MARK L DELL'ACQUA

Summary

Affiliation: University of Colorado Health Sciences Center
Country: USA

Publications

  1. ncbi AKAP79/150 anchoring of calcineurin controls neuronal L-type Ca2+ channel activity and nuclear signaling
    Seth F Oliveria
    Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA
    Neuron 55:261-75. 2007
  2. ncbi Regulation of neuronal PKA signaling through AKAP targeting dynamics
    MARK L DELL'ACQUA
    Department of Pharmacology, University of Colorado at Denver and Health Sciences Center at Fitzsimons, P O Box 6511, Mail Stop 8303, Aurora, CO 80045 0508, USA
    Eur J Cell Biol 85:627-33. 2006
  3. ncbi Regulation of postsynaptic structure and function by an A-kinase anchoring protein-membrane-associated guanylate kinase scaffolding complex
    Holly R Robertson
    Department of Pharmacology, School of Medicine, University of Colorado Denver, Aurora, Colorado 80045, USA
    J Neurosci 29:7929-43. 2009
  4. ncbi cAMP-dependent protein kinase postsynaptic localization regulated by NMDA receptor activation through translocation of an A-kinase anchoring protein scaffold protein
    Karen E Smith
    Department of Pharmacology, University of Colorado at Denver, Health Sciences Center, Aurora, Colorado 80045, USA
    J Neurosci 26:2391-402. 2006
  5. ncbi Palmitoylation of A-kinase anchoring protein 79/150 regulates dendritic endosomal targeting and synaptic plasticity mechanisms
    Dove J Keith
    Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado 80045, USA
    J Neurosci 32:7119-36. 2012
  6. ncbi Localized calcineurin confers Ca2+-dependent inactivation on neuronal L-type Ca2+ channels
    Seth F Oliveria
    Department of Pharmacology, University of Colorado School of Medicine, Aurora, Colorado 80045, USA
    J Neurosci 32:15328-37. 2012
  7. ncbi CaMKII "autonomy" is required for initiating but not for maintaining neuronal long-term information storage
    Isabelle Buard
    Department of Pharmacology, University of Colorado Denver School of Medicine, Aurora, Colorado 80045, USA
    J Neurosci 30:8214-20. 2010
  8. ncbi Regulation of A-kinase anchoring protein 79/150-cAMP-dependent protein kinase postsynaptic targeting by NMDA receptor activation of calcineurin and remodeling of dendritic actin
    Lisa L Gomez
    Department of Pharmacology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Neurosci 22:7027-44. 2002
  9. ncbi Association of an A-kinase-anchoring protein signaling scaffold with cadherin adhesion molecules in neurons and epithelial cells
    Jessica A Gorski
    Department of Pharmacology, University of Colorado at Denver and Health Sciences Center, Aurora, CO 80045, USA
    Mol Biol Cell 16:3574-90. 2005
  10. ncbi Phosphorylation regulates removal of synaptic N-methyl-D-aspartate receptors after withdrawal from chronic ethanol exposure
    Peter Clapp
    University of Colorado Denver, School of Medicine, MS 8303, P O Box 6511, 12800 E 19th Avenue, Aurora, CO 80045, USA
    J Pharmacol Exp Ther 332:720-9. 2010

Collaborators

  • Ronald K Freund
  • John D Scott
  • William A Sather
  • Steven J Coultrap
  • K Ulrich Bayer
  • Dong Ho Youn
  • Rujun Kang
  • Timothy A Benke
  • Seth F Oliveria
  • Emily S Gibson
  • Jennifer L Sanderson
  • Holly R Robertson
  • Simon A Hinke
  • Karen E Smith
  • Katherine E Brandao
  • Dove J Keith
  • Peter Clapp
  • Isabelle Buard
  • Lisa L Gomez
  • Eric A Horne
  • Jessica A Gorski
  • Vincenzo Cirulli
  • Allison Ulman
  • Philip J Dittmer
  • Manuel F Navedo
  • Patrick J Nygren
  • L Fernando Santana
  • S Rock Levinson
  • Anders Tengholm
  • Lorene K Langeberg
  • Antonio J Jimenez-Caliani
  • Alaa El-Husseini
  • Kevin M Woolfrey
  • Geng Tian
  • Jennifer L Whiting
  • Kyle Olszewski
  • Yong Seok Lee
  • Paula L Hoffman
  • Alcino J Silva
  • Eric Horne
  • Shuvo Alam

Detail Information

Publications15

  1. ncbi AKAP79/150 anchoring of calcineurin controls neuronal L-type Ca2+ channel activity and nuclear signaling
    Seth F Oliveria
    Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA
    Neuron 55:261-75. 2007
    ..Additionally, activation of the transcription factor NFATc4 via local Ca2+ influx through L-type channels requires AKAP79/150, suggesting that this signaling complex promotes neuronal L channel signaling to the nucleus through NFATc4...
  2. ncbi Regulation of neuronal PKA signaling through AKAP targeting dynamics
    MARK L DELL'ACQUA
    Department of Pharmacology, University of Colorado at Denver and Health Sciences Center at Fitzsimons, P O Box 6511, Mail Stop 8303, Aurora, CO 80045 0508, USA
    Eur J Cell Biol 85:627-33. 2006
    ....
  3. ncbi Regulation of postsynaptic structure and function by an A-kinase anchoring protein-membrane-associated guanylate kinase scaffolding complex
    Holly R Robertson
    Department of Pharmacology, School of Medicine, University of Colorado Denver, Aurora, Colorado 80045, USA
    J Neurosci 29:7929-43. 2009
    ..Overall, these results demonstrate a novel structural role for AKAP79/150 in which the N-terminal targeting domain induces dendritic filopodia and binding to MAGUKs promotes spine enlargement and AMPAR recruitment...
  4. ncbi cAMP-dependent protein kinase postsynaptic localization regulated by NMDA receptor activation through translocation of an A-kinase anchoring protein scaffold protein
    Karen E Smith
    Department of Pharmacology, University of Colorado at Denver, Health Sciences Center, Aurora, Colorado 80045, USA
    J Neurosci 26:2391-402. 2006
    ..In addition, our observations demonstrate that AKAPs serve not solely as stationary anchors in cells but also as dynamic signaling components...
  5. ncbi Palmitoylation of A-kinase anchoring protein 79/150 regulates dendritic endosomal targeting and synaptic plasticity mechanisms
    Dove J Keith
    Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado 80045, USA
    J Neurosci 32:7119-36. 2012
    ..These findings emphasize the emerging importance of palmitoylation in controlling synaptic function and reveal novel roles for the AKAP79/150 signaling complex in dendritic endosomes...
  6. ncbi Localized calcineurin confers Ca2+-dependent inactivation on neuronal L-type Ca2+ channels
    Seth F Oliveria
    Department of Pharmacology, University of Colorado School of Medicine, Aurora, Colorado 80045, USA
    J Neurosci 32:15328-37. 2012
    ..Hence, our investigation of AKAP79/150-anchored CaN reconciles the CaM-based model of CDI with an earlier, seemingly contradictory model based on dephosphorylation signaling...
  7. ncbi CaMKII "autonomy" is required for initiating but not for maintaining neuronal long-term information storage
    Isabelle Buard
    Department of Pharmacology, University of Colorado Denver School of Medicine, Aurora, Colorado 80045, USA
    J Neurosci 30:8214-20. 2010
    ..Thus, CaMKII autonomy provides a short-term molecular memory that is important in the signal computation leading to memory formation, but is not required as long-term memory store...
  8. ncbi Regulation of A-kinase anchoring protein 79/150-cAMP-dependent protein kinase postsynaptic targeting by NMDA receptor activation of calcineurin and remodeling of dendritic actin
    Lisa L Gomez
    Department of Pharmacology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Neurosci 22:7027-44. 2002
    ....
  9. ncbi Association of an A-kinase-anchoring protein signaling scaffold with cadherin adhesion molecules in neurons and epithelial cells
    Jessica A Gorski
    Department of Pharmacology, University of Colorado at Denver and Health Sciences Center, Aurora, CO 80045, USA
    Mol Biol Cell 16:3574-90. 2005
    ..This neuronal regulation of AKAP79/150 targeting to cadherins may be important in functional and structural synaptic modifications underlying plasticity...
  10. ncbi Phosphorylation regulates removal of synaptic N-methyl-D-aspartate receptors after withdrawal from chronic ethanol exposure
    Peter Clapp
    University of Colorado Denver, School of Medicine, MS 8303, P O Box 6511, 12800 E 19th Avenue, Aurora, CO 80045, USA
    J Pharmacol Exp Ther 332:720-9. 2010
    ....
  11. ncbi Phospholipase C is required for changes in postsynaptic structure and function associated with NMDA receptor-dependent long-term depression
    Eric A Horne
    Department of Pharmacology, School of Medicine, University of Colorado at Denver and Health Sciences Center, Aurora, Colorado 80045, USA
    J Neurosci 27:3523-34. 2007
    ..Thus, PLC signaling is required for structural and functional changes in spine actin, PSD scaffolding, and AMPAR trafficking underlying postsynaptic expression of LTD...
  12. ncbi A-kinase anchoring protein 150 expression in a specific subset of TRPV1- and CaV 1.2-positive nociceptive rat dorsal root ganglion neurons
    Katherine E Brandao
    Program in Neuroscience, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045, USA
    J Comp Neurol 520:81-99. 2012
    ..Thus AKAP150 is expressed in small, nociceptive DRG neurons, where it is targeted to membrane regions and where it may play a role in the modulation of ion channel phosphorylation states required for hyperalgesia...
  13. ncbi CaMKII autonomy is substrate-dependent and further stimulated by Ca2+/calmodulin
    Steven J Coultrap
    Department of Pharmacology, University of Colorado Denver School of Medicine, Aurora, Colorado 80045, USA
    J Biol Chem 285:17930-7. 2010
    ..Such regulation still allows molecular memory of previous Ca(2+) signals, but prevents complete uncoupling from subsequent cellular stimulation...
  14. ncbi AKAP signaling complexes in regulation of excitatory synaptic plasticity
    Jennifer L Sanderson
    Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045, USA
    Neuroscientist 17:321-36. 2011
    ....
  15. ncbi Anchored phosphatases modulate glucose homeostasis
    Simon A Hinke
    Department of Pharmacology, Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA
    EMBO J 31:3991-4004. 2012
    ..Thus anchored signalling events that facilitate insulin secretion and glucose homeostasis may be set by AKAP150 associated phosphatase activity...