Camin Dean

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. ncbi request reprint Neuroligins and neurexins: linking cell adhesion, synapse formation and cognitive function
    Camin Dean
    Department of Physiology, University of Wisconsin Medical School, Madison, WI 53706, USA
    Trends Neurosci 29:21-9. 2006
  2. pmc Neurexin mediates the assembly of presynaptic terminals
    Camin Dean
    Department of Molecular and Cell Biology, University of California, Berkeley, 271 LSA, California 94720, USA
    Nat Neurosci 6:708-16. 2003
  3. pmc Axonal and dendritic synaptotagmin isoforms revealed by a pHluorin-syt functional screen
    Camin Dean
    Department of Neuroscience, Howard Hughes Medical Institute, University of Wisconsin, Madison, WI 53706, USA
    Mol Biol Cell 23:1715-27. 2012
  4. pmc Distinct subsets of Syt-IV/BDNF vesicles are sorted to axons versus dendrites and recruited to synapses by activity
    Camin Dean
    Department of Neuroscience, University of Wisconsin, Madison, Wisconsin 53706, USA
    J Neurosci 32:5398-413. 2012
  5. pmc Synaptotagmin IV: a multifunctional regulator of peptidergic nerve terminals
    Zhenjie Zhang
    Department of Physiology, University of Wisconsin School of Medicine and Public Health, 1300 University Avenue, Madison, Wisconsin 53706, USA
    Nat Neurosci 12:163-71. 2009
  6. pmc Autapses and networks of hippocampal neurons exhibit distinct synaptic transmission phenotypes in the absence of synaptotagmin I
    Huisheng Liu
    Howard Hughes Medical Institute and Department of Physiology, University of Wisconsin, Madison, Wisconsin 53706, USA
    J Neurosci 29:7395-403. 2009
  7. pmc Synaptotagmin-IV modulates synaptic function and long-term potentiation by regulating BDNF release
    Camin Dean
    Department of Physiology, University of Wisconsin, Madison, Wisconsin, USA
    Nat Neurosci 12:767-76. 2009
  8. pmc "Self" versus "non-self" connectivity dictates properties of synaptic transmission and plasticity
    Huisheng Liu
    Department of Neuroscience and Howard Hughes Medical Institute, University of Wisconsin, Madison, Wisconsin, USA
    PLoS ONE 8:e62414. 2013
  9. ncbi request reprint SV2 is the protein receptor for botulinum neurotoxin A
    Min Dong
    Howard Hughes Medical Institute and Department of Physiology, University of Wisconsin, Madison, WI 53706, USA
    Science 312:592-6. 2006
  10. pmc Neuronal activation by GPI-linked neuroligin-1 displayed in synthetic lipid bilayer membranes
    Michael M Baksh
    Department of Chemistry, University of California Berkeley, 94720, USA
    Langmuir 21:10693-8. 2005

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Neuroligins and neurexins: linking cell adhesion, synapse formation and cognitive function
    Camin Dean
    Department of Physiology, University of Wisconsin Medical School, Madison, WI 53706, USA
    Trends Neurosci 29:21-9. 2006
    ..Here, we review several recent studies that offer clues as to how these proteins form synapses and how they might function in the brain to establish and modify neuronal network properties and cognition...
  2. pmc Neurexin mediates the assembly of presynaptic terminals
    Camin Dean
    Department of Molecular and Cell Biology, University of California, Berkeley, 271 LSA, California 94720, USA
    Nat Neurosci 6:708-16. 2003
    ..In response to this clustering, neurexins nucleate the assembly of a cytoplasmic scaffold to which the exocytotic apparatus is recruited...
  3. pmc Axonal and dendritic synaptotagmin isoforms revealed by a pHluorin-syt functional screen
    Camin Dean
    Department of Neuroscience, Howard Hughes Medical Institute, University of Wisconsin, Madison, WI 53706, USA
    Mol Biol Cell 23:1715-27. 2012
    ..Hence most syt isoforms localize to distinct secretory organelles in both axons and dendrites and may regulate neuropeptide/neurotrophin release to modulate neuronal function...
  4. pmc Distinct subsets of Syt-IV/BDNF vesicles are sorted to axons versus dendrites and recruited to synapses by activity
    Camin Dean
    Department of Neuroscience, University of Wisconsin, Madison, Wisconsin 53706, USA
    J Neurosci 32:5398-413. 2012
    ..These findings demonstrate that BDNF-containing vesicles can be targeted to specific sites in neurons and suggest that syt-IV-regulated BDNF secretion is subject to spatial control to regulate synaptic function in a site-specific manner...
  5. pmc Synaptotagmin IV: a multifunctional regulator of peptidergic nerve terminals
    Zhenjie Zhang
    Department of Physiology, University of Wisconsin School of Medicine and Public Health, 1300 University Avenue, Madison, Wisconsin 53706, USA
    Nat Neurosci 12:163-71. 2009
    ..Given the neuroendocrine functions of the posterior pituitary, changes in Syt IV levels could be involved in endocrine transitions involving alterations in the release of the neuropeptides oxytocin and vasopressin...
  6. pmc Autapses and networks of hippocampal neurons exhibit distinct synaptic transmission phenotypes in the absence of synaptotagmin I
    Huisheng Liu
    Howard Hughes Medical Institute and Department of Physiology, University of Wisconsin, Madison, Wisconsin 53706, USA
    J Neurosci 29:7395-403. 2009
    ..Thus, aspects of synaptic transmission differ between autaptic and dissociated cultures, and the synaptic transmission phenotype, resulting from loss of syt-I, is dictated by the connectivity of neurons...
  7. pmc Synaptotagmin-IV modulates synaptic function and long-term potentiation by regulating BDNF release
    Camin Dean
    Department of Physiology, University of Wisconsin, Madison, Wisconsin, USA
    Nat Neurosci 12:767-76. 2009
    ..Thus, regulation of BDNF secretion by syt-IV emerges as a mechanism for maintaining synaptic strength in a useful range during LTP...
  8. pmc "Self" versus "non-self" connectivity dictates properties of synaptic transmission and plasticity
    Huisheng Liu
    Department of Neuroscience and Howard Hughes Medical Institute, University of Wisconsin, Madison, Wisconsin, USA
    PLoS ONE 8:e62414. 2013
    ..Thus neurons can distinguish whether they are connected via "self" or "non-self" synapses and have the ability to adjust their plasticity parameters when connected to other neurons...
  9. ncbi request reprint SV2 is the protein receptor for botulinum neurotoxin A
    Min Dong
    Howard Hughes Medical Institute and Department of Physiology, University of Wisconsin, Madison, WI 53706, USA
    Science 312:592-6. 2006
    ..Finally, mice that lacked an SV2 isoform (SV2B) displayed reduced sensitivity to BoNT/A. Thus, SV2 acts as the protein receptor for BoNT/A...
  10. pmc Neuronal activation by GPI-linked neuroligin-1 displayed in synthetic lipid bilayer membranes
    Michael M Baksh
    Department of Chemistry, University of California Berkeley, 94720, USA
    Langmuir 21:10693-8. 2005
    ..In addition, the synthetic membrane environment affords control over both lipid and protein composition. This technology is easily implemented and can be applied to a wide variety of cellular studies...