Steven DeMeester

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. ncbi request reprint The impact of reflux composition on mucosal injury and esophageal function
    Daniel S Oh
    Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    J Gastrointest Surg 10:787-96; discussion 796-7. 2006
  2. ncbi request reprint Colon interposition following esophagectomy
    S R Demeester
    Department of Cardiothoracic Surgery, The University of Southern California Keck School of Medicine, Los Angeles, CA, USA
    Dis Esophagus 14:169-72. 2001
  3. ncbi request reprint Adenocarcinoma of the esophagus and cardia: a review of the disease and its treatment
    Steven R Demeester
    Department of Cardiothoracic Surgery, The University of Southern California, Keck School of Medicine, 1510 San Pablo Street, Suite 514, Los Angeles, California, 90033, USA
    Ann Surg Oncol 13:12-30. 2006
  4. ncbi request reprint Endoscopic mucosal resection and vagal-sparing esophagectomy for high-grade dysplasia and adenocarcinoma of the esophagus
    Steven R Demeester
    Department of Cardiothoracic Surgery, The University of Southern California, Keck School of Medicine, Los Angeles, California 90033, USA
    Semin Thorac Cardiovasc Surg 17:320-5. 2005
  5. ncbi request reprint Invited commentary. Surgical correction of a hernia has to be identified in the early postoperative period, regardless of symptoms
    Steven DeMeester
    Department of Cardiothoracic Surgery, The University of Southern California, 1510 San Pablo St, no 514, Los Angeles CA90033, USA
    Ann Thorac Surg 84:1852-3. 2007
  6. doi request reprint New options for the therapy of Barrett's high-grade dysplasia and intramucosal adenocarcinoma: endoscopic mucosal resection and ablation versus vagal-sparing esophagectomy
    Steven R Demeester
    Department of Cardiothoracic Surgery, The University of Southern California, Los Angeles, California 90033, USA
    Ann Thorac Surg 85:S747-50. 2008
  7. doi request reprint Invited commentary
    Steven R Demeester
    Department of Cardiothoracic Surgery, University of Southern California, 1510 San Pablo St, Suite 514, Los Angeles, CA90033, USA
    Ann Thorac Surg 86:440. 2008
  8. doi request reprint Vagal-sparing esophagectomy: is it a useful addition?
    Steven R Demeester
    Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Ann Thorac Surg 89:S2156-8. 2010
  9. doi request reprint Evaluation and treatment of superficial esophageal cancer
    Steven R Demeester
    Department of Cardiothoracic Surgery, The University of Southern California, Los Angeles, CA 90033, USA
    J Gastrointest Surg 14:S94-100. 2010
  10. doi request reprint Columnar-lined esophagus without intestinal metaplasia has no proven risk of adenocarcinoma
    Parakrama Chandrasoma
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Am J Surg Pathol 36:1-7. 2012

Collaborators

Detail Information

Publications53

  1. ncbi request reprint The impact of reflux composition on mucosal injury and esophageal function
    Daniel S Oh
    Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    J Gastrointest Surg 10:787-96; discussion 796-7. 2006
    ..This suggests that composition of gastric juice is the primary determinant of inflammatory mucosal injury and subsequent loss of esophageal function...
  2. ncbi request reprint Colon interposition following esophagectomy
    S R Demeester
    Department of Cardiothoracic Surgery, The University of Southern California Keck School of Medicine, Los Angeles, CA, USA
    Dis Esophagus 14:169-72. 2001
  3. ncbi request reprint Adenocarcinoma of the esophagus and cardia: a review of the disease and its treatment
    Steven R Demeester
    Department of Cardiothoracic Surgery, The University of Southern California, Keck School of Medicine, 1510 San Pablo Street, Suite 514, Los Angeles, California, 90033, USA
    Ann Surg Oncol 13:12-30. 2006
    ....
  4. ncbi request reprint Endoscopic mucosal resection and vagal-sparing esophagectomy for high-grade dysplasia and adenocarcinoma of the esophagus
    Steven R Demeester
    Department of Cardiothoracic Surgery, The University of Southern California, Keck School of Medicine, Los Angeles, California 90033, USA
    Semin Thorac Cardiovasc Surg 17:320-5. 2005
    ..A vagal-sparing esophagectomy accomplishes the goal of removing the diseased esophagus while minimizing the physiologic impact of an esophagectomy in patients with early-stage esophageal cancer...
  5. ncbi request reprint Invited commentary. Surgical correction of a hernia has to be identified in the early postoperative period, regardless of symptoms
    Steven DeMeester
    Department of Cardiothoracic Surgery, The University of Southern California, 1510 San Pablo St, no 514, Los Angeles CA90033, USA
    Ann Thorac Surg 84:1852-3. 2007
  6. doi request reprint New options for the therapy of Barrett's high-grade dysplasia and intramucosal adenocarcinoma: endoscopic mucosal resection and ablation versus vagal-sparing esophagectomy
    Steven R Demeester
    Department of Cardiothoracic Surgery, The University of Southern California, Los Angeles, California 90033, USA
    Ann Thorac Surg 85:S747-50. 2008
  7. doi request reprint Invited commentary
    Steven R Demeester
    Department of Cardiothoracic Surgery, University of Southern California, 1510 San Pablo St, Suite 514, Los Angeles, CA90033, USA
    Ann Thorac Surg 86:440. 2008
  8. doi request reprint Vagal-sparing esophagectomy: is it a useful addition?
    Steven R Demeester
    Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Ann Thorac Surg 89:S2156-8. 2010
    ..Given these advantages, a vagal-sparing esophagectomy should be the preferred method of esophageal resection in appropriate patients...
  9. doi request reprint Evaluation and treatment of superficial esophageal cancer
    Steven R Demeester
    Department of Cardiothoracic Surgery, The University of Southern California, Los Angeles, CA 90033, USA
    J Gastrointest Surg 14:S94-100. 2010
    ..The evaluation and treatment of these superficial cancers differs from local and regionally advanced lesions...
  10. doi request reprint Columnar-lined esophagus without intestinal metaplasia has no proven risk of adenocarcinoma
    Parakrama Chandrasoma
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Am J Surg Pathol 36:1-7. 2012
    ..Inadequate sampling is a powerful reason why the near absolute association between intestinal metaplasia and adenocarcinoma is not seen in some studies...
  11. doi request reprint The dilated distal esophagus: a new entity that is the pathologic basis of early gastroesophageal reflux disease
    Parakrama Chandrasoma
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Am J Surg Pathol 35:1873-81. 2011
    ..Its recognition allows for accurate and evidence-based interpretation of biopsies from this region and removes the present confusion and permits the development of a reproducible pathologic diagnostic method...
  12. ncbi request reprint Modern 5-year survival of resectable esophageal adenocarcinoma: single institution experience with 263 patients
    Giuseppe Portale
    Division of Thoracic and Foregut Surgery, University of Southern California, Los Angeles, CA 90033, USA
    J Am Coll Surg 202:588-96; discussion 596-8. 2006
    ..Epidemiologic and clinical changes over the past decade indicate that these assumptions should be reevaluated. The aim of this study was to assess the modern outcomes of esophagectomy for adenocarcinoma...
  13. ncbi request reprint Increasing cyclooxygenase-2 (cox-2) gene expression in the progression of Barrett's esophagus to adenocarcinoma correlates with that of Bcl-2
    Daisuke Shimizu
    Department of Biochemistry and Molecular Biology, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA 90033, USA
    Int J Cancer 119:765-70. 2006
    ..0053, p = 0.0220) and adenocarcinoma (p < 0.0001, p < 0.0001) compared to squamous epithelium or reflux-esophagitis. Furthermore, there is a significant correlation between these two genes, especially in carcinoma (p < 0.0001)...
  14. doi request reprint The number of lymph nodes removed predicts survival in esophageal cancer: an international study on the impact of extent of surgical resection
    Christian G Peyre
    Department of Surgery, Keck School of Medicine at the University of Southern California, Los Angeles, CA, USA
    Ann Surg 248:549-56. 2008
    ..Surveillance, Epidemiology and End Results (SEER) data indicate that number of lymph nodes removed impacts survival in gastric cancer. Our aim was to study this relationship in esophageal cancer...
  15. ncbi request reprint Increased CDX2 and decreased PITX1 homeobox gene expression in Barrett's esophagus and Barrett's-associated adenocarcinoma
    Reginald V N Lord
    Department of Surgery, University of Southern California Keck School of Medicine Norris Comprehensive Cancer Center, Los Angeles, CA, USA
    Surgery 138:924-31. 2005
    ..This study was undertaken to investigate the expression pattern of these critical morphogenesis genes in the Barrett's multistage carcinogenesis model...
  16. ncbi request reprint Antireflux surgery normalizes cyclooxygenase-2 expression in squamous epithelium of the distal esophagus
    Daniel Vallbohmer
    Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Am J Gastroenterol 101:1458-66. 2006
    ..Further, we hypothesized that Cox-2 expression in the squamous mucosa would be reduced following the elimination of reflux with an antireflux operation...
  17. ncbi request reprint Clinical biology and surgical therapy of intramucosal adenocarcinoma of the esophagus
    Daniel S Oh
    Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    J Am Coll Surg 203:152-61. 2006
    ..Acceptance of these alternative therapies requires an understanding of the clinical biology of IMC and the results of surgical resection modified for treatment of early disease...
  18. ncbi request reprint EMR for intramucosal adenocarcinoma of the esophagus: does one size fit all?
    Steven R Demeester
    Gastrointest Endosc 65:14-5. 2007
  19. ncbi request reprint Reduction of interleukin 8 gene expression in reflux esophagitis and Barrett's esophagus with antireflux surgery
    Daniel S Oh
    Department of Cardiothoracic Surgery, University of Southern California, 1510 San Pablo Street, Los Angeles, CA 90033, USA
    Arch Surg 142:554-9; discussion 559-60. 2007
    ..Chronic inflammation of esophageal mucosa secondary to refluxed gastric juice increases gene expression of interleukin 8 (IL-8). Antireflux surgery can reduce this overexpression...
  20. ncbi request reprint Vagal-sparing esophagectomy: the ideal operation for intramucosal adenocarcinoma and barrett with high-grade dysplasia
    Christian G Peyre
    Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Ann Surg 246:665-71; discussion 671-4. 2007
    ..Our aim was to compare outcome of vagal-sparing esophagectomy with transhiatal and en bloc esophagectomy in patients with intramucosal adenocarcinoma or high-grade dysplasia...
  21. doi request reprint The location of intestinal metaplasia within a columnar-lined esophagus
    Steven R Demeester
    Am J Gastroenterol 103:250-1. 2008
  22. doi request reprint Circumferential ablation of Barrett's esophagus that contains high-grade dysplasia: a U.S. Multicenter Registry
    Robert A Ganz
    Minnesota Gastroenterology, Plymouth, Minnesota 55446, USA
    Gastrointest Endosc 68:35-40. 2008
    ..The management strategies for Barrett's esophagus (BE) that contains high-grade dysplasia (HGD) include intensive endoscopic surveillance, photodynamic therapy, thermal ablation, EMR, and esophagectomy...
  23. ncbi request reprint Vascular endothelial growth factor and basic fibroblast growth factor expression in esophageal adenocarcinoma and Barrett esophagus
    Reginald V N Lord
    Department of Surgery and Cardiothoracic Surgery, University of Southern California Keck School of Medicine, Los Angeles, USA
    J Thorac Cardiovasc Surg 125:246-53. 2003
    ....
  24. ncbi request reprint Survivin, a potential biomarker in the development of Barrett's adenocarcinoma
    Daniel Vallbohmer
    Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, USA
    Surgery 138:701-6; discussion 706-7. 2005
    ..The aim of this study was to measure survivin gene expression in normal squamous/columnar epithelium and in the various stages of development of Barrett's adenocarcinoma...
  25. ncbi request reprint Surgical therapy for Barrett's esophagus
    Carl Christian A Jackson
    Department of Surgery, The University of Southern California, Keck School of Medicine, 1510 San Pablo Street, Suite 514, Los Angeles, CA 90033, USA
    Thorac Surg Clin 15:429-36. 2005
    ..It is only with excellent control of reflux that any differences in the risk of progression to dysplasia and cancer become apparent, and significant, between medically and surgically treated patients...
  26. ncbi request reprint Preoperative lower esophageal sphincter pressure affects outcome of laparoscopic esophageal myotomy for achalasia
    Mustafa A Arain
    Department of Surgery, Division of Thoracic and Foregut Surgery, Keck School of Medicine, University of Southern California, 1510 San Pablo Street, Suite 514, Los Angeles, CA 90033, USA
    J Gastrointest Surg 8:328-34. 2004
    ..Ninety-four percent of patients are satisfied with their surgical myotomy for achalasia. By physician assessment dysphagia was resolved in 77% of patients. A high LES resting pressure before surgery predicted resolution of dysphagia...
  27. ncbi request reprint Barrett's esophagus
    Jeffrey H Peters
    Department of Surgery, University of Southern California, Los Angeles, California, USA
    J Gastrointest Surg 8:1-17. 2004
  28. ncbi request reprint Surgical management of hypertensive lower esophageal sphincter with dysphagia or chest pain
    Anand P Tamhankar
    Department of Surgery, University of Southern California, Los Angeles, California 90033, USA
    J Gastrointest Surg 7:990-6; discussion 996. 2003
    ..A myotomy with partial fundoplication for isolated hypertensive LES relieves dysphagia and chest pain suggesting a primary sphincter dysfunction...
  29. ncbi request reprint Lymph node involvement in esophageal adenocarcinoma: if you see one, have you seen them all?
    Steven R Demeester
    J Thorac Cardiovasc Surg 126:947-9. 2003
  30. ncbi request reprint Increasing esophageal length: a comparison of laparoscopic versus transthoracic esophageal mobilization with and without vagal trunk division in pigs
    Steven R Demeester
    Department of Cardiothoracic Surgery, The University of Southern California, Keck School of Medicine, Los Angeles, CA, USA
    J Am Coll Surg 197:558-64. 2003
    ..The aim of this study was to compare the increase in esophageal length achievable with laparoscopic and transthoracic esophageal mobilization in pigs, and to assess the impact of vagal trunk division on esophageal length...
  31. ncbi request reprint Barrett's esophagus can and does regress after antireflux surgery: a study of prevalence and predictive features
    Richard R Gurski
    Department of Surgery, Division of Thoracic and Foregut Surgery, University of Southern California, Los Angeles, CA 90033, USA
    J Am Coll Surg 196:706-12; discussion 712-3. 2003
    ..To investigate the factors leading to histologic regression of metaplastic and dysplastic Barrett's esophagus (BE)...
  32. ncbi request reprint Excellent quality of life after Nissen fundoplication depends on successful elimination of reflux symptoms and not the invasiveness of the surgical approach
    Christopher G Streets
    Department of Surgery, University of Southern California, Los Angeles, USA
    Ann Thorac Surg 74:1019-24; discussion 1024-5. 2002
    ....
  33. ncbi request reprint Cytokeratin and DAS-1 immunostaining reveal similarities among cardiac mucosa, CIM, and Barrett's esophagus
    Steven R Demeester
    Department of Cardiothoracic Surgery, The University of Southern California, Keck School of Medicine, Los Angeles, USA
    Am J Gastroenterol 97:2514-23. 2002
    ..We hypothesized that the immunostaining patterns of these foregut tissues would provide insight into the nature and etiology of cardiac mucosa and CIM...
  34. pmc Vagal-sparing esophagectomy: a more physiologic alternative
    Farzaneh Banki
    Department of Surgery, University of Southern California, Los Angeles, California 90033, USA
    Ann Surg 236:324-35; discussion 335-6. 2002
    ..To evaluate the function of the vagal nerves and the gastric reservoir after vagal-sparing esophagectomy...
  35. ncbi request reprint Physiologic mechanism and preoperative prediction of new-onset dysphagia after laparoscopic Nissen fundoplication
    Dennis Blom
    Division of Thoracic Foregut Surgery, Department of Surgery, University of Southern California, Los Angeles, CA 9033, USA
    J Gastrointest Surg 6:22-7; discussion 27-8. 2002
    ..Patients with a normal LES or high mean LES pressures are at increased risk for developing this complication and should be informed of this before laparoscopic Nissen fundoplication...
  36. ncbi request reprint Prevalence and risk factors for ischemia, leak, and stricture of esophageal anastomosis: gastric pull-up versus colon interposition
    John W Briel
    Department of Surgery, Keck School of Medicine, University of Southern California, 1510 San Pablo Street, Los Angeles, CA 90033, USA
    J Am Coll Surg 198:536-41; discussion 541-2. 2004
    ..Reports of esophageal anastomotic complications often involve more gastric than colonic reconstructions and are incomplete because of fragmented followup by physicians unfamiliar with the surgical procedure...
  37. ncbi request reprint Absence of gastroesophageal reflux disease in a majority of patients taking acid suppression medications after Nissen fundoplication
    Reginald V N Lord
    Department of Surgery, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA
    J Gastrointest Surg 6:3-9; discussion 10. 2002
    ..Because of the limited predictive power of symptoms, objective evidence of reflux disease should be obtained before prescribing acid suppression medication for patients who have undergone antireflux surgery...
  38. pmc The mutagenic potential of duodenoesophageal reflux
    Jorg Theisen
    Department of Surgery, Klinikum rechts der Isar, Technische Universitaet Muenchen, Munich, Germany
    Ann Surg 241:63-8. 2005
    ..Despite this link, little is known about the mutagenic potential of refluxed material on the esophageal mucosa. We hypothesize that the reflux of gastric and duodenal content causes mutations in esophageal mucosa in vivo...
  39. ncbi request reprint Barrett's esophagus in females: a comparative analysis of risk factors in females and males
    Farzaneh Banki
    Department of Surgery and Cardiothoracic Surgery, Keck School of Medicine, The University of Southern California, Los Angeles, California, USA
    Am J Gastroenterol 100:560-7. 2005
    ..The reason for this disparity is unknown. The aim of this study was to determine the factors related to Barrett's in females...
  40. ncbi request reprint Comparison of the clinical and histological characteristics and survival of distal esophageal-gastroesophageal junction adenocarcinoma in patients with and without barrett mucosa
    Giuseppe Portale
    Division of Thoracic and Foregut Surgery, University of Southern California, Los Angeles, CA 90033, USA
    Arch Surg 140:570-4; discussion 574-5. 2005
    ..This has led to the belief that patients with and without Barrett mucosa may represent 2 distinct cancer types...
  41. ncbi request reprint The prognostic importance of immunohistochemically detected node metastases in resected esophageal adenocarcinoma
    Tara A Waterman
    Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Ann Thorac Surg 78:1161-9; discussion 1161-9. 2004
    ..My colleagues and I hypothesized that the extent of nodal disease determined by both H&E and IHC examination would more accurately predict survival than either technique alone...
  42. ncbi request reprint Cardiac mucosa in the remnant esophagus after esophagectomy is an acquired epithelium with Barrett's-like features
    Reginald V N Lord
    Department of Surgery, University of Southern California Keck School of Medicine, Los Angeles, Calif, USA
    Surgery 136:633-40. 2004
    ..The aims of this study were, first, to investigate whether cardiac mucosa can be acquired in the remnant cervical esophagus after esophagectomy and cervical esophagogastrostomy and, second, to characterize this mucosa if present...
  43. ncbi request reprint Increased acid exposure in patients with gastroesophageal reflux disease influences cyclooxygenase-2 gene expression in the squamous epithelium of the lower esophagus
    Nahid Hamoui
    Department of Surgery, Division of Thoracic and Foregut Surgery, University of Southern California, Los Angeles 90033, USA
    Arch Surg 139:712-6; discussion 716-7. 2004
    ..PATIENTS, DESIGN, AND SETTING: Prospective analysis of 61 patients initially seen with reflux symptoms at a private academic hospital...
  44. ncbi request reprint En bloc vs transhiatal esophagectomy for stage T3 N1 adenocarcinoma of the distal esophagus
    Jan Johansson
    Department of Surgery, Lund University Hospital, Lund, Sweden
    Arch Surg 139:627-31; discussion 631-3. 2004
    ..En bloc esophagectomy (EBE) provides improved survival over transhiatal esophagectomy (THE) in patients with similarly sized transmural tumors (T3) and lymph node metastases (N1)...
  45. ncbi request reprint Endoscopic mucosal resection as a staging technique to determine the depth of invasion of esophageal adenocarcinoma
    Mary S Maish
    Department of Surgery, The University of Southern California, Keck School of Medicine, Los Angeles, California, USA
    Ann Thorac Surg 78:1777-82. 2004
    ....
  46. ncbi request reprint Indications and technique of colon and jejunal interpositions for esophageal disease
    Mary S Maish
    Department of Surgery, Keck School of Medicine, University of Southern California, 1510 San Pablo Street, Suite 514, Los Angeles, CA 90033, USA
    Surg Clin North Am 85:505-14. 2005
    ....
  47. ncbi request reprint Editorial comment: The short esophagus: going, going, gone?
    Steven R Demeester
    Surgery 133:364-7. 2003
  48. doi request reprint Plasma DNA is more reliable than carcinoembryonic antigen for diagnosis of recurrent esophageal cancer
    Farzaneh Banki
    Department of Surgery, University of California, Keck School of Medicine, Los Angeles, CA, USA
    J Am Coll Surg 207:30-5. 2008
    ..The sensitivity and specificity of these markers in the diagnosis of recurrent esophageal cancer have not been compared...
  49. ncbi request reprint Complications of achalasia surgery
    Andrew E Luckey
    The University of Southern California Keck School of Medicine, Los Angeles 90033, USA
    Thorac Surg Clin 16:95-8. 2006
    ..Further studies on the best location for the myotomy as well as the best type of fundoplication will help refine the procedure for future generations of patients...
  50. doi request reprint High intraepithelial eosinophil counts in esophageal squamous epithelium are not specific for eosinophilic esophagitis in adults
    Sonali Rodrigo
    Department of Surgical Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Am J Gastroenterol 103:435-42. 2008
    ..This is based on data that the number of intraepithelial eosinophils in gastroesophageal reflux disease (GERD) is less than 20/hpf. This study tests this belief...
  51. ncbi request reprint Molecular determinants in targeted therapy for esophageal adenocarcinoma
    Daniel Vallbohmer
    Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, USA
    Arch Surg 141:476-81; discussion 481-2. 2006
    ..Cyclooxygenase 2 (COX-2), vascular endothelial growth factor (VEGF), and epidermal growth factor receptor (EGFR) are useful biological determinants in targeted therapy for esophageal adenocarcinoma...
  52. ncbi request reprint Plasma DNA as a molecular marker for completeness of resection and recurrent disease in patients with esophageal cancer
    Farzaneh Banki
    Division of Thoracic Foregut Surgery, Department of Surgery, Keck School of Medicine, University of Southern California Los Angeles, 1950 San Pablo, Los Angeles, CA 90033, USA
    Arch Surg 142:533-8; discussion 538-9. 2007
    ..To identify a marker for completeness of resection and recurrent disease in patients with esophageal cancer...