R Kelly Dawe

Summary

Affiliation: University of Georgia
Country: USA

Publications

  1. ncbi request reprint Transformation of rice with long DNA-segments consisting of random genomic DNA or centromere-specific DNA
    Bao H Phan
    Department of Crop and Soil Sciences, University of Georgia, 111 Riverbend Road, Athens, GA 30602, USA
    Transgenic Res 16:341-51. 2007
  2. pmc Widespread gene conversion in centromere cores
    Jinghua Shi
    Department of Plant Biology, University of Georgia, Athens, Georgia, United States of America
    PLoS Biol 8:e1000327. 2010
  3. pmc Maize chromosomal knobs are located in gene-dense areas and suppress local recombination
    Rashin Ghaffari
    Department of Plant Biology, University of Georgia, Athens, GA, USA
    Chromosoma 122:67-75. 2013
  4. pmc DNA binding of centromere protein C (CENPC) is stabilized by single-stranded RNA
    Yaqing Du
    Department of Plant Biology, University of Georgia, Athens, Georgia, United States of America
    PLoS Genet 6:e1000835. 2010
  5. pmc Strong epigenetic similarity between maize centromeric and pericentromeric regions at the level of small RNAs, DNA methylation and H3 chromatin modifications
    Jonathan I Gent
    Department of Plant Biology, University of Georgia, Athens, Georgia 30602, USA
    Nucleic Acids Res 40:1550-60. 2012
  6. pmc Total centromere size and genome size are strongly correlated in ten grass species
    Han Zhang
    Department of Genetics, University of Georgia, Athens, 30602, USA
    Chromosome Res 20:403-12. 2012
  7. pmc An Arabidopsis tissue-specific RNAi method for studying genes essential to mitosis
    Brunilis Burgos-Rivera
    Department of Genetics, University of Georgia, Athens, Georgia, United States of America
    PLoS ONE 7:e51388. 2012
  8. ncbi request reprint Centromeres put epigenetics in the driver's seat
    R Kelly Dawe
    Department of Plant Biology, University of Georgia, Athens, GA 30602, USA
    Trends Biochem Sci 31:662-9. 2006
  9. ncbi request reprint Plant neocentromeres: fast, focused, and driven
    R Kelly Dawe
    Department of Genetics University of Georgia, Athens, GA 30602, USA
    Chromosome Res 12:655-69. 2004
  10. pmc Distinct influences of tandem repeats and retrotransposons on CENH3 nucleosome positioning
    Jonathan I Gent
    Department of Plant Biology, University of Georgia, Athens, Georgia, USA
    Epigenetics Chromatin 4:3. 2011

Collaborators

Detail Information

Publications43

  1. ncbi request reprint Transformation of rice with long DNA-segments consisting of random genomic DNA or centromere-specific DNA
    Bao H Phan
    Department of Crop and Soil Sciences, University of Georgia, 111 Riverbend Road, Athens, GA 30602, USA
    Transgenic Res 16:341-51. 2007
    ....
  2. pmc Widespread gene conversion in centromere cores
    Jinghua Shi
    Department of Plant Biology, University of Georgia, Athens, Georgia, United States of America
    PLoS Biol 8:e1000327. 2010
    ..We conclude that gene conversion accelerates centromere evolution by facilitating sequence exchange among chromosomes...
  3. pmc Maize chromosomal knobs are located in gene-dense areas and suppress local recombination
    Rashin Ghaffari
    Department of Plant Biology, University of Georgia, Athens, GA, USA
    Chromosoma 122:67-75. 2013
    ..These effects do not extend beyond regions ~10 cM to either side of knobs and do not appear to affect linkage disequilibrium among genes within and near knob repeat regions of the B73 RefGen_v2 assembly...
  4. pmc DNA binding of centromere protein C (CENPC) is stabilized by single-stranded RNA
    Yaqing Du
    Department of Plant Biology, University of Georgia, Athens, Georgia, United States of America
    PLoS Genet 6:e1000835. 2010
    ..The data suggest that centromeric RNA helps to recruit CENPC to the inner kinetochore by altering its DNA binding characteristics...
  5. pmc Strong epigenetic similarity between maize centromeric and pericentromeric regions at the level of small RNAs, DNA methylation and H3 chromatin modifications
    Jonathan I Gent
    Department of Plant Biology, University of Georgia, Athens, Georgia 30602, USA
    Nucleic Acids Res 40:1550-60. 2012
    ....
  6. pmc Total centromere size and genome size are strongly correlated in ten grass species
    Han Zhang
    Department of Genetics, University of Georgia, Athens, 30602, USA
    Chromosome Res 20:403-12. 2012
    ..Centromere size may be determined by a limiting component mechanism similar to that described for Caenorhabditis elegans centrosomes...
  7. pmc An Arabidopsis tissue-specific RNAi method for studying genes essential to mitosis
    Brunilis Burgos-Rivera
    Department of Genetics, University of Georgia, Athens, Georgia, United States of America
    PLoS ONE 7:e51388. 2012
    ....
  8. ncbi request reprint Centromeres put epigenetics in the driver's seat
    R Kelly Dawe
    Department of Plant Biology, University of Georgia, Athens, GA 30602, USA
    Trends Biochem Sci 31:662-9. 2006
    ..We propose that key kinetochore proteins have adapted to disrupt such sequence-specific interactions and restore epigenetic inheritance...
  9. ncbi request reprint Plant neocentromeres: fast, focused, and driven
    R Kelly Dawe
    Department of Genetics University of Georgia, Athens, GA 30602, USA
    Chromosome Res 12:655-69. 2004
    ..In addition, we compare and contrast neocentromere-mediated meiotic drive with a recently proposed meiotic drive model for centromere evolution...
  10. pmc Distinct influences of tandem repeats and retrotransposons on CENH3 nucleosome positioning
    Jonathan I Gent
    Department of Plant Biology, University of Georgia, Athens, Georgia, USA
    Epigenetics Chromatin 4:3. 2011
    ..abstract:..
  11. pmc Centromere renewal and replacement in the plant kingdom
    R Kelly Dawe
    Department of Plant Biology, University of Georgia, Miller Plant Sciences Building, Athens, GA 30602, USA
    Proc Natl Acad Sci U S A 102:11573-4. 2005
  12. ncbi request reprint Maize NDC80 is a constitutive feature of the central kinetochore
    Yaqing Du
    Department of Plant Biology, University of Georgia, Athens, GA 30602, USA
    Chromosome Res 15:767-75. 2007
    ..The data suggest that in plants NDC80 is on par with 'foundation' kinetochore proteins such as CENH3 and CENP-C...
  13. pmc The maize Ab10 meiotic drive system maps to supernumerary sequences in a large complex haplotype
    Rebecca J Mroczek
    Department of Plant Biology, University of Georgia, Athens, Georgia 30602, USA
    Genetics 174:145-54. 2006
    ..These and other data suggest that the Ab10 meiotic drive system was initially acquired from a related species and that a complex haplotype evolved around it...
  14. pmc Phosphoserines on maize CENTROMERIC HISTONE H3 and histone H3 demarcate the centromere and pericentromere during chromosome segregation
    Xiaolan Zhang
    Department of Plant Biology, University of Georgia, Athens, Georgia 30602, USA
    Plant Cell 17:572-83. 2005
    ..We propose that a centromere-initiated wave of histone phosphorylation is an early step in defining the two major structural domains required for chromosome segregation: centromere (alignment, motility) and pericentromere (cohesion)...
  15. pmc Precise centromere mapping using a combination of repeat junction markers and chromatin immunoprecipitation-polymerase chain reaction
    Amy C Luce
    Department of Plant Biology, University of Georgia, Georgia 30602, USA
    Genetics 174:1057-61. 2006
    ..Repeat junction mapping was combined with anti-CENH3-mediated ChIP to provide a definitive map position for maize centromere 8...
  16. pmc Centromere-encoded RNAs are integral components of the maize kinetochore
    Christopher N Topp
    Departments of Plant Biology and Genetics, University of Georgia, Athens, GA 30602, USA
    Proc Natl Acad Sci U S A 101:15986-91. 2004
    ..The bulk of the immunoprecipitated RNA ranged in size from 40 to 200 nt. These data provide evidence for a pool of protected, single-stranded centromeric RNA within the centromere/kinetochore complex...
  17. ncbi request reprint The meiotic drive system on maize abnormal chromosome 10 contains few essential genes
    Evelyn N Hiatt
    Department of Genetics, University of Georgia, Athens, GA 30602, USA
    Genetica 117:67-76. 2003
    ..These and other published data suggest that meiotic drive systems tend to evolve in gene-sparse or otherwise information-poor regions of the genome where they are less likely to negatively affect individual fitness...
  18. pmc Four loci on abnormal chromosome 10 contribute to meiotic drive in maize
    Evelyn N Hiatt
    Department of Genetics, University of Georgia, Athens 30602, USA
    Genetics 164:699-709. 2003
    ..These results demonstrate that neocentromere activity and increased recombination are not the only events required for meiotic drive...
  19. pmc Centromeric retroelements and satellites interact with maize kinetochore protein CENH3
    Cathy Xiaoyan Zhong
    Department of Plant Biology, University of Georgia, Athens, Georgia 30602, USA
    Plant Cell 14:2825-36. 2002
    ..Approximately 38 and 33% of CentC and CRM are precipitated in the chromatin immunoprecipitation assay, consistent with data showing that much, but not all, of CENH3 colocalizes with CentC...
  20. pmc CHH islands: de novo DNA methylation in near-gene chromatin regulation in maize
    Jonathan I Gent
    Department of Plant Biology, University of Georgia, Athens, Georgia 30602, USA
    Genome Res 23:628-37. 2013
    ....
  21. pmc Partitioning of the maize epigenome by the number of methyl groups on histone H3 lysines 9 and 27
    Jinghua Shi
    Department of Pathology, University of Georgia, Athens, Georgia 30602, USA
    Genetics 173:1571-83. 2006
    ..Each methylation state identifies different regions of the epigenome. We discuss the evolutionary lability of histone methylation profiles and draw a distinction between H3K9me2-mediated gene silencing and heterochromatin formation...
  22. pmc Intragenomic conflict between the two major knob repeats of maize
    Lisa B Kanizay
    Department of Plant Biology, University of Georgia, Athens, Georgia 30602, USA
    Genetics 194:81-9. 2013
    ..Our results support the general concept that tandem repeat arrays can engage in arms-race-like struggles and proliferate as an outcome...
  23. doi request reprint Fused sister kinetochores initiate the reductional division in meiosis I
    Xuexian Li
    Department of Plant Biology, University of Georgia, Athens, 30602, USA
    Nat Cell Biol 11:1103-8. 2009
    ..The data establish that sister kinetochores in meiosis I are fused by a shared microtubule-binding face and that this direct linkage is required for reductional division...
  24. pmc RNA interference, transposons, and the centromere
    R Kelly Dawe
    Department of Plant Biology, University of Georgia Athens, GA 30602, USA
    Plant Cell 15:297-301. 2003
  25. doi request reprint RNA as a structural and regulatory component of the centromere
    Jonathan I Gent
    Department of Plant Biology, University of Georgia, Athens, Georgia 30602, USA
    Annu Rev Genet 46:443-53. 2012
    ..We also review literature suggesting that the process of centromeric transcription may be as important as the resulting RNA and that such transcription may be involved in recruiting the centromeric histone variant CENH3...
  26. doi request reprint Stable integration of an engineered megabase repeat array into the maize genome
    Han Zhang
    Department of Genetics, University of Georgia, Athens, GA 30602, USA
    Plant J 70:357-65. 2012
    ..It is anticipated that these experimental approaches will be useful for future applications in artificial chromosome design...
  27. ncbi request reprint LumberJack: a heuristic tool for sequence alignment exploration and phylogenetic inference
    Carolyn J Lawrence
    Department of Plant Biology, The University of Georgia, Athens 30602, USA
    Bioinformatics 20:1977-9. 2004
    ..To determine whether any of the topologies generated is significantly more likely than the others, Kishino-Hasegawa, Shimodaira-Hasegawa and ELW tests are implemented. Availability and..
  28. pmc Spreading of heterochromatin is limited to specific families of maize retrotransposons
    Steven R Eichten
    Microbial and Plant Genomics Institute, Department of Plant Biology, University of Minnesota, Saint Paul, Minnesota, United States of America
    PLoS Genet 8:e1003127. 2012
    ..Our findings suggest that a subset of retrotransposon families may act as controlling elements influencing neighboring sequences, while the majority of retrotransposons have little effect on flanking sequences...
  29. pmc Independently regulated neocentromere activity of two classes of tandem repeat arrays
    Evelyn N Hiatt
    Department of Genetics, University of Georgia, Athens, Georgia 30602, USA
    Plant Cell 14:407-20. 2002
    ..Neocentromere-mediated drive provides a plausible mechanism for the evolution and maintenance of repeat arrays that occur in interstitial positions...
  30. pmc Distribution of retroelements in centromeres and neocentromeres of maize
    Rebecca J Mroczek
    Department of Plant Biology, University of Georgia, Athens, Georgia 30602, USA
    Genetics 165:809-19. 2003
    ..CR elements may have evolved mutualistic relationships with their plant hosts: they are known to interact with the kinetochore protein CENH3 and appear to accumulate in clusters, leaving long satellite arrays intact...
  31. ncbi request reprint Reinterpreting pericentromeric heterochromatin
    Christopher N Topp
    Department of Plant Biology, University of Georgia, Athens, Georgia 30602, USA
    Curr Opin Plant Biol 9:647-53. 2006
    ..The available data from plants suggest that sister chromatid cohesion is marked by histone phosphorylation and mediated by Aurora kinases...
  32. doi request reprint Centromeres: long intergenic spaces with adaptive features
    Lisa Kanizay
    Department of Plant Biology, Miller Plant Science Bldg, University of Georgia, Athens, GA 30602, USA
    Funct Integr Genomics 9:287-92. 2009
    ..On genetic maps centromeres appear as long intergenic spaces that evolve rapidly and apparently without regard to host fitness...
  33. doi request reprint Mechanisms of plant spindle formation
    Han Zhang
    Department of Genetics, University of Georgia, Athens, GA 30602, USA
    Chromosome Res 19:335-44. 2011
    ....
  34. ncbi request reprint Maximum likelihood methods reveal conservation of function among closely related kinesin families
    Carolyn J Lawrence
    University of Georgia, Department of Botany, Athens, GA 30602, USA
    J Mol Evol 54:42-53. 2002
    ..In addition, we found that one monophyletic clade composed exclusively of sequences with a C-terminal motor domain contains all known minus end-directed kinesins...
  35. pmc A standardized kinesin nomenclature
    Carolyn J Lawrence
    Department of Plant Biology, The University of Georgia, Athens, GA 30602, USA
    J Cell Biol 167:19-22. 2004
    ..The scheme unifies all previous phylogenies and nomenclature proposals, while allowing individual sequence names to remain the same, and for expansion to occur as new sequences are discovered...
  36. pmc Maize centromeres: organization and functional adaptation in the genetic background of oat
    Weiwei Jin
    Department of Horticulture, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    Plant Cell 16:571-81. 2004
    ..We further demonstrate that in the chromosomal addition lines in which two CenH3 genes were present, one from oat and one from maize, the oat CENH3 was consistently incorporated by the maize centromeres...
  37. ncbi request reprint RNA interference on chromosomes
    R Kelly Dawe
    Nat Genet 36:1141-2. 2004
  38. pmc Molecular and cytological analyses of large tracks of centromeric DNA reveal the structure and evolutionary dynamics of maize centromeres
    Kiyotaka Nagaki
    Department of Horticulture, University of Wisconsin, Madison, Wisconsin 53706, USA
    Genetics 163:759-70. 2003
    ..Highly conserved sequence motifs were found in the LTRs of the centromere-specific retrotransposons in the grass species, suggesting that the LTRs may be important for the centromere specificity of this retrotransposon family...
  39. pmc Chromatin immunoprecipitation reveals that the 180-bp satellite repeat is the key functional DNA element of Arabidopsis thaliana centromeres
    Kiyotaka Nagaki
    Department of Horticulture, University of Wisconsin, Madison, Wisconsin 53706, USA
    Genetics 163:1221-5. 2003
    ..ChIP assays showed that the 180-bp centromeric satellite repeat was precipitated with the antibody, suggesting that this repeat is the key component of the centromere/kinetochore complex in Arabidopsis...
  40. pmc Marcus rhoades, preferential segregation and meiotic drive
    James A Birchler
    Division of Biological Sciences, University of Missouri, Columbia, Missouri 65211, USA
    Genetics 164:835-41. 2003
  41. ncbi request reprint A molecular view of plant centromeres
    Jiming Jiang
    Department of Horticulture, University of Wisconsin Madison, Madison, WI 53706, USA
    Trends Plant Sci 8:570-5. 2003
    ..CR elements as well as their flanking centromeric satellite DNA are actively transcribed in maize. These data suggest that the deposition of centromeric histones might be a transcription-coupled event...
  42. pmc Molecular and functional dissection of the maize B chromosome centromere
    Weiwei Jin
    Department of Horticulture, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    Plant Cell 17:1412-23. 2005
    ..Our results demonstrate that the amount of CENH3 at the B centromere can be varied, but with decreasing amounts, the function of the centromere becomes impaired...
  43. pmc Engineered plant minichromosomes: a bottom-up success?
    Andreas Houben
    Leibniz Institute of Plant Genetics andCrop Plant Research, D 06466 Gatersleben, Germany
    Plant Cell 20:8-10. 2008