Maria De Luca

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. pmc Association of a common LAMA5 variant with anthropometric and metabolic traits in an Italian cohort of healthy elderly subjects
    Maria De Luca
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Exp Gerontol 46:60-4. 2011
  2. ncbi request reprint Mapping quantitative trait loci affecting variation in Drosophila triacylglycerol storage
    Maria De Luca
    Department of Environmental Health Sciences, University of Alabama, Birmingham, AL 35294, USA
    Obes Res 13:1596-605. 2005
  3. pmc A conserved role for syndecan family members in the regulation of whole-body energy metabolism
    Maria De Luca
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
    PLoS ONE 5:e11286. 2010
  4. pmc Genetic variation in a member of the laminin gene family affects variation in body composition in Drosophila and humans
    Maria De Luca
    Department of Nutrition Sciences, School of Health Professions, University of Alabama at Birmingham, 3rd Avenue South, Birmingham, AL 35294 3360, USA
    BMC Genet 9:52. 2008
  5. pmc Nuclear genomic control of naturally occurring variation in mitochondrial function in Drosophila melanogaster
    Patricia Jumbo-Lucioni
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    BMC Genomics 13:659. 2012
  6. pmc Systems genetics analysis of body weight and energy metabolism traits in Drosophila melanogaster
    Patricia Jumbo-Lucioni
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294 3360, USA
    BMC Genomics 11:297. 2010
  7. ncbi request reprint Mapping genetic polymorphisms affecting natural variation in Drosophila longevity
    Maria De Luca
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL, USA
    Methods Mol Biol 371:307-20. 2007
  8. ncbi request reprint Polymorphism in the transcription factor 7-like 2 (TCF7L2) gene is associated with reduced insulin secretion in nondiabetic women
    Julian Munoz
    Department of Nutrition Sciences, 1675 Webb Nutrition Sciences Building, Room 241, University of Alabama, Birmingham, AL 35294, USA
    Diabetes 55:3630-4. 2006
  9. ncbi request reprint Methods for nutrigenomics and longevity studies in Drosophila: effects of diets high in sucrose, palmitic acid, soy, or beef
    Jiatao Ye
    Department of Environmental Health Sciences, University of Alabama at Birmingham, Birmingham, AL, USA
    Methods Mol Biol 371:111-41. 2007
  10. ncbi request reprint Drosophila nutrigenomics can provide clues to human gene-nutrient interactions
    Douglas M Ruden
    Department of Environmental Health Sciences, University of Alabama at Birmingham, Alabama 35294, USA
    Annu Rev Nutr 25:499-522. 2005

Detail Information

Publications12

  1. pmc Association of a common LAMA5 variant with anthropometric and metabolic traits in an Italian cohort of healthy elderly subjects
    Maria De Luca
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Exp Gerontol 46:60-4. 2011
    ..Future studies are warranted to replicate these findings in independent and larger populations and to investigate whether rs659822 is the causal variant responsible for the observed associations...
  2. ncbi request reprint Mapping quantitative trait loci affecting variation in Drosophila triacylglycerol storage
    Maria De Luca
    Department of Environmental Health Sciences, University of Alabama, Birmingham, AL 35294, USA
    Obes Res 13:1596-605. 2005
    ..The objective of our study was to identify quantitative trait loci (QTLs) that contribute to variation in triacylglycerol (TAG) storage in two D. melanogaster laboratory strains...
  3. pmc A conserved role for syndecan family members in the regulation of whole-body energy metabolism
    Maria De Luca
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
    PLoS ONE 5:e11286. 2010
    ..035) and intra-abdominal fat (P = 0.049), and SNP rs2267871 with insulin sensitivity (P = 0.037). Collectively, our results in Drosophila and humans argue that syndecan family members play a key role in the regulation of body metabolism...
  4. pmc Genetic variation in a member of the laminin gene family affects variation in body composition in Drosophila and humans
    Maria De Luca
    Department of Nutrition Sciences, School of Health Professions, University of Alabama at Birmingham, 3rd Avenue South, Birmingham, AL 35294 3360, USA
    BMC Genet 9:52. 2008
    ..Based on our results from Drosophila, we performed a human population-based association study to investigate the effect of natural variation in LAMA5 gene on body composition in humans...
  5. pmc Nuclear genomic control of naturally occurring variation in mitochondrial function in Drosophila melanogaster
    Patricia Jumbo-Lucioni
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    BMC Genomics 13:659. 2012
    ..Here, we used Drosophila melanogaster as our model organism to address this question...
  6. pmc Systems genetics analysis of body weight and energy metabolism traits in Drosophila melanogaster
    Patricia Jumbo-Lucioni
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294 3360, USA
    BMC Genomics 11:297. 2010
    ....
  7. ncbi request reprint Mapping genetic polymorphisms affecting natural variation in Drosophila longevity
    Maria De Luca
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL, USA
    Methods Mol Biol 371:307-20. 2007
    ..This chapter reports details of quantitative complementation tests and linkage disequilibrium mapping to identify positional genes and causative genetic polymorphisms determining variation in Drosophila longevity...
  8. ncbi request reprint Polymorphism in the transcription factor 7-like 2 (TCF7L2) gene is associated with reduced insulin secretion in nondiabetic women
    Julian Munoz
    Department of Nutrition Sciences, 1675 Webb Nutrition Sciences Building, Room 241, University of Alabama, Birmingham, AL 35294, USA
    Diabetes 55:3630-4. 2006
    ..Our data suggest that the TCF7L2 gene is an important factor regulating insulin secretion, which could explain its association with type 2 diabetes...
  9. ncbi request reprint Methods for nutrigenomics and longevity studies in Drosophila: effects of diets high in sucrose, palmitic acid, soy, or beef
    Jiatao Ye
    Department of Environmental Health Sciences, University of Alabama at Birmingham, Birmingham, AL, USA
    Methods Mol Biol 371:111-41. 2007
    ..The significance of these results and other types of nutrigenomics and longevity analyses is discussed...
  10. ncbi request reprint Drosophila nutrigenomics can provide clues to human gene-nutrient interactions
    Douglas M Ruden
    Department of Environmental Health Sciences, University of Alabama at Birmingham, Alabama 35294, USA
    Annu Rev Nutr 25:499-522. 2005
    ..This review summarizes what has already been learned in Drosophila nutrigenomics (with an emphasis on lipids and sterols), critically evaluates the data, and discusses fruitful areas for future research...
  11. ncbi request reprint Dopa decarboxylase (Ddc) affects variation in Drosophila longevity
    Maria De Luca
    Department of Genetics, Box 7614, North Carolina State University, Raleigh, North Carolina 27695, USA
    Nat Genet 34:429-33. 2003
    ..DDC catalyzes the final step in the synthesis of the neurotransmitters, dopamine and serotonin. Thus, these data implicate variation in the synthesis of bioamines as a factor contributing to natural variation in individual life span...
  12. ncbi request reprint A functional interplay between Aurora-A, Plk1 and TPX2 at spindle poles: Plk1 controls centrosomal localization of Aurora-A and TPX2 spindle association
    Maria De Luca
    Institute of Molecular Biology and Pathology, CNR, University of Rome La Sapienza, Rome, Italy
    Cell Cycle 5:296-303. 2006
    ..Based on these results therefore a hierarchical functional relation between Plk1 and the Aurora-A/TPX2 pathway emerges...

Research Grants6

  1. QTL mapping age-related changes in lipid storage
    Maria De Luca; Fiscal Year: 2004
    ..Moreover, knowledge of the nature and frequency of causative genetic polymorphisms will lead to a better understanding of the mechanisms that maintain genetic variation in these traits in natural populations. ..
  2. QTL mapping age-related changes in lipid storage
    Maria De Luca; Fiscal Year: 2005
    ..Moreover, knowledge of the nature and frequency of causative genetic polymorphisms will lead to a better understanding of the mechanisms that maintain genetic variation in these traits in natural populations. ..
  3. QTL mapping age-related changes in lipid storage
    Maria De Luca; Fiscal Year: 2006
    ..Moreover, knowledge of the nature and frequency of causative genetic polymorphisms will lead to a better understanding of the mechanisms that maintain genetic variation in these traits in natural populations. ..
  4. QTL mapping age-related changes in lipid storage
    Maria De Luca; Fiscal Year: 2007
    ..Moreover, knowledge of the nature and frequency of causative genetic polymorphisms will lead to a better understanding of the mechanisms that maintain genetic variation in these traits in natural populations. ..
  5. QTL mapping age-related changes in lipid storage
    Maria De Luca; Fiscal Year: 2007
    ..Moreover, knowledge of the nature and frequency of causative genetic polymorphisms will lead to a better understanding of the mechanisms that maintain genetic variation in these trait in natural populations. ..
  6. Genetic control of quantitative traits associated with the metabolic syndrome
    Maria De Luca; Fiscal Year: 2010
    ..Using this information, human population-based association studies will be performed to investigate the effect of natural variation in the identified regulatory genes on quantitative traits associated with the metabolic syndrome. ..