M Wayne Davis

Summary

Affiliation: University of Utah
Country: USA

Publications

  1. pmc A mutation in the C. elegans EXP-2 potassium channel that alters feeding behavior
    M W Davis
    Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9148, USA
    Science 286:2501-4. 1999
  2. pmc Rapid single nucleotide polymorphism mapping in C. elegans
    M Wayne Davis
    Department of Biology, University of Utah, Salt Lake City, Utah 84112 0840, USA
    BMC Genomics 6:118. 2005
  3. pmc Gene activation using FLP recombinase in C. elegans
    M Wayne Davis
    Howard Hughes Medical Institute, University of Utah, Salt Lake City, Utah, United States of America
    PLoS Genet 4:e1000028. 2008
  4. pmc Protons act as a transmitter for muscle contraction in C. elegans
    Asim A Beg
    Neuroscience Program, University of Utah, Salt Lake City, UT 84112 0840, USA
    Cell 132:149-60. 2008
  5. pmc Single-copy insertion of transgenes in Caenorhabditis elegans
    Christian Frøkjaer-Jensen
    Department of Biology and Howard Hughes Medical Institute, University of Utah, 257 South 1400 East, Salt Lake City, Utah 84112, USA
    Nat Genet 40:1375-83. 2008
  6. ncbi request reprint Single-nucleotide polymorphism mapping
    M Wayne Davis
    Department of Biology, University of Utah, Salt Lake City, USA
    Methods Mol Biol 351:75-92. 2006
  7. pmc Heterozygous insertions alter crossover distribution but allow crossover interference in Caenorhabditis elegans
    Marc Hammarlund
    Department of Biology, University of Utah, Salt Lake City, Utah 84112 0840, USA
    Genetics 171:1047-56. 2005
  8. pmc Targeted gene deletions in C. elegans using transposon excision
    Christian Frøkjaer-Jensen
    Howard Hughes Medical Institute, Department of Biology, University of Utah, Salt Lake City, Utah, USA
    Nat Methods 7:451-3. 2010
  9. pmc Protein localization in electron micrographs using fluorescence nanoscopy
    Shigeki Watanabe
    Department of Biology and Howard Hughes Medical Institute, University of Utah, Salt Lake City, Utah, USA
    Nat Methods 8:80-4. 2011
  10. pmc UNC119 is required for G protein trafficking in sensory neurons
    Houbin Zhang
    Department of Ophthalmology, University of Utah Health Science Center, Salt Lake City, Utah, USA
    Nat Neurosci 14:874-80. 2011

Collaborators

Detail Information

Publications17

  1. pmc A mutation in the C. elegans EXP-2 potassium channel that alters feeding behavior
    M W Davis
    Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9148, USA
    Science 286:2501-4. 1999
    ....
  2. pmc Rapid single nucleotide polymorphism mapping in C. elegans
    M Wayne Davis
    Department of Biology, University of Utah, Salt Lake City, Utah 84112 0840, USA
    BMC Genomics 6:118. 2005
    ..In C. elegans, single nucleotide polymorphisms (SNPs) can function as silent genetic markers, with applications ranging from classical two- and three-factor mapping to measuring recombination across whole chromosomes...
  3. pmc Gene activation using FLP recombinase in C. elegans
    M Wayne Davis
    Howard Hughes Medical Institute, University of Utah, Salt Lake City, Utah, United States of America
    PLoS Genet 4:e1000028. 2008
    ..We show that we can use this to inactivate synaptic transmission in all neurons or a subset of neurons in a FLP-dependent manner...
  4. pmc Protons act as a transmitter for muscle contraction in C. elegans
    Asim A Beg
    Neuroscience Program, University of Utah, Salt Lake City, UT 84112 0840, USA
    Cell 132:149-60. 2008
    ..8. The identification of the mechanisms for release and reception of proton signals establishes a highly unusual mechanism for intercellular communication...
  5. pmc Single-copy insertion of transgenes in Caenorhabditis elegans
    Christian Frøkjaer-Jensen
    Department of Biology and Howard Hughes Medical Institute, University of Utah, 257 South 1400 East, Salt Lake City, Utah 84112, USA
    Nat Genet 40:1375-83. 2008
    ..We have successfully inserted transgenes as long as 9 kb and verified that single copies are inserted at the targeted site. Single-copy transgenes are expressed at endogenous levels and can be expressed in the female and male germlines...
  6. ncbi request reprint Single-nucleotide polymorphism mapping
    M Wayne Davis
    Department of Biology, University of Utah, Salt Lake City, USA
    Methods Mol Biol 351:75-92. 2006
    ..This chapter presents a detailed procedure for generating recombinant animals, for assaying SNPs using restriction enzymes, and for analyzing mapping data...
  7. pmc Heterozygous insertions alter crossover distribution but allow crossover interference in Caenorhabditis elegans
    Marc Hammarlund
    Department of Biology, University of Utah, Salt Lake City, Utah 84112 0840, USA
    Genetics 171:1047-56. 2005
    ..However, because crossovers are not completely eliminated distal to insertions, we propose that alignment can be reestablished after a megabase-scale gap in sequence homology...
  8. pmc Targeted gene deletions in C. elegans using transposon excision
    Christian Frøkjaer-Jensen
    Howard Hughes Medical Institute, Department of Biology, University of Utah, Salt Lake City, Utah, USA
    Nat Methods 7:451-3. 2010
    ..Repair can delete up to 25 kb of DNA and simultaneously insert a positive selection marker...
  9. pmc Protein localization in electron micrographs using fluorescence nanoscopy
    Shigeki Watanabe
    Department of Biology and Howard Hughes Medical Institute, University of Utah, Salt Lake City, Utah, USA
    Nat Methods 8:80-4. 2011
    ..Fluorescence correlated with organelles imaged in electron micrographs from the same sections. We used these methods to localize histones, a mitochondrial protein and a presynaptic dense projection protein in electron micrographs...
  10. pmc UNC119 is required for G protein trafficking in sensory neurons
    Houbin Zhang
    Department of Ophthalmology, University of Utah Health Science Center, Salt Lake City, Utah, USA
    Nat Neurosci 14:874-80. 2011
    ..UNC119 deletion in both mouse and C. elegans led to G protein mislocalization. Thus, UNC119 is a Gα subunit cofactor essential for G protein trafficking in sensory cilia...
  11. doi request reprint Ultrafast endocytosis at mouse hippocampal synapses
    Shigeki Watanabe
    Department of Biology and Howard Hughes Medical Institute, University of Utah, Salt Lake City 84112, Utah, USA
    Nature 504:242-7. 2013
    ..It is likely that 'ultrafast endocytosis' is specialized to restore the surface area of the membrane rapidly...
  12. pmc Induction and repair of zinc-finger nuclease-targeted double-strand breaks in Caenorhabditis elegans somatic cells
    Jason Morton
    Department of Biochemistry, University of Utah School of Medicine, 15 North Medical Drive East, Salt Lake City, UT 84112, USA
    Proc Natl Acad Sci U S A 103:16370-5. 2006
    ..DNA ligase IV is required for efficient end joining, particularly of blunt ends. In its absence, a secondary end-joining pathway relies more heavily on microhomologies in producing deletions...
  13. ncbi request reprint A conserved metalloprotease mediates ecdysis in Caenorhabditis elegans
    M Wayne Davis
    Department of Biology, University of Utah, Salt Lake City, UT 84112 0840, USA
    Development 131:6001-8. 2004
    ..NAS-37 degradation of the Haemonchus cuticle suggests that the metalloproteases and the cuticle substrates involved in exsheathment of parasitic nematodes are conserved in free-living nematodes...
  14. ncbi request reprint Mobilization of a Drosophila transposon in the Caenorhabditis elegans germ line
    J L Bessereau
    Department of Biology, University of Utah, Salt Lake City 84112-0840, USA
    Nature 413:70-4. 2001
    ..Fourth, these insertions can subsequently be remobilized to generate deletion and frameshift mutations by imperfect excision...
  15. ncbi request reprint Mutations in the Caenorhabditis elegans Na,K-ATPase alpha-subunit gene, eat-6, disrupt excitable cell function
    M W Davis
    Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas 75235 9038, USA
    J Neurosci 15:8408-18. 1995
    ..To explain these abnormalities, we propose that a reduction of Na,K-ATPase activity in eat-6 mutants leads to a reduction of the ion concentration gradients that power membrane potential changes...
  16. pmc Gene conversion and end-joining-repair double-strand breaks in the Caenorhabditis elegans germline
    Valérie J Robert
    Ecole Normale Superieure, Biologie Cellulaire de la Synapse, Paris, France
    Genetics 180:673-9. 2008
    ..Surprisingly, expression of the transposase using an intestine-specific promoter can induce repair, raising the possibility that activation of transposase expression in somatic cells can lead to transposition of Mos1 in the germline...
  17. ncbi request reprint Social feeding in Caenorhabditis elegans is induced by neurons that detect aversive stimuli
    Mario de Bono
    Howard Hughes Medical Institute, Department of Anatomy, UCSF, California 94143 0452, USA
    Nature 419:899-903. 2002
    ..Our data suggest a model for regulation of social feeding by opposing sensory inputs: aversive inputs to nociceptive neurons promote social feeding, whereas antagonistic inputs from neurons that express osm-3 inhibit aggregation...