Research Topics
Species | Stephanie D DavisSummaryAffiliation: University of North Carolina Country: USA Publications
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Detail Information
Publications
Multicenter evaluation of infant lung function tests as cystic fibrosis clinical trial endpointsStephanie D Davis
Department of Pediatrics, North Carolina Children s Hospital, University of North Carolina at Chapel Hill, USA
Am J Respir Crit Care Med 182:1387-97. 2010..The conducting of clinical trials in infants with cystic fibrosis (CF) has been hindered by lack of sensitive outcome measures...
Computed tomography reflects lower airway inflammation and tracks changes in early cystic fibrosisStephanie D Davis
Division of Pediatric Pulmonology, Chapel Hill, NC 27599 7220, USA
Am J Respir Crit Care Med 175:943-50. 2007..Detecting and tracking early cystic fibrosis (CF) lung disease are difficult due to lack of sensitive markers of airway dysfunction...
Endpoints for clinical trials in young children with cystic fibrosisStephanie D Davis
Division of Pulmonology, Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Proc Am Thorac Soc 4:418-30. 2007..Further development of these outcomes measures will enable clinical trials in the youngest CF population with the objective of improving long-term prognosis...
Association of lower airway inflammation with physiologic findings in young children with cystic fibrosisStacey L Peterson-Carmichael
Division of Pulmonology, Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Pediatr Pulmonol 44:503-11. 2009....
Mutations of DNAH11 in patients with primary ciliary dyskinesia with normal ciliary ultrastructureMichael R Knowles
University of North Carolina, Cystic Fibrosis Pulmonary Research and Treatment Center, School of Medicine, CB 7248, 7123 Thurston Bowles Bldg, Chapel Hill, NC 27599 7248, USA
Thorax 67:433-41. 2012....
Improvement in pulmonary function following antibiotics in infants with cystic fibrosisJessica E Pittman
Division of Pediatric Pulmonology, University of North Carolina at Chapel Hill, 130 Mason Farm Road, Chapel Hill, NC 27599, USA
Pediatr Pulmonol 47:441-6. 2012..While pulmonary function testing (PFT) is often used to follow progression of lung disease and guide treatment in older children with CF, little data is available on change in infant PFTs in young children with CF...
Physiologic, bronchoscopic, and bronchoalveolar lavage fluid findings in young children with recurrent wheeze and coughJohn Saito
Division of Pulmonology, Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7220, USA
Pediatr Pulmonol 41:709-19. 2006....
Clinical and genetic aspects of primary ciliary dyskinesia/Kartagener syndromeMargaret W Leigh
Department of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA
Genet Med 11:473-87. 2009....
Early lung disease in young children with primary ciliary dyskinesiaDavid E Brown
Department of Pediatrics, Division of Pulmonology, University of North Carolina, Chapel Hill, North Carolina, USA
Pediatr Pulmonol 43:514-6. 2008..We report on 3 young children with PCD who had evidence of lung disease on infant pulmonary function testing, bronchoscopy, and/or computed tomography (CT) of the chest before 3 years of age...
Safety and tolerability of inhaled hypertonic saline in young children with cystic fibrosisElisabeth P Dellon
Department of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599 7217, USA
Pediatr Pulmonol 43:1100-6. 2008..Initiating therapies in young patients has potential to preserve lung function. Before conducting a therapeutic trial of HS in this population, its safety must be evaluated and protocols for monitoring response must be tested...
Variability of a closed, rebreathing setup for multiple breath wash-out testing in childrenJessica E Pittman
Division of Pediatric Pulmonology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Pediatr Pulmonol 47:1242-50. 2012..S. Our objective was to assess validity and sensitivity of a commercially available device that uses a closed (rebreathing) setup with photoacoustic spectroscopy for MBW testing...
Exhaled breath condensate purines correlate with lung function in infants and preschoolersKavita Patel
Department of Pediatric Pulmonology, University of North Carolina, Chapel Hill, North Carolina
Pediatr Pulmonol 48:182-7. 2013..Measurement of exhaled breath condensate (EBC) purines and other biomarkers offers a less invasive method to assess airway inflammation; however, the feasibility and utility of EBC biomarkers in young children has not been established...
Quality of pulmonary function testing in 3 large primary care pediatric clinics in rural North CarolinaChris Gillette
Eshelman School of Pharmacy, University of North Carolina Chapel Hill, Chapel Hill, NC 27599, USA
N C Med J 72:105-10. 2011..Pulmonary function testing (eg, spirometry) is recommended by the National Heart, Lung, and Blood Institute as part of basic asthma management. Previous research has shown that spirometry is feasible in primary care settings...
Neonatal and pediatric respiratory diagnosticsStephanie D Davis
Department of Pediatrics, University of North Carolina at Chapel Hill, 27599 7220, USA
Respir Care 48:367-84; discussion 384-5. 2003..These remarkable advances have yet to be applied in multicenter trials with young children. Adhering to standards will be critical for future multicenter trials to assess the clinical utility of these potential outcome measures...
Reduced lung function in cystic fibrosis: a primary or secondary phenotype?Stephanie D Davis
Am J Respir Crit Care Med 178:2-3. 2008
An official American Thoracic Society/European Respiratory Society statement: pulmonary function testing in preschool childrenNicole Beydon
Am J Respir Crit Care Med 175:1304-45. 2007
