Research Topics
| Colin A DeppSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Health-related quality of life and functioning of middle-aged and elderly adults with bipolar disorderColin A Depp
Department of Psychiatry, University of California, San Diego, CA 92161, and the VA Health Services Research and Development Center for Mental Healthcare and Outcomes Research, Central Arkansas Veterans Healthcare System, USA
J Clin Psychiatry 67:215-21. 2006..Remission of bipolar disorder was associated with significant but incomplete improvement in functioning, whereas psychotic and depressive symptoms and cognitive impairment seemed to contribute to lower HRQoLF...
Building blocks of successful aging: a focus group study of older adults' perceived contributors to successful agingJennifer Reichstadt
Sam and Rose Stein Institute for Research on Aging, University of California, San Diego, San Diego, CA 92161, USA
Am J Geriatr Psychiatry 15:194-201. 2007..The purpose of this study was to solicit the opinions of older adults about factors related to successful aging using focus group methods...
Psychopathological and functional correlates of behavioral activation and avoidance in schizophreniaColin A Depp
Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
J Nerv Ment Dis 199:861-5. 2011..These results suggest that activation and avoidance may be important therapeutic targets in schizophrenia, with somewhat divergent pathways among psychopathological features to functional impairment...
Affective symptoms and intra-individual variability in the short-term course of cognitive functioning in bipolar disorderC A Depp
Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093 0664, USA
Psychol Med 42:1409-16. 2012..Key questions are whether trajectories in symptoms covary with cognitive function and whether BD is associated with increased intra-individual variability in cognitive abilities...
Meta-analysis of the association between cognitive abilities and everyday functioning in bipolar disorderColin A Depp
Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093 0603, USA
Bipolar Disord 14:217-26. 2012..The goal of this meta-analysis was to examine the magnitude of the effect of specific neurocognitive abilities on everyday functioning in bipolar disorder...
Successful cognitive agingColin A Depp
Sam and Rose Stein Institute for Research on Aging, San Diego, USA
Curr Top Behav Neurosci 10:35-50. 2012..Thus, there is a variety of recent findings providing optimism that successful cognitive aging, howsoever defined, will be attainable by more older adults in the future...
Determinants of occupational and residential functioning in bipolar disorderColin A Depp
Department of Psychiatry, University of California, San Diego, CA, United States
J Affect Disord 136:812-8. 2012..The influence of cognitive impairment and affective symptoms on these functional attainments has received little previous attention and is the focus of this study...
Establishing an implementation network: lessons learned from community-based participatory researchLaurie A Lindamer
Department of Psychiatry, University of California, San Diego, La Jolla, California, USA
Implement Sci 4:17. 2009..These partnerships provide necessary organizational support to facilitate the implementation of clinical research findings in community practice benefiting consumers, researchers, and providers...
Assessment of medication management ability in middle-aged and older adults with bipolar disorderColin A Depp
Department of Psychiatry, University of California, San Diego, CA, USA
J Clin Psychopharmacol 28:225-9. 2008..This small cross-sectional study suggests that deficits in medication management ability may be present in later-life BD. Neurocognitive deficits may be important in understanding problems with unintentional nonadherence...
Age, affective experience, and television useColin A Depp
Stein Institute for Research on Aging, University of California, San Diego, La Jolla, 92093 0664, USA
Am J Prev Med 39:173-8. 2010..The reasons for the reportedly high levels of TV watching among older adults despite its potential negative health consequences are not known...
Psychosocial interventions and medication adherence in bipolar disorderColin A Depp
Sam and Rose Stein Institute for Research on Aging, Department of Psychiatry, University of California, San Gilman Drive, 0664 La Jolla, CA 92093 0664, USA
Dialogues Clin Neurosci 10:239-50. 2008..In this review, we provide an overview of the rationale, evidence base, and major psychotherapeutic approaches in bipolar disorder, focusing on the assessment and enhancement of medication adherence...
Short-term course of neuropsychological abilities in middle-aged and older adults with bipolar disorderColin A Depp
Department of Psychiatry, University of California at San Diego, San Diego, CA 92161, USA
Bipolar Disord 10:684-90. 2008..There are few longitudinal studies of neurocognition in bipolar disorder, and the short-term course of cognitive deficits in later-life bipolar disorder is unknown...
Disability and self-management practices of people with bipolar disorder: a web-based surveyColin A Depp
Department of Psychiatry, Sam and Rose Stein Institute for Research on Aging, University of California, San Diego, La Jolla, CA 92093 0664, USA
Community Ment Health J 45:179-87. 2009..001 level. Given limitations of web-based surveys, our study underscores the substantial negative impact of bipolar disorder, along with the potential of the Internet to enhance the use of self-management strategies...
Mobile interventions for severe mental illness: design and preliminary data from three approachesColin A Depp
Department of Psychiatry, University of California, San Diego, CA, USA
J Nerv Ment Dis 198:715-21. 2010..Therefore, mobile devices seem feasible and acceptable in augmenting psychosocial interventions for severe mental illness, with future research in establishing efficacy, cost effectiveness, and ethical and safety protocols...
Social competence and observer-rated social functioning in bipolar disorderColin A Depp
Stein Institute for Research on Aging, Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0664, USA
Bipolar Disord 12:843-50. 2010..We examined performance-based and observer-based ratings of social competence and functioning and assessed the contribution of symptoms and neurocognitive ability to social functioning in bipolar disorder...
Recent advances in research on successful or healthy agingColin A Depp
Sam and Rose Stein Institute for Research on Aging, University of California at San Diego, 9500 Gilman Drive 0665, La Jolla, CA 92093 0664, USA
Curr Psychiatry Rep 9:7-13. 2007..Considerable progress has been made toward understanding possible mechanisms of successful aging through translational research. Interventions to augment healthy lifestyles have great potential to enhance global healthy aging...
Differences in clinical features and mental health service use in bipolar disorder across the lifespanColin A Depp
Department of Psychiatry, University of California, San Diego, VA San Diego Healthcare System, 9500 Gilman Dr, 0603V, San Diego, CA 92093 0603, USA
Am J Geriatr Psychiatry 13:290-8. 2005..Because of the scarcity of research in geriatric bipolar disorder, the authors examined the prevalence, clinical features, and service use of persons with bipolar disorder among older adults treated in a large public mental health system...
Successful aging: focus on cognitive and emotional healthColin Depp
Sam and Rose Stein Institute for Research on Aging, Department of Psychiatry, University of California, San Diego, La Jolla, California 92093, USA
Annu Rev Clin Psychol 6:527-50. 2010..Recent clinical trials suggest that caloric restriction, physical activity, cognitive intervention, stress reduction, and social programs may enhance cognitive and emotional health in older people...
Definitions and predictors of successful aging: a comprehensive review of larger quantitative studiesColin A Depp
Department of Psychiatry, University of California, San Diego, CA 92161, USA
Am J Geriatr Psychiatry 14:6-20. 2006..quot; Our aim was to review the literature on proportions of subjects meeting criteria and individual components of definitions of successful aging as well as correlates of these definitions...
Performance-based and subjective measures of functioning in middle-aged and older adults with bipolar disorderColin A Depp
Department of Psychiatry, University of California, San Diego VA San Diego Healthcare System, 3350 La Jolla Village Drive 116A 1, San Diego, CA 92161, USA
J Nerv Ment Dis 197:471-5. 2009..Given its relative independence from symptoms, the UPSA may be useful in gauging the effectiveness of rehabilitation for bipolar disorder...
Neurocognitive impairment in middle-aged and older adults with bipolar disorder: comparison to schizophrenia and normal comparison subjectsColin A Depp
Department of Psychiatry, University of California, San Diego, United States
J Affect Disord 101:201-9. 2007..We examined neurocognitive abilities in middle-aged and older adults with bipolar disorder to groups with schizophrenia or normal subjects, as well as the relation of neurocognition to clinical characteristics...
Relationship of the Brief UCSD Performance-based Skills Assessment (UPSA-B) to multiple indicators of functioning in people with schizophrenia and bipolar disorderBrent T Mausbach
Department of Psychiatry, University of California at San Diego, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0680, USA
Bipolar Disord 12:45-55. 2010....
Sensitivity and specificity of the UCSD Performance-based Skills Assessment (UPSA-B) for identifying functional milestones in schizophreniaBrent T Mausbach
Department of Psychiatry, University of California, San Diego, United States
Schizophr Res 132:165-70. 2011....
Measurement and predictors of resilience among community-dwelling older womenAmanda J Lamond
School of Medicine, University of California, San Diego 92093, United States
J Psychiatr Res 43:148-54. 2008..Resilience, the ability to adapt positively to adversity, may be an important factor in successful aging. However, the assessment and correlates of resilience in elderly individuals have not received adequate attention...
Association between older age and more successful aging: critical role of resilience and depressionDilip V Jeste
Stein Institute for Research on Aging, The Department of Psychiatry, and the Department of Neurosciences, University of California, San Diego, CA, USA
Am J Psychiatry 170:188-96. 2013....
Subthreshold depression and successful aging in older womenIpsit V Vahia
Department of Psychiatry, University of California, San Diego, CA, USA
Am J Geriatr Psychiatry 18:212-20. 2010....
Self-administered cognitive screening for a study of successful aging among community-dwelling seniors: a preliminary studyDavid J Moore
Department of Psychiatry, University of California, San Diego, California 92161, USA
Int J Geriatr Psychiatry 22:327-31. 2007..Yet, there are few published instruments for brief and reliable self-administered cognitive assessment that could be used in large population-based studies of community-dwelling elderly people...
Integration of the pleasant events and activity restriction models: development and validation of a "PEAR" model of negative outcomes in Alzheimer's caregiversBrent T Mausbach
Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093 0680, USA
Behav Ther 42:78-88. 2011....
Exergames for subsyndromal depression in older adults: a pilot study of a novel interventionDori Rosenberg
Joint Doctoral Program in Clinical Psychology University of California San Diego UCSD San Diego State University SDSU, San Diego, CA, USA
Am J Geriatr Psychiatry 18:221-6. 2010..The authors assessed the feasibility, acceptability, and short-term efficacy and safety of a novel intervention using exergames (entertaining video games that combine game play with exercise) for SSD in older adults...
Perspectives on schizophrenia over the lifespan: a qualitative studySally Shepherd
National Alliance on Mental Illness, San Diego Affiliate, San Diego, CA, USA
Schizophr Bull 38:295-303. 2012..Functional rehabilitation may need to be tailored to differences in perceptions of capacity for functional improvement...
Medication adherence skills training for middle-aged and elderly adults with bipolar disorder: development and pilot studyColin A Depp
Department of Psychiatry, University of California, San Diego, CA 92161, USA
Bipolar Disord 9:636-45. 2007..We developed a 12-week manualized group intervention that combined educational, motivational, medication management skills and symptom management training adapted for older adults...
Activity restriction and depression in medical patients and their caregivers: a meta-analysisBrent T Mausbach
Department of Psychiatry, University of California, San Diego, USA
Clin Psychol Rev 31:900-8. 2011..Assessment and treatment of activity restriction may be particularly helpful in preventing depression...
Bipolar disorder in middle-aged and elderly adults: is age of onset important?Colin A Depp
Department of Psychiatry, University of California, San Diego, California, USA
J Nerv Ment Dis 192:796-9. 2004..Interpretation of these findings is limited by the sample size, cross-sectional design, and a lack of brain imaging data. Further research on the clinical features and neurobiological aspects of late-life bipolar disorder is needed...
Decisional capacity to consent to research among patients with bipolar disorder: comparison with schizophrenia patients and healthy subjectsBarton W Palmer
Department of Psychiatry, University of California, San Diego, Veterans Affairs San Diego Healthcare System, Calif 92161, USA
J Clin Psychiatry 68:689-96. 2007....
Relationship between functional capacity and community responsibility in patients with schizophrenia: differences between independent and assisted living settingsBrent T Mausbach
Department of Psychiatry, University of California San Diego, La Jolla, CA 92093 0680, USA
Community Ment Health J 44:385-91. 2008..Further, among participants residing in the community, functional capacity may predict level of responsibility...
Correlates of spirituality in older womenIpsit V Vahia
Sam and Rose Stein Institute for Research on Aging, University of California, San Diego, La Jolla, 92093, USA
Aging Ment Health 15:97-102. 2011....
Psychological protective factors across the lifespan: implications for psychiatryIpsit V Vahia
Sam and Rose Stein Institute for Research on Aging, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
Psychiatr Clin North Am 34:231-48. 2011..This article reviews the definition, measurement, associations, and putative mechanisms of selected positive psychological constructs on subjective and objective indicators of health with a focus on the latter half of the lifespan...
Older adults' perspectives on successful aging: qualitative interviewsJennifer Reichstadt
University of California, San Diego, La Jolla, USA
Am J Geriatr Psychiatry 18:567-75. 2010..The purpose of this qualitative study was to obtain older adults' individual perspectives on what constitutes successful aging along with their views regarding activities and interventions to enhance its likelihood...
Specificity of cognitive and behavioral variables to positive and negative affectBrent T Mausbach
Department of Psychiatry, University of California San Diego, La Jolla, CA 92093 0680, USA
Behav Res Ther 47:608-15. 2009..If confirmed, the findings suggest the utility of focusing interventions on each of these components in the management of depressive symptoms...
Characterizing trajectories of cognitive functioning in older adults with schizophrenia: does method matter?Wesley K Thompson
Stein Center for Research on Aging, 9500 Gilman Drive, University of California San Diego, La Jolla, CA 92093 0664, USA
Schizophr Res 143:90-6. 2013....
The moderating effect of personal mastery and the relations between stress and Plasminogen Activator Inhibitor-1 (PAI-1) antigenBrent T Mausbach
Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093 0680, USA
Health Psychol 27:S172-9. 2008..e., negative life events and caregiving distress) and Plasminogen Activator Inhibitor (PAI)-1 antigen, an inhibitor of fibrinolysis implicated in the development of cardiovascular disease...
Magnitude of impairment in decisional capacity in people with schizophrenia compared to normal subjects: an overviewDilip V Jeste
Department of Psychiatry, University of California, San Diego, USA
Schizophr Bull 32:121-8. 2006....
The relationship between objectively measured sleep disturbance and dementia family caregiver distress and burdenSherry A Beaudreau
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA
J Geriatr Psychiatry Neurol 21:159-65. 2008....
Bipolar disorder in older adults: a critical reviewColin A Depp
Department of Psychiatry, University of California at San Diego, San Diego, CA 92161, USA
Bipolar Disord 6:343-67. 2004..Greater research on bipolar disorder in older people will assist in enhancing services to this group as well as inform research on bipolar disorder across the life span...
Ecological momentary assessment in aging research: a critical reviewAshley E Cain
Department of Psychiatry, University of California, San Diego UCSD, La Jolla, CA 92093 0664, USA
J Psychiatr Res 43:987-96. 2009....
Structural differentiation of self-reported depression and anxiety in late lifeSuzanne Meeks
Department of Psychological and Brain Sciences, University of Louisville, KY, USA
J Anxiety Disord 17:627-46. 2003..Instead, the broad constructs may be represented in a more complex manner among older adults, and are less easily differentiated...
Social anxiety in older adults: phenomenology, prevalence, and measurementErla Gretarsdottir
Department of Psychological and Brain Sciences, University of Louisville, Louisville, KY 40292, USA
Behav Res Ther 42:459-75. 2004..Results are discussed in terms of explanations for age differences in social anxiety, initial psychometrics of the SPAI in an older adult sample, and suggestions for future research...
Research Grants
- A Medication Adherence Intervention for Older Adults with Bipolar DisorderColin Depp; Fiscal Year: 2007....
