Research Topics
Species | Jerry DavisonSummaryAffiliation: University of Washington Country: USA Publications
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Publications
Large-scale polymorphism of heterochromatic repeats in the DNA of Arabidopsis thalianaJerry Davison
University of Washington, Department of Biology, Box 355325, Seattle, WA 98195 5325, USA
BMC Plant Biol 7:44. 2007..Even for a sequenced genome such as that of the model plant Arabidopsis thaliana accession Col-0, the large arrays of heterochromatic repeats are incompletely sequenced, with gaps of uncertain size persisting in them...
G9a/GLP-dependent histone H3K9me2 patterning during human hematopoietic stem cell lineage commitmentXiaoji Chen
Molecular and Cell Biology MCB Program, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
Genes Dev 26:2499-511. 2012..These results suggest that G9a/GLP activity promotes progressive H3K9me2 patterning during HSPC lineage specification and that its inhibition delays HSPC lineage commitment. They also inform clinical manipulation of donor-derived HSPCs...
MYC-driven tumorigenesis is inhibited by WRN syndrome gene deficiencyRussell Moser
Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Mol Cancer Res 10:535-45. 2012..This leads to inhibition of tumor growth and prolonged tumor-free survival. Targeting WRN or its enzymatic function could prove to be an effective strategy in the treatment of MYC-associated cancers...
Remodeling of DNA methylation and phenotypic and transcriptional changes in synthetic Arabidopsis allotetraploidsAndreas Madlung
Department of Botany, Box 355325, University of Washington, Seattle, WA 98195, USA
Plant Physiol 129:733-46. 2002..We show that DNA demethylation induced and repressed two different transcriptomes. Our results are consistent with the hypothesis that synthetic allotetraploids have compromised mechanisms of epigenetic gene regulation...
Genome-wide MyoD binding in skeletal muscle cells: a potential for broad cellular reprogrammingYi Cao
Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Dev Cell 18:662-74. 2010..Therefore, in addition to regulating muscle gene expression, MyoD binds genome wide and has the ability to broadly alter the epigenome in myoblasts and myotubes...
Genomic differences between estrogen receptor (ER)-positive and ER-negative human breast carcinoma identified by single nucleotide polymorphism array comparative genome hybridization analysisMin Fang
Fired Hutchinson Cancer Research Center, Seattle, WA 98109 1023, USA
Cancer 117:2024-34. 2011..The authors used single-nucleotide polymorphism (SNP) arrays to compare overall copy number aberrations (CNAs) as well as loss of heterozygosity (LOH) of the entire human genome in ER-positive and ER-negative breast carcinomas...
