David Della-Morte

Summary

Affiliation: University of Miami
Country: USA

Publications

  1. doi request reprint Waist circumference but not body mass index predicts long-term mortality in elderly subjects with chronic heart failure
    Gianluca Testa
    Department of Clinical Medicine, Cardiovascular Science and Immunology, Cattedra di Geriatria, Universita degli Studi di Napoli Federico II, Naples, Italy
    J Am Geriatr Soc 58:1433-40. 2010
  2. doi request reprint Measurement of subclinical carotid atherosclerosis may help in predicting risk for stroke in patients with diabetes
    David Della-Morte
    Department of Neurology, Miller School of Medicine, University of Miami, Clinical Research Building, Miami, FL 33136, USA
    Metab Brain Dis 28:337-9. 2013
  3. doi request reprint Genetics and genomics of ischemic tolerance: focus on cardiac and cerebral ischemic preconditioning
    David Della-Morte
    Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    Pharmacogenomics 13:1741-57. 2012
  4. doi request reprint Genetics of ischemic stroke, stroke-related risk factors, stroke precursors and treatments
    David Della-Morte
    Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    Pharmacogenomics 13:595-613. 2012
  5. doi request reprint Dizziness and vertigo
    David Della-Morte
    Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL 33101, USA
    Front Neurol Neurosci 30:22-5. 2012
  6. pmc Genetic linkage of serum homocysteine in Dominican families: the Family Study of Stroke Risk and Carotid Atherosclerosis
    David Della-Morte
    Department of Neurology, Miller School of Medicine, University of Miami, Clinical Research Building, Miami, Fla 33136, USA
    Stroke 41:1356-62. 2010
  7. pmc Intrapetrous internal carotid artery dissection and essential thrombocythemia: what relationship? A case report
    Daniele D'Ambrosio
    Department of Internal Medicine, Cardiovascular Sciences, and Immunology, University Federico II, Naples, Italy
    Cases J 1:354. 2008
  8. pmc Association between variations in coagulation system genes and carotid plaque
    David Della-Morte
    Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL, USA
    J Neurol Sci 323:93-8. 2012
  9. doi request reprint Clinical frailty and long-term mortality in elderly subjects with diabetes
    Francesco Cacciatore
    Dipartimento di Medicina Clinica e Scienze Cardiovascolari ed Immunologiche, Cattedra di Geriatria, Universita degli Studi di Napoli Federico II, 80131, Naples, Italy
    Acta Diabetol 50:251-60. 2013
  10. doi request reprint Depressive symptoms predict mortality in elderly subjects with chronic heart failure
    Gianluca Testa
    Dipartimento di Medicina Clinica, Scienze Cardiovascolari ed Immunologiche, Cattedra di Geriatria, Universita degli Studi di Napoli Federico II, Naples, Italy
    Eur J Clin Invest 41:1310-7. 2011

Collaborators

Detail Information

Publications44

  1. doi request reprint Waist circumference but not body mass index predicts long-term mortality in elderly subjects with chronic heart failure
    Gianluca Testa
    Department of Clinical Medicine, Cardiovascular Science and Immunology, Cattedra di Geriatria, Universita degli Studi di Napoli Federico II, Naples, Italy
    J Am Geriatr Soc 58:1433-40. 2010
    ..To examine whether waist circumference (WC) and body-mass index (BMI) can predict long-term mortality in elderly subjects with and without chronic heart failure (CHF)...
  2. doi request reprint Measurement of subclinical carotid atherosclerosis may help in predicting risk for stroke in patients with diabetes
    David Della-Morte
    Department of Neurology, Miller School of Medicine, University of Miami, Clinical Research Building, Miami, FL 33136, USA
    Metab Brain Dis 28:337-9. 2013
    ..In this editorial we discuss the opportunity to prevent the onset of vascular disease in their "preclinical or subclinical" stage in patients with higher risk for stroke such as diabetic patients. ..
  3. doi request reprint Genetics and genomics of ischemic tolerance: focus on cardiac and cerebral ischemic preconditioning
    David Della-Morte
    Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    Pharmacogenomics 13:1741-57. 2012
    ....
  4. doi request reprint Genetics of ischemic stroke, stroke-related risk factors, stroke precursors and treatments
    David Della-Morte
    Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    Pharmacogenomics 13:595-613. 2012
    ....
  5. doi request reprint Dizziness and vertigo
    David Della-Morte
    Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL 33101, USA
    Front Neurol Neurosci 30:22-5. 2012
    ..Careful medical history, physical examination, neuroimaging and ear, nose, and throat studies may help to distinguish vascular vertigo from other causes...
  6. pmc Genetic linkage of serum homocysteine in Dominican families: the Family Study of Stroke Risk and Carotid Atherosclerosis
    David Della-Morte
    Department of Neurology, Miller School of Medicine, University of Miami, Clinical Research Building, Miami, Fla 33136, USA
    Stroke 41:1356-62. 2010
    ..However, the exact mechanism of documented and novel total homocysteine quantitative trait loci to that risk is unknown...
  7. pmc Intrapetrous internal carotid artery dissection and essential thrombocythemia: what relationship? A case report
    Daniele D'Ambrosio
    Department of Internal Medicine, Cardiovascular Sciences, and Immunology, University Federico II, Naples, Italy
    Cases J 1:354. 2008
    ..The diagnosis of essential thrombocythemia was performed by bone marrow biopsy. The essential thrombocythemia may cause endothelial dysfunction and predispose to vascular damage such as carotid artery dissection...
  8. pmc Association between variations in coagulation system genes and carotid plaque
    David Della-Morte
    Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL, USA
    J Neurol Sci 323:93-8. 2012
    ..The objective of this study is to examine the association between single nucleotide polymorphisms (SNPs) in coagulation system genes and subclinical carotid plaque phenotypes...
  9. doi request reprint Clinical frailty and long-term mortality in elderly subjects with diabetes
    Francesco Cacciatore
    Dipartimento di Medicina Clinica e Scienze Cardiovascolari ed Immunologiche, Cattedra di Geriatria, Universita degli Studi di Napoli Federico II, 80131, Naples, Italy
    Acta Diabetol 50:251-60. 2013
    ..This phenomenon is particularly evident in men. Thus, clinical frailty may be considered a new prognostic factor to identify subjects with diabetes at high risk of mortality...
  10. doi request reprint Depressive symptoms predict mortality in elderly subjects with chronic heart failure
    Gianluca Testa
    Dipartimento di Medicina Clinica, Scienze Cardiovascolari ed Immunologiche, Cattedra di Geriatria, Universita degli Studi di Napoli Federico II, Naples, Italy
    Eur J Clin Invest 41:1310-7. 2011
    ..Moreover, depression status is also related to poor prognosis in advancing age. Thus, we sought to determine whether depressive status predicts long-term mortality in subject with or without CHF...
  11. pmc Ethnic differences in carotid artery diameter and stiffness: the Northern Manhattan Study
    Matthew S Markert
    Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL 33101, USA
    Atherosclerosis 219:827-32. 2011
    ..Our objective was to investigate differences in carotid artery diameter and stiffness between race/ethnic groups, and examine whether these race/ethnic differences were age-dependent...
  12. pmc Traditional cardiovascular risk factors explain the minority of the variability in carotid plaque
    Frank Kuo
    Department of Neurology, Miller School of Medicine, University of Miami, Clinical Research Building, CRB 1348, 1120 NW 14th Street, Miami, FL 33136, USA
    Stroke 43:1755-60. 2012
    ..Identifying factors underlying the variability in burden of atherosclerotic carotid plaque unexplained by traditional vascular risk factors may help target novel preventive strategies...
  13. pmc Age-related reduction of cerebral ischemic preconditioning: myth or reality?
    David Della-Morte
    Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL, USA Department of Advanced Biotechnologies and Bioimaging, IRCCS San Raffaele, Rome, Italy
    Clin Interv Aging 8:1055-61. 2013
    ..In this article, animal and human cerebral ischemic preconditioning, its age-related difference, and its potential therapeutical applications are discussed. ..
  14. doi request reprint Butyryl-cholinesterase is related to muscle mass and strength. A new biomarker to identify elderly subjects at risk of sarcopenia
    Francesco Cacciatore
    Department of Translational Medical Sciences, University of Naples Federico II, Naples, Italy
    Biomark Med 9:669-78. 2015
    ..To determine the relationship between Butyryl-cholinesterase (α-glycoprotein synthesized in the liver, b-CHE) and muscle mass and strength...
  15. pmc Genetic variants in LEKR1 and GALNT10 modulate sex-difference in carotid intima-media thickness: a genome-wide interaction study
    Chuanhui Dong
    Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    Atherosclerosis 240:462-7. 2015
    ..There is an established sex-difference in carotid artery intima-media thickness (cIMT), a recognized marker of subclinical atherosclerosis. However, the genetic underpinnings of sex-differences in gene-IMT associations are largely unknown...
  16. pmc Biomarkers for ischemic preconditioning: finding the responders
    Sebastian Koch
    Miller School of Medicine, Department of Neurology, University of Miami, Miami, Florida, USA
    J Cereb Blood Flow Metab 34:933-41. 2014
    ..Given the manifold biologic effects of preconditioning a panel of multiple serum biomarkers or genomic assessments of upstream regulators may most accurately reflect the full spectrum of a preconditioning response. ..
  17. doi request reprint Charlson Comorbidity Index does not predict long-term mortality in elderly subjects with chronic heart failure
    Gianluca Testa
    Dipartimento di Medicina Clinica, Scienze Cardiovascolari ed Immunologiche, Cattedra di Geriatria, Universita degli Studi di Napoli Federico II, Naples, Italy
    Age Ageing 38:734-40. 2009
    ..No studies are available on the ability of CCI to predict mortality in CHF elderly subjects. The aim of the present study was to assess if CCI was able to predict long-term mortality in a random sample of elderly CHF subjects...
  18. doi request reprint Atenolol use is associated with long-term mortality in community-dwelling older adults with hypertension
    Gianluca Testa
    Translational Medical Sciences, University of Naples Federico II, Naples, Italy Health Sciences Faculty, University of Molise, Campobasso, Italy
    Geriatr Gerontol Int 14:153-8. 2014
    ..The aim of the present study was to evaluate long-term mortality in community-dwelling hypertensive older adults taking atenolol...
  19. pmc Association of the sirtuin and mitochondrial uncoupling protein genes with carotid plaque
    Chuanhui Dong
    Department of Neurology, Miller School of Medicine, University of Miami, Miami, Florida, United States of America
    PLoS ONE 6:e27157. 2011
    ..This study sought to investigate the association between genetic variants in the SIRT and UCP genes and carotid plaque...
  20. doi request reprint Sirtuin/uncoupling protein gene variants and carotid plaque area and morphology
    Chuanhui Dong
    Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL, USA
    Int J Stroke 10:1247-52. 2015
    ..Sirtuins and uncoupling proteins have been implicated in cardiovascular diseases by controlling oxidative stress...
  21. pmc Novel genetic variants modify the effect of smoking on carotid plaque burden in Hispanics
    David Della-Morte
    Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL, United States Department of Systems Medicine, School of Medicine, University of Tor Vergata Rome, Italy IRCCS San Raffaele Pisana, Rome, Italy
    J Neurol Sci 344:27-31. 2014
    ..A genome-wide scan was performed for smoking×single nucleotide polymorphism (SNP) interactions on carotid plaque burden (CPB) to identify the potential genetic moderators in Hispanics...
  22. pmc A follow-up study for left ventricular mass on chromosome 12p11 identifies potential candidate genes
    David Della-Morte
    Department of Neurology, Evelyn F McKnight Brain Institute, Miller School of Medicine, University of Miami, Miami, FL, USA
    BMC Med Genet 12:100. 2011
    ..In the present study, we use association analysis to further study the genetic effect on LVM...
  23. doi request reprint Treatment for chronic heart failure in the elderly: current practice and problems
    Pasquale Abete
    Dipartimento di Medicina Clinica, Scienze Cardiovascolari ed Immunologiche, Cattedra di Geriatria, Universita degli Studi di Napoli Federico II, 80131 Naples, Italy
    Heart Fail Rev 18:529-51. 2013
    ..Follow-up of CHF elderly patient is very important but tele-medicine is the future. Finally, self-care management, caregiver training, and multidimensional team represent the critical point of the treatment for CHF elderly patients...
  24. pmc Ischemic preconditioning in the younger and aged heart
    Pasquale Abete
    Dipartimento di Medicina Clinica, Scienze Cardiovascolari ed Immunologiche, Cattedra di Geriatria, Universita degli Studi di Napoli Federico II, Naples, Italy
    Aging Dis 2:138-48. 2011
    ..Thus, both physical activity and caloric restriction are confirmed as powerful anti-aging interventions capable to restore age-dependent reduction of a critical endogenous protective mechanism such as ischemic preconditioning...
  25. pmc Clinical application of ischemic preconditioning in the elderly
    Pasquale Abete
    Dipartimento di Medicina Clinica, Scienze Cardiovascolari ed Immunologiche, Cattedra di Geriatria, Universita degli Studi di Napoli Federico II, Naples, Italy
    Dose Response 8:34-40. 2009
    ....
  26. pmc Cigarette Smoking and Carotid Plaque Echodensity in the Northern Manhattan Study
    Dixon Yang
    Department of Neurology, Miller School of Medicine, University of Miami, Miami, Fla, USA
    Cerebrovasc Dis 40:136-43. 2015
    ..We sought to determine the association between cigarette smoking and carotid plaque ultrasound morphology in a multiethnic cohort...
  27. pmc The relationship between carotid intima-media thickness and carotid plaque in the Northern Manhattan Study
    Tatjana Rundek
    Department of Neurology, University of Miami, Miller School of Medicine, Miami, FL, USA Department of Public Health Sciences, University of Miami, Miller School of Medicine, Miami, FL, USA Electronic address
    Atherosclerosis 241:364-70. 2015
    ..Whether cIMT and CP are distinct phenotypes or single traits at different stages of atherosclerotic development is unclear. We explored the relationship between these markers in the population-based Northern Manhattan Study...
  28. pmc Evidence to Maintain the Systolic Blood Pressure Treatment Threshold at 140 mm Hg for Stroke Prevention: The Northern Manhattan Study
    Chuanhui Dong
    From the Department of Neurology C D, D D M, T R, C B W, R L S, Department of Public Health Sciences T R, C B W, R L S, and John T McDonald Department of Human Genetics R L S, Miller School of Medicine, University of Miami, FL Departments of Neurology and Epidemiology, Columbia University, New York, NY M S V E, Department of Systems Medicine, School of Medicine, University of Rome, Rome, Italy D D M and BioBIM Multidisciplinary Interinstitutional BioBank, IRCCS San Raffaele Pisana, Rome, Italy D D M
    Hypertension 67:520-6. 2016
    ....
  29. doi request reprint Phase angle as bioelectrical marker to identify elderly patients at risk of sarcopenia
    Claudia Basile
    Department of Translational Medical Sciences, University of Naples Federico II, Naples, Italy
    Exp Gerontol 58:43-6. 2014
    ..245, p=0.031; muscular mass β=0.623, p<0.01). Thus, PhA is inversely related to muscle mass and strength in elderly subjects and it may be considered a good bioelectrical marker to identify elderly patients at risk of sarcopenia. ..
  30. doi request reprint Ischemic preconditioning in the aging heart: from bench to bedside
    Pasquale Abete
    Dipartimento di Medicina Clinica, Scienze Cardiovascolari ed Immunologiche, Cattedra di Geriatria, Universita degli Studi di Napoli Federico II, Naples, Italy
    Ageing Res Rev 9:153-62. 2010
    ....
  31. pmc High-density lipoprotein subfractions and carotid plaque: the Northern Manhattan Study
    Eduard Tiozzo
    Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, FL, USA Electronic address
    Atherosclerosis 237:163-8. 2014
    ..The objective of this cross-sectional analysis was to investigate the relation between two major high-density lipoprotein cholesterol (HDL-C) subfractions (HDL2-C and HDL3-C) and carotid plaque in a population based cohort...
  32. pmc Neuroprotective properties of marrow-isolated adult multilineage-inducible cells in rat hippocampus following global cerebral ischemia are enhanced when complexed to biomimetic microcarriers
    Elisa Garbayo
    Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida, USA
    J Neurochem 119:972-88. 2011
    ....
  33. pmc Short-term effect of atorvastatin on carotid artery elasticity: a pilot study
    Elizabeth V Ratchford
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Stroke 42:3460-4. 2011
    ..This study examined the short-term effects of atorvastatin 80 mg daily on carotid elasticity measured by high-resolution B-mode ultrasound...
  34. doi request reprint Serum withdrawal after embryoid body formation does not impair cardiomyocyte development from mouse embryonic stem cells
    Gianluca Testa
    CEINGE Biotecnologie Avanzate, Naples, Italy
    Cytotherapy 13:350-6. 2011
    ..We report on an embryoid body (EB)-based procedure for cardiomyocyte differentiation of mESCs in which serum is provided only in the earliest step (hanging drop, 0-2 days)...
  35. pmc Transient ischemic attack before nonlacunar ischemic stroke in the elderly
    David Della Morte
    Department of Internal Medicine, Cardiovascular Sciences, and Immunology, University Federico II, Naples, Italy
    J Stroke Cerebrovasc Dis 17:257-62. 2008
    ..The purpose of this study was to determine the neuroprotective effect of TIAs (clinical equivalent of cerebral ischemic preconditioning) to neurologic damage after cerebral ischemic injury in patients over 65 years of age...
  36. pmc Lipids and carotid plaque in the Northern Manhattan Study (NOMAS)
    Hannah Gardener
    Department of Neurology, Miller School of Medicine, University of Miami, FL, USA
    BMC Cardiovasc Disord 9:55. 2009
    ..The objective of this cross-sectional analysis was to investigate the relation between blood lipids and carotid plaque...
  37. ncbi request reprint Ensuring Sample Quality for Biomarker Discovery Studies - Use of ICT Tools to Trace Biosample Life-cycle
    Silvia Riondino
    BioBIM Multidisciplinary Interinstitutional BioBank, IRCCS San Raffaele Pisana Research Center, Rome, Italy Medical Oncology, Policlinico Tor Vergata Biospecimen Cancer Biorepository IIV Bio Ca Re, Department of Internal Medicine, University of Rome Tor Vergata, Tor Vergata Clinical Center, Rome, Italy
    Cancer Genomics Proteomics 12:291-9. 2015
    ..All the above will ensure proper sample exchangeability among research facilities and will represent the starting point of all future personalized medicine-based clinical trials. ..
  38. pmc Ventricular fibrillation-induced cardiac arrest in the rat as a model of global cerebral ischemia
    Kunjan R Dave
    The Cerebral Vascular Disease Research Laboratories, Department of Neurology, University of Miami, Miami, FL 33136
    Transl Stroke Res 4:571-8. 2013
    ..We propose that this method of VF-induced CA in rat provides a tool to study the mechanism of CA-induced neuronal death without compromising heart functions. ..
  39. pmc The short-term effect of atorvastatin on carotid plaque morphology assessed by computer-assisted gray-scale densitometry: a pilot study
    David Della-Morte
    Department of Neurology, Leonard M Miller School of Medicine, University of Miami, Miami, FL, USA
    Neurol Res 33:991-4. 2011
    ..71 (95% confidence interval: 1.1-7.6, P<0.01). In conclusion, we observed decreased echolucency (increased echodensity) of carotid artery plaques after short-term treatment with atorvastatin...
  40. pmc Metabolic syndrome increases carotid artery stiffness: the Northern Manhattan Study
    David Della-Morte
    Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL 33101, USA
    Int J Stroke 5:138-44. 2010
    ..The metabolic syndrome and its components are established cardiovascular disease risk factors and may also increase arterial stiffness; however, data regarding this are limited...
  41. ncbi request reprint Resveratrol and ischemic preconditioning in the brain
    Ami P Raval
    Department of Neurology, Leonard M Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    Curr Med Chem 15:1545-51. 2008
    ..In this review, we will examine common signaling pathways, cellular targets of resveratrol, and ischemic preconditioning-induced neuroprotection as it relates to the brain...
  42. doi request reprint Genetic susceptibility to cerebrovascular disease
    David Della-Morte
    aDepartment of Neurology, Miller School of Medicine, University of Miami, Miami, Florida, USA bDepartment of Systems Medicine, School of Medicine, University of Rome Tor Vergata cIRCCS San Raffaele Pisana, Rome, Italy
    Curr Opin Lipidol 27:187-95. 2016
    ..In the present article, we discussed genetic susceptibility to CeVD, with particular emphasis on genetic studies of the associations between lipid traits and CeVD...
  43. pmc GABA synapses mediate neuroprotection after ischemic and epsilonPKC preconditioning in rat hippocampal slice cultures
    R Anthony DeFazio
    Cerebral Vascular Disease Research Center, Department of Neurology, Leonard M Miller School of Medicine, University of Miami, Miami, Florida 33101, USA
    J Cereb Blood Flow Metab 29:375-84. 2009
    ..We conclude that neuroprotection conferred by preconditioning depends on functional modifications of GABA synapses...
  44. doi request reprint Joint effect of physical activity and body mass index on mortality for acute myocardial infarction in the elderly: role of preinfarction angina as equivalent of ischemic preconditioning
    Pasquale Abete
    Dipartimento di Medicina Clinica, Scienze Cardiovascolari ed Immunologiche, Cattedra di Geriatria, University of Naples Federico II, Naples, Italy
    Eur J Cardiovasc Prev Rehabil 16:73-9. 2009
    ..This study aims to examine the interaction between physical activity and body mass index (BMI) in preserving the cardioprotective effect of PrA in elderly patients with AMI...