Jason J DeVoss

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Lessons on immune tolerance from the monogenic disease APS1
    Jason J DeVoss
    University of California San Francisco Diabetes Center, HSW1102, San Francisco, CA 94143 0540, USA
    Curr Opin Genet Dev 17:193-200. 2007
  2. ncbi An autoimmune response to odorant binding protein 1a is associated with dry eye in the Aire-deficient mouse
    Jason J DeVoss
    Diabetes Center, University of California San Francisco, San Francisco, CA 94143, USA
    J Immunol 184:4236-46. 2010
  3. ncbi Effector mechanisms of the autoimmune syndrome in the murine model of autoimmune polyglandular syndrome type 1
    Jason J DeVoss
    Diabetes Center, University of California, San Francisco, CA 94143, USA
    J Immunol 181:4072-9. 2008
  4. ncbi Deletional tolerance mediated by extrathymic Aire-expressing cells
    James M Gardner
    Diabetes Center, University of California San Francisco UCSF, San Francisco, CA 94122, USA
    Science 321:843-7. 2008
  5. ncbi A novel myelin P0-specific T cell receptor transgenic mouse develops a fulminant autoimmune peripheral neuropathy
    Cedric Louvet
    Diabetes Center and the Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA
    J Exp Med 206:507-14. 2009
  6. ncbi Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection
    Ruth T Taniguchi
    Diabetes Center, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 109:7847-52. 2012
  7. ncbi Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire
    Maureen A Su
    Diabetes Center, Department of Pediatric, UCSF, San Francisco, California 94143, USA
    J Clin Invest 118:1712-26. 2008

Collaborators

Detail Information

Publications7

  1. ncbi Lessons on immune tolerance from the monogenic disease APS1
    Jason J DeVoss
    University of California San Francisco Diabetes Center, HSW1102, San Francisco, CA 94143 0540, USA
    Curr Opin Genet Dev 17:193-200. 2007
    ..Recent work on the monogenic autoimmune disease 'autoimmune polyglandular syndrome type 1' (APS1) and on the causal gene of this disorder--autoimmune regulator (AIRE)--is providing new lessons on how immune tolerance is maintained...
  2. ncbi An autoimmune response to odorant binding protein 1a is associated with dry eye in the Aire-deficient mouse
    Jason J DeVoss
    Diabetes Center, University of California San Francisco, San Francisco, CA 94143, USA
    J Immunol 184:4236-46. 2010
    ....
  3. ncbi Effector mechanisms of the autoimmune syndrome in the murine model of autoimmune polyglandular syndrome type 1
    Jason J DeVoss
    Diabetes Center, University of California, San Francisco, CA 94143, USA
    J Immunol 181:4072-9. 2008
    ..Depletion of CD4(+) T cells using a neutralizing Ab ameliorated the disease process. Thus, therapies targeted specifically at the CD4(+) T cell subset may help control autoimmune disease in patients with APS1...
  4. ncbi Deletional tolerance mediated by extrathymic Aire-expressing cells
    James M Gardner
    Diabetes Center, University of California San Francisco UCSF, San Francisco, CA 94122, USA
    Science 321:843-7. 2008
    ..We propose that such a secondary network of self-antigen-expressing stromal cells may help reinforce immune tolerance by preventing the maturation of autoreactive T cells that escape thymic negative selection...
  5. ncbi A novel myelin P0-specific T cell receptor transgenic mouse develops a fulminant autoimmune peripheral neuropathy
    Cedric Louvet
    Diabetes Center and the Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA
    J Exp Med 206:507-14. 2009
    ..Collectively, our data suggest that myelin P0 is a major autoantigen in autoimmune peripheral neuropathy...
  6. ncbi Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection
    Ruth T Taniguchi
    Diabetes Center, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 109:7847-52. 2012
    ..Furthermore, our data suggest that Aire-mediated deletion relies not only on thymic expression of IRBP, but also on proper antigen processing and presentation of IRBP by thymic antigen-presenting cells...
  7. ncbi Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire
    Maureen A Su
    Diabetes Center, Department of Pediatric, UCSF, San Francisco, California 94143, USA
    J Clin Invest 118:1712-26. 2008
    ..Together, these results may demonstrate a mechanism by which autoimmune predisposition to phenotypes distinct from APS 1 can be mediated in a dominant-negative fashion by Aire...