J C de La Torre

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Critical threshold cerebral hypoperfusion causes Alzheimer's disease?
    J C de La Torre
    Department of Neurosciences, UCSD School of Medicine, La Jolla, CA 92093, USA
    Acta Neuropathol 98:1-8. 1999
  2. ncbi request reprint Critically attained threshold of cerebral hypoperfusion: can it cause Alzheimer's disease?
    J C de La Torre
    Department of Neurosciences, University of California, San Diego, La Jolla 92093, USA
    Ann N Y Acad Sci 903:424-36. 2000
  3. ncbi request reprint Critically attained threshold of cerebral hypoperfusion: the CATCH hypothesis of Alzheimer's pathogenesis
    J C de La Torre
    Department of Neurosciences MTF 0624, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0624, USA
    Neurobiol Aging 21:331-42. 2000
  4. ncbi request reprint Evidence that Alzheimer's disease is a microvascular disorder: the role of constitutive nitric oxide
    J C de La Torre
    Department of Pathology, University of California, San Diego, 1363 Shinly, Suite 100, Escondido, CA 92026, USA
    Brain Res Brain Res Rev 34:119-36. 2000
  5. ncbi request reprint Viral persistence in neurons alters synaptic plasticity and cognitive functions without destruction of brain cells
    J C de La Torre
    Department of Neuropharmacology, Scripps Research Institute, La Jolla, California 92037, USA
    Virology 220:508-15. 1996
  6. ncbi request reprint Impaired cerebromicrovascular perfusion. Summary of evidence in support of its causality in Alzheimer's disease
    J C de La Torre
    Department of Neuroscience, University of California, San Diego, La Jolla, California 92093, USA
    Ann N Y Acad Sci 924:136-52. 2000
  7. ncbi request reprint Hippocampal nitric oxide upregulation precedes memory loss and A beta 1-40 accumulation after chronic brain hypoperfusion in rats
    J C de La Torre
    Department of Pathology, University of California, San Diego, CA
    Neurol Res 25:635-41. 2003
  8. pmc Human plasmacytoid dendritic cells sense lymphocytic choriomeningitis virus-infected cells in vitro
    S F Wieland
    Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, USA
    J Virol 88:752-7. 2014
  9. ncbi request reprint Detection of borna disease virus antigen and RNA in human autopsy brain samples from neuropsychiatric patients
    J C de La Torre
    Department of Neuropharmacology, Scripps Research Institute, La Jolla, California 92037, USA
    Virology 223:272-82. 1996

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Critical threshold cerebral hypoperfusion causes Alzheimer's disease?
    J C de La Torre
    Department of Neurosciences, UCSD School of Medicine, La Jolla, CA 92093, USA
    Acta Neuropathol 98:1-8. 1999
    ..A discussion of target therapy based on the proposed pathogenesis of AD is also briefly reviewed...
  2. ncbi request reprint Critically attained threshold of cerebral hypoperfusion: can it cause Alzheimer's disease?
    J C de La Torre
    Department of Neurosciences, University of California, San Diego, La Jolla 92093, USA
    Ann N Y Acad Sci 903:424-36. 2000
    ....
  3. ncbi request reprint Critically attained threshold of cerebral hypoperfusion: the CATCH hypothesis of Alzheimer's pathogenesis
    J C de La Torre
    Department of Neurosciences MTF 0624, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0624, USA
    Neurobiol Aging 21:331-42. 2000
    ..The possible role of CATCH in familial and early onset Alzheimer's disease is briefly discussed from a theoretical vantagepoint. The growing and most recent evidence in support of the CATCH concept is the focus of this review...
  4. ncbi request reprint Evidence that Alzheimer's disease is a microvascular disorder: the role of constitutive nitric oxide
    J C de La Torre
    Department of Pathology, University of California, San Diego, 1363 Shinly, Suite 100, Escondido, CA 92026, USA
    Brain Res Brain Res Rev 34:119-36. 2000
    ....
  5. ncbi request reprint Viral persistence in neurons alters synaptic plasticity and cognitive functions without destruction of brain cells
    J C de La Torre
    Department of Neuropharmacology, Scripps Research Institute, La Jolla, California 92037, USA
    Virology 220:508-15. 1996
    ..Concurrently, the ability to learn tasks was significantly impaired in these persistently infected mice. Yet, infected neurons remained free from structural injury...
  6. ncbi request reprint Impaired cerebromicrovascular perfusion. Summary of evidence in support of its causality in Alzheimer's disease
    J C de La Torre
    Department of Neuroscience, University of California, San Diego, La Jolla, California 92093, USA
    Ann N Y Acad Sci 924:136-52. 2000
    ..A brief discussion of target therapy based on the proposed pathogenesis of AD is also reviewed...
  7. ncbi request reprint Hippocampal nitric oxide upregulation precedes memory loss and A beta 1-40 accumulation after chronic brain hypoperfusion in rats
    J C de La Torre
    Department of Pathology, University of California, San Diego, CA
    Neurol Res 25:635-41. 2003
    ..These preliminary findings may be important in understanding, at least in part, the molecular mechanisms that precede memory impairment during chronic brain ischemia and as such, the pre-clinical stage leading to Alzheimer's disease...
  8. pmc Human plasmacytoid dendritic cells sense lymphocytic choriomeningitis virus-infected cells in vitro
    S F Wieland
    Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, USA
    J Virol 88:752-7. 2014
    ....
  9. ncbi request reprint Detection of borna disease virus antigen and RNA in human autopsy brain samples from neuropsychiatric patients
    J C de La Torre
    Department of Neuropharmacology, Scripps Research Institute, La Jolla, California 92037, USA
    Virology 223:272-82. 1996
    ..This is the first demonstration that BDV can infect human brain tissue, possibly contributing to the pathophysiology of specific human neuropsychiatric disorders...