Research Topics
| M D DeanSummaryAffiliation: University of Arizona Country: USA Publications
Research Grants
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Detail Information
Publications
Proteomics and comparative genomic investigations reveal heterogeneity in evolutionary rate of male reproductive proteins in mice (Mus domesticus)Matthew D Dean
Department of Ecology and Evolutionary Biology, University of Arizona, AZ, USA
Mol Biol Evol 26:1733-43. 2009..In contrast, proteins from the other five tissues showed significantly lower nonsynonymous substitution, revealing a previously unappreciated level of evolutionary constraint acting on the majority of male reproductive proteins...
Faster fertilization rate in conspecific versus heterospecific matings in house miceMatthew D Dean
Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona 85721, USA
Evolution 63:20-8. 2009..We discuss the implications of faster conspecific fertilization in terms of reproductive isolation among these two naturally hybridizing species...
Adaptive evolution of proteins secreted during sperm maturation: an analysis of the mouse epididymal transcriptomeMatthew D Dean
Department of Ecology and Evolutionary Biology, University of Arizona, USA
Mol Biol Evol 25:383-92. 2008..Immunity and protein modification functions were significantly overrepresented among epididymis-specialized, secreted genes. These analyses identified a group of genes likely to be important in male reproductive success...
The frequency of multiple paternity suggests that sperm competition is common in house mice (Mus domesticus)M D Dean
University of Arizona, Ecology and Evolution, 333 Biosciences West, Tucson, AZ 85721, USA
Mol Ecol 15:4141-51. 2006..This study suggests that sperm competition is an important aspect of postcopulatory sexual selection in house mice...
A Wolbachia-associated fitness benefit depends on genetic background in Drosophila simulansMatthew D Dean
University of Iowa, 202 Biology Building, Iowa City, IA 52242, USA
Proc Biol Sci 273:1415-20. 2006..In contrast, wHa did not affect the fitness of siI or siII flies. This study points to the importance of host-by-symbiont interaction terms that may play an important role in organismal-fitness...
High divergence among Drosophila simulans mitochondrial haplogroups arose in midst of long term purifying selectionMatthew D Dean
University of Iowa, 208 Biology Building, Iowa City, IA 52242, USA
Mol Phylogenet Evol 36:328-37. 2005..simulans haplogroups have persisted in isolation, perhaps due to association with the bacterial symbiont Wolbachia and/or demographic history, introducing a bias against the fixation of slightly deleterious mutations...
Dynamics of double and single Wolbachia infections in Drosophila simulans from New CaledoniaA C James
Department of Biology, University of Iowa, Iowa City, IA 52242, USA
Heredity (Edinb) 88:182-9. 2002..Finally, we discuss the nomenclature of Wolbachia strain designation...
Influence of two Wolbachia strains on population structure of East African Drosophila simulansMatthew D Dean
Department of Biological Sciences, University of Iowa, Iowa City, Iowa 52242-1324, USA
Genetics 165:1959-69. 2003..These populations offer a unique opportunity to monitor evolutionary dynamics in ancestral populations that harbor multiple strains of Wolbachia...
A complex genetic basis to X-linked hybrid male sterility between two species of house miceJeffrey M Good
Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona 85721, USA
Genetics 179:2213-28. 2008..musculus X chromosome involved in hybrid male sterility. Only a handful of spermatogenic genes are within this region, including one of the most rapidly evolving genes on the mouse X chromosome...
The mitochondrial genome: mutation, selection and recombinationJ W Ballard
Department of Biological Sciences University of Iowa, Iowa City, Iowa 52242, USA
Curr Opin Genet Dev 11:667-72. 2001..Experimentally disrupting naturally occurring combinations of nuclear and mitochondrial genomes should provide insights into the coevolutionary dynamics among genomes...
Linking phylogenetics with population genetics to reconstruct the geographic origin of a speciesMatthew D Dean
University of Iowa, 202 Biology Building, Iowa City, IA 52242, USA
Mol Phylogenet Evol 32:998-1009. 2004..We find that the Madagascar population has elevated genetic polymorphism relative to non-Madagascar sequences. These data are corroborated by mitochondrial DNA sequence data...
Linkage disequilibrium in wild miceCathy C Laurie
Department of Biostatistics, University of Washington, Seattle, Washington, United States of America
PLoS Genet 3:e144. 2007....
Research Grants
- EVOLUTIONARY GENETICS OF MALE REPRODUCTIVE TRAITS IN MUSMATTHEW DEAN; Fiscal Year: 2006..These studies will help uncover the genetic basis of male reproductive fitness in a natural population of house mice. ..
