C V Desouza

Summary

Affiliation: University of Nebraska Medical Center
Country: USA

Publications

  1. pmc Pioglitazone in the treatment of type 2 diabetes: safety and efficacy review
    Cyrus V Desouza
    University of Nebraska Medical Center, Omaha, NE, USA
    Clin Med Insights Endocrinol Diabetes 3:43-51. 2010
  2. pmc Peroxisome proliferator-activated receptors as stimulants of angiogenesis in cardiovascular disease and diabetes
    Cyrus V Desouza
    University of Nebraska Medical Center, Omaha, NE, USA
    Diabetes Metab Syndr Obes 2:165-72. 2009
  3. doi request reprint Does drug therapy reverse endothelial progenitor cell dysfunction in diabetes?
    Cyrus V Desouza
    Omaha VA Medical Center, Omaha, NE, USA University of Nebraska Medical Center, Omaha, NE, USA Electronic address
    J Diabetes Complications 27:519-25. 2013
  4. doi request reprint Role of apathy in the effectiveness of weight management programmes
    C V Desouza
    Omaha VA Medical Center, Omaha, NE, USA
    Diabetes Obes Metab 14:419-23. 2012
  5. pmc Role of inflammation and insulin resistance in endothelial progenitor cell dysfunction
    Cyrus V Desouza
    University of Nebraska Medical Center, Omaha, Nebraska, USA
    Diabetes 60:1286-94. 2011
  6. doi request reprint An overview of salsalate as a potential antidiabetic therapy
    C V Desouza
    University of Nebraska Medical Center and Omaha VA Medical Center, Omaha, Nebraska 68198, USA
    Drugs Today (Barc) 46:847-53. 2010
  7. doi request reprint The effect of group clinics in the control of diabetes
    Cyrus V Desouza
    University of Nebraska Medical Center, Omaha, 68105, United States
    Prim Care Diabetes 4:251-4. 2010
  8. doi request reprint Effects of a PPAR-gamma agonist, on growth factor and insulin stimulated endothelial cells
    Cyrus V Desouza
    Omaha Veterans Affairs Medical Center, United States University of Nebraska Medical Center, United States
    Vascul Pharmacol 51:162-8. 2009
  9. ncbi request reprint Long-term effects of a PPAR-gamma agonist, pioglitazone, on neointimal hyperplasia and endothelial regrowth in insulin resistant rats
    Cyrus V Desouza
    Omaha Veterans Affairs Medical Center, Omaha, NE 68105, USA
    Vascul Pharmacol 46:188-94. 2007
  10. ncbi request reprint Neointimal hyperplasia and vascular endothelial growth factor expression are increased in normoglycemic, insulin resistant, obese fatty rats
    Cyrus V Desouza
    Research Service, Omaha Veterans Affairs Medical Center, Section of Diabetes, Endocrinology and Metabolism, University of Nebraska Medical Center, Omaha, NE 68105, USA
    Atherosclerosis 184:283-9. 2006

Collaborators

Detail Information

Publications13

  1. pmc Pioglitazone in the treatment of type 2 diabetes: safety and efficacy review
    Cyrus V Desouza
    University of Nebraska Medical Center, Omaha, NE, USA
    Clin Med Insights Endocrinol Diabetes 3:43-51. 2010
    ..Pioglitazone also has beneficial effects on lipid metabolism and cardiovascular risk. The safety and efficacy of pioglitazone including its pleotropic effects are discussed at length in this article...
  2. pmc Peroxisome proliferator-activated receptors as stimulants of angiogenesis in cardiovascular disease and diabetes
    Cyrus V Desouza
    University of Nebraska Medical Center, Omaha, NE, USA
    Diabetes Metab Syndr Obes 2:165-72. 2009
    ..This review discusses the role of PPARs in stimulating angiogenesis. It also reviews the settings in which stimulation of angiogenesis may be either beneficial or harmful...
  3. doi request reprint Does drug therapy reverse endothelial progenitor cell dysfunction in diabetes?
    Cyrus V Desouza
    Omaha VA Medical Center, Omaha, NE, USA University of Nebraska Medical Center, Omaha, NE, USA Electronic address
    J Diabetes Complications 27:519-25. 2013
    ..This review will discuss the evidence in the literature regarding the above mentioned topics...
  4. doi request reprint Role of apathy in the effectiveness of weight management programmes
    C V Desouza
    Omaha VA Medical Center, Omaha, NE, USA
    Diabetes Obes Metab 14:419-23. 2012
    ..Mental health problems such as apathy may be a major factor in patients unsuccessful in adhering to weight loss programmes. We propose that treating apathy will result in better weight loss in obese patients...
  5. pmc Role of inflammation and insulin resistance in endothelial progenitor cell dysfunction
    Cyrus V Desouza
    University of Nebraska Medical Center, Omaha, Nebraska, USA
    Diabetes 60:1286-94. 2011
    ..Modifying EPCs by a knockdown of nuclear factor-κB (NF-κB) can reverse the insulin signaling defects, improve EPC survival, and decrease neointimal hyperplasia in Zucker fatty rats postangioplasty...
  6. doi request reprint An overview of salsalate as a potential antidiabetic therapy
    C V Desouza
    University of Nebraska Medical Center and Omaha VA Medical Center, Omaha, Nebraska 68198, USA
    Drugs Today (Barc) 46:847-53. 2010
    ..Postulated mechanisms include the inhibition of nuclear factor NF-kappa-B. Discussed in this review are the efficacy, safety and mechanisms of salsalate relevant to the treatment of type 2 diabetes...
  7. doi request reprint The effect of group clinics in the control of diabetes
    Cyrus V Desouza
    University of Nebraska Medical Center, Omaha, 68105, United States
    Prim Care Diabetes 4:251-4. 2010
    ..Novel interventions are needed for long-term maintenance of diabetes control. We studied the effects of a group diabetes clinic (GDC) on diabetes control when compared to usual care with primary care providers (PCP)...
  8. doi request reprint Effects of a PPAR-gamma agonist, on growth factor and insulin stimulated endothelial cells
    Cyrus V Desouza
    Omaha Veterans Affairs Medical Center, United States University of Nebraska Medical Center, United States
    Vascul Pharmacol 51:162-8. 2009
    ..We studied the effect of pioglitazone on VEGF, FGF and insulin stimulated endothelial cells to determine if this was a mechanism of inhibition of endothelial regrowth...
  9. ncbi request reprint Long-term effects of a PPAR-gamma agonist, pioglitazone, on neointimal hyperplasia and endothelial regrowth in insulin resistant rats
    Cyrus V Desouza
    Omaha Veterans Affairs Medical Center, Omaha, NE 68105, USA
    Vascul Pharmacol 46:188-94. 2007
    ..PPAR-gamma agonists like pioglitazone decrease insulin resistance and have been shown to reduce neointimal hyperplasia in the short-term. However long-term studies on endothelial regrowth and neointimal hyperplasia have not been done...
  10. ncbi request reprint Neointimal hyperplasia and vascular endothelial growth factor expression are increased in normoglycemic, insulin resistant, obese fatty rats
    Cyrus V Desouza
    Research Service, Omaha Veterans Affairs Medical Center, Section of Diabetes, Endocrinology and Metabolism, University of Nebraska Medical Center, Omaha, NE 68105, USA
    Atherosclerosis 184:283-9. 2006
    ..We studied NH and VEGF expression in an obese, insulin resistant, but normoglycemic rat model, after carotid balloon injury...
  11. ncbi request reprint Differential effects of peroxisome proliferator activator receptor-alpha and gamma ligands on intimal hyperplasia after balloon catheter-induced vascular injury in Zucker rats
    Cyrus V Desouza
    Department of Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA
    J Cardiovasc Pharmacol Ther 8:297-305. 2003
    ..We studied the effect of fenofibrate and rosiglitazone on intimal hyperplasia in the Zucker rat, a model for insulin resistance and type 2 diabetes mellitus, following balloon catheter-induced injury...
  12. ncbi request reprint The impact of apathy on glycemic control in diabetes: a cross-sectional study
    Prasad R Padala
    Veterans Affairs Medical Center, Omaha, NE 68105, USA
    Diabetes Res Clin Pract 79:37-41. 2008
    ..The secondary objective was to determine if there was an association between clinically significant apathy and factors that affect glycemic control...