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| T R DemeesterSummaryAffiliation: University of Southern California Country: USA Publications
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Publications
Biology of gastroesophageal reflux disease: pathophysiology relating to medical and surgical treatmentT R Demeester
Department of Surgery, University of Southern California School of Medicine, Los Angeles 90033 4612, USA
Annu Rev Med 50:469-506. 1999..Practical concepts regarding the treatment of gastroesophageal reflux disease are developed, based on a review of studies on the natural history of the disease and the long-term outcome of therapy...- Evolving concepts of reflux: the ups and downs of the LESTom R Demeester
Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, 90033 4612, USA
Can J Gastroenterol 16:327-31. 2002..Corrective therapy requires augmentation or restoration of barrier function... - Retinoic acid receptor-alpha messenger RNA expression is increased and retinoic acid receptor-gamma expression is decreased in Barrett's intestinal metaplasia, dysplasia, adenocarcinoma sequenceR V Lord
Department of Surgery, University of Southern California Keck School of Medicine and USC/Norris Cancer Center, Los Angeles, Calif, USA
Surgery 129:267-76. 2001..These results also suggest that a cancer field is present in the esophagus in patients with cancer and that genetic alterations can precede histopathologic alterations in this disease... 
Esophagectomy for cancer in octogenariansJ Zehetner
Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Dis Esophagus 23:666-9. 2010..9 vs 59.3 months, P= 0.31 log-rank test). Esophagectomy can be performed safely in carefully selected octogenarians with good cardiac and pulmonary function. Patients should not be denied an esophagectomy based only on their age...
Long-term outcome of antireflux surgery in patients with Barrett's esophagusW L Hofstetter
Department of Surgery, Division of Thoracic and Foregut Surgery, University of Southern California, 1510 San Pablo St, Los Angeles, CA 90033-4612, USA
Ann Surg 234:532-8; discussion 538-9. 2001..Importantly, dysplasia regressed in nearly half of the patients in whom it was present before surgery, intestinal metaplasia disappeared in 14% of patients, and high-grade dysplasia and adenocarcinoma were prevented in all...- Increased c-myb mRNA expression in Barrett's esophagus and Barrett's-associated adenocarcinomaJ Brabender
Department of Biochemistry and Molecular Biology, USC Norris Comprehensive Cancer Center, University of Southern California Keck School of Medicine, 1441 Eastlake Avenue, Los Angeles, CA 90033, USA
J Surg Res 99:301-6. 2001..The genetic basis of this process is increasingly well understood, but no studies have examined the role of the transcription factor c-myb in this disease... - A new technique for measurement of pharyngeal pH: normal values and discriminating pH thresholdS Ayazi
Division of Thoracic and Foregut Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, 1510 San Pablo Street, Suite 514, Los Angeles, CA 90033, USA
J Gastrointest Surg 13:1422-9. 2009..The aim of this study was to use this probe to measure the pharyngeal pH environment in normal subjects and establish pH thresholds to identify abnormality... - The gene expression profile of cardia intestinal metaplasia is similar to that of Barrett's esophagus, not gastric intestinal metaplasiaD S Oh
Department of Surgery, University of Southern California Response Genetics Inc, Los Angeles, California 90033, USA
Dis Esophagus 24:516-22. 2011..The indistinguishable gene expression profile of CIM and BE suggests that they may share a common etiology in the majority of patients with a similar biology, and calls into question the perception that CIM is an innocuous process... - Circular stapled pyloroplasty: a fast and effective technique for pyloric disruption during esophagectomy with gastric pull-upA Oezcelik
Department of Surgery, University of Southern California, Keck School of Medicine, Los Angeles, California 90033, USA
Dis Esophagus 24:423-9. 2011..Potential advantages include the ease and simplicity of the procedure along with virtually no risk of a leak and no graft shortening. The technique is amenable to both open and minimally invasive procedures... - Risk factors and the prevalence of trocar site herniation after laparoscopic fundoplicationD J Bowrey
Department of Surgery, University of Southern California, HCC Suite 514, 1510 San Pablo St, Los Angeles, CA 90033-4612, USA
Surg Endosc 15:663-6. 2001..This method utilizes a paramedian skin incision and separate fascial incisions through anterior and posterior rectus sheathes, with retraction of the rectus abdominis muscle laterally... - Bravo capsule induction of esophageal hypercontractility and chest painC Tharavej
Division of Thoracic and Foregut Surgery, Department of Surgery, University of Southern California, Los Angeles, CA, USA
Surg Endosc 20:783-6. 2006..CONCLUSIONS: The intraesophageal Bravo capsule can cause hypertensive esophageal contractions, which may lead to chest pain... - Predictive factors of coexisting cancer in Barrett's high-grade dysplasiaC Tharavej
Division of Thoracic and Foregut Surgery, Department of Surgery, University of Southern California, Los Angeles, CA, USA
Surg Endosc 20:439-43. 2006..009). CONCLUSION: For patients with HGD, a lesion visible on endoscopy and/or HGD at multiple biopsy levels is associated with an increased risk for coexisting cancer. These patients should be considered for early esophagectomy... - Cdx-2 expression in squamous and metaplastic columnar epithelia of the esophagusD Vallbohmer
Department of Surgery, University of Southern California, Los Angeles, 90033, USA
Dis Esophagus 19:260-6. 2006..Therefore, Cdx-2 may be a potential biomarker to detect the early transition to Barrett's esophagus... - Can clinical and endoscopic findings accurately predict early-stage adenocarcinoma?G Portale
Division of Thoracic and Foregut Surgery, University of Southern California, 1510 San Pablo Street, Los Angeles, CA 90033, USA
Surg Endosc 20:294-7. 2006..Therefore, we conducted a study to determine whether symptomatic and endoscopic findings can accurately identify node-negative early-stage adenocarcinoma... - Curative resection for esophageal adenocarcinoma: analysis of 100 en bloc esophagectomiesJ A Hagen
Department of Surgery, Keck School of Medicine, University of Southern California, 1510 San Pablo St, Los Angeles, CA 90033, USA
Ann Surg 234:520-30; discussion 530-1. 2001..Local control is excellent after en bloc resection. The extent of disease associated with tumors confined to the mucosa and submucosa provides justification for more limited and less morbid resections... - En bloc esophagectomy reduces local recurrence and improves survival compared with transhiatal resection after neoadjuvant therapy for esophageal adenocarcinomaC Rizzetto
Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
J Thorac Cardiovasc Surg 135:1228-36. 2008..The aim of this study was to determine whether the benefits of an en bloc resection would extend to patients after neoadjuvant therapy... - Clinical value of endoscopy and histology in the diagnosis of duodenogastric reflux diseaseH J Stein
Department of Surgery, University of Southern California, Los Angeles 90033 4612
Surgery 112:796-803; discussion 803-4. 1992..The accuracy of these criteria was evaluated in 135 patients with nonspecific symptoms in the foregut suggestive of duodenogastric reflux and no evidence for alcohol- or drug-induced gastric mucosal injury... - Recurrence of intramucosal esophageal adenocarcinoma arising in a former esophagostomy site: a unique case reportJ M Leers
Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
Dis Esophagus 22:E17-20. 2009..Biopsy revealed an implant metastasis of esophageal adenocarcinoma. Here, we review the literature and discuss the possible etiology... - Laparoscopic ultrasonic epithelial ablation of the lower esophagus after nissen fundoplication in a porcine model: assessment of tissue damage and healing processP I Tsai
Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, USA
Am Surg 67:1178-80. 2001..No stricture formation was seen. We conclude that the CUSA technique can completely ablate Barrett's mucosa in the setting of a prior antireflux procedure. Healing with squamous mucosal regeneration is rapid and complete... - The crura and crura-sphincter pressure dynamics in patients with isolated upright and isolated supine refluxF Banki
Keck School of Medicine, University of Southern California, Los Angeles 90033, USA
Am Surg 67:1150-6. 2001..Higher crura-sphincter pressure gradient and larger-size hiatal hernias in patients with supine reflux results in pressurization of the hernia sac and subsequent reflux when these patients are in a supine position... - Predictive factors of Barrett esophagus: multivariate analysis of 502 patients with gastroesophageal reflux diseaseG M Campos
Department of Surgery, Keck School of Medicine, University of Southern California, 1441 Eastlake Ave, Suite 7418, Los Angeles, CA 90033-0804, USA
Arch Surg 136:1267-73. 2001..Elimination of reflux with an antireflux operation in patients with 1 or more of these factors may prevent the future development of BE... - Elevated body mass disrupts the barrier to gastroesophageal reflux; discussion 1018-9S A Wajed
Department of Surgery, University of Southern California, 1510 San Pablo St, Suite 514, Los Angeles, CA 90033, USA
Arch Surg 136:1014-8. 2001..CONCLUSION: The barrier to gastroesophageal reflux is rendered insufficient in patients who are overweight... - Epigenetic patterns in the progression of esophageal adenocarcinomaC A Eads
Department of Surgery, University of Southern California, Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles, CA 90089-9176, USA
Cancer Res 61:3410-8. 2001.... - Plasma DNA: a molecular marker of surgical insult and postoperative recovery in esophageal cancerF Banki
Department of Surgery, University of California, Keck School of Medicine, Los Angeles, Calif, USA
Eur Surg Res 40:273-8. 2008..To assess plasma DNA changes intraoperatively, to relate plasma DNA to the magnitude of the surgical insult and to monitor the changes during the postoperative recovery period... - Esophageal adenocarcinoma in patients < or = 50 years old: delayed diagnosis and advanced disease at presentationG Portale
Division of Thoracic and Foregut Surgery, University of Southern California, Los Angeles, California, USA
Am Surg 70:954-8. 2004..With appropriate aggressive treatment, survival is similar. Liberal use of endoscopy and aggressive diagnostic approach are paramount in young patients with dysphagia/symptoms of gastroesophageal reflux disease (GERD)... - The safety and usefulness of endoscopy for evaluation of the graft and anastomosis early after esophagectomy and reconstructionM S Maish
Department of Surgery, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA
Surg Endosc 19:1093-102. 2005..CONCLUSION: Endoscopy early after esophagectomy is safe and provides accurate and reliable identification of graft ischemia that can be used to guide the treatment of these patients... - Upregulation of ornithine decarboxylase mRNA expression in Barrett's esophagus and Barrett's-associated adenocarcinomaJ Brabender
Department of Biochemistry and Molecular Biology/Norris Comprehensive Cancer Research Center, University of Southern California Keck School of Medicine, Los Angeles, USA
J Gastrointest Surg 5:174-81; discussion 182. 2001..early event in the development and progression of Barrett's-associated adenocarcinoma of the esophagus, and they suggest that high ODC mRNA expression levels may be a clinically useful biomarker for the detection of occult adenocarcinoma.. - Etiology of intestinal metaplasia at the gastroesophageal junctionN S Balaji
Department of Surgery, Keck School of Medicine, University of Southern California, 1510 San Pablo Street, 514, Los Angeles, CA 90033, USA
Surg Endosc 17:43-8. 2003..A Barrett's staining pattern was associated with objective evidence of gastroesophageal reflux and the absence of H. pylori, suggesting that cytokeratin 7/20 immunostaining is useful to determine the likely etiology of CIM... - Surgical therapy for Barrett's esophagus: prevention, protection and excisionT R Demeester
Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, USA. surgery.hsc.usc.edu
Dis Esophagus 15:109-16. 2002 - Pathologic duodenogastric reflux associated with persistence of symptoms after cholecystectomyP Wilson
Department of Surgery, Creighton University School of Medicine, Omaha, NE 68131, USA
Surgery 117:421-8. 1995..The aim of this study was to determine whether increased duodenogastric reflux contributes to postcholecystectomy symptoms... - Redefining gastroesophageal reflux (GER)N S Balaji
Department of Surgery, University of Southern California, 1510 San Pablo Street, Los Angeles, CA 90033, USA
Surg Endosc 17:1380-5. 2003..The additional information provided by impedance technology is likely to have a major impact on the understanding and clinical management of patients with gastroesophageal reflux disease (GERD)... - Fibrovascular polyp of the esophagus requiring esophagectomyS Kanaan
University of Southern California, Department of Cardiothoracic Surgery, Los Angeles, California 90033, USA
Dis Esophagus 20:453-4. 2007..Treatment is surgical. Only four cases in the literature underwent esophagectomy for removal. We present a female patient with a fibrovascular polyp of the esophagus who required a transhiatal esophagectomy to safely remove this mass... - Endoscopic augmentation of the cardia with a biocompatible injectable polymer (Enteryx) in a porcine modelR J Mason
Center for Heartburn and Esophageal Disorders, Midway Hospital Medical Center, 5901 West Olympic Boulevard, Suite 101, Los Angeles, CA 90036, USA
Surg Endosc 16:386-91. 2002..The aim of the study was to demonstrate the feasibility, durability, safety, and antireflux efficacy following augmentation of the cardia with a biocompatible injectable polymer (Enteryx)... - DNA methylation: an alternative pathway to cancerS A Wajed
Department of Surgery, University of Southern California School of Medicine, Los Angeles, California 90033, USA
Ann Surg 234:10-20. 2001.... - Surgical management of hypertensive lower esophageal sphincter with dysphagia or chest painAnand P Tamhankar
Department of Surgery, University of Southern California, Los Angeles, California 90033, USA
J Gastrointest Surg 7:990-6; discussion 996. 2003..A myotomy with partial fundoplication for isolated hypertensive LES relieves dysphagia and chest pain suggesting a primary sphincter dysfunction... - The impact of reflux composition on mucosal injury and esophageal functionDaniel S Oh
Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
J Gastrointest Surg 10:787-96; discussion 796-7. 2006..This suggests that composition of gastric juice is the primary determinant of inflammatory mucosal injury and subsequent loss of esophageal function... - Antireflux surgery normalizes cyclooxygenase-2 expression in squamous epithelium of the distal esophagusDaniel Vallbohmer
Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Am J Gastroenterol 101:1458-66. 2006..Further, we hypothesized that Cox-2 expression in the squamous mucosa would be reduced following the elimination of reflux with an antireflux operation... - Physiologic mechanism and preoperative prediction of new-onset dysphagia after laparoscopic Nissen fundoplicationDennis Blom
Division of Thoracic/Foregut Surgery, Department of Surgery, University of Southern California, Los Angeles, CA 9033, USA
J Gastrointest Surg 6:22-7; discussion 27-8. 2002..Patients with a normal LES or high mean LES pressures are at increased risk for developing this complication and should be informed of this before laparoscopic Nissen fundoplication... - Gastric electrical stimulation: an alternative surgical therapy for patients with gastroparesisRodney J Mason
Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles 90033, USA
Arch Surg 140:841-6; discussion 847-8. 2005..Gastric electrical stimulation is an alternative to gastrectomy in patients with refractory gastroparesis... - The duodenal switch operation for the treatment of morbid obesityGary J Anthone
Department of Surgery, University of Southerm California Keck School of Medicine, Los Angeles, CA 90033 42, USA
Ann Surg 238:618-27; discussion 627-8. 2003..To determine the safety and efficacy of the duodenal switch procedure as surgical treatment of morbid obesity... - Cardiac mucosa in the remnant esophagus after esophagectomy is an acquired epithelium with Barrett's-like featuresReginald V N Lord
Department of Surgery, University of Southern California Keck School of Medicine, Los Angeles, Calif, USA
Surgery 136:633-40. 2004..These findings are applicable to the development of similar changes at the gastroesophageal junction... - Microvasive gastric stapler: the device, technique, and preclinical resultsTom R Demeester
Department of Surgery, Keck School of Medicine, University of Southern California, 1510 San Pablo Street, Suite 514, Los Angeles, CA 90033-4612, USA
Gastrointest Endosc Clin N Am 13:117-33, x. 2003..The experimental development of an intraluminal transgastric valvuloplasty is discussed, and comments are made about the future role of endoscopic repairs... - Preoperative lower esophageal sphincter pressure affects outcome of laparoscopic esophageal myotomy for achalasiaMustafa A Arain
Department of Surgery, Division of Thoracic and Foregut Surgery, Keck School of Medicine, University of Southern California, 1510 San Pablo Street, Suite 514, Los Angeles, CA 90033, USA
J Gastrointest Surg 8:328-34. 2004..Ninety-four percent of patients are satisfied with their surgical myotomy for achalasia. By physician assessment dysphagia was resolved in 77% of patients. A high LES resting pressure before surgery predicted resolution of dysphagia... - Excellent quality of life after Nissen fundoplication depends on successful elimination of reflux symptoms and not the invasiveness of the surgical approachChristopher G Streets
Department of Surgery, University of Southern California, Los Angeles, USA
Ann Thorac Surg 74:1019-24; discussion 1024-5. 2002..These findings support the continued use of a transthoracic antireflux procedure in patients with advanced gastroesophageal reflux disease... - Absence of gastroesophageal reflux disease in a majority of patients taking acid suppression medications after Nissen fundoplicationReginald V N Lord
Department of Surgery, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA
J Gastrointest Surg 6:3-9; discussion 10. 2002..Because of the limited predictive power of symptoms, objective evidence of reflux disease should be obtained before prescribing acid suppression medication for patients who have undergone antireflux surgery... - The hypertensive lower esophageal sphincter: a motility disorder with manometric features of outflow obstructionInes Gockel
Department of Surgery, University of Southern California Keck School of Medicine, Los Angeles, California, USA
J Gastrointest Surg 7:692-700. 2003..Patients with HTLES have significantly elevated intrabolus and residual relaxation pressures on liquid boluses, suggesting that outflow obstruction is present... - Clinical biology and surgical therapy of intramucosal adenocarcinoma of the esophagusDaniel S Oh
Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
J Am Coll Surg 203:152-61. 2006..A vagal-sparing technique had less morbidity than other forms of resection and no mortality. Survival after all types of resection was similar. Outcomes of endoscopic techniques should be compared with this benchmark... - Reduction of interleukin 8 gene expression in reflux esophagitis and Barrett's esophagus with antireflux surgeryDaniel S Oh
Department of Cardiothoracic Surgery, University of Southern California, 1510 San Pablo Street, Los Angeles, CA 90033, USA
Arch Surg 142:554-9; discussion 559-60. 2007..Chronic inflammation of esophageal mucosa secondary to refluxed gastric juice increases gene expression of interleukin 8 (IL-8). Antireflux surgery can reduce this overexpression... - High intraepithelial eosinophil counts in esophageal squamous epithelium are not specific for eosinophilic esophagitis in adultsSonali Rodrigo
Department of Surgical Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
Am J Gastroenterol 103:435-42. 2008..This is based on data that the number of intraepithelial eosinophils in gastroesophageal reflux disease (GERD) is less than 20/hpf. This study tests this belief... - Ambulatory 24-hour esophageal pH monitoring: why, when, and what to doChristopher G Streets
Department of Surgery, Keck School of Medicine, University of Southern California, 1510 San Pablo Street, Suite 514, Los Angeles CA, USA
J Clin Gastroenterol 37:14-22. 2003..The composite score has been shown to be the most reliable measurement of a therapeutic acid suppression regimen or an effective antireflux operation... - Use of a magnetic sphincter for the treatment of GERD: a feasibility studyRobert A Ganz
Minnesota Gastroenterology, Plymouth, Minnesota 55446, USA
Gastrointest Endosc 67:287-94. 2008..We introduced a new device to treat GERD: biomechanical augmentation of the lower esophageal sphincter (LES) by use of a magnetic reinforcing appliance... - Towards the molecular characterization of disease: comparison of molecular and histological analysis of esophageal epitheliaDaniel Vallbohmer
Department of Surgery, University of Southern California, Los Angeles, CA, USA
J Gastrointest Surg 11:1095-104. 2007..When differences occur, it is unclear whether this effect is due to intraobserver variability in pathological diagnosis or to a genuine difference between gene expression and histopathology... - Response of the lower esophageal sphincter to gastric distention by carbonated beveragesNahid Hamoui
Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
J Gastrointest Surg 10:870-7. 2006..Carbonated beverages, but not tap water, reduce the strength of the lower esophageal sphincter. This may be relevant to the pathogenesis of gastroesophageal reflux disease, especially in Western society... - Barrett's esophagus can and does regress after antireflux surgery: a study of prevalence and predictive featuresRichard R Gurski
Department of Surgery, Division of Thoracic and Foregut Surgery, University of Southern California, Los Angeles, CA 90033, USA
J Am Coll Surg 196:706-12; discussion 712-3. 2003..Regression is dependent on the length of the columnar-lined esophagus and time of followup after antireflux surgery... - Manometry of the lower esophageal sphincter: inter- and intraindividual variability of slow motorized pull-through versus station pull-through manometryGuilherme M R Campos
Department of Surgery, University of Southern California Keck School of Medicine, Los Angeles, California 90033-4612, USA
Dig Dis Sci 48:1057-61. 2003.... - Postprandial acid reflux is reduced by delayed gastric emptyingYoshinori Yamashita
Department of Surgery, Hiroshima City Asa Hospital, Hiroshima, Japan
J Smooth Muscle Res 39:87-93. 2003..05). In patient with abnormal acid exposure but normal % PRT on 24 h esophageal pH monitoring, gastric emptying may be delayed... - Prevalence and risk factors for ischemia, leak, and stricture of esophageal anastomosis: gastric pull-up versus colon interpositionJohn W Briel
Department of Surgery, Keck School of Medicine, University of Southern California, 1510 San Pablo Street, Los Angeles, CA 90033, USA
J Am Coll Surg 198:536-41; discussion 541-2. 2004..Anastomotic leak and strictures are more common and the strictures are more severe after gastric pull-up compared with colon interposition. Dilatation is a safe and effective treatment... - Increased acid exposure in patients with gastroesophageal reflux disease influences cyclooxygenase-2 gene expression in the squamous epithelium of the lower esophagusNahid Hamoui
Department of Surgery, Division of Thoracic and Foregut Surgery, University of Southern California, Los Angeles 90033, USA
Arch Surg 139:712-6; discussion 716-7. 2004..The changes in gene expression occur before any metaplastic changes in the tissue are apparent, and may in the future be useful in predicting which patients will progress through a metaplasia-dysplasia carcinoma sequence... - Omeprazole does not reduce gastroesophageal reflux: new insights using multichannel intraluminal impedance technologyAnand P Tamhankar
Department of Surgery, University of Southern California, Los Angeles, California, USA
J Gastrointest Surg 8:890-7; discussion 897-8. 2004..These observations may explain the persistence of symptoms and emergence of mucosal injury white on proton pump inhibitor therapy... - Editorial comment: The short esophagus: going, going, gone?Steven R Demeester
Surgery 133:364-7. 2003 - Barrett's esophagus in females: a comparative analysis of risk factors in females and malesFarzaneh Banki
Department of Surgery and Cardiothoracic Surgery, Keck School of Medicine, The University of Southern California, Los Angeles, California, USA
Am J Gastroenterol 100:560-7. 2005..Esophageal bilirubin exposure is the major risk factor for the presence of Barrett's in patients with reflux disease... - Comparison of the clinical and histological characteristics and survival of distal esophageal-gastroesophageal junction adenocarcinoma in patients with and without barrett mucosaGiuseppe Portale
Division of Thoracic and Foregut Surgery, University of Southern California, Los Angeles, CA 90033, USA
Arch Surg 140:570-4; discussion 574-5. 2005..This suggests the possibility that tumors without Barrett mucosa are not of a different origin, but rather are larger tumors that may have overgrown areas of Barrett mucosa... - Quantitative, tissue-specific analysis of cyclooxygenase gene expression in the pathogenesis of Barrett's adenocarcinomaHidekazu Kuramochi
From the Department of Biochemistry and Molecular Biology, USC/Norris Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
J Gastrointest Surg 8:1007-16; discussion 1016-7. 2004..These results confirm the important role of Cox-2 amplification in the pathogenesis of esophageal adenocarcinoma, but the unexpected down-regulation of Cox-1 raises questions about its role in carcinogenesis... - Cytokeratin and DAS-1 immunostaining reveal similarities among cardiac mucosa, CIM, and Barrett's esophagusSteven R Demeester
Department of Cardiothoracic Surgery, The University of Southern California, Keck School of Medicine, Los Angeles, USA
Am J Gastroenterol 97:2514-23. 2002..This suggests that cardiac mucosa, like Barrett's, may be acquired. Likewise, immunostaining similarities between CIM and Barrett's biopsies point to the possibility of a reflux etiology for CIM in some patients... - Vagal-sparing esophagectomy: a more physiologic alternativeFarzaneh Banki
Department of Surgery, University of Southern California, Los Angeles, California 90033, USA
Ann Surg 236:324-35; discussion 335-6. 2002..It is an ideal procedure for patients with end-stage benign disease, Barrett's esophagus with high-grade dysplasia, or esophageal carcinoma limited to the lamina propria... - Vascular endothelial growth factor and basic fibroblast growth factor expression in esophageal adenocarcinoma and Barrett esophagusReginald V N Lord
Department of Surgery and Cardiothoracic Surgery, University of Southern California Keck School of Medicine, Los Angeles, USA
J Thorac Cardiovasc Surg 125:246-53. 2003..Basic fibroblast growth factor protein expression pattern is similar to the messenger RNA expression pattern, but unlike the messenger RNA findings, vascular endothelial growth factor protein expression is strongest in goblet cells...