John O Delancey

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. ncbi request reprint The pathophysiology of stress urinary incontinence in women and its implications for surgical treatment
    J O DeLancey
    Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, USA
    World J Urol 15:268-74. 1997
  2. pmc Stress urinary incontinence: relative importance of urethral support and urethral closure pressure
    John O L Delancey
    Department of Obstetrics and Gynecology, Pelvic Floor Research Group, University of Michigan, Ann Arbor, Michigan, USA
    J Urol 179:2286-90; discussion 2290. 2008
  3. pmc Why do women have stress urinary incontinence?
    John O L Delancey
    Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan, USA
    Neurourol Urodyn 29:S13-7. 2010
  4. ncbi request reprint Pathophysiology of adult urinary incontinence
    John O L Delancey
    Department of Obstetrics and Gynecology, Institute of Gerontology, University of Michigan at Ann Arbor, 48109 0276, USA
    Gastroenterology 126:S23-32. 2004
  5. ncbi request reprint Comparison of levator ani muscle defects and function in women with and without pelvic organ prolapse
    John O L Delancey
    Department of Obstetrics and Gynecology, Department of Biomechanical Engineering, Institute of Gerontology, School of Nursing, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA
    Obstet Gynecol 109:295-302. 2007
  6. ncbi request reprint Size of the urogenital hiatus in the levator ani muscles in normal women and women with pelvic organ prolapse
    J O DeLancey
    Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor 48109 0216, USA
    Obstet Gynecol 91:364-8. 1998
  7. ncbi request reprint Internal and external anal sphincter anatomy as it relates to midline obstetric lacerations
    J O DeLancey
    Department of Obstetrics and Gynecology, University of Michigan Medical Center, Ann Arbor, USA
    Obstet Gynecol 90:924-7. 1997
  8. pmc Vaginal birth and de novo stress incontinence: relative contributions of urethral dysfunction and mobility
    John O L Delancey
    Department of Obstetrics and Gynecology, Pelvic Floor Research Group, and School of Nursing, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA
    Obstet Gynecol 110:354-62. 2007
  9. ncbi request reprint Fecal and urinary incontinence after vaginal delivery with anal sphincter disruption in an obstetrics unit in the United States
    Dee E Fenner
    Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA
    Am J Obstet Gynecol 189:1543-9; discussion 1549-50. 2003
  10. pmc A 3D finite element model of anterior vaginal wall support to evaluate mechanisms underlying cystocele formation
    Luyun Chen
    Biomechanics Research Laboratory, Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109 2125, USA
    J Biomech 42:1371-7. 2009

Research Grants

Detail Information

Publications88

  1. ncbi request reprint The pathophysiology of stress urinary incontinence in women and its implications for surgical treatment
    J O DeLancey
    Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, USA
    World J Urol 15:268-74. 1997
    ..That operations cure stress incontinence without altering nerve or muscle function should not be misinterpreted as indicating that these factors are unimportant...
  2. pmc Stress urinary incontinence: relative importance of urethral support and urethral closure pressure
    John O L Delancey
    Department of Obstetrics and Gynecology, Pelvic Floor Research Group, University of Michigan, Ann Arbor, Michigan, USA
    J Urol 179:2286-90; discussion 2290. 2008
    ..To our knowledge the relative importance of these 2 factors has not been assessed in properly controlled studies...
  3. pmc Why do women have stress urinary incontinence?
    John O L Delancey
    Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan, USA
    Neurourol Urodyn 29:S13-7. 2010
    ..Improving our understanding of factors affecting urethral closure may lead to novel treatments targeting the urethra and improved understanding of the small but persistent failure rate of current surgery...
  4. ncbi request reprint Pathophysiology of adult urinary incontinence
    John O L Delancey
    Department of Obstetrics and Gynecology, Institute of Gerontology, University of Michigan at Ann Arbor, 48109 0276, USA
    Gastroenterology 126:S23-32. 2004
    ..Activation of the levator muscle during abdominal pressurization is important to this stabilization process. The integrity of the connection between the vaginal wall and tendinous arch also plays an important role...
  5. ncbi request reprint Comparison of levator ani muscle defects and function in women with and without pelvic organ prolapse
    John O L Delancey
    Department of Obstetrics and Gynecology, Department of Biomechanical Engineering, Institute of Gerontology, School of Nursing, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA
    Obstet Gynecol 109:295-302. 2007
    ..To compare levator ani defects and pelvic floor function among women with prolapse and controls...
  6. ncbi request reprint Size of the urogenital hiatus in the levator ani muscles in normal women and women with pelvic organ prolapse
    J O DeLancey
    Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor 48109 0216, USA
    Obstet Gynecol 91:364-8. 1998
    ..Compare urogenital hiatus size in normal women and women with pelvic organ prolapse...
  7. ncbi request reprint Internal and external anal sphincter anatomy as it relates to midline obstetric lacerations
    J O DeLancey
    Department of Obstetrics and Gynecology, University of Michigan Medical Center, Ann Arbor, USA
    Obstet Gynecol 90:924-7. 1997
    ..To examine the anatomy of the internal and external anal sphincters in the area of midline obstetric lacerations, to gain insight into sphincter damage and repair...
  8. pmc Vaginal birth and de novo stress incontinence: relative contributions of urethral dysfunction and mobility
    John O L Delancey
    Department of Obstetrics and Gynecology, Pelvic Floor Research Group, and School of Nursing, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA
    Obstet Gynecol 110:354-62. 2007
    ..To evaluate the relative contributions of urethral mobility and urethral function to stress incontinence...
  9. ncbi request reprint Fecal and urinary incontinence after vaginal delivery with anal sphincter disruption in an obstetrics unit in the United States
    Dee E Fenner
    Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA
    Am J Obstet Gynecol 189:1543-9; discussion 1549-50. 2003
    ....
  10. pmc A 3D finite element model of anterior vaginal wall support to evaluate mechanisms underlying cystocele formation
    Luyun Chen
    Biomechanics Research Laboratory, Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109 2125, USA
    J Biomech 42:1371-7. 2009
    ....
  11. pmc Graphic integration of causal factors of pelvic floor disorders: an integrated life span model
    John O L Delancey
    Pelvic Floor Research Group, University of Michigan, Ann Arbor, MI, USA
    Am J Obstet Gynecol 199:610.e1-5. 2008
    ..This graphical tool accounts for changes in different phases to be integrated to form a disease model to help assess the overlap of different causal factors...
  12. pmc The relationship between superior attachment points for anterior wall mesh operations and the upper vagina using a 3-dimensional magnetic resonance model in women with normal support
    Kindra A Larson
    Pelvic Floor Research Group, Division of Gynecology, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA
    Am J Obstet Gynecol 200:554.e1-6. 2009
    ..We examined structural relationships between anterior mesh kit suspension points and the upper vagina in women with normal support...
  13. pmc Distribution of pelvic organ support measures in a population-based sample of middle-aged, community-dwelling African American and white women in southeastern Michigan
    Elisa R Trowbridge
    Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, MI, USA
    Am J Obstet Gynecol 198:548.e1-6. 2008
    ....
  14. pmc The association of Incontinence Symptom Index scores with urethral function and support
    Christina Lewicky-Gaupp
    Pelvic Floor Research Group, Division of Gynecology, Department of Obstetrics and Gynecology, University of Michigan School of Medicine, Ann Arbor, MI, USA
    Am J Obstet Gynecol 199:680.e1-5. 2008
    ..The objective of this study was to establish categories of symptom severity based on Incontinence Symptom Index (ISI) scores and to show how these categories are associated with urethral function and support...
  15. doi request reprint Racial differences in fecal incontinence in community-dwelling women from the EPI study
    Mitchell B Berger
    Pelvic Floor Research Group, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI 48109 5276, USA
    Female Pelvic Med Reconstr Surg 19:169-74. 2013
    ..The goal of this study was to estimate the prevalence of FI, and to secondarily identify demographic, lifestyle, and medical factors associated with FI, especially with regard to race...
  16. pmc Biomechanical analyses of the efficacy of patterns of maternal effort on second-stage progress
    Kuo Cheng Lien
    Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan 48109 2125, USA
    Obstet Gynecol 113:873-80. 2009
    ..To develop and use a biomechanical computer model to simulate the effect of varying the timing of voluntary maternal pushes during uterine contraction on second-stage labor duration...
  17. pmc Urethral circular smooth muscle in young and old women
    Amy Clobes
    Department of Obstetrics and Gynecology, Women s Hospital, University of Michigan, Ann Arbor, MI 48109, USA
    Am J Obstet Gynecol 198:587.e1-5. 2008
    ..The purpose of this study was to determine whether thickness, fiber count, and density of urethral circular smooth muscle (CSM) differ in young and old women...
  18. pmc Self-perceived natural history of pelvic organ prolapse described by women presenting for treatment
    Christina Lewicky-Gaupp
    Pelvic Floor Research Group, Division of Gynecology, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA
    Int Urogynecol J Pelvic Floor Dysfunct 20:927-31. 2009
    ..This study aimed to describe the self-perceived natural history of pelvic organ prolapse (POP) in women seeking care...
  19. pmc Posterior compartment anatomy as seen in magnetic resonance imaging and 3-dimensional reconstruction from asymptomatic nulliparas
    Yvonne Hsu
    Pelvic Floor Research Group and Division of Gynecology, Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, MI, USA
    Am J Obstet Gynecol 198:651.e1-7. 2008
    ..The objective of the study was to identify characteristic anatomical features of the posterior compartment using magnetic resonance (MR) cross-sectional anatomy and 3-dimensional (3-D) modeling...
  20. pmc Clarification and confirmation of the Knack maneuver: the effect of volitional pelvic floor muscle contraction to preempt expected stress incontinence
    Janis M Miller
    School of Nursing, University of Michigan, Ann Arbor, MI, USA
    Int Urogynecol J Pelvic Floor Dysfunct 19:773-82. 2008
    ..001). This study confirms the effect from the Knack maneuver as immediate and provides a partial explanation for early response to widely applied pelvic muscle training regimens in women with stress incontinence...
  21. pmc Magnetic resonance imaging-based three-dimensional model of anterior vaginal wall position at rest and maximal strain in women with and without prolapse
    Kindra A Larson
    Pelvic Floor Research Group, University of Michigan, Ann Arbor, MI, USA
    Int Urogynecol J 21:1103-9. 2010
    ..This paper describes a novel three-dimensional technique to examine the vagina and its relationship to pelvic sidewalls at rest and Valsalva...
  22. ncbi request reprint Are persistent or recurrent symptoms of urinary incontinence after surgery associated with adverse effects on sexual activity or function?
    Daniel M Morgan
    Department of Obstetrics and Gynecology, Women s Hospital L4000, University of Michigan, Ann Arbor, MI 48109, USA
    Int Urogynecol J Pelvic Floor Dysfunct 19:509-15. 2008
    ..42, p < 0.001). The severity of postoperative recurrent or persistent UI is associated with a lower probability of being sexually active and an adverse effect on sexual function...
  23. pmc Symptoms of anal incontinence and difficult defecation among women with prolapse and a matched control cohort
    Daniel M Morgan
    Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, MI 48109 0276, USA
    Am J Obstet Gynecol 197:509.e1-6. 2007
    ....
  24. pmc "The cough game": are there characteristic urethrovesical movement patterns associated with stress incontinence?
    Christina Lewicky-Gaupp
    Division of Gynecology, Pelvic Floor Research Group, Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, MI, USA
    Int Urogynecol J Pelvic Floor Dysfunct 20:171-5. 2009
    ..0 +/- 7.3%. Inter-rater reliability, evaluated by Cohen's kappa statistic, averaged 0.47 [95% CI 0.40-0.50]. Experts could not identify a pattern of urethrovesical movement characteristic of SUI on ultrasound...
  25. pmc Urethral sphincter morphology and function with and without stress incontinence
    Daniel M Morgan
    University of Michigan, Ann Arbor, Michigan, USA
    J Urol 182:203-9. 2009
    ..Using magnetic resonance images we analyzed the relationship between urethral sphincter anatomy, urethral function and pelvic floor function...
  26. pmc Do repetitive Valsalva maneuvers change maximum prolapse on dynamic MRI?
    Julie A Tumbarello
    Pelvic Floor Research Group, University of Michigan, Ann Arbor, MI, USA
    Int Urogynecol J 21:1247-51. 2010
    ..This study seeks to quantify differences in anterior vaginal wall prolapse during sequential Valsalva attempts on dynamic magnetic resonance imaging (MRI)...
  27. pmc Anatomy of the perineal membrane as seen in magnetic resonance images of nulliparous women
    Catherine J Brandon
    Pelvic Floor Research Group, University of Michigan, Ann Arbor, MI, USA
    Am J Obstet Gynecol 200:583.e1-6. 2009
    ..Recent cadaver research demonstrates the perineal membrane's ventral and dorsal portions and close relationship to the levator ani muscle. This study seeks to show these relationships in women by magnetic resonance (MR) images...
  28. pmc Structure of the perineal membrane in females: gross and microscopic anatomy
    Tamara A Stein
    Division of Anatomical Sciences, Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, Michigan 48109 0608, USA
    Obstet Gynecol 111:686-93. 2008
    ..To re-examine the anatomy of the perineal membrane and its anatomical relationships in whole-pelvis and histologic serial section as well as gross anatomical dissection...
  29. pmc Differences in continence system between community-dwelling black and white women with and without urinary incontinence in the EPI study
    John O L Delancey
    Pelvic Floor Research Group, University of Michigan, Ann Arbor, MI, USA
    Am J Obstet Gynecol 202:584.e1-584.e12. 2010
    ..We sought to compare continence system function of black and white women in a population-based sample...
  30. pmc Anal sphincter structure and function relationships in aging and fecal incontinence
    Christina Lewicky-Gaupp
    Pelvic Floor Research Group, Division of Gynecology, Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, MI, USA
    Am J Obstet Gynecol 200:559.e1-5. 2009
    ..The objective of the study was to determine the effect of aging and continence status on the structure and function of the external (EAS) and internal (IAS) anal sphincters..
  31. pmc Levator defects affect perineal position independently of prolapse status
    Natalie A Clark
    Pelvic Floor Research Group, University of Michigan, Ann Arbor, MI, USA
    Am J Obstet Gynecol 203:595.e17-22. 2010
    ..The purpose of this study was to determine the effect of levator defects on perineal position and movement irrespective of prolapse status...
  32. pmc Comparison of bony dimensions at the level of the pelvic floor in women with and without pelvic organ prolapse
    Tamara A Stein
    Pelvic Floor Research Group, University of Michigan, Ann Arbor, MI Division of Anatomical Science, Office of Medical Eduction, University of Michigan, Ann Arbor, MI, USA
    Am J Obstet Gynecol 200:241.e1-5. 2009
    ..We sought to compare bony pelvis dimensions at the level of pelvic support in women with and without pelvic organ prolapse (POP)...
  33. ncbi request reprint Fascial and muscular abnormalities in women with urethral hypermobility and anterior vaginal wall prolapse
    John O L Delancey
    Department of Obstetrics and Gynecology, University of Michigan Medical Center, Ann Arbor, 48109 0276, USA
    Am J Obstet Gynecol 187:93-8. 2002
    ..Our purpose was to assess the structural integrity of individual elements of the urethral and anterior vaginal wall support system...
  34. pmc Outcomes following vaginal prolapse repair and mid urethral sling (OPUS) trial--design and methods
    John Wei
    Department of Urology, University of Michigan, Ann Arbor, Michigan, USA
    Clin Trials 6:162-71. 2009
    ....
  35. pmc The appearance of levator ani muscle abnormalities in magnetic resonance images after vaginal delivery
    John O L Delancey
    University of Michigan, Ann Arbor, Michigan 48109 0276, USA
    Obstet Gynecol 101:46-53. 2003
    ..To describe the appearance and occurrence of abnormalities in the levator ani muscle seen on magnetic resonance imaging (MRI) in nulliparous women and in women after their first vaginal birth...
  36. pmc Interaction among apical support, levator ani impairment, and anterior vaginal wall prolapse
    Luyun Chen
    Department of Biomedical Engineering, University of Michigan, Ann Arbor, 48109 2125, USA
    Obstet Gynecol 108:324-32. 2006
    ..To use a biomechanical model to explore how impairment of the pubovisceral portion of the levator ani muscle, the apical vaginal suspension complex, or both might interact to affect anterior vaginal wall prolapse severity...
  37. ncbi request reprint Spasticity of the pelvic floor mimicking an obstructive anomaly
    Elisabeth H Quint
    Department of Obstetrics and Gynecology, University of Michigan Health Systems, Ann Arbor, Michigan 48109 0276, USA
    J Pediatr Adolesc Gynecol 16:83-5. 2003
    ..The study objective is to report two unusual cases of a spastic pelvic floor leading to urine collecting in the vagina and mimicking an outflow obstruction...
  38. ncbi request reprint Functional anatomy of the female pelvic floor
    James A Ashton-Miller
    Department of Mechanical Engineering, Biomechanics Engineering and Institute of Gerontology, G G Brown 3208, University of Michigan, Ann Arbor, MI 48109 2125, USA
    Ann N Y Acad Sci 1101:266-96. 2007
    ..3 and the pudendal nerve under strains of up to 33%, respectively. Research is needed to better identify the pathomechanics of these conditions...
  39. pmc Comparison of the main body of the external anal sphincter muscle cross-sectional area between women with and without prolapse
    Yvonne Hsu
    Department of Obstetrics and Gynecology, University of Michigan, L4100 Women s Hospital 1500 E Medical Center Drive, Ann Arbor, MI 48109 0276, USA
    Int Urogynecol J Pelvic Floor Dysfunct 18:1303-8. 2007
    ..However, women with both prolapse and a major levator ani defect had larger external anal sphincter CSAs compared to prolapse patients without levator ani defects...
  40. pmc Pelvic structure and function at 1 month compared to 7 months by dynamic magnetic resonance after vaginal birth
    Aisha A Yousuf
    Department of Obstetrics and Gynecology, University of Michigan Hospital, Ann Arbor, MI, USA
    Am J Obstet Gynecol 201:514.e1-7. 2009
    ..We sought to determine whether changes exist in location and movement of pelvic floor structures at 1 and 7 months postpartum...
  41. pmc Levator ani defect status and lower urinary tract symptoms in women with pelvic organ prolapse
    Daniel M Morgan
    Division of Gynecology, Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, MI, USA
    Int Urogynecol J 21:47-52. 2010
    ..Among women with pelvic organ prolapse, compare rates of lower urinary tract symptoms by levator ani defect (LAD) status...
  42. pmc Magnetic resonance imaging and 3-dimensional analysis of external anal sphincter anatomy
    Yvonne Hsu
    Pelvic Floor Research Group, Division of Gynecology, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan 48109 0276, USA
    Obstet Gynecol 106:1259-65. 2005
    ....
  43. pmc Pelvic floor consequences of cesarean delivery on maternal request in women with a single birth: a cost-effectiveness analysis
    Xiao Xu
    Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan 48109, USA
    J Womens Health (Larchmt) 19:147-60. 2010
    ....
  44. ncbi request reprint Does vaginal closure force differ in the supine and standing positions?
    Daniel M Morgan
    Department of Obstetrics and Gynecology, Pelvic Floor Research Group, University of Michigan Medical School, Ann Arbor 48109, USA
    Am J Obstet Gynecol 192:1722-8. 2005
    ....
  45. ncbi request reprint Pudendal nerve stretch during vaginal birth: a 3D computer simulation
    Kuo Cheng Lien
    Department of Mechanical Engineering, University of Michigan, Ann Arbor 48109 2125, USA
    Am J Obstet Gynecol 192:1669-76. 2005
    ..The purpose of this study was to determine the increase in pudendal nerve branch lengths using a 3D computer model of vaginal delivery...
  46. ncbi request reprint The hidden epidemic of pelvic floor dysfunction: achievable goals for improved prevention and treatment
    John O L Delancey
    Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor 48109 0276, USA
    Am J Obstet Gynecol 192:1488-95. 2005
    ..With an integrated approach to this problem over the next 20 years, it should be possible to achieve these goals and reduce the suffering for more than 100,000 afflicted women...
  47. pmc Self-report of difficult defecation is associated with overactive bladder symptoms
    Anne Cameron
    Department of Urology, University of Michigan, Ann Arbor, Michigan 48109 5330, USA
    Neurourol Urodyn 29:1290-4. 2010
    ..It was our objective to assess lower urinary tract symptoms (LUTS) in women who report difficult defecation (DD)...
  48. pmc Childbirth and pelvic floor dysfunction: an epidemiologic approach to the assessment of prevention opportunities at delivery
    Divya A Patel
    OB GYN Health Services Research Group, Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, USA
    Am J Obstet Gynecol 195:23-8. 2006
    ....
  49. pmc Levator plate angle in women with pelvic organ prolapse compared to women with normal support using dynamic MR imaging
    Yvonne Hsu
    Department of Obstetrics and Gynecology, School of Public Health, University of Michigan, Ann Arbor, MI, USA
    Am J Obstet Gynecol 194:1427-33. 2006
    ..The purpose of this study was to determine whether the levator plate is (1) horizontal in women with normal support, (2) different between women with and without prolapse, (3) related to levator hiatus and perineal body descent...
  50. pmc Appearance of the levator ani muscle subdivisions in magnetic resonance images
    Rebecca U Margulies
    University of Michigan, Ann Arbor, Michigan 48109 0276, USA
    Obstet Gynecol 107:1064-9. 2006
    ..Identify and describe the separate appearance of 5 levator ani muscle subdivisions seen in axial, coronal, and sagittal magnetic resonance imaging (MRI) scan planes...
  51. pmc Fecal incontinence in pregnancy and post partum
    Cynthia Brincat
    Pelvic Floor Research Group, University of Michigan, Ann Arbor, MI, USA
    Int J Gynaecol Obstet 106:236-8. 2009
    ..To assess the prevalence of fecal incontinence (FI) during pregnancy and post partum, and to determine any associations with demographic and birth variables...
  52. ncbi request reprint Effects of aging on lower urinary tract and pelvic floor function in nulliparous women
    Elisa Rodriguez Trowbridge
    Division of Gynecology, Department of Obstetrics and Gynecology, University of Michigan Medical Center, University of Michigan, Ann Arbor, Michigan 48109, USA
    Obstet Gynecol 109:715-20. 2007
    ..To evaluate the effects of aging, independent of parity, on pelvic organ and urethral support, urethral function, and levator function in a sample of nulliparous women...
  53. ncbi request reprint Can women without visible pubococcygeal muscle in MR images still increase urethral closure pressures?
    Janis M Miller
    Department of Obstetrics and Gynecology, School of Nursing, University of Michigan, Ann Arbor, USA
    Am J Obstet Gynecol 191:171-5. 2004
    ..The purpose of this study was to determine if the ability to increase maximum urethral closure pressure (MUCP) with a pelvic muscle contraction is impaired in women without pubococcygeal muscle (PCM)...
  54. ncbi request reprint Comparative analysis of urinary incontinence severity after autologous fascia pubovaginal sling, pubovaginal sling and tension-free vaginal tape
    Daniel M Morgan
    Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan 48109 0759, USA
    J Urol 177:604-8; discussion 608-9. 2007
    ..We explored the relative effectiveness of the autologous fascia pubovaginal sling, Pelvicol pubovaginal sling and Gynecare TVT on self-reported postoperative urinary incontinence...
  55. pmc On the biomechanics of vaginal birth and common sequelae
    James A Ashton-Miller
    Biomechanics Research Laboratory, Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA
    Annu Rev Biomed Eng 11:163-76. 2009
    ..A conceptual model suggests how these injuries may lead to the most common form of pelvic organ prolapse, a cystocele...
  56. pmc Interrater reliability of assessing levator ani muscle defects with magnetic resonance images
    Daniel M Morgan
    Pelvic Floor Research Group, Department of Obstetrics and Gynecology, University of Michigan, 1500 E Medical Center Drive, Ann Arbor, MI 48109 0276, USA
    Int Urogynecol J Pelvic Floor Dysfunct 18:773-8. 2007
    ..Examiner pairs discriminated injury similarly when defect status was categorized as normal/none, minor, or major...
  57. ncbi request reprint Quantification of levator ani cross-sectional area differences between women with and those without prolapse
    Yvonne Hsu
    University of Michigan, Ann Arbor, Michigan, USA
    Obstet Gynecol 108:879-83. 2006
    ..Compare levator ani cross-sectional area as a function of prolapse and muscle defect status...
  58. doi request reprint Surgical approaches to postobstetrical perineal body defects (rectovaginal fistula and chronic third and fourth-degree lacerations)
    John O L Delancey
    Department Obstetrics and Gynecology, University of Michigan, Women s Hospital, Ann Arbor, Michigan, USA
    Clin Obstet Gynecol 53:134-44. 2010
    ..Key concepts include a tension-free repair, meticulous hemostasis, and postoperative bowel management...
  59. pmc Vaginal thickness, cross-sectional area, and perimeter in women with and those without prolapse
    Yvonne Hsu
    Division of Gynecology, Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, Michigan, USA
    Obstet Gynecol 105:1012-7. 2005
    ..Use axial magnetic resonance imaging to test the null hypothesis that no difference exists in apparent vaginal thickness between women with and those without prolapse...
  60. doi request reprint Symptom resolution after operative management of complications from transvaginal mesh
    Erin C Crosby
    Departments of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan, and Northwestern University Feinberg School of Medicine, Chicago, Illinois
    Obstet Gynecol 123:134-9. 2014
    ..Complications from transvaginal mesh placed for prolapse often require operative management. The aim of this study is to describe the outcomes of vaginal mesh removal...
  61. doi request reprint Evidence of perineural invasion on prostate biopsy specimen and survival after radical prostatectomy
    John O Delancey
    University of Michigan Medical School, University of Michigan, Ann Arbor, MI, USA
    Urology 81:354-7. 2013
    ....
  62. pmc Racial differences in self-reported healthcare seeking and treatment for urinary incontinence in community-dwelling women from the EPI Study
    Mitchell B Berger
    Department of Obstetrics and Gynecology, School of Nursing, University of Michigan, Ann Arbor, Michigan, USA
    Neurourol Urodyn 30:1442-7. 2011
    ....
  63. pmc Structural position of the posterior vagina and pelvic floor in women with and without posterior vaginal prolapse
    Christina Lewicky-Gaupp
    Pelvic Floor Research Group, Division of Gynecology, Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, MI, USA
    Am J Obstet Gynecol 202:497.e1-6. 2010
    ..The objective of the study was to compare pelvic structure location on magnetic resonance imaging (MRI) during maximal Valsalva among women with posterior prolapse and those with normal support...
  64. pmc The axial location of structural regions in the urethra: a magnetic resonance study in nulliparous women
    Wolfgang H Umek
    Division of Gynecology, Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, Michigan 48109 0276, USA
    Obstet Gynecol 102:1039-45. 2003
    ..To define and quantify the appearance and location of distinct regions of the bladder neck and urethra by using axial magnetic resonance images from healthy, continent, nulliparous women...
  65. ncbi request reprint A technique to evaluate the thickness and density of nonvascular smooth muscle in the suburethral fibromuscular layer
    Daniel M Morgan
    University of Michigan Medical Center, 1500 E Medical Center Drive, Room L4100, Ann Arbor, MI 48109 0276, USA
    Am J Obstet Gynecol 188:1183-5. 2003
    ..This study was undertaken to develop a method to systematically quantify differences in the thickness and density of nonvascular smooth muscle within the SUFML and to demonstrate its use in assessing variation...
  66. pmc Racial differences in bother for women with urinary incontinence in the Establishing the Prevalence of Incontinence (EPI) study
    Christina Lewicky-Gaupp
    Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, MI, USA
    Am J Obstet Gynecol 201:510.e1-6. 2009
    ..The purpose of this study was to compare differences in degree of bother in black and white women with urinary incontinence (UI)...
  67. pmc Interrater reliability and physical examination of the pubovisceral portion of the levator ani muscle, validity comparisons using MR imaging
    Rohna Kearney
    Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, Michigan, USA
    Neurourol Urodyn 25:50-4. 2006
    ..This study aims to determine interrater reliability of physical examination in detecting these defects, and to validate findings from physical examination using comparisons with MR images...
  68. ncbi request reprint Sexual function, quality of life, and severity of anal incontinence after anal sphincteroplasty
    Elisa R Trowbridge
    Department of Obstetrics and Gynecology, Division of Gynecology, University of Michigan Medical School, Ann Arbor, MI, USA
    Am J Obstet Gynecol 195:1753-7. 2006
    ..The purpose of this study was to determine the severity of anal incontinence and its impact on quality of life and sexual function in women after anal sphincteroplasty...
  69. doi request reprint Complications requiring reoperation following vaginal mesh kit procedures for prolapse
    Rebecca U Margulies
    Pelvic Floor Research Group and the Department of Obstetrics and Gynecology, University of Michigan School of Medicine, Ann Arbor, MI, USA
    Am J Obstet Gynecol 199:678.e1-4. 2008
    ..The objective of the study was to the characterize the symptoms and management of vaginal mesh-related complications requiring operative intervention...
  70. doi request reprint Are bony pelvis dimensions associated with levator ani defects? A case-control study
    Mitchell B Berger
    Pelvic Floor Research Group, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA
    Int Urogynecol J 24:1377-83. 2013
    ..The goal of this study was to determine whether bony pelvis dimensions are different when comparing women with severe bilateral levator ani defects (LAD) with those with normal muscles...
  71. doi request reprint Pathologic evaluation of explanted vaginal mesh: interdisciplinary experience from a referral center
    Tovia M Smith
    Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, University of Michigan Health System, Ann Arbor, MI, USA
    Female Pelvic Med Reconstr Surg 19:238-41. 2013
    ....
  72. pmc Bony pelvis dimensions in women with and without stress urinary incontinence
    Mitchell B Berger
    Pelvic Floor Research Group, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan, USA
    Neurourol Urodyn 32:37-42. 2013
    ..To test the null hypothesis that bony pelvis dimensions are similar in women with and without stress urinary incontinence (SUI), both in the postpartum and midlife periods...
  73. pmc Incidental bartholin gland cysts identified on pelvic magnetic resonance imaging
    Mitchell B Berger
    Department of Obstetrics and Gynecology and the Pelvic Floor Research Group, University of Michigan Medical School, Ann Arbor, Michigan 48109 5276, USA
    Obstet Gynecol 120:798-802. 2012
    ..The secondary aim was to investigate potential demographic characteristics associated with Bartholin gland cysts...
  74. ncbi request reprint Heterogeneity in anatomic outcome of sacrospinous ligament fixation for prolapse: a systematic review
    Daniel M Morgan
    Departments of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan 48109, USA
    Obstet Gynecol 109:1424-33. 2007
    ..To explore why failure rates vary so much between published reports of sacrospinous ligament fixation to correct pelvic organ prolapse and what the potential sources of heterogeneity may be...
  75. ncbi request reprint Age effects on urethral striated muscle. I. Changes in number and diameter of striated muscle fibers in the ventral urethra
    Daniele Perucchini
    Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, USA
    Am J Obstet Gynecol 186:351-5. 2002
    ..This study was undertaken to test the null hypothesis that the number of striated muscle fibers in the ventral wall of the female urethra remains constant with increasing age...
  76. ncbi request reprint Age effects on urethral striated muscle. II. Anatomic location of muscle loss
    Daniele Perucchini
    Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, USA
    Am J Obstet Gynecol 186:356-60. 2002
    ..The purpose of the study was to measure the thickness and cross-sectional area of urethral muscle layers to identify localized striated muscle loss...
  77. ncbi request reprint Anatomic variations in the levator ani muscle, endopelvic fascia, and urethra in nulliparas evaluated by magnetic resonance imaging
    Ralf Tunn
    Department of Obstetrics and Gynecology, Charite Campus Mitte, Humboldt Universitat zu Berlin, Berlin, Germany
    Am J Obstet Gynecol 188:116-21. 2003
    ..The purpose of this study was to develop a system to quantify interindividual variation in the appearance of continence system structures in normal continent nulliparous women...
  78. pmc The relationship between anterior and apical compartment support
    Aimee Summers
    Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA
    Am J Obstet Gynecol 194:1438-43. 2006
    ....
  79. pmc Pelvic architectural distortion is associated with pelvic organ prolapse
    Markus Huebner
    Pelvic Floor Research Group, University of Michigan, Ann Arbor, MI, USA
    Int Urogynecol J Pelvic Floor Dysfunct 19:863-7. 2008
    ..2 for the presence of architectural distortion (95% CI = 1.1-4.6). Pelvic organ prolapse is associated with the presence of visible architectural distortion on MR scans...
  80. pmc Clitoral anatomy in nulliparous, healthy, premenopausal volunteers using unenhanced magnetic resonance imaging
    Helen E O'Connell
    Department of Surgery, University of Melbourne, Parkville, Victoria, Australia
    J Urol 173:2060-3. 2005
    ..We determined the magnetic resonance imaging (MRI) characteristics of normal clitoral anatomy...
  81. pmc Levator ani muscle stretch induced by simulated vaginal birth
    Kuo Cheng Lien
    Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan, USA
    Obstet Gynecol 103:31-40. 2004
    ..To develop a three-dimensional computer model to predict levator ani muscle stretch during vaginal birth...
  82. pmc Obstetric factors associated with levator ani muscle injury after vaginal birth
    Rohna Kearney
    University College Hospital, London, United Kingdom
    Obstet Gynecol 107:144-9. 2006
    ..To identify obstetric factors associated with development of levator ani injury after vaginal birth...
  83. pmc Prevalence of symptomatic pelvic floor disorders in US women
    Ingrid Nygaard
    Department of Obstetrics and Gynecology, University of Utah School of Medicine, 30 N 1900 E, Salt Lake City, UT 84132 2209, USA
    JAMA 300:1311-6. 2008
    ..No national prevalence estimates derived from the same population-based sample exists for multiple pelvic floor disorders in women in the United States...
  84. pmc Age effects on internal anal sphincter thickness and diameter in nulliparous females
    Markus Huebner
    Pelvic Floor Research Group, University of Michigan, Ann Arbor, MI 48109 0276, USA
    Dis Colon Rectum 50:1405-11. 2007
    ..This study compares the effect of aging on the internal anal sphincter thickness and diameter in younger and older nulliparous females without symptoms of fecal incontinence undisturbed by an endoanal probe...
  85. pmc Establishing the prevalence of incontinence study: racial differences in women's patterns of urinary incontinence
    Dee E Fenner
    Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan, USA
    J Urol 179:1455-60. 2008
    ..We examine racial differences in urinary incontinence prevalence, frequency, quantity, type, and risk factors in a population based sample of community dwelling black and white women...
  86. pmc Origin and insertion points involved in levator ani muscle defects
    Rebecca U Margulies
    Pelvic Floor Research Group, University of Michigan, Ann Arbor, MI, USA
    Am J Obstet Gynecol 196:251.e1-5. 2007
    ..This project sought to identify and to describe the anatomical connections affected by levator ani defects involving the pubovisceral portion of the muscle...
  87. pmc Quantitative analysis of uterosacral ligament origin and insertion points by magnetic resonance imaging
    Wolfgang H Umek
    Division of Gynecology, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA
    Obstet Gynecol 103:447-51. 2004
    ....
  88. ncbi request reprint Unspeakable women's problems and the hidden epidemic of female pelvic floor dysfunction
    John O L Delancey
    University of Michigan Medical School, USA
    J Br Menopause Soc 10:4-6. 2004

Research Grants16

  1. DO WOMEN WITH PROLAPSE HAVE LEVATOR ANI IMPAIRMENT?
    John DeLancey; Fiscal Year: 2004
    ..This information will guide future research as well as helping to devising more rational treatment selection. ..
  2. Mechanisms of anterior vaginal wall support failure
    John DeLancey; Fiscal Year: 2009
    ..These insights are needed to advance disease mechanisms research in order to reduce the 30% recurrence rate with surgery, and develop preventative strategies to lessen the need for surgery in 400,000 women a year. ..
  3. Birth, Muscle Injury and Pelvic Floor Dysfunction
    John DeLancey; Fiscal Year: 2007
    ..This research will produce insights to address the women's health problem of pelvic floor dysfunction ..
  4. Mechanisms of anterior vaginal wall support failure
    John DeLancey; Fiscal Year: 2007
    ..These insights are needed to advance disease mechanisms research in order to reduce the 30% recurrence rate with surgery, and develop preventative strategies to lessen the need for surgery in 400,000 women a year. ..
  5. Race Differences in Female UI: Epidemiology and Biology
    John DeLancey; Fiscal Year: 2005
    ..Knowledge of these factors can then provide the basis for risk factor identification and the development of preventive strategies appropriate to different racial groups. ..
  6. Mechanisms of anterior vaginal wall support failure
    John O L Delancey; Fiscal Year: 2010
    ....