Christopher R DeFilippi

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. ncbi Physical activity, change in biomarkers of myocardial stress and injury, and subsequent heart failure risk in older adults
    Christopher R DeFilippi
    Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21212, USA
    J Am Coll Cardiol 60:2539-47. 2012
  2. ncbi Interpreting cardiac troponin results from high-sensitivity assays in chronic kidney disease without acute coronary syndrome
    Christopher deFilippi
    Division of Cardiology, Department of Medicine, University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21201, USA
    Clin Chem 58:1342-51. 2012
  3. ncbi Left ventricular ejection fraction assessment in older adults: an adjunct to natriuretic peptide testing to identify risk of new-onset heart failure and cardiovascular death?
    Christopher R DeFilippi
    University of Maryland School of Medicine, Baltimore, MD, USA
    J Am Coll Cardiol 58:1497-506. 2011
  4. ncbi Association of serial measures of cardiac troponin T using a sensitive assay with incident heart failure and cardiovascular mortality in older adults
    Christopher R DeFilippi
    Department of Medicine, G3K63, University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21212, USA
    JAMA 304:2494-502. 2010
  5. ncbi Dynamic cardiovascular risk assessment in elderly people. The role of repeated N-terminal pro-B-type natriuretic peptide testing
    Christopher R DeFilippi
    Division of Cardiology, Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Am Coll Cardiol 55:441-50. 2010
  6. ncbi Cardiac troponin T in chest pain unit patients without ischemic electrocardiographic changes: angiographic correlates and long-term clinical outcomes
    C R deFilippi
    Department of Internal Medicine, University of Texas Medical Branch at Galveston, USA
    J Am Coll Cardiol 35:1827-34. 2000
  7. ncbi Frequency and cause of cardiac troponin T elevation in chronic hemodialysis patients from study of cardiovascular magnetic resonance
    Christopher R DeFilippi
    Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA
    Am J Cardiol 100:885-9. 2007
  8. ncbi Impact of renal disease on natriuretic peptide testing for diagnosing decompensated heart failure and predicting mortality
    Christopher R DeFilippi
    Division of Cardiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Clin Chem 53:1511-9. 2007
  9. ncbi Randomized comparison of a strategy of predischarge coronary angiography versus exercise testing in low-risk patients in a chest pain unit: in-hospital and long-term outcomes
    C R deFilippi
    Department of Internal Medicine, University of Texas Medical Branch at Galveston, USA
    J Am Coll Cardiol 37:2042-9. 2001
  10. ncbi N-terminal pro-B-type natriuretic peptide for predicting coronary disease and left ventricular hypertrophy in asymptomatic CKD not requiring dialysis
    Christopher R DeFilippi
    Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA
    Am J Kidney Dis 46:35-44. 2005

Detail Information

Publications24

  1. ncbi Physical activity, change in biomarkers of myocardial stress and injury, and subsequent heart failure risk in older adults
    Christopher R DeFilippi
    Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21212, USA
    J Am Coll Cardiol 60:2539-47. 2012
    ....
  2. ncbi Interpreting cardiac troponin results from high-sensitivity assays in chronic kidney disease without acute coronary syndrome
    Christopher deFilippi
    Division of Cardiology, Department of Medicine, University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21201, USA
    Clin Chem 58:1342-51. 2012
    ..We examined the associations between hs cTnI and cTnT, cardiovascular disease, and renal function in outpatients with stable CKD...
  3. ncbi Left ventricular ejection fraction assessment in older adults: an adjunct to natriuretic peptide testing to identify risk of new-onset heart failure and cardiovascular death?
    Christopher R DeFilippi
    University of Maryland School of Medicine, Baltimore, MD, USA
    J Am Coll Cardiol 58:1497-506. 2011
    ....
  4. ncbi Association of serial measures of cardiac troponin T using a sensitive assay with incident heart failure and cardiovascular mortality in older adults
    Christopher R DeFilippi
    Department of Medicine, G3K63, University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21212, USA
    JAMA 304:2494-502. 2010
    ..Older adults comprise the majority of new-onset heart failure (HF) diagnoses, but traditional risk-factor prediction models have limited accuracy in this population to identify those at highest risk for hospitalization or death...
  5. ncbi Dynamic cardiovascular risk assessment in elderly people. The role of repeated N-terminal pro-B-type natriuretic peptide testing
    Christopher R DeFilippi
    Division of Cardiology, Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Am Coll Cardiol 55:441-50. 2010
    ..This study sought to determine whether serial measurement of N-terminal pro-B-type natriuretic peptide (NT-proBNP) in community-dwelling elderly people would provide additional prognostic information to that from traditional risk factors...
  6. ncbi Cardiac troponin T in chest pain unit patients without ischemic electrocardiographic changes: angiographic correlates and long-term clinical outcomes
    C R deFilippi
    Department of Internal Medicine, University of Texas Medical Branch at Galveston, USA
    J Am Coll Cardiol 35:1827-34. 2000
    ....
  7. ncbi Frequency and cause of cardiac troponin T elevation in chronic hemodialysis patients from study of cardiovascular magnetic resonance
    Christopher R DeFilippi
    Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA
    Am J Cardiol 100:885-9. 2007
    ....
  8. ncbi Impact of renal disease on natriuretic peptide testing for diagnosing decompensated heart failure and predicting mortality
    Christopher R DeFilippi
    Division of Cardiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Clin Chem 53:1511-9. 2007
    ..We compared the accuracy of B-type natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) for diagnosing decompensated HF and predicting mortality across the spectrum of renal function...
  9. ncbi Randomized comparison of a strategy of predischarge coronary angiography versus exercise testing in low-risk patients in a chest pain unit: in-hospital and long-term outcomes
    C R deFilippi
    Department of Internal Medicine, University of Texas Medical Branch at Galveston, USA
    J Am Coll Cardiol 37:2042-9. 2001
    ....
  10. ncbi N-terminal pro-B-type natriuretic peptide for predicting coronary disease and left ventricular hypertrophy in asymptomatic CKD not requiring dialysis
    Christopher R DeFilippi
    Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA
    Am J Kidney Dis 46:35-44. 2005
    ..We sought to determine whether there is an association between NT-proBNP level and coronary artery disease (CAD) and left ventricular hypertrophy (LVH) in this population...
  11. ncbi Cardiac troponin T and C-reactive protein for predicting prognosis, coronary atherosclerosis, and cardiomyopathy in patients undergoing long-term hemodialysis
    Christopher deFilippi
    Department of Medicine, University of Maryland School of Medicine, Baltimore 21201, USA
    JAMA 290:353-9. 2003
    ..However, for patients with end-stage renal disease (ESRD) the ability of combinations of these markers to predict outcomes, and their association with cardiac pathology, are unclear...
  12. ncbi Lack of diagnostic and prognostic utility of circulating plasma myeloperoxidase concentrations in patients presenting with dyspnea
    Keyur B Shah
    The University of Maryland School of Medicine, Department of Medicine, Baltimore, MD, USA
    Clin Chem 55:59-67. 2009
    ..We sought to assess the diagnostic accuracy of MPO for acute decompensated heart failure (ADHF) and its prognostic value for patients with acute dyspnea...
  13. ncbi Prognostic utility of ST2 in patients with acute dyspnea and preserved left ventricular ejection fraction
    Keyur B Shah
    Division of Cardiology, Virginia Commonwealth University, Richmond, VA, USA
    Clin Chem 57:874-82. 2011
    ....
  14. ncbi Cardiac microinjury measured by troponin T predicts collagen metabolism in adults aged >=65 years with heart failure
    Willem J Kop
    Department of Medicine Cardiology, University of Maryland, Baltimore, MD, USA
    Circ Heart Fail 5:406-13. 2012
    ..These findings are important to the biology of myocardial fibrosis and tissue repair. Serial evaluation of cTnT combined with collagen metabolism markers may further elucidate the pathophysiology of heart failure...
  15. ncbi Post-discharge changes in NT-proBNP and quality of life after acute dyspnea hospitalization as predictors of one-year outcomes
    Keyur B Shah
    Virginia Commonwealth University Medical Center, Department of Medicine, Richmond, VA, USA
    Clin Biochem 43:1405-10. 2010
    ..The association of serial NT-proBNP changes and poor quality of life (QOL) with progressive heart failure (HF) and clinical outcomes in emergency department dyspnea patients is poorly understood...
  16. ncbi Natriuretic peptides and echocardiography in acute dyspnoea: implication of elevated levels with normal systolic function
    Keyur B Shah
    Division of Cardiology, Department of Medicine, The University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Eur J Heart Fail 11:659-67. 2009
    ....
  17. ncbi N-terminal pro-B-type natriuretic peptide and B-type natriuretic peptide for identifying coronary artery disease and left ventricular hypertrophy in ambulatory chronic kidney disease patients
    Ijaz A Khan
    Division of Cardiology, University of Maryland School of Medicine, Baltimore, Maryland, USA
    Am J Cardiol 97:1530-4. 2006
    ..80, p = 0.001 for NT-pro-BNP; AUC 0.82, p = 0.0004 for BNP; p = 0.45 for NT-pro-BNP vs BNP). In conclusion, NT-pro-BNP and BNP levels are significant and equivalent indicators of CAD and LVH in asymptomatic patients with CKD...
  18. ncbi Impact of increased body mass index on accuracy of B-type natriuretic peptide (BNP) and N-terminal proBNP for diagnosis of decompensated heart failure and prediction of all-cause mortality
    Robert H Christenson
    Department of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Clin Chem 56:633-41. 2010
    ..Whether increased BMI affects accuracy of these biomarkers for diagnosing decompensated heart failure (HF) and predicting outcomes is unknown...
  19. ncbi Multi-center determination of galectin-3 assay performance characteristics: Anatomy of a novel assay for use in heart failure
    Robert H Christenson
    University of Maryland School of Medicine, Baltimore, MD, USA
    Clin Biochem 43:683-90. 2010
    ..Key analytical performance characteristics, the reference distribution and association of galectin-3 levels with clinical outcome in heart failure patients are defined...
  20. ncbi Adjunctive handgrip during dobutamine stress echocardiography: invasive assessment of myocardial oxygen consumption in humans
    Ijaz A Khan
    Division of Cardiology, University of Maryland School of Medicine, Baltimore, Maryland 21201-1595, USA
    Clin Cardiol 28:349-52. 2005
    ..The MVO2 increased from 29 +/- 8 ml/min at peak DSE to 31 +/- 9 ml/min with adjunctive HG (p = 0.03). CONCLUSION: Handgrip adjunctive to peak DSE results in a modest increase in MVO2, primarily by an increase in end-systolic wall stress...
  21. ncbi Pulmonary hypertension adversely affects short- and long-term survival after mitral valve operation for mitral regurgitation: implications for timing of surgery
    Mehrdad Ghoreishi
    Division of Cardiac Surgery, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    J Thorac Cardiovasc Surg 142:1439-52. 2011
    ..We investigated the impact of preoperative pulmonary hypertension (PH) on early and late outcomes after mitral valve operation for mitral regurgitation...
  22. ncbi Fibroblast growth factor 23 and left ventricular hypertrophy in chronic kidney disease
    ORLANDO M GUTIERREZ
    Division of Nephrology and Hypertension, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    Circulation 119:2545-52. 2009
    ..We conducted a cross-sectional study to test the hypothesis that elevated FGF-23 concentrations are associated with left ventricular hypertrophy and coronary artery calcification in patients with CKD...
  23. ncbi Amino-terminal pro-B-type natriuretic peptide testing in renal disease
    Christopher deFilippi
    Division of Cardiology, University of Maryland, Baltimore, MD, USA
    Am J Cardiol 101:82-8. 2008
    ..Thus, NT-proBNP testing remains useful for the diagnostic and prognostic evaluation of patients with CKD...
  24. ncbi N-terminal pro-B-type natriuretic peptide is a major predictor of the development of atrial fibrillation: the Cardiovascular Health Study
    Kristen K Patton
    Division of Cardiology, University of Washington, Seattle, WA 98115, USA
    Circulation 120:1768-74. 2009
    ..Elevated B-type natriuretic peptide levels have been associated with the risk of heart failure, AF, and mortality...