David Deamer

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint A giant step towards artificial life?
    David Deamer
    Department of Biomolecular Engineering, University of California, Santa Cruz, CA 95064, USA
    Trends Biotechnol 23:336-8. 2005
  2. ncbi request reprint The first cell membranes
    David Deamer
    Department of Chemistry and Biochemistry, University of California at Santa Cruz, Santa Cruz, California 95064, USA
    Astrobiology 2:371-81. 2002
  3. pmc Discrimination among individual Watson-Crick base pairs at the termini of single DNA hairpin molecules
    Wenonah A Vercoutere
    Center for Biomolecular Science and Engineering, Department of Chemistry and Biochemistry, and Howard Hughes Medical Institute, University of California, Santa Cruz, CA 95064, USA
    Nucleic Acids Res 31:1311-8. 2003
  4. pmc Highly accurate classification of Watson-Crick basepairs on termini of single DNA molecules
    Stephen Winters-Hilt
    Center for Biomolecular Science and Engineering, University of California, Santa Cruz, California 95064, USA
    Biophys J 84:967-76. 2003
  5. pmc Bioenergetics and life's origins
    David Deamer
    Department of Biomolecular Engineering, Baskin School of Engineering, University of California, Santa Cruz, California 95064, USA
    Cold Spring Harb Perspect Biol 2:a004929. 2010
  6. pmc Self-assembly processes in the prebiotic environment
    David Deamer
    Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA 95064, USA
    Philos Trans R Soc Lond B Biol Sci 361:1809-18. 2006
  7. doi request reprint Nanopore analysis of nucleic acids bound to exonucleases and polymerases
    David Deamer
    Department of Biomolecular Engineering, University of California, Santa Cruz, California 95064, USA
    Annu Rev Biophys 39:79-90. 2010
  8. ncbi request reprint Lipid-assisted synthesis of RNA-like polymers from mononucleotides
    Sudha Rajamani
    Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA 95064, USA
    Orig Life Evol Biosph 38:57-74. 2008
  9. ncbi request reprint Evolution. Transitions from nonliving to living matter
    Steen Rasmussen
    Los Alamos National Laboratory, Los Alamos, NM 87545, USA
    Science 303:963-5. 2004
  10. ncbi request reprint The NASA Astrobiology Roadmap
    David J Des Marais
    Space Science Division, NASA Ames Research Center, Moffett Field, California 94035, USA
    Astrobiology 3:219-35. 2003

Collaborators

Detail Information

Publications10

  1. ncbi request reprint A giant step towards artificial life?
    David Deamer
    Department of Biomolecular Engineering, University of California, Santa Cruz, CA 95064, USA
    Trends Biotechnol 23:336-8. 2005
    ..Can we now assemble a living cell? Not quite yet because no one has produced a polymerase that can be reproduced along with growth of the other molecular components required by life. But we are closer than ever before...
  2. ncbi request reprint The first cell membranes
    David Deamer
    Department of Chemistry and Biochemistry, University of California at Santa Cruz, Santa Cruz, California 95064, USA
    Astrobiology 2:371-81. 2002
    ..The goal of future investigations will be to fabricate artificial cells as models of the origin of life...
  3. pmc Discrimination among individual Watson-Crick base pairs at the termini of single DNA hairpin molecules
    Wenonah A Vercoutere
    Center for Biomolecular Science and Engineering, Department of Chemistry and Biochemistry, and Howard Hughes Medical Institute, University of California, Santa Cruz, CA 95064, USA
    Nucleic Acids Res 31:1311-8. 2003
    ..This report constitutes evidence that single Watson-Crick base pairs can be identified within individual unmodified DNA hairpin molecules based on their dynamic behavior in a nanoscale pore...
  4. pmc Highly accurate classification of Watson-Crick basepairs on termini of single DNA molecules
    Stephen Winters-Hilt
    Center for Biomolecular Science and Engineering, University of California, Santa Cruz, California 95064, USA
    Biophys J 84:967-76. 2003
    ..The tuning on HMMs and SVMs enabled biophysical analysis of the captured molecule states and state transitions; structure revealed in the biophysical analysis was used for better feature selection...
  5. pmc Bioenergetics and life's origins
    David Deamer
    Department of Biomolecular Engineering, Baskin School of Engineering, University of California, Santa Cruz, California 95064, USA
    Cold Spring Harb Perspect Biol 2:a004929. 2010
    ..This article examines potential sources of energy available to protocells, and mechanisms by which the energy could be used to drive polymer synthesis...
  6. pmc Self-assembly processes in the prebiotic environment
    David Deamer
    Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA 95064, USA
    Philos Trans R Soc Lond B Biol Sci 361:1809-18. 2006
    ....
  7. doi request reprint Nanopore analysis of nucleic acids bound to exonucleases and polymerases
    David Deamer
    Department of Biomolecular Engineering, University of California, Santa Cruz, California 95064, USA
    Annu Rev Biophys 39:79-90. 2010
    ..The combined enzymatic and voltage control of a DNA molecule in the nanopore can be used to sequence the DNA...
  8. ncbi request reprint Lipid-assisted synthesis of RNA-like polymers from mononucleotides
    Sudha Rajamani
    Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA 95064, USA
    Orig Life Evol Biosph 38:57-74. 2008
    ..In the final hydration step, the RNA-like polymer is encapsulated within lipid vesicles. This process provides a laboratory model of an early stage of evolution toward an RNA World...
  9. ncbi request reprint Evolution. Transitions from nonliving to living matter
    Steen Rasmussen
    Los Alamos National Laboratory, Los Alamos, NM 87545, USA
    Science 303:963-5. 2004
  10. ncbi request reprint The NASA Astrobiology Roadmap
    David J Des Marais
    Space Science Division, NASA Ames Research Center, Moffett Field, California 94035, USA
    Astrobiology 3:219-35. 2003
    ..For each of these goals, Science Objectives outline more specific high-priority efforts for the next 3-5 years. These 18 objectives are being integrated with NASA strategic planning...