Research Topics
Species | M R DawsSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Cloning and characterization of a novel mouse myeloid DAP12-associated receptor familyM R Daws
Department of Immunology, VA Medical Center San Francisco, San Francisco, USA
Eur J Immunol 31:783-91. 2001..Our studies define TREM-2 as a receptor family in mouse macrophages and demonstrate the capacity of these receptors to activate macrophage function through DAP12...
Pattern recognition by TREM-2: binding of anionic ligandsMichael R Daws
Department of Immunology and Division of Infectious Diseases, Veterans Affairs Medical Center and University of California, San Francisco, CA 94121, USA
J Immunol 171:594-9. 2003....
Physiologic functions of activating natural killer (NK) complex-encoded receptors on NK cellsJ C Ryan
Department of Medicine, Veterans Administration Medical Center and University of California, San Francisco 94121, USA
Immunol Rev 181:126-37. 2001..In this review, we will present a detailed analysis of the data supporting this hypothesis with particular relevance toward physiologic NK-cell functions...
Immune rejection of a large sarcoma following cyclophosphamide and IL-12 treatment requires both NK and NK T cells and is associated with the induction of a novel NK T cell populationC Karnbach
Department of Medicine, University of California, San Francisco, CA 94143, USA
J Immunol 167:2569-76. 2001....
Characterization of TREM-3, an activating receptor on mouse macrophages: definition of a family of single Ig domain receptors on mouse chromosome 17Dong Hui Chung
Department of Immunology, VA Medical Center and University of California San Francisco, San Francisco, USA
Eur J Immunol 32:59-66. 2002..Thus, TREM-3 is a novel member of a family of immunoglobulin receptors that form an innate immune gene complex on chromosome 17...
CMRF-35-like molecule-1, a novel mouse myeloid receptor, can inhibit osteoclast formationDong Hui Chung
Veterans Administration Medical Center and University of California, San Francisco, CA 94121, USA
J Immunol 171:6541-8. 2003..Thus, we define a new family of myeloid receptors, and demonstrate that the first member of this family, CLM-1, is an inhibitory receptor, able to block osteoclastogenesis...
The signaling adapter protein DAP12 regulates multinucleation during osteoclast developmentMary Beth Humphrey
Department of Medicine, VA Medical Center and University of California, San Francisco, California 94121, USA
J Bone Miner Res 19:224-34. 2004..These data show a new role for DAP12 signaling in regulating formation of multinucleated osteoclasts...
TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosisThomas T Chen
Veterans Administration Medical Center, San Francisco, CA 94121, USA
J Exp Med 202:955-65. 2005..This is the first identification of a receptor for ferritin and reveals a new role for TIM-2...
TREM2, a DAP12-associated receptor, regulates osteoclast differentiation and functionMary Beth Humphrey
Department of Medicine, VA Medical Center and University of California, San Francisco, California 94121, USA
J Bone Miner Res 21:237-45. 2006..These results provide new evidence that TREM2 regulates OC function independent of its effects on multinucleated OC differentiation...
