of prior radiotherapy on outcomeAnna M Butturini
Division of Hematology Oncology, Childrens Hospital Los Angeles and Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Cancer 115:2956-63. 2009....
Regression of primary central nervous system germinoma after dexamethasone administration: a case reportStephanie J Si
Neural Tumors Program, Children s Center for Cancer and Blood Diseases, Childrens Hospital Los Angeles, Los Angeles, California, USA
Pediatr Hematol Oncol 27:237-43. 2010..Perioperative corticosteroid administration in patients with CNS germinoma may obfuscate the increase in response demonstrated with various chemotherapy regimens or with irradiation in CNS germinomas...
Choroid plexus tumors; management, outcome, and association with the Li-Fraumeni syndrome: the Children's Hospital Los Angeles (CHLA) experience, 1991-2010Alexa E Gozali
Children s Center for Cancer and Blood Diseases, Children s Hospital, Los Angeles, CA, USA
Pediatr Blood Cancer 58:905-9. 2012..We have investigated the clinical features and overall survival of all CPT patients treated at Children's Hospital Los Angeles (CHLA) over a 20-year period, with particular attention to the association of CPT with LFS...
Recurrent pure CNS germinoma with markedly elevated serum and cerebrospinal fluid human chorionic gonadotropin-beta (HCGβ)Soumen Khatua
Neural Tumors Program, Center for Cancer and Blood Diseases, Childrens Hospital Los Angeles, Los Angeles, CA, USA
Pediatr Blood Cancer 56:863-4. 2011..This case illustrates the need to re-evaluate the assumption that pathologically pure germinomas may be associated with high levels of HCGβ which are unrelated to nongerminomatous germ cell tumor (NGGCT)/choriocarcinomatous elements...
Subacute methotrexate neurotoxicity and cerebral venous sinus thrombosis in a 12-year-old with acute lymphoblastic leukemia and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism: homocysteine-mediated methotrexate neurotoxicity via direct endKris M Mahadeo
Division of Pediatric Hematology Oncology, Children s Hospital at Montefiore, Bronx, New York 10467, USA
Pediatr Hematol Oncol 27:46-52. 2010..The role of homocysteine as a possible mediator in methotrexate-induced neurotoxicity via direct endothelial injury is discussed...
Cerebral sinus thrombosis in a child with active ulcerative colitis and factor V LeidenNathan J Robison
Division of Pediatric Hematology Oncology, Department of Pediatrics, Childrens Hospital Los Angeles, Los Angeles, California 90027, USA
Pediatr Blood Cancer 52:867-9. 2009..Enoxaparin was then used for prophylaxis during acute exacerbations of his UC without any recurrence/progression of cerebral venous thrombosis. This report describes a cerebral thrombotic event in a child with UC and factor V Leiden...
Supratentorial ependymoma in children: to observe or to treat following gross total resection?Rajkumar Venkatramani
Division of Hematology Oncology, Children s Hospital Los Angeles, 4650 Sunset Boulevard, Los Angeles, CA 90027, USA
Pediatr Blood Cancer 58:380-3. 2012..The role of radiation therapy in completely resected supratentorial ependymoma has been questioned over the past two decades...
Primary mixed glioneuronal tumor of the central nervous system in a patient with noonan syndrome: a case report and review of the literatureCourtney B Sherman
Children s Center for Cancer and Blood Diseases, Los Angeles, CA, USA
J Pediatr Hematol Oncol 31:61-4. 2009....
Ki-67 proliferative index predicts progression-free survival of patients with well-differentiated ileal neuroendocrine tumorsDeepti Dhall
Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Hum Pathol 43:489-95. 2012..In conclusion, the Ki-67 index predicts PFS of patients with ileal wNETs...
Exacerbation of anthracycline-induced early chronic cardiomyopathy with ATRA: role of B-type natriuretic peptide as an indicator of cardiac dysfunctionKris Michael Mahadeo
Division of Pediatric Hematology Oncology, Children s Hospital at Montefiore, Bronx, NY, USA
J Pediatr Hematol Oncol 32:134-6. 2010..Improvement and deterioration in systolic function on echocardiogram and serum B-natriuretic peptide levels were seen while receiving ATRA 1 week on and 1 week off, respectively, during the maintenance phase of therapy...
Thymoma in children: report of two cases and review of literatureGirish Dhall
Division of Pediatric Hematology Oncology, St Peter s University Hospital, New Brunswick, NJ 08903 0591, USA
J Pediatr Hematol Oncol 26:681-5. 2004..Both patients remain free of disease 3 years after surgery. One of the patients also has nevus sebaceous. The authors also discuss the possible association between the two disease entities...
