R Detels

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Tracing sexual contacts of HIV-infected individuals in a rural prefecture, Eastern China
    Haijiang Lin
    Department of Epidemiology, School of Public Health, Fudan University, Shanghai, China
    BMC Public Health 12:533. 2012
  2. pmc The multicenter AIDS Cohort Study, 1983 to …
    R Detels
    School of Public Health, University of California, Los Angeles, United States
    Public Health 126:196-8. 2012
  3. pmc Air pollution and case fatality of SARS in the People's Republic of China: an ecologic study
    Yan Cui
    Department of Epidemiology, School of Public Health, University of California at Los Angeles, CA 90095, USA
    Environ Health 2:15. 2003
  4. pmc HIV transmission potential among local and migrant factory workers in Kolkata, India
    Alok Kumar Deb
    National Institute of Cholera and Enteric Diseases, Kolkata, India
    AIDS Behav 13:928-38. 2009
  5. pmc The search for protection against HIV infection
    Roger Detels
    School of Public Health, Department of Epidemiology, University of California Los Angeles, 650 Charles Young Drive, Los Angeles, CA 90085 1772, USA
    Ann Epidemiol 19:250-2. 2009
  6. ncbi request reprint Effectiveness of potent antiretroviral therapies on the incidence of opportunistic infections before and after AIDS diagnosis
    R Detels
    School of Public Health, University of California, Los Angeles, 90095 1772, USA
    AIDS 15:347-55. 2001
  7. ncbi request reprint HIV/AIDS in Asia: introduction
    Roger Detels
    The Department of Epidemiology, UCLA School of Public Health, Los Angeles, CA 90095 1772, USA
    AIDS Educ Prev 16:1-6. 2004
  8. ncbi request reprint Effectiveness of potent antiretroviral therapy on time to AIDS and death in men with known HIV infection duration. Multicenter AIDS Cohort Study Investigators
    R Detels
    School of Public Health, University of California, Los Angeles 90095 1772, USA
    JAMA 280:1497-503. 1998
  9. pmc The incidence and correlates of symptomatic and asymptomatic Chlamydia trachomatis and Neisseria gonorrhoeae infections in selected populations in five countries
    Roger Detels
    Department of Epidemiology, UCLA School of Public Health, 71 269 CHS, Box 951772, Los Angeles, CA 90095 1772, USA
    Sex Transm Dis 38:503-9. 2011
  10. ncbi request reprint Sexually transmitted disease prevalence and characteristics of market vendors in eastern China
    Roger Detels
    Department of Epidemiology, School of Public Health, University of California, Los Angeles, Los Angeles, California 90095 1772, USA
    Sex Transm Dis 30:803-8. 2003

Research Grants

  1. INTERDISCIPLINARY TRAINING IN HIV/AIDS EPIDEMIOLOGY
    Roger Detels; Fiscal Year: 2005
  2. NATURAL HISTORY OF AIDS IN HOMOSEXUAL MEN
    Roger Detels; Fiscal Year: 2007

Collaborators

Detail Information

Publications115 found, 100 shown here

  1. pmc Tracing sexual contacts of HIV-infected individuals in a rural prefecture, Eastern China
    Haijiang Lin
    Department of Epidemiology, School of Public Health, Fudan University, Shanghai, China
    BMC Public Health 12:533. 2012
    ..Contact tracing is especially useful for identifying an infection with few cases in the population, such as HIV in China. Little such research is available in China...
  2. pmc The multicenter AIDS Cohort Study, 1983 to …
    R Detels
    School of Public Health, University of California, Los Angeles, United States
    Public Health 126:196-8. 2012
    ..Through May 2011, 1,490,995 specimens have been collected, 86,883 person-years of data accrued and 1195 scientific papers published in international journals...
  3. pmc Air pollution and case fatality of SARS in the People's Republic of China: an ecologic study
    Yan Cui
    Department of Epidemiology, School of Public Health, University of California at Los Angeles, CA 90095, USA
    Environ Health 2:15. 2003
    ..SARS case fatality has varied across geographical areas, which might be partially explained by air pollution level...
  4. pmc HIV transmission potential among local and migrant factory workers in Kolkata, India
    Alok Kumar Deb
    National Institute of Cholera and Enteric Diseases, Kolkata, India
    AIDS Behav 13:928-38. 2009
    ..There is great potential for transmission of HIV/sexually transmitted infections by these workers. Carefully designed intervention and education programs in the context of low literacy and cultural norms are urgently needed...
  5. pmc The search for protection against HIV infection
    Roger Detels
    School of Public Health, Department of Epidemiology, University of California Los Angeles, 650 Charles Young Drive, Los Angeles, CA 90085 1772, USA
    Ann Epidemiol 19:250-2. 2009
    ..Subsequent studies have lent support to this hypothesis...
  6. ncbi request reprint Effectiveness of potent antiretroviral therapies on the incidence of opportunistic infections before and after AIDS diagnosis
    R Detels
    School of Public Health, University of California, Los Angeles, 90095 1772, USA
    AIDS 15:347-55. 2001
    ..To determine the effectiveness of potent antiretroviral therapy in reducing opportunistic infections (OI) as both a presenting event and subsequent to an AIDS-defining event...
  7. ncbi request reprint HIV/AIDS in Asia: introduction
    Roger Detels
    The Department of Epidemiology, UCLA School of Public Health, Los Angeles, CA 90095 1772, USA
    AIDS Educ Prev 16:1-6. 2004
  8. ncbi request reprint Effectiveness of potent antiretroviral therapy on time to AIDS and death in men with known HIV infection duration. Multicenter AIDS Cohort Study Investigators
    R Detels
    School of Public Health, University of California, Los Angeles 90095 1772, USA
    JAMA 280:1497-503. 1998
    ..Cohort studies following up persons with human immunodeficiency virus (HIV) infection in periods characterized by different therapies offer the opportunity to estimate therapy effectiveness at the population level...
  9. pmc The incidence and correlates of symptomatic and asymptomatic Chlamydia trachomatis and Neisseria gonorrhoeae infections in selected populations in five countries
    Roger Detels
    Department of Epidemiology, UCLA School of Public Health, 71 269 CHS, Box 951772, Los Angeles, CA 90095 1772, USA
    Sex Transm Dis 38:503-9. 2011
    ..Asymptomatic Chlamydia trachomatis (chlamydia) and Neisseria gonorrhoeae (gonorrhea) infections pose diagnostic and control problems in developing countries...
  10. ncbi request reprint Sexually transmitted disease prevalence and characteristics of market vendors in eastern China
    Roger Detels
    Department of Epidemiology, School of Public Health, University of California, Los Angeles, Los Angeles, California 90095 1772, USA
    Sex Transm Dis 30:803-8. 2003
    ..Sexually transmitted diseases (STDs) have soared in China. To address the impact, we studied market stall vendors in eastern China...
  11. ncbi request reprint Increase and plateau of CD4 T-cell counts in the 3(1/2) years after initiation of potent antiretroviral therapy
    P M Tarwater
    Department of Epidemiology, Johns Hopkins School of Hygiene and Public Health, 615 N Wolfe St, Baltimore, MD 21205, USA
    J Acquir Immune Defic Syndr 27:168-75. 2001
    ..The single most important predictor of the steady state CD4 cell count that was maintained between 2 and 3(1/2) years after initiation was the change in plasma HIV-RNA in the first year after initiation of potent ART...
  12. ncbi request reprint Methods to assess population effectiveness of therapies in human immunodeficiency virus incident and prevalent cohorts
    P M Tarwater
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Am J Epidemiol 154:675-81. 2001
    ..38), and 0.31 (95% CI: 0.21, 0.45). These results extend the measurement of population effectiveness from incident to prevalent cohorts and demonstrate the ability of cohort studies to complement information provided by clinical trials...
  13. ncbi request reprint Therapy naivete in the era of potent antiretroviral therapy
    L P Jacobson
    Department of Epidemiology, The Johns Hopkins School of Hygiene and Public Health, Baltimore, MD 21205, USA
    J Clin Epidemiol 54:149-56. 2001
    ..In this era of effective ART, use was not universal. Besides disease markers, these nonclinical determinants need to be considered for promoting population therapy effectiveness...
  14. ncbi request reprint Thrush and fever as markers of immune competence in the era of highly active antiretroviral therapy
    R L Skolasky
    Department of Epidemiology, Johns Hopkins University School of Public Health, 615 N. Wolfe Street, Baltimore, MD 21205, USA
    AIDS Res Hum Retroviruses 17:1311-6. 2001
    ..These results provide evidence that increases in CD4+ T cell count due to HAART represent a reconstitution of immune function...
  15. ncbi request reprint Longitudinal patterns of HIV type 1 RNA among individuals with late disease progression
    S J Gange
    Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    AIDS Res Hum Retroviruses 17:1223-9. 2001
    ..8 years prior to the onset of AIDS. These results provide evidence that an increase in the slope of plasma levels of HIV RNA is a sign of incipient progression of HIV disease...
  16. ncbi request reprint Evaluation of the effectiveness of highly active antiretroviral therapy in persons with human immunodeficiency virus using biomarker-based equivalence of disease progression
    L P Jacobson
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Am J Epidemiol 155:760-70. 2002
    ....
  17. ncbi request reprint Determinants of heterogeneous adherence to HIV-antiretroviral therapies in the Multicenter AIDS Cohort Study
    C A Kleeberger
    Department of Epidemiology, The Johns Hopkins School of Hygiene and Public Health, Baltimore, Maryland 21205, USA
    J Acquir Immune Defic Syndr 26:82-92. 2001
    ..Identification of individuals with characteristics associated with lower adherence provides the basis for interventions to enhance adherence and optimize effective therapies...
  18. pmc Identification of inflections in T-cell counts among HIV-1-infected individuals and relationship with progression to clinical AIDS
    S J Gange
    Department of Epidemiology, Johns Hopkins School of Hygiene and Public Health, Baltimore, MD 21205, USA
    Proc Natl Acad Sci U S A 95:10848-53. 1998
    ....
  19. ncbi request reprint Predictive value of immunologic and virologic markers after long or short duration of HIV-1 infection
    Janis V Giorgi
    UCLA School of Medicine and Center for AIDS Research, Los Angeles, California 90095 1475, USA
    J Acquir Immune Defic Syndr 29:346-55. 2002
    ....
  20. ncbi request reprint The effects of establishment practices, knowledge and attitudes on condom use among Filipina sex workers
    D E Morisky
    University of California, Los Angeles, USA, School of Public Health, Center for Health Sciences 90095 1772, USA
    AIDS Care 10:213-20. 1998
    ..The preliminary findings point to the importance of an intervention that stresses changes in establishment policies and expectations as a means of reducing risk behaviours associated with HIV/STD transmission...
  21. ncbi request reprint Fraction of cases of acquired immunodeficiency syndrome prevented by the interactions of identified restriction gene variants
    M J Silverberg
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Am J Epidemiol 159:232-41. 2004
    ..Additional research is needed to identify AIDS restriction genes with stronger and long-lasting protection to better characterize the genetic epidemiology of HIV-1...
  22. ncbi request reprint Patterns of the hazard of death after AIDS through the evolution of antiretroviral therapy: 1984-2004
    Michael F Schneider
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, MD 21205, USA
    AIDS 19:2009-18. 2005
    ..To characterize changing survival patterns after development of clinical AIDS from 1984 to 2004, when different antiretroviral therapies were being introduced...
  23. ncbi request reprint Stigma, delayed treatment, and spousal notification among male patients with sexually transmitted disease in China
    Hongjie Liu
    School of Public Health, University of California, Los Angeles, Los Angeles, California 90095 1772, USA
    Sex Transm Dis 29:335-43. 2002
    ..Stigmatization may prevent effective control of sexually transmitted diseases (STDs) in China. Thus, its impact needs to be studied...
  24. ncbi request reprint Rapid declines in total lymphocyte counts and hemoglobin concentration prior to AIDS among HIV-1-infected men
    Bryan Lau
    Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    AIDS 17:2035-44. 2003
    ..To describe temporal patterns in total lymphocyte count (TLC) and hemoglobin (Hgb) concentration during HIV infection and relate these patterns to changes in other markers and to clinical disease...
  25. ncbi request reprint The role of epidemiology in challenging the HIV/AIDS pandemic
    R Detels
    University of California, Los Angeles School of Public Health, USA
    J Epidemiol 11:95-102. 2001
    ..Examples of the application of these epidemiologic strategies are presented...
  26. ncbi request reprint Protease inhibitors and cardiovascular disease: analysis of the Los Angeles County adult spectrum of disease cohort
    G Vaughn
    UCLA School of Public Health, Epidemiology, Los Angeles, USA
    AIDS Care 19:492-9. 2007
    ..Clinicians should monitor treatment of HIV-infected patients for adverse CVD events, and consider alternate forms of drug therapy and CVD-preventing drugs, particularly for those with a personal or family history of CVD...
  27. ncbi request reprint Early versus deferred zidovudine monotherapy: impact on AIDS-free time and survival in the multicenter AIDS cohort study
    R Detels
    Department of Epidemiology, UCLA School of Public Health, Los Angeles, CA 90095 1772, USA
    Antivir Ther 2:21-9. 1997
    ..The analytical technique used is applicable to other observational studies of treatment...
  28. ncbi request reprint Persistent alterations in the T-cell repertoires of HIV-1-infected and at-risk uninfected men
    M Scott Killian
    Division of Hematology Oncology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
    AIDS 18:161-70. 2004
    ..We examined the association between immunogenic exposure and T-cell receptor (TCR) diversity to more clearly assess the impact of HIV-1 infection on the T-cell repertoire...
  29. ncbi request reprint Effect of highly active antiretroviral therapy on survival among HIV-infected men with Kaposi sarcoma or non-Hodgkin lymphoma
    Henry K Tam
    School of Public Health, University of California, Los Angeles, CA 90095 1772, USA
    Int J Cancer 98:916-22. 2002
    ..The use of HAART prolongs overall survival among HIV-positive men diagnosed with KS and NHL. HAART appears to be effective in improving survival even when initiated after the diagnosis of NHL and KS...
  30. ncbi request reprint Sexual behavior among employed male rural migrants in Shanghai, China
    Na He
    Department of Epidemiology, School of Public Health, University of California, Los Angeles, 90095, USA
    AIDS Educ Prev 18:176-86. 2006
    ..Sexually transmitted diseases and HIV are likely to increase among migrants, particularly those who are young. Intervention strategies should target younger migrants, and must accommodate a low literacy level...
  31. ncbi request reprint When to initiate highly active antiretroviral therapy: a cohort approach
    Linda Ahdieh-Grant
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Am J Epidemiol 157:738-46. 2003
    ..Furthermore, results suggest a potential threshold for HAART initiation in the neighborhood of 275 cells/microl...
  32. ncbi request reprint Multiple viral coinfections among HIV/AIDS patients in China
    N He
    Department of Epidemiology, School of Public Health, Fudan University, Shanghai, China
    Biosci Trends 5:1-9. 2011
    ....
  33. ncbi request reprint AIDS diagnosis and depression in the Multicenter AIDS Cohort Study: the ameliorating impact of pet ownership
    J M Siegel
    University of California, Los Angeles, USA
    AIDS Care 11:157-70. 1999
    ..This beneficial effect of pet ownership occurred principally among persons who reported fewer confidants. These results suggest that by enhancing companionship for some HIV-infected persons, pets may buffer the stressful impact of AIDS...
  34. pmc Oral fluids as an alternative to serum for measurement of markers of immune activation
    P Nishanian
    Center for Interdisciplinary Research in Immunology and Disease, Jonsson Comprehensive Cancer Center, School of Medicine, University of California at Los Angeles, 90095 1747, USA
    Clin Diagn Lab Immunol 5:507-12. 1998
    ....
  35. ncbi request reprint Characteristics and sexually transmitted diseases of male rural migrants in a metropolitan area of Eastern China
    Na He
    Department of Epidemiology, School of Public Health, University of California, Los Angeles, Los Angeles, California 90095 1771, USA
    Sex Transm Dis 32:286-92. 2005
    ..The goal of this study was to identify the correlates and determine the prevalence of sexually transmitted diseases (STDs) among male rural migrants in Shanghai, China...
  36. ncbi request reprint Effects of HIV-1 infection on lymphocyte phenotypes in blood versus lymph nodes
    Otto O Yang
    Department of Medicine, Geffen School of Medicine, UCLA Medical Center, University of California, Los Angeles, CA 90095, USA
    J Acquir Immune Defic Syndr 39:507-18. 2005
    ..Thus, blood indirectly reflects processes in lymphoid tissues, and caution should be applied when interpreting immunopathogenesis studies of blood...
  37. pmc HIV infection and risk characteristics among female sex workers in Hanoi, Vietnam
    Trung Nam Tran
    Department of Epidemiology, University of California, Los Angeles, School of Public Health, Los Angeles, CA 90095 1772, USA
    J Acquir Immune Defic Syndr 39:581-6. 2005
    ..Intervention strategies should include reduction of both stigmatization and sharing of drug paraphernalia, promotion of nonstigmatizing voluntary testing and counseling, and aggressive marketing and promotion of condoms...
  38. pmc Visiting entertainment venues and sexual health in China
    Li Li
    Semel Institute for Neuroscience and Human Behavior, Center for Community Health, University of California at Los Angeles, Los Angeles, CA, USA
    Arch Sex Behav 38:814-20. 2009
    ..Gender differences were observed in predicting unprotected sex and STD infections. Entertainment venues could be potential sites for place-based intervention programs and outreach for the general population...
  39. pmc Depression and social support among HIV-affected adolescents
    Sung Jae Lee
    Department of Epidemiology, University of California, Los Angeles, California 90024, USA
    AIDS Patient Care STDS 21:409-17. 2007
    ....
  40. pmc Regulatory T cell expansion and immune activation during untreated HIV type 1 infection are associated with disease progression
    Weiwei Cao
    Department of Epidemiology, School of Public Health, University of California Los Angeles, CA 90095, USA
    AIDS Res Hum Retroviruses 25:183-91. 2009
    ..The high level of Tregs associated with rapid HIV progression may suggest a detrimental role of these cells in the immune control of HIV-1 infection...
  41. ncbi request reprint Serum levels of the homeostatic B cell chemokine, CXCL13, are elevated during HIV infection
    Daniel P Widney
    Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California, 27 139 Center for Health Sciences, 10833 Le Conte Avenue, Los Angeles, CA 90095 1740, USA
    J Interferon Cytokine Res 25:702-6. 2005
    ....
  42. ncbi request reprint Elevated serum soluble CD30 precedes the development of AIDS-associated non-Hodgkin's B cell lymphoma
    Elizabeth Crabb Breen
    Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095 1740, USA
    Tumour Biol 27:187-94. 2006
    ....
  43. doi request reprint Improving reproductive health knowledge in rural China--a web-based strategy
    Songyuan Tang
    Institute for Health Studies, Kunming Medical College, Yunnan, China
    J Health Commun 14:690-714. 2009
    ..Moreover, the knowledge was diffused from the primary population of village doctors, family planning workers, women's cadres, and teachers to the secondary population of villagers and students...
  44. ncbi request reprint Delayed reconstitution of CD4+ iNKT cells after effective HIV type 1 therapy
    Otto O Yang
    Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California 90095, USA
    AIDS Res Hum Retroviruses 23:913-22. 2007
    ....
  45. pmc Mandatory HIV testing in China: the perception of health-care providers
    Li Li
    Center for Community Health, Department of Psychiatry, Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, Los Angeles, CA 90024, USA
    Int J STD AIDS 18:476-81. 2007
    ..Results underscore the importance of implementing universal precautions in health-care settings and call attention to social and ethical issues associated with HIV/AIDS control and treatment in China...
  46. pmc The effect of social support on mental and behavioral outcomes among adolescents with parents with HIV/AIDS
    Sung Jae Lee
    Center for Community Health, University of California, Los Angeles, CA 90024, USA
    Am J Public Health 97:1820-6. 2007
    ..We examined the associations between social support and mental and behavioral outcomes among adolescents whose parents were infected with or died of HIV/AIDS...
  47. pmc Sociocultural contexts and communication about sex in China: informing HIV/STD prevention programs
    Eli Lieber
    Center for Culture and Health, Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA 90024 1759, USA
    AIDS Educ Prev 21:415-29. 2009
    ..Findings illustrate the nature of how sexual communication schemata in Chinese contexts impact the effectiveness of sexual health message communication...
  48. ncbi request reprint Prognostic value of plasma HIV RNA among highly active antiretroviral therapy users
    Patrick M Tarwater
    School of Public Health, University of Texas Health Science Center, 1100 N Stanton, Suite 110, El Paso, TX 79902, USA
    AIDS 18:2419-23. 2004
    ....
  49. ncbi request reprint The impact of social, economic and political forces on emerging HIV epidemics
    Pamina M Gorbach
    Department of Epidemiology, School of Public Health, University of California, Los Angeles, CA 90095 1772, USA
    AIDS 16:S35-43. 2002
  50. pmc Using case vignettes to measure HIV-related stigma among health professionals in China
    Li Li
    UCLA NPI Center for Community Health, University of California Los Angeles, 10920 Wilshire Boulevard, Los Angeles, CA 90024, USA
    Int J Epidemiol 36:178-84. 2007
    ..We examined Chinese health professionals' attitudes towards patients with AIDS vs patients with hepatitis B...
  51. pmc MaGiK method of T-Cell receptor repertoire analysis
    M Scott Killian
    Department of Epidemiology, University of California, Los Angeles, California 90095, USA
    Clin Diagn Lab Immunol 9:858-63. 2002
    ..Here, we describe a novel analysis method, termed the MaGiK method, for systematically identifying and enumerating clonal T-cell expansions and for applying the results to investigations of the T-cell receptor repertoire...
  52. ncbi request reprint Non-Hodgkin's B cell lymphoma in persons with acquired immunodeficiency syndrome is associated with increased serum levels of IL10, or the IL10 promoter -592 C/C genotype
    Elizabeth Crabb Breen
    Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    Clin Immunol 109:119-29. 2003
    ..009), even when controlling for race (P = 0.006). These results suggest that elevated serum IL10 or the IL10 promoter -592 C/C genotype are associated with development of AIDS lymphoma...
  53. ncbi request reprint Validity of self-reporting of episodes of external genital warts
    D J Wiley
    Division of Primary Care, School of Nursing, University of California at Los Angeles, Los Angeles, CA, 90095, USA
    Clin Infect Dis 35:39-45. 2002
    ..06-0.09). Self-diagnosis and self-assessment may not accurately reflect the presence of EGWs, and self-diagnosis should not be used in place of an examiner's findings for epidemiologic studies that seek to determine the cause of disease...
  54. pmc Impact of paediatric human immunodeficiency virus infection on children's and caregivers' daily functioning and well-being: a qualitative study
    W Punpanich
    Department of Epidemiology, UCLA School of Public Health, Los Angeles, CA, USA
    Child Care Health Dev 38:714-22. 2012
    ..The purpose of this study was to enhance our understanding of the impact of HIV disease on both children's and caregivers' well-being, using a qualitative inquiry approach...
  55. ncbi request reprint Association of polymorphisms in human leukocyte antigen class I and transporter associated with antigen processing genes with resistance to human immunodeficiency virus type 1 infection
    Chenglong Liu
    School of Public Health, University of California, Los Angeles, CA 90095, USA
    J Infect Dis 187:1404-10. 2003
    ..In multivariate logistic analysis, only the A*0205 subgroup (OR, 5.56; 95% CI, 1.34-23.10; P=.018) and the TAP2 Ala665 (OR, 2.22; 95% CI, 1.28-3.84; P=.005) were associated with resistance...
  56. ncbi request reprint Factors affecting hepatitis vaccination refusal at a sexually transmitted disease clinic among men who have sex with men
    Ellen T Rudy
    Departments of Health Services and Epidemiology, UCLA, School of Public Health, 650 Charles E Young Drive South, Box 951772, Los Angeles, CA 90095 1772, USA
    Sex Transm Dis 30:411-8. 2003
    ..However, vaccination rates in STD clinics remain less than optimal...
  57. ncbi request reprint Application of case-crossover and case-time-control study designs in analyses of time-varying predictors of T-cell homeostasis failure
    Michael F Schneider
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Ann Epidemiol 15:137-44. 2005
    ..75 years prior to an initial diagnosis of acquired immunodeficiency syndrome (AIDS)...
  58. ncbi request reprint Correlates of HIV infection among former blood/plasma donors in rural China
    Guoping Ji
    School of Public Health, University of California, Los Angeles, California 90095 1772, USA
    AIDS 20:585-91. 2006
    ..In 1995, when the first cases of HIV infection were reported among former plasma donors (FPDs), the Chinese government closed all commercial plasma collection stations...
  59. pmc HIV/STD prevalence among men who have sex with men in Chengdu, China and associated risk factors for HIV infection
    Yuji Feng
    Department of Epidemiology, University of California, Los Angeles, 90095 1772, USA
    J Acquir Immune Defic Syndr 53:S74-80. 2010
    ..To assess the prevalence of HIV and selected sexually transmitted diseases (STDs) among men who have sex with men (MSM) in Chengdu, China, and the risk factors associated with HIV infection...
  60. ncbi request reprint Effect of highly active antiretroviral therapy on multiple AIDS-defining illnesses among male HIV seroconverters
    Lauren E Cain
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, 615 North Wolfe Street E7640, Baltimore, MD 21205, USA
    Am J Epidemiol 163:310-5. 2006
    ..34 (95% CI: 0.25, 0.45) relative to the reference calendar period. HAART protects against initial and subsequent AIDS-defining illnesses, whose inclusion in analysis markedly increased the precision of the estimated hazard ratio...
  61. ncbi request reprint Risk of sexual HIV transmission in a rural area of China
    Guoping Ji
    School of Public Health, University of California, Los Angeles, Los Angeles, CA 90095, USA
    Int J STD AIDS 18:380-3. 2007
    ..Promotion of condoms with all partners and limiting sexual partners are urgently needed to reduce the spread of HIV. Intervention programmes should promote HIV/AIDS education, consistent condom use, and voluntary counselling and testing...
  62. ncbi request reprint Elevated expression of activation induced cytidine deaminase in peripheral blood mononuclear cells precedes AIDS-NHL diagnosis
    Marta Epeldegui
    Department of Microbiology, Immunology and Molecular Genetics, UCLA School of Public Health, Los Angeles, California 90095, USA
    AIDS 21:2265-70. 2007
    ..Additionally, AID expression was seen to differ depending on NHL subtype, with the highest levels of expression seen in those who developed Burkitt's lymphoma...
  63. ncbi request reprint Changes in adherence to highly active antiretroviral therapy medications in the Multicenter AIDS Cohort Study
    Cynthia A Kleeberger
    Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
    AIDS 18:683-8. 2004
    ..To characterize the determinants of changes in adherence to antiretroviral therapy and examine whether there are persistent lower adherers...
  64. ncbi request reprint HIV-related stigma among market workers in China
    Martha B Lee
    Department of Psychiatry and Behavioral Sciences, Neuropsychiatric Institute, Center for Community Health, University of California, Los Angeles, Los Angeles, CA 90024, USA
    Health Psychol 24:435-8. 2005
    ..Punishing beliefs toward persons living with HIV were related to being male, older, married, less educated, and unwilling to be tested for HIV...
  65. pmc Evolution of men who have sex with men community and experienced stigma among men who have sex with men in Chengdu, China
    Yuji Feng
    Department of Epidemiology, University of California, Los Angeles, USA
    J Acquir Immune Defic Syndr 53:S98-103. 2010
    ..To understand the stigma and discrimination experienced by men who have sex with men (MSM) in Chengdu, and to evaluate their impact on effective HIV prevention...
  66. ncbi request reprint Effect of highly active antiretroviral therapy on time to acquired immunodeficiency syndrome or death using marginal structural models
    Stephen R Cole
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Am J Epidemiol 158:687-94. 2003
    ..Standard Cox analysis failed to detect a clear net benefit, because it does not appropriately adjust for time-dependent covariates, such as HIV RNA level and CD4 cell count, that are simultaneously confounders and intermediate variables...
  67. ncbi request reprint Accounting for leadtime in cohort studies: evaluating when to initiate HIV therapies
    Stephen R Cole
    Department of Epidemiology, Johns Hopkins University, Baltimore, MD 21205, USA
    Stat Med 23:3351-63. 2004
    ..70; 95 per cent CI 0.35, 1.42). Methods presented here offer an approach to analysing prevalent cohort studies and provide procedures to maximize the usefulness of observational data...
  68. pmc Factors associated with HIV infection among Indian women
    P Ghosh
    Department of Epidemiology, UCLA School of Public Health, Los Angeles, CA, USA
    Int J STD AIDS 22:140-5. 2011
    ..Empowerment of women is fundamental to HIV/AIDS prevention in India...
  69. pmc Stigmatization and shame: consequences of caring for HIV/AIDS patients in China
    L Li
    University of California, Los Angeles, CA 90024, USA
    AIDS Care 19:258-63. 2007
    ....
  70. ncbi request reprint Do STD clinics correctly diagnose STDs? An assessment of STD management in Hefei, China
    H Liu
    School of Public Health, University of California, Los Angeles, CA 90095 1772, USA
    Int J STD AIDS 14:665-71. 2003
    ..Over half of those previously infected had not received education to prevent reinfection. Thus, the quality of clinic laboratory testing was not high and physicians often misdiagnosed STDs...
  71. pmc Pharmacy workers' sexually transmitted diseases/human immunodeficiency virus knowledge in Fuzhou, China: implications for human immunodeficiency virus testing, treatment, and prevention strategies
    Yi Wen
    Semel Institute for Neuroscience and Human Behavior, Center for Community Health, University of California at Los Angeles, Los Angeles, California 90024, USA
    Sex Transm Dis 36:221-6. 2009
    ..There is a need to study the STD/human immunodeficiency virus (HIV) knowledge among pharmacy workers in retail pharmacies...
  72. pmc Recreational drug use and T lymphocyte subpopulations in HIV-uninfected and HIV-infected men
    Chun Chao
    Department of Epidemiology and Jonsson Comprehensive Cancer Center, University of California at Los Angeles, Los Angeles, CA 90095 1772, USA
    Drug Alcohol Depend 94:165-71. 2008
    ..These results indicate that use of these substances does not adversely affect the numbers and percentages of circulating CD4 or CD8 T cells in either HIV-uninfected or -infected MSM...
  73. doi request reprint Incidence and epidemiology of anal cancer in the multicenter AIDS cohort study
    Gypsyamber D'Souza
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Acquir Immune Defic Syndr 48:491-9. 2008
    ..To examine the incidence and risk factors for anal cancer in a multicenter cohort of human immunodeficiency virus (HIV) positive and HIV-negative men who have sex with men followed between 1984 and 2006 (Multicenter AIDS Cohort Study)...
  74. ncbi request reprint Is syndromic management better than the current approach for treatment of STDs in China? Evaluation of the cost-effectiveness of syndromic management for male STD patients
    Hongjie Liu
    School of Public Health, University of California, Los Angeles, 90095 1772, USA
    Sex Transm Dis 30:327-30. 2003
    ..The syndromic treatment approach has not been evaluated in sexually transmitted disease (STD) clinics in China...
  75. ncbi request reprint Influence of human leukocyte antigen-B22 alleles on the course of human immunodeficiency virus type 1 infection in 3 cohorts of white men
    M Tevfik Dorak
    Department of Epidemiology, University of Alabama at Birmingham, Alabama, USA
    J Infect Dis 188:856-63. 2003
    ..This finding may have greater implications for Asians, because the marker frequency for B22 is higher among Asians than among whites (approximately 10% vs. approximately 4%)...
  76. pmc Effect of highly active antiretroviral therapy on incident AIDS using calendar period as an instrumental variable
    Lauren E Cain
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
    Am J Epidemiol 169:1124-32. 2009
    ..These methods may help resolve discrepancies between observational and randomized evidence...
  77. ncbi request reprint Drug use among female sex workers in Hanoi, Vietnam
    Trung Nam Tran
    Department of Epidemiology, University of California, Los Angeles School of Public Health, Los Angeles, CA 90095 1772, USA
    Addiction 100:619-25. 2005
    ..To describe the drug use practices among female sex workers (FSWs) in Hanoi and to identify factors associated with their drug injecting...
  78. ncbi request reprint Lack of associations between HLA class II alleles and resistance to HIV-1 infection among white, non-Hispanic homosexual men
    Chenglong Liu
    School of Public Health, University of California, Los Angeles, CA 90095 1772, USA
    J Acquir Immune Defic Syndr 37:1313-7. 2004
    ..Other genetic factors in the HLA class II-TAP region of the major histocompatibility complex might be involved...
  79. ncbi request reprint Factors associated with declining HIV testing and failure to return for results among pregnant women in Vietnam
    Thu Ha Dinh
    School of Public Health, University of California at Los Angeles, Los Angeles, CA, USA
    AIDS 19:1234-6. 2005
    ..Low educational level was associated with not returning for results. Testing programmes need to address husbands' attitudes, low education levels, and perceptions of risk...
  80. ncbi request reprint Mortality among participants in the Multicenter AIDS Cohort Study and the Women's Interagency HIV Study
    Nancy A Hessol
    Department of Medicine, University of California, San Francisco, CA 94122, USA
    Clin Infect Dis 44:287-94. 2007
    ..We examined temporal trends and risk factors for accident- and injury-related mortality among HIV-infected and -uninfected participants in the Women's Interagency HIV Study (WIHS) and the Multicenter AIDS Cohort Study (MACS)...
  81. pmc Evaluation of adherence and factors affecting adherence to combination antiretroviral therapy among White, Hispanic, and Black men in the MACS Cohort
    Debora Lee Oh
    Department of Epidemiology, School of Public Health, University of California, Los Angeles, CA 90095 1772, USA
    J Acquir Immune Defic Syndr 52:290-3. 2009
    ..This study investigated levels of adherence to antiretroviral therapy in white, Hispanic, and black men and isolated factors associated with adherence among each racial group...
  82. pmc Homeostasis of the naive CD4+ T cell compartment during aging
    Ryan D Kilpatrick
    University of California AIDS Institute and Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, 10833 Le Conte, CA 90095, USA
    J Immunol 180:1499-507. 2008
    ..Our results provide insight into naive CD4+ T cell homeostasis during aging that can be used to better understand the mechanisms that may contribute to immunosenescence within this compartment...
  83. ncbi request reprint Condom use and its correlates among female sex workers in Hanoi, Vietnam
    Trung Nam Tran
    Department of Epidemiology, UCLA School of Public Health, Los Angeles, CA 90095, USA
    AIDS Behav 10:159-67. 2006
    ..Condom promotion should focus on FSWs and their partners. Negative attitudes toward FSWs and condom promotion need to be changed to reduce stigmatization of FSWs and to make condom use a norm in the society...
  84. ncbi request reprint The HIV epidemic in China: history, response, and challenge
    Na He
    Department of Epidemiology, School of Public Health, Fudan University, Shanghai 200032, China
    Cell Res 15:825-32. 2005
    ....
  85. ncbi request reprint Use of total lymphocyte count and hemoglobin concentration for monitoring progression of HIV infection
    Bryan Lau
    Department of Epidemiology, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Acquir Immune Defic Syndr 39:620-5. 2005
    ..Prior research has demonstrated rapid declines in total lymphocyte count (TLC) and hemoglobin levels before AIDS, but the prognostic accuracy of these declines has not been examined prospectively...
  86. pmc Recreational drug use and risk of Kaposi's sarcoma in HIV- and HHV-8-coinfected homosexual men
    Chun Chao
    Department of Epidemiology and Jonsson Comprehensive Cancer Center, University of California at Los Angeles, 650 Charles E Young Drive South, Los Angeles, CA 90095, USA
    AIDS Res Hum Retroviruses 25:149-56. 2009
    ..46 (1.01-2.13)]. However, no clear dose-response relationship was observed. These findings do not support a biological association between use of these substances and KS development in HIV- and HHV-8-coinfected homosexual men...
  87. pmc Challenges in providing services in methadone maintenance therapy clinics in China: service providers' perceptions
    Chunqing Lin
    School of Public Health, University of California at Los Angeles, Los Angeles, CA 90024, USA
    Int J Drug Policy 21:173-8. 2010
    ..As of the end of November, 2008, 558 MMT clinics had been established countrywide. The objective of this study was to elucidate the difficulties and challenges as perceived by service providers working in MMT clinics...
  88. pmc Acceptance of and barriers to voluntary HIV counselling and testing among adults in Guizhou province, China
    Wei Ma
    National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    AIDS 21:S129-35. 2007
    ....
  89. pmc A comparison of voluntary counseling and testing uptake between a China CARES county and a county not designated for the china CARES program
    Wei Ma
    Chinese Center for Disease Control and Prevention, National Center for AIDS STD Control and Prevention, Beijing, China
    AIDS Patient Care STDS 22:521-33. 2008
    ..If the China CARES program is to be successful, it must implement a more effective education program and increase the acceptability of testing...
  90. ncbi request reprint MCP-1-MCP-3-Eotaxin gene cluster influences HIV-1 transmission
    William S Modi
    SAIC Frederick and the Laboratory of Genomic Diversity, National Cancer Institute, Frederick, Maryland, USA
    AIDS 17:2357-65. 2003
    ..An epidemiological analysis identified genetic variants influencing HIV-1 transmission and disease progression...
  91. pmc Evaluation of sexually transmitted diseases/human immunodeficiency virus intervention programs for sex workers in Calcutta, India
    Dwijendra Nath Gangopadhyay
    Department of Dermatology and STD, Calcutta National Medical College, Calcutta, India
    Sex Transm Dis 32:680-4. 2005
    ..The Sonagachi Project in Calcutta, India, organized sex workers to improve working conditions...
  92. doi request reprint Host genetic influences on highly active antiretroviral therapy efficacy and AIDS-free survival
    Sher L Hendrickson
    Laboratory of Genomic Diversity, National Cancer Institute, Frederick, MD 21702 1201, USA
    J Acquir Immune Defic Syndr 48:263-71. 2008
    ..27; P=0.01). ARG influence after HAART suggests residual HIV-1 replication, and spread continues even in patients successfully suppressing detectable viral RNA...
  93. pmc Effect of tuberculosis on the survival of HIV-infected men in a country with low tuberculosis incidence
    Hugo Lopez-Gatell
    Directorate of Epidemiology, Ministry of Health, Mexico, Mexico
    AIDS 22:1869-73. 2008
    ..2-4.7). Results underscore the importance of avoiding TB by using preventive interventions such as treatment of latent TB infection, particularly in populations with a large prevalence of HIV/TB co-infected individuals...
  94. pmc Lack of evidence for changing virulence of HIV-1 in North America
    Joshua T Herbeck
    University of Washington School of Medicine, Seattle, Washington, USA
    PLoS ONE 3:e1525. 2008
    ....
  95. ncbi request reprint Impact of inversion of the CD4/CD8 ratio on the natural history of HIV-1 infection
    Joseph B Margolick
    Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Acquir Immune Defic Syndr 42:620-6. 2006
    ..HIV-1 infection is characterized by an inverted CD4/CD8 T-cell ratio, but the distribution of inversions over time after seroconversion and whether delay of inversion is associated with a favorable prognosis are not known...
  96. ncbi request reprint Public health. HIV testing in China
    Zunyou Wu
    National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, PR China
    Science 312:1475-6. 2006
  97. ncbi request reprint Repeat-region polymorphisms in the gene for the dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin-related molecule: effects on HIV-1 susceptibility
    Huanliang Liu
    Department of Laboratory Medicine, University of Washington School of Medicine, Seattle, Washington 98195 8070, USA
    J Infect Dis 193:698-702. 2006
    ..5% in high-risk HIV-1-seronegative individuals vs. 27.6% in HIV-1-seropositive individuals; P=.0291). These findings suggest that DC-SIGNR polymorphisms may influence susceptibility to HIV-1...
  98. ncbi request reprint HIV infection and sexually transmitted diseases in female commercial sex workers in China
    Yanpeng Ding
    Chinese Center for Disease Control and Prevention, Beijing, China
    J Acquir Immune Defic Syndr 38:314-9. 2005
    ..Inconsistent use of condoms and a high level of STDs underscore the urgent need to implement intervention strategies and condom promotion, particularly among direct sex workers in China...
  99. ncbi request reprint Current HIV/AIDS/STI epidemic: intervention programs in Cambodia, 1993-2003
    Vonthanak Saphonn
    The National Center for HIV AIDS, Dermatology and STDs, Ministry of Health, Phnom Penh, Cambodia
    AIDS Educ Prev 16:64-77. 2004
    ..More research and prevention programs should focus on the vulnerable populations. HIV/AIDS modeling indicates that Cambodia needs to prepare for increasingly large numbers of AIDS patients who will require expensive medical care...
  100. ncbi request reprint Intravenous drug use among street-based sex workers: a high-risk behavior for HIV transmission
    Anh Tuan Nguyen
    National Institute of Hygiene and Epidemiology, Hanoi, Vietnam
    Sex Transm Dis 31:15-9. 2004
    ..5% in 1999 to 18.1% in 2000. This study examined whether injecting drug use among street-based sex workers (SSWs) in Ho Chi Minh City is a high-risk factor for HIV infection...
  101. ncbi request reprint Sexual activities of patients with STDs in the interval between noticing symptoms and presenting for treatment
    Hongjie Liu
    School of Public Health, Chinese University of Hong Kong
    AIDS Patient Care STDS 17:453-9. 2003
    ..Intervention programs including health education and condom promotion need to target both those at high risk and those at apparently lower risk...

Research Grants3

  1. INTERDISCIPLINARY TRAINING IN HIV/AIDS EPIDEMIOLOGY
    Roger Detels; Fiscal Year: 2005
    ..Trainees will be expected to publish at least one paper from their dissertation. Special efforts will be made to recruit qualified candidates from underrepresented minority groups. ..
  2. NATURAL HISTORY OF AIDS IN HOMOSEXUAL MEN
    Roger Detels; Fiscal Year: 2007
    ..With the assistance of its Community Advisory Board and its outstanding staff, the UCLA Center of the MACS is committed to maintaining the same level of commitment, leadership and follow-up of the cohort through 2009. ..