Melissa P DelBello

Summary

Affiliation: University of Cincinnati
Country: USA

Publications

  1. ncbi request reprint A 12-week single-blind trial of quetiapine for the treatment of mood symptoms in adolescents at high risk for developing bipolar I disorder
    Melissa P DelBello
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    J Clin Psychiatry 68:789-95. 2007
  2. pmc Characterizing impulsivity in mania
    Stephen M Strakowski
    Division of Bipolar Disorders Research, Universtiy of Cincinnati College of Medicine, Cincinnati, OH, USA
    Bipolar Disord 11:41-51. 2009
  3. pmc Neuroanatomical characterization of child offspring of bipolar parents
    Manpreet K Singh
    Department of Psychiatry, Division of Bipolar Disorders Research, University of Cincinnati, OH 45267 0559, USA
    J Am Acad Child Adolesc Psychiatry 47:526-31. 2008
  4. doi request reprint The functional neuroanatomy of bipolar disorder
    Michael A Cerullo
    Department of Psychiatry, Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Int Rev Psychiatry 21:314-22. 2009
  5. doi request reprint Neurocircuitry of generalized anxiety disorder in adolescents: a pilot functional neuroimaging and functional connectivity study
    Jeffrey R Strawn
    Department of Psychiatry and Behavioral Neuroscience College of Medicine, University of Cincinnati, Cincinnati, Ohio 45267 0559, USA
    Depress Anxiety 29:939-47. 2012
  6. pmc A longitudinal functional connectivity analysis of the amygdala in bipolar I disorder across mood states
    Michael A Cerullo
    Division of Bipolar Disorders Research, Department of Psychiatry Center for Imaging Research, University of Cincinnati College of Medicine, Cincinnati, OH 45219 0516, USA
    Bipolar Disord 14:175-84. 2012
  7. ncbi request reprint Neurochemical effects of olanzapine in first-hospitalization manic adolescents: a proton magnetic resonance spectroscopy study
    Melissa P DelBello
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Neuropsychopharmacology 31:1264-73. 2006
  8. ncbi request reprint Effects of co-occurring cannabis use disorders on the course of bipolar disorder after a first hospitalization for mania
    Stephen M Strakowski
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, 2341 Albert Sabin Way, Cincinnati, OH 45267, USA
    Arch Gen Psychiatry 64:57-64. 2007
  9. pmc Preliminary evidence for increased frontosubcortical activation on a motor impulsivity task in mixed episode bipolar disorder
    David E Fleck
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0583, USA
    J Affect Disord 133:333-9. 2011
  10. ncbi request reprint Twelve-month outcome of adolescents with bipolar disorder following first hospitalization for a manic or mixed episode
    Melissa P DelBello
    Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Am J Psychiatry 164:582-90. 2007

Detail Information

Publications106 found, 100 shown here

  1. ncbi request reprint A 12-week single-blind trial of quetiapine for the treatment of mood symptoms in adolescents at high risk for developing bipolar I disorder
    Melissa P DelBello
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    J Clin Psychiatry 68:789-95. 2007
    ..To investigate the effectiveness and tolerability of quetiapine for the treatment of adolescents at high risk for developing bipolar I disorder...
  2. pmc Characterizing impulsivity in mania
    Stephen M Strakowski
    Division of Bipolar Disorders Research, Universtiy of Cincinnati College of Medicine, Cincinnati, OH, USA
    Bipolar Disord 11:41-51. 2009
    ....
  3. pmc Neuroanatomical characterization of child offspring of bipolar parents
    Manpreet K Singh
    Department of Psychiatry, Division of Bipolar Disorders Research, University of Cincinnati, OH 45267 0559, USA
    J Am Acad Child Adolesc Psychiatry 47:526-31. 2008
    ..We hypothesized that at-risk (AR) children would exhibit abnormalities in brain regions that are involved in mood regulation...
  4. doi request reprint The functional neuroanatomy of bipolar disorder
    Michael A Cerullo
    Department of Psychiatry, Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Int Rev Psychiatry 21:314-22. 2009
    ..Additionally, most studies were confounded by patients taking psychotropic medications. Nonetheless, from this work an anterior limbic over-activation model of bipolar disorder is emerging...
  5. doi request reprint Neurocircuitry of generalized anxiety disorder in adolescents: a pilot functional neuroimaging and functional connectivity study
    Jeffrey R Strawn
    Department of Psychiatry and Behavioral Neuroscience College of Medicine, University of Cincinnati, Cincinnati, Ohio 45267 0559, USA
    Depress Anxiety 29:939-47. 2012
    ..We used standard fMRI and functional connectivity analyses to examine the functional neurocircuitry of GAD in adolescents...
  6. pmc A longitudinal functional connectivity analysis of the amygdala in bipolar I disorder across mood states
    Michael A Cerullo
    Division of Bipolar Disorders Research, Department of Psychiatry Center for Imaging Research, University of Cincinnati College of Medicine, Cincinnati, OH 45219 0516, USA
    Bipolar Disord 14:175-84. 2012
    ..To further understand the role of the amygdala in the generation of mood symptoms, we used functional magnetic resonance imaging (fMRI) to examine a group of patients with bipolar I disorder longitudinally...
  7. ncbi request reprint Neurochemical effects of olanzapine in first-hospitalization manic adolescents: a proton magnetic resonance spectroscopy study
    Melissa P DelBello
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Neuropsychopharmacology 31:1264-73. 2006
    ..Additionally, olanzapine-induced increases in choline may lead to alteration of abnormalities in cell membrane metabolism or second messenger pathways that are thought to be involved in the pathophysiology of bipolar disorder...
  8. ncbi request reprint Effects of co-occurring cannabis use disorders on the course of bipolar disorder after a first hospitalization for mania
    Stephen M Strakowski
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, 2341 Albert Sabin Way, Cincinnati, OH 45267, USA
    Arch Gen Psychiatry 64:57-64. 2007
    ..Cannabis use disorders commonly co-occur in bipolar disorder; however, the effects of cannabis abuse on outcome have been minimally studied...
  9. pmc Preliminary evidence for increased frontosubcortical activation on a motor impulsivity task in mixed episode bipolar disorder
    David E Fleck
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0583, USA
    J Affect Disord 133:333-9. 2011
    ..The aim of this study was to examine whether the neural correlates of motor impulsivity are distinct in patients with mixed mania...
  10. ncbi request reprint Twelve-month outcome of adolescents with bipolar disorder following first hospitalization for a manic or mixed episode
    Melissa P DelBello
    Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Am J Psychiatry 164:582-90. 2007
    ..The aim of this study was to examine the 12-month outcome of bipolar adolescents following an initial hospitalization for a manic or mixed episode...
  11. ncbi request reprint Effects of co-occurring alcohol abuse on the course of bipolar disorder following a first hospitalization for mania
    Stephen M Strakowski
    Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, 231 Albert Sabin Way ML0559, PO Box 670559, Cincinnati, OH 45267 0559, USA
    Arch Gen Psychiatry 62:851-8. 2005
    ..Alcohol-use disorders are common co-occurring conditions affecting bipolar patients, and this co-occurrence is negatively associated with outcome...
  12. ncbi request reprint Psychopathology in children of bipolar parents
    Manpreet K Singh
    Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    J Affect Disord 102:131-6. 2007
    ..Few studies have examined the psychopathological profiles of child offspring of bipolar parents. Such investigations are useful as a first step to identifying potential prodromal manifestations of bipolar disorder...
  13. pmc Functional magnetic resonance imaging brain activation in bipolar mania: evidence for disruption of the ventrolateral prefrontal-amygdala emotional pathway
    Stephen M Strakowski
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559 USA
    Biol Psychiatry 69:381-8. 2011
    ..We used functional magnetic resonance imaging (fMRI) to study manic bipolar subjects as they performed a cognitive task designed to examine the ventrolateral prefrontal emotional arousal network...
  14. doi request reprint Glutamatergic effects of divalproex in adolescents with mania: a proton magnetic resonance spectroscopy study
    Jeffrey R Strawn
    University of Cincinnati, College of Medicine, Cincinnati, OH 45267, USA
    J Am Acad Child Adolesc Psychiatry 51:642-51. 2012
    ....
  15. ncbi request reprint A double-blind randomized pilot study comparing quetiapine and divalproex for adolescent mania
    Melissa P DelBello
    Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    J Am Acad Child Adolesc Psychiatry 45:305-13. 2006
    ..To determine the comparative efficacy of quetiapine and divalproex for the treatment of adolescent mania...
  16. ncbi request reprint Adjunctive topiramate in hospitalized children and adolescents with bipolar disorders
    Drew H Barzman
    Cincinnati Children s Hospital Medical Center, Division of Child and Adolescent Psychiatry, and Department of Psychiatry, University of Cincinnati College of Medicine, Ohio 45267, USA
    J Child Adolesc Psychopharmacol 15:931-7. 2005
    ..The aim of this study was to assess topiramate as adjunctive treatment in children and adolescents hospitalized with bipolar disorders...
  17. ncbi request reprint Brain network dysfunction in bipolar disorder
    Caleb M Adler
    Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    CNS Spectr 11:312-20; quiz 323-4. 2006
    ..As neuroimaging techniques continue to improve, the underlying neural basis of bipolar disorder will be clarified...
  18. pmc Lithium treatment effects on Myo-inositol in adolescents with bipolar depression
    Nick C Patel
    Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0004, USA
    Biol Psychiatry 60:998-1004. 2006
    ..This study used proton magnetic resonance spectroscopy (1H MRS) to identify the in vivo effects of lithium on myo-inositol (mI) concentrations in adolescent bipolar depression...
  19. ncbi request reprint The efficacy and tolerability of quetiapine versus divalproex for the treatment of impulsivity and reactive aggression in adolescents with co-occurring bipolar disorder and disruptive behavior disorder(s)
    Drew H Barzman
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati, Cincinnati, Ohio, USA
    J Child Adolesc Psychopharmacol 16:665-70. 2006
    ..The aim of this study was to compare the efficacy and tolerability of quetiapine and divalproex for the treatment of impulsivity and reactive aggression in adolescents with co-occurring bipolar disorder and disruptive behavior disorders...
  20. ncbi request reprint Preliminary study of relationships among measures of depressive symptoms in adolescents with bipolar disorder
    Nick C Patel
    College of Pharmacy, Department of Psychiatry, University of Cincinnati College of Medicine, 3225 Eden Avenue, Cincinnati, OH 45267, USA
    J Child Adolesc Psychopharmacol 16:327-35. 2006
    ..We hypothesized that CDRS-R and HAM-D scores would be significantly correlated and both scales would be sensitive to change resulting from treatment...
  21. ncbi request reprint Phenomenology of prepubertal and early adolescent bipolar disorder: examples of elated mood, grandiose behaviors, decreased need for sleep, racing thoughts and hypersexuality
    Barbara Geller
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Child Adolesc Psychopharmacol 12:3-9. 2002
    ..g., children do not "max" out credit cards or have four marriages). To address this issue, our group investigated prepubertal and early adolescent age equivalents of adult mania behaviors...
  22. doi request reprint A double-blind, placebo-controlled pilot study of quetiapine for depressed adolescents with bipolar disorder
    Melissa P DelBello
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, 260 Stetson Street, Suite 3200, ML 559, Cincinnati, OH 45219, USA
    Bipolar Disord 11:483-93. 2009
    ..To conduct a pilot study comparing the effects of quetiapine and placebo for the treatment of depressive episodes in adolescents with bipolar I disorder...
  23. ncbi request reprint Comorbid ADHD is associated with altered patterns of neuronal activation in adolescents with bipolar disorder performing a simple attention task
    Caleb M Adler
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    Bipolar Disord 7:577-88. 2005
    ..In this study we utilized functional magnetic resonance imaging (fMRI) to compare activation patterns during performance of a simple attention task between bipolar adolescents with and without ADHD...
  24. doi request reprint Post-traumatic stress symptoms and trauma exposure in youth with first episode bipolar disorder
    Jeffrey R Strawn
    Department of Psychiatry, University of Cincinnati, College of Medicine, Cincinnati, OH 45267 0559, USA
    Early Interv Psychiatry 4:169-73. 2010
    ..To examine the prevalence of trauma exposure as well as the rates and effects of post-traumatic stress disorder (PTSD) in adolescents with bipolar disorder following a first manic episode...
  25. pmc Inhibition and attention in adolescents with nonmanic mood disorders and a high risk for developing mania
    Manpreet K Singh
    Department of Psychiatry, Division of Bipolar Disorders Research, University of Cincinnati, Cincinnati, OH, USA
    J Clin Exp Neuropsychol 31:1-7. 2009
    ..75), and color naming speed (d = 0.88). The results indicate that MD participants exhibit psychomotor disinhibition, marginal cognitive slowing and cautious response biases, but no formal deficits in sustained or selective attention...
  26. pmc Impulsivity across the course of bipolar disorder
    Stephen M Strakowski
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way ML0583, Cincinnati, OH 45267 0583, USA
    Bipolar Disord 12:285-97. 2010
    ..To determine whether abnormalities of impulse control persist across the course of bipolar disorder, thereby representing potential state markers and endophenotypes...
  27. ncbi request reprint Body mass indexes and lipid profiles in hospitalized children and adolescents exposed to atypical antipsychotics
    Nick C Patel
    Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, and Department of Psychiatry, Cincinnati Children s Hospital Medical Center, Ohio 45267 0004, USA
    J Child Adolesc Psychopharmacol 17:303-11. 2007
    ..The purpose of this study was to examine body mass indexes (BMI) and lipid profiles of children and adolescents hospitalized for a psychiatric illness and exposed to an atypical antipsychotic...
  28. pmc Cigarette smoking and impulsivity in bipolar disorder
    Jaimee L Heffner
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH 45219, USA
    Bipolar Disord 14:735-42. 2012
    ..The goal of this study was to examine the association between impulsivity and the initiation or maintenance of smoking in bipolar disorder...
  29. doi request reprint Differential brain activation during response inhibition in bipolar and attention-deficit hyperactivity disorders
    Michael A Cerullo
    Division of Bipolar Disorders Research, Department of Psychiatry, and The Center for Imaging Research, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    Early Interv Psychiatry 3:189-97. 2009
    ..In contrast, we hypothesized that bipolar subjects would show altered brain activation in regions responsible for emotionally homeostasis, including the striatum and amygdala...
  30. ncbi request reprint Voxel-based study of structural changes in first-episode patients with bipolar disorder
    Caleb M Adler
    Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA
    Biol Psychiatry 61:776-81. 2007
    ..In this study, we used VBM to explore structural brain changes in first-episode bipolar patients...
  31. doi request reprint Cerebellar ataxia in youths at risk for bipolar disorder
    Lisa L Giles
    Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Bipolar Disord 10:733-7. 2008
    ..The present study examined cerebellar function in youths who were at familial risk for BD by comparing ataxia battery scores of youths with a bipolar parent to those of healthy youths...
  32. ncbi request reprint Rates, types, and psychosocial correlates of legal charges in adolescents with newly diagnosed bipolar disorder
    Drew H Barzman
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati, OH 45229 3039, USA
    Bipolar Disord 9:339-44. 2007
    ..To examine the rates, types, and psychosocial correlates of legal charges in adolescents with newly diagnosed bipolar disorder (BD)...
  33. pmc Magnetic resonance imaging brain activation in first-episode bipolar mania during a response inhibition task
    Stephen M Strakowski
    Division of Bipolar Disorders Research, Department of Psychiatry, and the Centefor Imaging Research, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Early Interv Psychiatry 2:225-33. 2008
    ..Impulsivity is common in bipolar disorder, especially during mania. Understanding the functional neuroanatomy of response inhibition, one component of impulsivity, might clarify the neural substrate of bipolar disorder...
  34. ncbi request reprint The neurophysiology of childhood and adolescent bipolar disorder
    Melissa P DelBello
    Division of Bipolar Disorder Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    CNS Spectr 11:298-311. 2006
    ....
  35. ncbi request reprint Proton magnetic resonance spectroscopy of the frontal lobe and cerebellar vermis in children with a mood disorder and a familial risk for bipolar disorders
    Kim M Cecil
    Imaging Research Center, Department of Radiology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    J Child Adolesc Psychopharmacol 13:545-55. 2003
    ....
  36. pmc Impulsivity in adolescents with bipolar disorder and/or attention-deficit/hyperactivity disorder and healthy controls as measured by the Barratt Impulsiveness Scale
    Jayasree J Nandagopal
    Department of Psychiatry, University of Cincinnati, Cincinnati, Ohio 45267 0559, USA
    J Child Adolesc Psychopharmacol 21:465-8. 2011
    ....
  37. doi request reprint Pharmacologic treatment of pediatric bipolar disorder
    Jayasree J Nandagopal
    Department of Psychiatry, University of Cincinnati, College of Medicine, 260 Stetson Street, Cincinnati, OH 45267, USA
    Child Adolesc Psychiatr Clin N Am 18:455-69, x. 2009
    ..The complex treatment issues of comorbid BPD and attention deficit/hyperactivity disorder also are addressed...
  38. ncbi request reprint Voxel-based morphometry in adolescents with bipolar disorder: first results
    Marko Wilke
    Imaging Research Center and Department of Psychiatry, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    Psychiatry Res 131:57-69. 2004
    ..VBM confirmed bilaterally larger basal ganglia. Localized gray matter deficits in bipolar subjects were found in the medial temporal lobe, orbito-frontal cortex, and the anterior cingulate, confirming and extending earlier studies...
  39. ncbi request reprint A retrospective chart review of intramuscular ziprasidone for agitation in children and adolescents on psychiatric units: prospective studies are needed
    Drew H Barzman
    Children s Hospital Medical Center, Division of Child and Adolescent Psychiatry, Cincinnati, Ohio 45229 3039, USA
    J Child Adolesc Psychopharmacol 17:503-9. 2007
    ..Our secondary objective was to examine demographic and clinical factors associated with treatment response...
  40. doi request reprint Preventative strategies for early-onset bipolar disorder: towards a clinical staging model
    Robert K McNamara
    Department of Psychiatry, Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    CNS Drugs 24:983-96. 2010
    ..This approach warrants evaluation in prospective longitudinal trials in youth determined to be at ultra-high risk for bipolar I disorder...
  41. pmc Neuroanatomic comparison of bipolar adolescents with and without cannabis use disorders
    Kelly Jarvis
    University of Cincinnati, Division of Bipolar Disorders Research, Department of Psychiatry, Cincinnati, OH 45267 0559, USA
    J Child Adolesc Psychopharmacol 18:557-63. 2008
    ..In this pilot study, we compared brain morphometry between bipolar adolescents with co-occurring cannabis use disorders (CUD) and bipolar adolescents without any substance use disorder...
  42. ncbi request reprint Abnormal FMRI brain activation in euthymic bipolar disorder patients during a counting Stroop interference task
    Stephen M Strakowski
    Center for Imaging Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0583, USA
    Am J Psychiatry 162:1697-705. 2005
    ..Cognitive probes, coupled with neuroimaging, provide an approach toward clarifying the neurophysiology of bipolar disorder...
  43. ncbi request reprint Outcome following a first manic episode: cross-national US and Taiwan comparison
    Stephen M Strakowski
    Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Bipolar Disord 9:820-7. 2007
    ..Therefore, the aim of this study was to identify differential and shared outcome predictors in first-episode manic bipolar patients in Cincinnati, OH, USA and Taipei, Taiwan...
  44. doi request reprint Tolerability of oral ziprasidone in children and adolescents with bipolar mania, schizophrenia, or schizoaffective disorder
    Melissa P DelBello
    University of Cincinnati College of Medicine, Department of Psychiatry, Cincinnati, Ohio 045267, USA
    J Child Adolesc Psychopharmacol 18:491-9. 2008
    ..This study characterizes the tolerability of ziprasidone in children and adolescents with bipolar mania, schizophrenia, or schizoaffective disorder...
  45. ncbi request reprint Ethnic differences in maintenance antipsychotic prescription among adolescents with bipolar disorder
    Nick C Patel
    Department of Psychiatry, University of Cincinnati, and the General Clinical Research Center and Mental Health Service Line, Cincinnati Veterans Affairs Medical Center, Ohio 45267 0004, USA
    J Child Adolesc Psychopharmacol 15:938-46. 2005
    ..The aim of this study was to compare the longitudinal use of psychotropic medications in African-American and Caucasian adolescents with a diagnosis of bipolar disorder following their first psychiatric hospitalization...
  46. doi request reprint Meta-analysis of amygdala volumes in children and adolescents with bipolar disorder
    Jonathan C Pfeifer
    Department of Psychiatry, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    J Am Acad Child Adolesc Psychiatry 47:1289-98. 2008
    ..Therefore, we conducted a meta-analysis summarizing the literature examining amygdala size obtained from magnetic resonance imaging in bipolar youths and adults...
  47. doi request reprint Health-related quality of life as measured by the child health questionnaire in adolescents with bipolar disorder treated with olanzapine
    Brian T Olsen
    Department of Psychiatry and Behavioral Neuroscience, Division of Bipolar Disorder Research, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Compr Psychiatry 53:1000-5. 2012
    ..To examine health-related quality of life (HRQoL) in adolescents with bipolar disorder before and after double-blind treatment with olanzapine or placebo...
  48. pmc Interventions for youth at high risk for bipolar disorder and schizophrenia
    Robert K McNamara
    Division of Bipolar Disorders Research, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    Child Adolesc Psychiatr Clin N Am 21:739-51. 2012
    ..A clinical vignette describing antidepressant-induced manic symptoms in an adolescent with a family history of bipolar disorder is provided...
  49. doi request reprint Neurochemical effects of quetiapine in patients with bipolar mania: a proton magnetic resonance spectroscopy study
    Caleb M Adler
    Division of Bipolar Disorder Research, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH 45219 0516, USA
    J Clin Psychopharmacol 33:528-32. 2013
    ..These data support suggestions that therapeutic effects of quetiapine involve metabolic effects on specific prefrontal regions...
  50. doi request reprint The functional neuroanatomy of bipolar disorder: a consensus model
    Stephen M Strakowski
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Bipolar Disord 14:313-25. 2012
    ....
  51. ncbi request reprint Health-related quality of life in adolescents with bipolar I disorder
    Jennifer Rademacher
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA
    J Child Adolesc Psychopharmacol 17:97-103. 2007
    ..To examine abnormalities in health-related quality of life (HRQOL) and to determine whether pharmacological intervention with divalproex or quetiapine alters HRQOL abnormalities in bipolar adolescents...
  52. doi request reprint Cigarette smoking in the early course of bipolar disorder: association with ages-at-onset of alcohol and marijuana use
    Jaimee L Heffner
    Tri State Tobacco and Alcohol Research Center, University of Cincinnati Genome Research Institute, Cincinnati, OH 45237, USA
    Bipolar Disord 10:838-45. 2008
    ..e., three or more times per week for a month or more)...
  53. pmc Temperament in child offspring of parents with bipolar disorder
    Manpreet K Singh
    Department of Psychiatry, Division of Bipolar Disorders Research, University of Cincinnati, Cincinnati, Ohio 45267 0559, USA
    J Child Adolesc Psychopharmacol 18:589-93. 2008
    ..The aim of this study was to examine the relationship between temperament and psychopathology in child offspring of parents with bipolar disorder...
  54. ncbi request reprint Changes in gray matter volume in patients with bipolar disorder
    Caleb M Adler
    Center for Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Biol Psychiatry 58:151-7. 2005
    ..Voxel based morphometry (VBM) allows a more exploratory analysis without the necessity for predefined anatomic boundaries. In this study we utilized VBM to compare gray matter volume between groups of bipolar and healthy subjects...
  55. ncbi request reprint Obstetrical complications in children at high risk for bipolar disorder
    Manpreet K Singh
    Center for Bipolar Disorders Research, University of Cincinnati College of Medicine, and Cincinnati Children s Hospital Medical Center, Division of Child and Adolescent Psychiatry, Cincinnati, OH 45267 0559, United States
    J Psychiatr Res 41:680-5. 2007
    ..Additionally, within this "at-risk" (AR) sample, we hypothesized that obstetrical complications would be associated with the development of psychiatric disorders...
  56. ncbi request reprint Evidence of white matter pathology in bipolar disorder adolescents experiencing their first episode of mania: a diffusion tensor imaging study
    Caleb M Adler
    Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267 0559, USA
    Am J Psychiatry 163:322-4. 2006
    ..In this study the authors utilized diffusion tensor imaging to study white matter tracts of adolescents in their first episode of mania to address whether abnormalities are present in early bipolar disorder...
  57. doi request reprint Magnetic resonance spectroscopy imaging of lactate in patients with bipolar disorder
    Wen Jang Chu
    Division of Bipolar Disorders Research, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH 45267, United States Center for Imaging Research, University of Cincinnati College of Medicine, Cincinnati, OH 45237, United States School of Energy, Environmental, Biological, and Medical Engineering, University of Cincinnati College of Engineering and Applied Science, Cincinnati, OH 45221, United States
    Psychiatry Res 213:230-4. 2013
    ....
  58. pmc Progression of amygdala volumetric abnormalities in adolescents after their first manic episode
    Samantha M Bitter
    Research, Observation, Service, Education ROSE Program, University of Cincinnati College of Medicine, Cincinnati, OH 45219, USA
    J Am Acad Child Adolesc Psychiatry 50:1017-26. 2011
    ....
  59. pmc The co-occurrence of cigarette smoking and bipolar disorder: phenomenology and treatment considerations
    Jaimee L Heffner
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine Cincinnati Veterans Affairs Medical Center, Cincinnati, OH 45237, USA
    Bipolar Disord 13:439-53. 2011
    ..The goal of this review is to synthesize the literature on the epidemiology, consequences, and treatment of smoking and nicotine dependence among individuals with BD and to delineate a future research agenda...
  60. ncbi request reprint Magnetic resonance imaging analysis of amygdala and other subcortical brain regions in adolescents with bipolar disorder
    Melissa P DelBello
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    Bipolar Disord 6:43-52. 2004
    ..We hypothesized that adolescents with bipolar disorder would exhibit abnormalities in brain regions that are involved in the regulation of mood including the amygdala, globus pallidus, caudate, putamen, and thalamus...
  61. pmc Docosahexaenoic acid supplementation increases prefrontal cortex activation during sustained attention in healthy boys: a placebo-controlled, dose-ranging, functional magnetic resonance imaging study
    Robert K McNamara
    Department of Psychiatry, Center for Imaging Research, Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH 45219 0516, USA
    Am J Clin Nutr 91:1060-7. 2010
    ..However, the effects of DHA supplementation on functional cortical activity in human subjects are unknown...
  62. doi request reprint Progressive neurostructural changes in adolescent and adult patients with bipolar disorder
    Megan E Lisy
    Division of Bipolar Disorder Research, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH 45219 0516, USA
    Bipolar Disord 13:396-405. 2011
    ..In this study we compared baseline and follow-up scans in groups of bipolar disorder and healthy subjects. We hypothesized bipolar disorder subjects would demonstrate significant GMV changes over time...
  63. ncbi request reprint Functional magnetic resonance imaging assessment of cognitive function in childhood-onset systemic lupus erythematosus: a pilot study
    Mark W DiFrancesco
    Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Arthritis Rheum 56:4151-63. 2007
    ....
  64. ncbi request reprint MRI analysis of cerebellar vermal abnormalities in bipolar disorder
    Neil P Mills
    Center for Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Am J Psychiatry 162:1530-2. 2005
    ..The authors sought to expand previous findings of vermal abnormalities in bipolar disorder patients...
  65. ncbi request reprint Pharmacotherapy of children and adolescents with bipolar disorder
    Robert A Kowatch
    Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45267, USA
    Psychiatr Clin North Am 28:385-97. 2005
    ..There are multiple ongoing trials of mood stabilizers and atypical antipsychotics that will provide important controlled data that are currently lacking in the field...
  66. ncbi request reprint Response and remission in adolescent mania: signal detection analyses of the young mania rating scale
    Nick C Patel
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0004, USA
    J Am Acad Child Adolesc Psychiatry 46:628-35. 2007
    ..The purpose of this study was to determine optimal criteria for defining response and remission in adolescents with acute mania...
  67. ncbi request reprint The effectiveness and tolerability of aripiprazole for pediatric bipolar disorders: a retrospective chart review
    Drew H Barzman
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA
    J Child Adolesc Psychopharmacol 14:593-600. 2004
    ..The aim of this retrospective chart review was to evaluate the effectiveness and tolerability of aripiprazole for the treatment of children and adolescents with bipolar disorders...
  68. ncbi request reprint Parametric neurocognitive task design: a pilot study of sustained attention in adolescents with bipolar disorder
    Melissa P DelBello
    Department of Psychiatry, University of Cincinnati College of Medicine, 231 Bethesda Ave, P O Box 670559, Cincinnati, OH 45267 0559, USA
    J Affect Disord 82:S79-88. 2004
    ..Additionally, we hypothesized that the groups would exhibit a similar decline in task performance as level of task difficulty increased and that within each level of task difficulty there would be similar performance among groups...
  69. ncbi request reprint Phenomenology associated with age at onset in patients with bipolar disorder at their first psychiatric hospitalization
    Nick C Patel
    College of Pharmacy, University of Cincinnati, Cincinnati, OH 45267 0004, USA
    Bipolar Disord 8:91-4. 2006
    ..To compare the clinical presentation of patients with early-onset (age <18 years) and typical-onset (age 20-30 years) bipolar disorder at the time of first hospitalization...
  70. ncbi request reprint Evidence of anterior temporal atrophy in college-level soccer players
    John Adams
    Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Clin J Sport Med 17:304-6. 2007
    ..In this study, we employed newer imaging techniques to examine brain changes in younger soccer players. We hypothesized that soccer players would demonstrate evidence of neurologic injury consistent with multiple frontal head blows...
  71. ncbi request reprint Medical management of pediatric mood disorders
    Manpreet K Singh
    Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, OH 45267 0559, USA
    Pediatr Ann 36:552-63. 2007
  72. ncbi request reprint Adjunctive topiramate treatment for pediatric bipolar disorder: a retrospective chart review
    Melissa P DelBello
    Bipolar and Psychiatric Disorders Research Program, Department of Psychiatry, University of Cincinnati, College of Medicine, Cincinnati, Ohio 45267, USA
    J Child Adolesc Psychopharmacol 12:323-30. 2002
    ..The objective of this study was to evaluate the effectiveness, safety, and tolerability of the anticonvulsant agent, topiramate, as adjunctive treatment for children and adolescents with bipolar disorders...
  73. doi request reprint Retrospective age at onset of bipolar disorder and outcome during two-year follow-up: results from the STEP-BD study
    Roy H Perlis
    Bipolar Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, ACC 812 15 Parkman Street, Boston, MA 02114, USA
    Bipolar Disord 11:391-400. 2009
    ..Symptoms of bipolar disorder are increasingly recognized among children and adolescents, but little is known about the course of bipolar disorder among adults who experience childhood onset of symptoms...
  74. ncbi request reprint Rates and predictors of developing a manic or hypomanic episode 1 to 2 years following a first hospitalization for major depression with psychotic features
    Melissa P DelBello
    The Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    J Child Adolesc Psychopharmacol 13:173-85. 2003
    ....
  75. ncbi request reprint A pilot controlled trial of topiramate for mania in children and adolescents with bipolar disorder
    Melissa P DelBello
    Center for Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    J Am Acad Child Adolesc Psychiatry 44:539-47. 2005
    ..To assess the efficacy of topiramate monotherapy for acute mania in children and adolescents with bipolar disorder type I...
  76. pmc Effects of age, sex, and independent life events on amygdala and nucleus accumbens volumes in child bipolar I disorder
    Barbara Geller
    Department of Psychiatry, Washington University in St Louis, St Louis, Missouri 63110 1093, USA
    Biol Psychiatry 65:432-7. 2009
    ..Relationships between environment and cortical-limbic-striatal pathways are not well-researched in child bipolar I disorder (BP-I)...
  77. ncbi request reprint Family environment in families with versus families without parental bipolar disorder: a preliminary comparison study
    Soledad Romero
    Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    Bipolar Disord 7:617-22. 2005
    ..To compare family environmental characteristics of families with at least one bipolar parent and families with parents without any Axis I disorder...
  78. ncbi request reprint Co-occurrence of bipolar and attention-deficit hyperactivity disorders in children
    Manpreet K Singh
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, 231 Bethesda Avenue, Cincinnati, OH 45267, USA
    Bipolar Disord 8:710-20. 2006
    ..g., psychostimulants) lead to the onset of pediatric BPD; and (iv) ADHD and BPD share an underlying biological etiology (i.e., a common familial or genetic risk or underlying neurophysiology)...
  79. ncbi request reprint Severity of bipolarity in hospitalized manic adolescents with history of stimulant or antidepressant treatment
    Cesar A Soutullo
    University of Cincinnati, Department of Psychiatry, Biological Psychiatry and Psychotic and Bipolar Disorders Research Programs, PO Box 670559, 231 Bethesda Avenue, Cincinnati, OH 45267 0559, USA
    J Affect Disord 70:323-7. 2002
    ..Childhood bipolarity (BP) and ADHD frequently co-occur, these children often receive stimulants...
  80. ncbi request reprint DSM-IV mania symptoms in a prepubertal and early adolescent bipolar disorder phenotype compared to attention-deficit hyperactive and normal controls
    Barbara Geller
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Child Adolesc Psychopharmacol 12:11-25. 2002
    ....
  81. ncbi request reprint Frontal lobe differences in bipolar disorder as determined by proton MR spectroscopy
    Kim M Cecil
    Imaging Research Center, Department of Radiology, Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Bipolar Disord 4:357-65. 2002
    ..Patients with bipolar disorder having a manic or mixed episode were hypothesized to demonstrate metabolic abnormalities within the frontal lobe...
  82. ncbi request reprint Pediatric bipolar disorder: emerging diagnostic and treatment approaches
    Robert A Kowatch
    Department of Psychiatry and Pediatrics, University of Cincinnati Medical Center and Cincinnati Children s Hospital Medical Center, MSB 7261, PO Box 670559, Cincinnati, OH 45267 0559, USA
    Child Adolesc Psychiatr Clin N Am 15:73-108. 2006
    ..It is becoming apparent that bipolar disorder is often a chronic disorder in children and adolescents, much like diabetes, and is best managed with a combination of medications and psychosocial therapy...
  83. ncbi request reprint Open-label lithium for the treatment of adolescents with bipolar depression
    Nick C Patel
    College of Pharmacy and Department of Psychiatry, University of Cincinnati, OH 45267 0004, USA
    J Am Acad Child Adolesc Psychiatry 45:289-97. 2006
    ..We hypothesized that patients receiving open-label treatment with lithium during a 6-week period would experience a statistically and clinically significant decrease in depressive symptoms and tolerate lithium treatment fairly well...
  84. ncbi request reprint Ventricular and periventricular structural volumes in first- versus multiple-episode bipolar disorder
    Stephen M Strakowski
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Am J Psychiatry 159:1841-7. 2002
    ..In addition, it is unknown whether ventriculomegaly in bipolar disorder reflects acquired volume loss or underdevelopment of periventricular structures...
  85. ncbi request reprint Concurrent tracking of alcohol use and bipolar disorder symptoms
    David E Fleck
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Bipolar Disord 8:338-44. 2006
    ..The primary aim of this analysis was to examine concurrent symptom tracking and how the relative onsets of AUD and BD influence the concurrent tracking of symptoms...
  86. ncbi request reprint Neuroanatomic characterization of schizoaffective disorder using MRI: a pilot study
    Glen E Getz
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Schizophr Res 55:55-9. 2002
    ..Patients diagnosed with SCA exhibited regional abnormalities on the striatum that resemble those seen in BPD. This study suggests that SCA has some neuroanatomical characteristics similar to BPD...
  87. ncbi request reprint Parental reports of executive dysfunction in adolescents with bipolar disorder
    Paula K Shear
    Department of Psychology, University of Cincinnati, OH 45221, USA
    Child Neuropsychol 8:285-95. 2002
    ..The findings suggest that adolescents with BPD have functional deficits on tasks requiring executive functioning skills that are not explicable solely on the basis of comorbid ADHD...
  88. ncbi request reprint Pharmacological interventions for bipolar youth: developmental considerations
    Melissa P DelBello
    Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
    Dev Psychopathol 18:1231-46. 2006
    ..Recently, studies have begun to characterize prodromal manifestations of bipolar disorder and identify early intervention strategies for treating children and adolescents with an elevated risk for developing bipolar disorder...
  89. ncbi request reprint Olanzapine for the treatment of bipolar disorder in children and adolescents
    Jeffrey R Strawn
    Department of Psychiatry, University of Cincinnati, Box 670559, Cincinnati, OH 45267 0559, USA
    Expert Opin Pharmacother 9:467-74. 2008
    ....
  90. ncbi request reprint A preliminary FMRI study of sustained attention in euthymic, unmedicated bipolar disorder
    Stephen M Strakowski
    Bipolar and Psychotic Disorders Research Program, University of Cincinnati College of Medicine, OH 45267 0583, USA
    Neuropsychopharmacology 29:1734-40. 2004
    ..Since the differences occurred in euthymia, they may represent trait, rather than state, abnormalities of brain function in bipolar disorder...
  91. ncbi request reprint Ethnic differences in symptom presentation of youths with bipolar disorder
    Nick C Patel
    The College of Pharmacy, University of Cincinnati, OH 45267 0004, USA
    Bipolar Disord 8:95-9. 2006
    ..To compare symptom profiles of African-American and white adolescents with a diagnosis of bipolar disorder...
  92. ncbi request reprint Volumetric MRI studies of mood disorders: do they distinguish unipolar and bipolar disorder?
    Stephen M Strakowski
    Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
    Bipolar Disord 4:80-8. 2002
    ..This hypothesis remains speculative as much more research is needed to specifically examine how morphometric brain abnormalities translate into the neurophysiologic deficits that produce mood disorders...
  93. doi request reprint Morphometric magnetic resonance imaging in psychiatry
    David E Fleck
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati, Cincinnati, OH 45267 0559, USA
    Top Magn Reson Imaging 19:131-42. 2008
    ..However, advances in outcome and treatment monitoring show considerably more promise for rapid application in psychiatry...
  94. ncbi request reprint A double-blind, randomized, placebo-controlled study of quetiapine as adjunctive treatment for adolescent mania
    Melissa P DelBello
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    J Am Acad Child Adolesc Psychiatry 41:1216-23. 2002
    ..It was hypothesized that DVP in combination with quetiapine would be more effective than DVP alone for treating mania associated with adolescent bipolar disorder. Furthermore, it was hypothesized that quetiapine would be well tolerated...
  95. ncbi request reprint Differential prescription of maintenance antipsychotics to African American and white patients with new-onset bipolar disorder
    David E Fleck
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    J Clin Psychiatry 63:658-64. 2002
    ..African American patients may be at increased risk because excess antipsychotic prescription appears to be common in this population, although this issue has not been longitudinally studied in bipolar disorder...
  96. ncbi request reprint The use of mood stabilizers and atypical antipsychotics in children and adolescents with bipolar disorders
    Robert A Kowatch
    Department of Psychiatry, Cincinnati Children s Hospital Medical Center, University of Cincinnati Medical Center, Ohio 45267, USA
    CNS Spectr 8:273-80. 2003
    ....
  97. ncbi request reprint Revisiting depressive-prone bipolar disorder: polarity of initial mood episode and disease course among bipolar I systematic treatment enhancement program for bipolar disorder participants
    Roy H Perlis
    Bipolar Clinical and Research Program, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Biol Psychiatry 58:549-53. 2005
    ..We examined the hypothesis that a first depressive rather than manic episode in bipolar disorder might herald a subsequent course notable for greater burden of depressive symptoms...
  98. ncbi request reprint Anterior cingulate subregion volumes and executive function in bipolar disorder
    Molly E Zimmerman
    Department of Psychiatry and Human Behavior, Brown Medical School, Providence, RI 02912, USA
    Bipolar Disord 8:281-8. 2006
    ....
  99. ncbi request reprint Topiramate for co-occurring bipolar disorder and disruptive behavior disorders
    Drew H Barzman
    Am J Psychiatry 163:1451-2. 2006
  100. ncbi request reprint Long-term implications of early onset in bipolar disorder: data from the first 1000 participants in the systematic treatment enhancement program for bipolar disorder (STEP-BD)
    Roy H Perlis
    Partners Bipolar Treatment Center at Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Biol Psychiatry 55:875-81. 2004
    ..Early onset of mood symptoms in bipolar disorder has been associated with poor outcome in many studies; however, the factors that might contribute to poor outcome have not been adequately investigated...
  101. doi request reprint Temporal change in N-acetyl-aspartate concentrations in adolescents with bipolar depression treated with lithium
    Nick C Patel
    College of Pharmacy, University of Georgia, Medical College of Georgia, Augusta, Georgia 30912 2450, USA
    J Child Adolesc Psychopharmacol 18:132-9. 2008
    ..This proton magnetic resonance spectroscopy (1H MRS) study identified the in vivo effects of lithium on N-acetyl-aspartate (NAA) concentrations in adolescent bipolar depression...