Richard J Davidson

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. ncbi request reprint What does the prefrontal cortex "do" in affect: perspectives on frontal EEG asymmetry research
    Richard J Davidson
    Laboratory for Affective Neuroscience, W M Keck Laboratory for Functional Neuroimaging and Behavior, University of Wisconsin Madison, 1202 West Johnson Street, Madison, WI 53706, USA
    Biol Psychol 67:219-33. 2004
  2. pmc Amygdalar and hippocampal substrates of anxious temperament differ in their heritability
    Jonathan A Oler
    Department of Psychiatry, University of Wisconsin Madison, Madison, Wisconsin 53719, USA
    Nature 466:864-8. 2010
  3. pmc Relationships between changes in sustained fronto-striatal connectivity and positive affect in major depression resulting from antidepressant treatment
    Aaron S Heller
    Departments of Psychology and Psychiatry, University of Wisconsin Madison, WI, USA
    Am J Psychiatry 170:197-206. 2013
  4. ncbi request reprint Failure to regulate: counterproductive recruitment of top-down prefrontal-subcortical circuitry in major depression
    Tom Johnstone
    Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin Madison, Madison, Wisconsin 53705, USA
    J Neurosci 27:8877-84. 2007
  5. ncbi request reprint Gaze fixations predict brain activation during the voluntary regulation of picture-induced negative affect
    Carien M van Reekum
    Laboratory for Affective Neuroscience, Department of Psychology, University of Wisconsin Madison, Madison, WI 53706, USA
    Neuroimage 36:1041-55. 2007
  6. pmc Subgenual prefrontal cortex activity predicts individual differences in hypothalamic-pituitary-adrenal activity across different contexts
    Allison L Jahn
    Department of Psychology, University of Wisconsin Madison, Madison, WI, USA
    Biol Psychiatry 67:175-81. 2010
  7. pmc Orbitofrontal cortex lesions alter anxiety-related activity in the primate bed nucleus of stria terminalis
    Andrew S Fox
    Department of Psychology, University of Wisconsin Madison, Madison, Wisconsin 53719, USA
    J Neurosci 30:7023-7. 2010
  8. ncbi request reprint Individual differences in amygdala and ventromedial prefrontal cortex activity are associated with evaluation speed and psychological well-being
    Carien M van Reekum
    University of Wisconsin Madison, Madison, WI 52706, USA
    J Cogn Neurosci 19:237-48. 2007
  9. ncbi request reprint Amygdala volume and nonverbal social impairment in adolescent and adult males with autism
    Brendon M Nacewicz
    Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin Madison, Waisman Center, 1500 Highland Avenue, Madison, WI 53705, USA
    Arch Gen Psychiatry 63:1417-28. 2006
  10. pmc Neural mechanisms underlying heterogeneity in the presentation of anxious temperament
    Alexander J Shackman
    Department of Psychiatry, University of Wisconsin, Madison, WI 53719, USA
    Proc Natl Acad Sci U S A 110:6145-50. 2013

Detail Information

Publications116 found, 100 shown here

  1. ncbi request reprint What does the prefrontal cortex "do" in affect: perspectives on frontal EEG asymmetry research
    Richard J Davidson
    Laboratory for Affective Neuroscience, W M Keck Laboratory for Functional Neuroimaging and Behavior, University of Wisconsin Madison, 1202 West Johnson Street, Madison, WI 53706, USA
    Biol Psychol 67:219-33. 2004
    ..A number of methodological issues associated with EEG measures of functional prefrontal asymmetries are also considered...
  2. pmc Amygdalar and hippocampal substrates of anxious temperament differ in their heritability
    Jonathan A Oler
    Department of Psychiatry, University of Wisconsin Madison, Madison, Wisconsin 53719, USA
    Nature 466:864-8. 2010
    ..Even though these structures are closely linked, the results suggest differential influences of genes and environment on how these brain regions mediate AT and the ongoing risk of developing anxiety and depression...
  3. pmc Relationships between changes in sustained fronto-striatal connectivity and positive affect in major depression resulting from antidepressant treatment
    Aaron S Heller
    Departments of Psychology and Psychiatry, University of Wisconsin Madison, WI, USA
    Am J Psychiatry 170:197-206. 2013
    ..Studies examining reduced positive affect in a variety of psychiatric disorders might benefit from examining the temporal dynamics of brain activity when attempting to understand changes in daily positive affect...
  4. ncbi request reprint Failure to regulate: counterproductive recruitment of top-down prefrontal-subcortical circuitry in major depression
    Tom Johnstone
    Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin Madison, Madison, Wisconsin 53705, USA
    J Neurosci 27:8877-84. 2007
    ....
  5. ncbi request reprint Gaze fixations predict brain activation during the voluntary regulation of picture-induced negative affect
    Carien M van Reekum
    Laboratory for Affective Neuroscience, Department of Psychology, University of Wisconsin Madison, Madison, WI 53706, USA
    Neuroimage 36:1041-55. 2007
    ..Furthermore, this variation in gaze fixation accounted for substantial amounts of variance in brain activation. These data point to the importance of controlling for gaze fixation in studies of emotion regulation that use visual stimuli...
  6. pmc Subgenual prefrontal cortex activity predicts individual differences in hypothalamic-pituitary-adrenal activity across different contexts
    Allison L Jahn
    Department of Psychology, University of Wisconsin Madison, Madison, WI, USA
    Biol Psychiatry 67:175-81. 2010
    ....
  7. pmc Orbitofrontal cortex lesions alter anxiety-related activity in the primate bed nucleus of stria terminalis
    Andrew S Fox
    Department of Psychology, University of Wisconsin Madison, Madison, Wisconsin 53719, USA
    J Neurosci 30:7023-7. 2010
    ..Thus it appears that an important function of the OFC in response to threat is to modulate the BNST, which may more directly influence the expression of BI...
  8. ncbi request reprint Individual differences in amygdala and ventromedial prefrontal cortex activity are associated with evaluation speed and psychological well-being
    Carien M van Reekum
    University of Wisconsin Madison, Madison, WI 52706, USA
    J Cogn Neurosci 19:237-48. 2007
    ....
  9. ncbi request reprint Amygdala volume and nonverbal social impairment in adolescent and adult males with autism
    Brendon M Nacewicz
    Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin Madison, Waisman Center, 1500 Highland Avenue, Madison, WI 53705, USA
    Arch Gen Psychiatry 63:1417-28. 2006
    ..Autism is a syndrome of unknown cause, marked by abnormal development of social behavior. Attempts to link pathological features of the amygdala, which plays a key role in emotional processing, to autism have shown little consensus...
  10. pmc Neural mechanisms underlying heterogeneity in the presentation of anxious temperament
    Alexander J Shackman
    Department of Psychiatry, University of Wisconsin, Madison, WI 53719, USA
    Proc Natl Acad Sci U S A 110:6145-50. 2013
    ..These findings provide a framework for understanding the mechanisms that lead to heterogeneity in the clinical presentation of internalizing disorders and set the stage for developing improved interventions...
  11. ncbi request reprint Gaze fixation and the neural circuitry of face processing in autism
    Kim M Dalton
    Waisman Center, University of Wisconsin, 1500 Highland Avenue, Madison, Wisconsin 53705 2280, USA
    Nat Neurosci 8:519-26. 2005
    ..In addition, variation in eye fixation within autistic individuals was strongly and positively associated with amygdala activation across both studies, suggesting a heightened emotional response associated with gaze fixation in autism...
  12. ncbi request reprint Amygdala and ventromedial prefrontal cortex are inversely coupled during regulation of negative affect and predict the diurnal pattern of cortisol secretion among older adults
    Heather L Urry
    Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    J Neurosci 26:4415-25. 2006
    ..Individual differences yielded the predicted link between brain function while reducing negative affect in the laboratory and diurnal regulation of endocrine activity in the home environment...
  13. pmc Structural variations in prefrontal cortex mediate the relationship between early childhood stress and spatial working memory
    Jamie L Hanson
    Department of Psychology, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    J Neurosci 32:7917-25. 2012
    ..These results suggest that structural changes in the PFC may serve as a mediating mechanism through which greater cumulative life stress engenders decrements in cognitive functioning...
  14. pmc Reduced right ventrolateral prefrontal cortex activity while inhibiting positive affect is associated with improvement in hedonic capacity after 8 weeks of antidepressant treatment in major depressive disorder
    Sharee N Light
    Center for Investigating Healthy Minds at the Waisman Center, University of Wisconsin Madison, USA
    Biol Psychiatry 70:962-8. 2011
    ..The present study examined another facet of positive emotion regulation associated with anhedonia-namely, the downregulation of positive affect-and its relation to prefrontal cortex (PFC) activity...
  15. pmc General multivariate linear modeling of surface shapes using SurfStat
    Moo K Chung
    Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI 53705, USA
    Neuroimage 53:491-505. 2010
    ..The methodology has been applied for quantifying abnormal local amygdala shape variations in 22 high functioning autistic subjects...
  16. pmc Serotonin transporter availability in the amygdala and bed nucleus of the stria terminalis predicts anxious temperament and brain glucose metabolic activity
    Jonathan A Oler
    Departments of Psychiatry, HealthEmotions Research Institute, University of Wisconsin Madison, 53719, USA
    J Neurosci 29:9961-6. 2009
    ..Collectively, these findings suggest that serotonergic modulation of neuronal excitability in the neural circuitry associated with anxiety mediates the developmental risk for affect-related psychopathology...
  17. ncbi request reprint Event-related functional magnetic resonance imaging measures of neural activity to positive social stimuli in pre- and post-treatment depression
    Hillary S Schaefer
    Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin Madison, Madison, Wisconsin 53705 2280, USA
    Biol Psychiatry 60:974-86. 2006
    ..The neural underpinnings of these relationships, however, have not been explored...
  18. pmc Voluntary facial displays of pain increase suffering in response to nociceptive stimulation
    Tim V Salomons
    Waisman Laboratory for Brain Imaging and Behavior, Waisman Center, Madison, Wisconsin 53705, USA
    J Pain 9:443-8. 2008
    ....
  19. ncbi request reprint Anxiety selectively disrupts visuospatial working memory
    Alexander J Shackman
    Department of Psychology, University of Wisconsin Madison, 59706, USA
    Emotion 6:40-61. 2006
    ..These observations suggest a revision of extant models of how anxiety sculpts cognition and underscore the utility of the desiderata...
  20. ncbi request reprint Functional coupling of simultaneous electrical and metabolic activity in the human brain
    Terrence R Oakes
    W M Keck Laboratory for Functional Brain Imaging and Behavior, University of Wisconsin Madison, Madison, Wisconsin 53705, USA
    Hum Brain Mapp 21:257-70. 2004
    ..This method will be useful in the future when it is applied to functional imaging methods with faster time resolution, such as short half-life PET blood flow tracers and functional magnetic resonance imaging...
  21. ncbi request reprint Amygdalar interhemispheric functional connectivity differs between the non-depressed and depressed human brain
    William Irwin
    Department of Psychology, Laboratory for Affected Neuroscience, University of Wisconsin, Madison, WI 53706, USA
    Neuroimage 21:674-86. 2004
    ..We interpret and discuss the nature of this connectivity in the depressed brain in the context of dysfunctional frontocortical-amygdalar interactions which accompany clinical depression...
  22. pmc Amygdalar function reflects common individual differences in emotion and pain regulation success
    Regina C Lapate
    University of Wisconsin Madison, USA
    J Cogn Neurosci 24:148-58. 2012
    ..These findings suggest that common individual differences in emotion and pain regulatory success are reflected in a neural structure known to contribute to appraisal processes...
  23. pmc Dynamic variation in pleasure in children predicts nonlinear change in lateral frontal brain electrical activity
    Sharee N Light
    University of Wisconsin, Madison, WI 53706, USA
    Dev Psychol 45:525-33. 2009
    ..These findings indicate that task-dependent changes in pleasure relate to dynamic, nonlinear changes in lateral frontal activity as the task unfolds...
  24. pmc Brain regions associated with the expression and contextual regulation of anxiety in primates
    Ned H Kalin
    Department of Psychiatry, University of Wisconsin Madison, Madison, Wisconsin 53719 1176, USA
    Biol Psychiatry 58:796-804. 2005
    ..A key to successful adaptation is the ability to regulate emotional responses in relation to changing environmental demands or contexts...
  25. pmc Stress potentiates early and attenuates late stages of visual processing
    Alexander J Shackman
    Department of Psychology, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    J Neurosci 31:1156-61. 2011
    ..These results provide a novel basis for understanding how stress can modulate information processing in everyday life and stress-sensitive disorders...
  26. ncbi request reprint Brain mechanisms of expectation associated with insula and amygdala response to aversive taste: implications for placebo
    Issidoros Sarinopoulos
    Waisman Laboratory for Brain Imaging and Behavior, Waisman Center, Department of Psychiatry, University of Wisconsin, 1500 Highland Avenue, Madison, WI 53705 2274, USA
    Brain Behav Immun 20:120-32. 2006
    ..Altering expectancies of upcoming aversive events are shown here to depend on robust functional associations among brain regions implicated in prior work on the placebo effect...
  27. pmc Identifying robust and sensitive frequency bands for interrogating neural oscillations
    Alexander J Shackman
    Wisconsin Psychiatric Institute and Clinics, Departments of Psychology and Psychiatry, University of Wisconsin Madison, WI 53706, USA
    Neuroimage 51:1319-33. 2010
    ....
  28. pmc Evidence for coordinated functional activity within the extended amygdala of non-human and human primates
    Jonathan A Oler
    Department of Psychiatry, University of Wisconsin Madison, Madison, WI 53719, USA
    Neuroimage 61:1059-66. 2012
    ..These results support the use of in vivo functional imaging methods in nonhuman and human primates to probe the functional anatomy of major brain networks such as the extended amygdala...
  29. pmc Cortisol's effects on hippocampal activation in depressed patients are related to alterations in memory formation
    Heather C Abercrombie
    University of Wisconsin School of Medicine and Public Health, Department of Psychiatry, Madison, WI, USA
    J Psychiatr Res 45:15-23. 2011
    ..Our data also show that in both depressed men and women, cortisol's effects on emotional memory formation and hippocampal function are related...
  30. pmc Mental training enhances attentional stability: neural and behavioral evidence
    Antoine Lutz
    Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin Madison, Madison, Wisconsin 53705, USA
    J Neurosci 29:13418-27. 2009
    ..These novel findings highlight the mechanisms underlying focused attention meditation and support the notion that mental training can significantly affect attention and brain function...
  31. ncbi request reprint Making a life worth living: neural correlates of well-being
    Heather L Urry
    Department of Psychology and W M Keck Laboratory for Functional Brain Imaging and Behavior, University of Wisconsin Madison, Madison, WI 53706, USA
    Psychol Sci 15:367-72. 2004
    ..Appropriately engaging sources of appetitive motivation, characteristic of higher left than right baseline levels of prefrontal activation, may encourage the experience of well-being...
  32. ncbi request reprint Role of the primate orbitofrontal cortex in mediating anxious temperament
    Ned H Kalin
    Department of Psychiatry, University of Wisconsin Medical School, Madison, Wisconsin 53719 1176, USA
    Biol Psychiatry 62:1134-9. 2007
    ..This study assessed the role of the primate OFC in mediating anxious temperament and its involvement in fear responses...
  33. ncbi request reprint Spatio-temporal dynamics of brain mechanisms in aversive classical conditioning: high-density event-related potential and brain electrical tomography analyses
    Diego A Pizzagalli
    Department of Psychology, University of Wisconsin Madison, 1202 W Johnson Street, Madison, WI 53706, USA
    Neuropsychologia 41:184-94. 2003
    ....
  34. pmc Increased prefrontal cortex activity during negative emotion regulation as a predictor of depression symptom severity trajectory over 6 months
    Aaron S Heller
    Laboratory for Affective Neuroscience, University of Wisconsin, Madison2Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin, Madison3Department of Psychology, University of Wisconsin, Madison
    JAMA Psychiatry 70:1181-9. 2013
    ....
  35. ncbi request reprint Psychological well-being and ill-being: do they have distinct or mirrored biological correlates?
    Carol D Ryff
    Institute on Aging, Medical Science Center, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    Psychother Psychosom 75:85-95. 2006
    ..e. well-being and ill-being correlate similarly with biomarkers, but show opposite directional signs), whereas independence predicts 'distinct' biological correlates (i.e. well-being and ill-being have different biological signatures)...
  36. pmc Developmental pathways to amygdala-prefrontal function and internalizing symptoms in adolescence
    Cory A Burghy
    Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin Madison, Madison, Wisconsin, USA
    Nat Neurosci 15:1736-41. 2012
    ..These data highlight that, for females, the effects of ELS and early HPA-axis function may be detected much later in the intrinsic processing of emotion-related brain circuits...
  37. pmc Amygdala-prefrontal coupling underlies individual differences in emotion regulation
    Hyejeen Lee
    Waisman Laboratory for Brain Imaging and Behavior, Department of Psychology, University of Wisconsin, Madison, WI 53705, USA
    Neuroimage 62:1575-81. 2012
    ..Our results demonstrate that individual differences in emotion regulation are stable over time and underscore the important role of amygdala-prefrontal coupling for successful regulation of negative emotion...
  38. ncbi request reprint Gaze-fixation, brain activation, and amygdala volume in unaffected siblings of individuals with autism
    Kim M Dalton
    Waisman Center, University of Wisconsin, Madison, Wisconsin, USA
    Biol Psychiatry 61:512-20. 2007
    ..These characteristics primarily affect the social aspects of language, communication, and human interaction. The current research focuses on possible neurobehavioral characteristics associated with the broad autism phenotype...
  39. ncbi request reprint Now you feel it, now you don't: frontal brain electrical asymmetry and individual differences in emotion regulation
    Daren C Jackson
    University of Wisconsin Madison, 53706, USA
    Psychol Sci 14:612-7. 2003
    ..This relation between resting frontal activation and recovery following an aversive event supports the idea of a frontally mediated mechanism involved in one form of automatic emotion regulation...
  40. ncbi request reprint Individual differences in the effects of perceived controllability on pain perception: critical role of the prefrontal cortex
    Tim V Salomons
    University of Wisconsin Madison, WI, USA
    J Cogn Neurosci 19:993-1003. 2007
    ....
  41. pmc Differential effects on pain intensity and unpleasantness of two meditation practices
    David M Perlman
    Department of Psychology, University of Wisconsin, Madison, WI 53705, USA
    Emotion 10:65-71. 2010
    ..Implications are discussed in the broader context of training-induced changes in trait emotion regulation...
  42. ncbi request reprint Functional neuroanatomy of aversion and its anticipation
    Jack B Nitschke
    The Waisman Laboratory for Brain Imaging and Behavior, Waisman Center, Department of Psychiatry, University of Wisconsin, 1500 Highland Avenue, Madison, WI 53705 2280, USA
    Neuroimage 29:106-16. 2006
    ..These results show that anticipation of aversion recruits key brain regions that respond to aversion, thereby potentially enhancing adaptive responses to aversive events...
  43. pmc Anticipatory activation in the amygdala and anterior cingulate in generalized anxiety disorder and prediction of treatment response
    Jack B Nitschke
    Departments of Psychiatry and Psychology, University of Wisconsin, Madison, 53705 2280, USA
    Am J Psychiatry 166:302-10. 2009
    ..This study tested whether patients with generalized anxiety disorder have alterations in anticipatory amygdala function and whether anticipatory activity in the anterior cingulate cortex predicts treatment response...
  44. pmc A comparison of mindfulness-based stress reduction and an active control in modulation of neurogenic inflammation
    Melissa A Rosenkranz
    Waisman Laboratory for Brain Imaging and Behavior and Center for Investigating Healthy Minds, University of Wisconsin Madison, 1500 Highland Avenue, Madison, WI 53705, United States
    Brain Behav Immun 27:174-84. 2013
    ..Moreover, mindfulness practice, in particular, may be more efficacious in symptom relief than the well-being promoting activities cultivated in the HEP program...
  45. pmc The voice of emotion: an FMRI study of neural responses to angry and happy vocal expressions
    Tom Johnstone
    Waisman Laboratory for Brain Imaging and Behavior Psychology Department, University of Wisconsin Madison, Madison, WI 53705, USA
    Soc Cogn Affect Neurosci 1:242-9. 2006
    ..Our results identify a network of regions implicated in the processing of vocal emotion, and suggest a particularly salient role for vocal expressions of happiness...
  46. ncbi request reprint Socioeconomic status predicts objective and subjective sleep quality in aging women
    Elliot M Friedman
    Department of Population Health Sciences, University of Wisconsin Madison, Madison, Wisconsin 53726, USA
    Psychosom Med 69:682-91. 2007
    ..Epidemiological studies linking SES and sleep quality have traditionally relied on self-reported assessments of sleep...
  47. pmc Reduced capacity to sustain positive emotion in major depression reflects diminished maintenance of fronto-striatal brain activation
    Aaron S Heller
    Laboratory for Affective Neuroscience, Waisman Laboratory for Brain Imaging and Behavior, Department of Psychology, University of Wisconsin, Madison, WI 53705, USA
    Proc Natl Acad Sci U S A 106:22445-50. 2009
    ..These findings support the hypothesis that anhedonia in depressed patients reflects the inability to sustain engagement of structures involved in positive affect and reward...
  48. pmc Right dorsolateral prefrontal cortical activity and behavioral inhibition
    Alexander J Shackman
    Laboratory for Affective Neuroscience, University of Wisconsin Madison, Madison, WI 53706, USA
    Psychol Sci 20:1500-6. 2009
    ..This observation provides novel support for recent conceptualizations of behavioral inhibition and clues to the mechanisms that might underlie variation in threat-induced negative affect...
  49. pmc The cyclic AMP phenotype of fragile X and autism
    Daniel J Kelley
    Waisman Laboratory for Brain Imaging and Behavior, Waisman Center, University of Wisconsin, Madison, WI, USA
    Neurosci Biobehav Rev 32:1533-43. 2008
    ..Cyclic AMP is a potentially useful biochemical marker to distinguish autism comorbid with FX from autism per se and the cAMP cascade may be a viable therapeutic target for both FX and autism...
  50. pmc Trait-like brain activity during adolescence predicts anxious temperament in primates
    Andrew S Fox
    Department of Psychology, University of Wisconsin Madison, Madison, Wisconsin, United States of America
    PLoS ONE 3:e2570. 2008
    ..In addition, the findings provide an explanation for why individuals with anxious temperament have difficulty relaxing in environments that others perceive as non-stressful...
  51. pmc Early stress is associated with alterations in the orbitofrontal cortex: a tensor-based morphometry investigation of brain structure and behavioral risk
    Jamie L Hanson
    Waisman Center, University of Wisconsin Madison, Madison, Wisconsin 53705, USA
    J Neurosci 30:7466-72. 2010
    ..These data suggest a biological mechanism linking early social learning to later behavioral outcomes...
  52. ncbi request reprint Unattended facial expressions asymmetrically bias the concurrent processing of nonemotional information
    Jeffrey S Maxwell
    Laboratory for Affective Neuroscience, University of Wisconsin Madison, WI 53706, USA
    J Cogn Neurosci 17:1386-95. 2005
    ..By contrast, under high load, only angry distractors produced greater RH than LH interference as a function of anxiety...
  53. ncbi request reprint Orbitofrontal cortex tracks positive mood in mothers viewing pictures of their newborn infants
    Jack B Nitschke
    W M Keck Laboratory for Functional Brain Imaging and Behavior and Laboratory for Affective Neuroscience, Departments of Psychiatry and Psychology, University of Wisconsin, Madison, WI 53705 2280, USA
    Neuroimage 21:583-92. 2004
    ..Furthermore, individual variations in orbitofrontal activation to infant stimuli may reflect an important dimension of maternal attachment...
  54. pmc Are there neurophenotypes for asthma? Functional brain imaging of the interaction between emotion and inflammation in asthma
    Melissa A Rosenkranz
    Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin Madison, Madison, Wisconsin, United States of America
    PLoS ONE 7:e40921. 2012
    ..However, the precise nature of the neural pathways implicated in modulating asthma symptoms is unknown. Moreover, the extent to which variations in neural signaling predict different phenotypes of disease expression has not been studied...
  55. pmc Conscientiousness predicts greater recovery from negative emotion
    Kristin N Javaras
    Laboratory for Affective Neuroscience, Department of Psychology, University of Wisconsin, USA
    Emotion 12:875-81. 2012
    ..In addition, the effect was specific to negative emotional stimuli and did not hold for neutral or positive emotional stimuli...
  56. pmc BOLD signal in insula is differentially related to cardiac function during compassion meditation in experts vs. novices
    Antoine Lutz
    Laboratory for Functional Brain Imaging and Behavior, Waisman Center, University of Wisconsin, 1500 Highland Avenue, Madison, WI 53705, USA
    Neuroimage 47:1038-46. 2009
    ..Future studies are needed to further investigate the impact of compassion training on these circuits...
  57. pmc Electromyogenic artifacts and electroencephalographic inferences
    Alexander J Shackman
    Laboratory for Affective Neuroscience and Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin, W J Brogden Hall, 1202 West Johnson Street, Madison, WI 53706, USA
    Brain Topogr 22:7-12. 2009
    ..We conclude by describing emerging methodological trends in this area that are likely to have substantial benefits for basic and applied EEG research...
  58. pmc High-affinity dopamine D2/D3 PET radioligands 18F-fallypride and 11C-FLB457: a comparison of kinetics in extrastriatal regions using a multiple-injection protocol
    Nicholas T Vandehey
    Department of Medical Physics, University of Wisconsin Madison, Madison, Wisconsin, USA
    J Cereb Blood Flow Metab 30:994-1007. 2010
    ..In the presence of specific D(2)/D(3) binding in the cerebellum, reference region analysis methods will give a greater bias in BP(ND) with (11)C-FLB457 than with (18)F-fallypride...
  59. pmc The integration of negative affect, pain and cognitive control in the cingulate cortex
    Alexander J Shackman
    Department of Psychology, University of Wisconsin, Madison, Wisconsin, WI 53706, USA
    Nat Rev Neurosci 12:154-67. 2011
    ..These observations compel a reconsideration of the dorsal cingulate's contribution to negative affect and pain...
  60. ncbi request reprint Altering expectancy dampens neural response to aversive taste in primary taste cortex
    Jack B Nitschke
    Waisman Laboratory for Brain Imaging and Behavior, Waisman Center, Departments of Psychiatry and Psychology, University of Wisconsin, 1500 Highland Avenue, Madison, Wisconsin 53705 2274, USA
    Nat Neurosci 9:435-42. 2006
    ..In addition, the activation of the right insula and operculum tracked online ratings of the aversiveness for each taste. Such expectancy-driven modulation of primary sensory cortex may affect perceptions of external events...
  61. pmc Simultaneous acquisition of corrugator electromyography and functional magnetic resonance imaging: a new method for objectively measuring affect and neural activity concurrently
    Aaron S Heller
    Department of Psychology University of Wisconsin Madison, Madison, WI 53706, USA
    Neuroimage 58:930-4. 2011
    ..The ability to simultaneously acquire brain activity and facial physiology will allow affective neuroscientists to address theoretical, psychiatric, and individual difference questions in a more rigorous and generalizable way...
  62. pmc The cerebral response during subjective choice with and without self-reference
    Sterling C Johnson
    William S Middleton VA Medical Center, Madison, WI 53705, USA
    J Cogn Neurosci 17:1897-906. 2005
    ..The findings suggest that self-referential processing, rather than subjective judgments among ambiguous response alternatives, accounted for the AMPFC and RSC response...
  63. pmc 4D hyperspherical harmonic (HyperSPHARM) representation of multiple disconnected brain subcortical structures
    Ameer Pasha Hosseinbor
    University of Wisconsin Madison, USA
    Med Image Comput Comput Assist Interv 16:598-605. 2013
    ..HyperSPHARM is shown to achieve a better reconstruction with only 5 basis compared to SPHARM that requires more than 441...
  64. pmc Reliable non-invasive measurement of human neurochemistry using proton spectroscopy with an anatomically defined amygdala-specific voxel
    Brendon M Nacewicz
    Waisman Laboratory for Brain Imaging and Behavior, Room T 225 Waisman Center, 1500 Highland Ave, University of Wisconsin Madison, WI 53705, USA
    Neuroimage 59:2548-59. 2012
    ..Precise, anatomically-based prescriptions that avoid age-related sources of inhomogeneity and use longer scan times may permit study of individual differences in neurochemistry throughout development in this late-maturing structure...
  65. pmc Dynamic Causal Modeling applied to fMRI data shows high reliability
    Brianna Schuyler
    Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin Madison, USA
    Neuroimage 49:603-11. 2010
    ..Also, the DCM analysis uncovers group differences that were not present in the analysis of PSC, which implies that DCM may be more sensitive to the nuances of signal changes in fMRI data...
  66. ncbi request reprint Weighted fourier series representation and its application to quantifying the amount of gray matter
    Moo K Chung
    Department of Statistics, Biostatistics, and Medical Informatics, and the Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin, Madison, WI 53706, USA
    IEEE Trans Med Imaging 26:566-81. 2007
    ..html. As an illustration, the WFS is applied i n quantifying the amount ofgray matter in a group of high functioning autistic subjects. Within the WFS framework, cortical thickness and gray matter density are computed and compared...
  67. ncbi request reprint Acute cortisol elevations cause heightened arousal ratings of objectively nonarousing stimuli
    Heather C Abercrombie
    Department of Psychiatry, University of Wisconsin Madison, Madison, WI 53719, USA
    Emotion 5:354-9. 2005
    ..However, cortisol was unrelated to self-reported affective state. Thus, findings indicate that acute cortisol elevations cause heightened arousal in response to objectively nonarousing stimuli, in the absence of effects on mood...
  68. ncbi request reprint Motion correction and the use of motion covariates in multiple-subject fMRI analysis
    Tom Johnstone
    Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin Madison, Madison, Wisconsin 53705, USA
    Hum Brain Mapp 27:779-88. 2006
    ..Based on these results, we present a general strategy for block designs, event-related designs, and hybrid designs to identify and eliminate probable motion artifacts while maximizing sensitivity to true activations...
  69. pmc Empathy is associated with dynamic change in prefrontal brain electrical activity during positive emotion in children
    Sharee N Light
    University of Wisconsin Madison, WI 53706, USA
    Child Dev 80:1210-31. 2009
    ..05). This suggests that positive affect and (negative and positive) empathy both relate to changes in prefrontal activity during a pleasurable task...
  70. pmc Neural circuitry underlying the interaction between emotion and asthma symptom exacerbation
    Melissa A Rosenkranz
    Department of Psychology, Laboratory for Affective Neuroscience, University of Wisconsin, 1202 West Johnson Street, Madison, WI 53706, USA
    Proc Natl Acad Sci U S A 102:13319-24. 2005
    ....
  71. pmc Theta phase synchrony and conscious target perception: impact of intensive mental training
    Heleen A Slagter
    University of Wisconsin, Madison, WI 53705, USA
    J Cogn Neurosci 21:1536-49. 2009
    ..In combination, these findings illustrate the usefulness of systematic mental training in the study of the human mind by revealing the neural mechanisms that enable the brain to successfully represent target information...
  72. pmc Well-being and affective style: neural substrates and biobehavioural correlates
    Richard J Davidson
    Laboratory for Affective Neuroscience, W M Keck Laboratory for Functional Brain Imaging and Behavior, University of Wisconsin Madison, 1202 West Johnson Street, Madison, WI 53706, USA
    Philos Trans R Soc Lond B Biol Sci 359:1395-411. 2004
    ..The article concludes with a consideration of whether these patterns of central and peripheral biology can be modified by training and shifted toward a more salubrious direction...
  73. ncbi request reprint Neural-cardiac coupling in threat-evoked anxiety
    Kim M Dalton
    W M Keck Laboratory for Functional Brain Imaging and Behavior at the Waisman Center, University of Wisconsin, Madison, 53705, USA
    J Cogn Neurosci 17:969-80. 2005
    ....
  74. pmc Integrating VBM into the General Linear Model with voxelwise anatomical covariates
    Terrence R Oakes
    Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin Madison, Rm T 133, Waisman Center, 1500 Highland Ave, Madison, WI 53705, USA
    Neuroimage 34:500-8. 2007
    ..In either case, ignoring the readily available structural information can lead to misinterpretation of functional results...
  75. pmc The distribution of D2/D3 receptor binding in the adolescent rhesus monkey using small animal PET imaging
    Bradley T Christian
    Department of Psychiatry, University of Wisconsin Madison, USA Department of Medical Physics, University of Wisconsin Madison, USA
    Neuroimage 44:1334-44. 2009
    ..To facilitate comparison within and between primate models, we report in vivo D2/D3 binding in a large cohort of adolescent rhesus monkeys...
  76. ncbi request reprint Anxiety and affective style: role of prefrontal cortex and amygdala
    Richard J Davidson
    Laboratory for Affective Neuroscience, Department of Psychology, University of Wisconsin Madison, 1202 West Johnson Street, Madison, WI 53706, USA
    Biol Psychiatry 51:68-80. 2002
    ..Emphasis is placed on affective chronometry, or the time course of emotional responding, as a key attribute of individual differences in propensity for anxiety that is regulated by this circuitry...
  77. ncbi request reprint The role of the central nucleus of the amygdala in mediating fear and anxiety in the primate
    Ned H Kalin
    Department of Psychiatry, University of Wisconsin, Madison, Wisconsin 53719, USA
    J Neurosci 24:5506-15. 2004
    ..These findings suggest that in primates, the CeA is involved in mediating fear- and anxiety-related behavioral and pituitary-adrenal responses as well as in modulating brain CRF activity...
  78. pmc Brain function and gaze fixation during facial-emotion processing in fragile X and autism
    Kim M Dalton
    Waisman Center, University of Wisconsin, Madison, Wisconsin 53705 2208, USA
    Autism Res 1:231-9. 2008
    ....
  79. ncbi request reprint Topological characterization of signal in brain images using min-max diagrams
    Moo K Chung
    Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI 53706, USA
    Med Image Comput Comput Assist Interv 12:158-66. 2009
    ..As an application, we have used this method to characterize cortical thickness measures along brain surfaces in classifying autistic subjects. Our promising experimental results provide evidence of the power of this representation...
  80. ncbi request reprint Less white matter concentration in autism: 2D voxel-based morphometry
    Moo K Chung
    Department of Statistics, University of Wisconsin Madison, Madison, WI 53706, USA
    Neuroimage 23:242-51. 2004
    ..Further, it is shown that the less white matter concentration in the corpus callosum in autism is due to hypoplasia rather than atrophy...
  81. pmc Cosmetic use of botulinum toxin-a affects processing of emotional language
    David A Havas
    Department of Psychology, University of Wisconsin Madison, 1202 W Johnson St, Madison, WI 53706 1611, USA
    Psychol Sci 21:895-900. 2010
    ..We account for the role of facial feedback in language processing by considering neurophysiological mechanisms and reinforcement-learning theory...
  82. ncbi request reprint Disambiguating the components of emotion regulation
    H H Goldsmith
    Department of Psychology, University of Wisconsin Madison, WI 53706, USA
    Child Dev 75:361-5. 2004
    ..Individual differences in emotion regulation and a focus on the context of emotion experience and expression provide additional tools to study emotion regulation, and its development, from a biobehavioral perspective...
  83. ncbi request reprint Depression: perspectives from affective neuroscience
    Richard J Davidson
    Laboratory for Affective Neuroscience and W M Keck Laboratory for Functional Brain Imaging and Behavior, University of Wisconsin Madison, Madison, Wisconsin 53705 2280, USA
    Annu Rev Psychol 53:545-74. 2002
    ....
  84. ncbi request reprint Affective neuroscience and psychophysiology: toward a synthesis
    Richard J Davidson
    Laboratory for Affective Neuroscience, University of Wisconsin, Madison, Wisconsin 53706, USA
    Psychophysiology 40:655-65. 2003
    ..The implications of this body of work for a broader conception of psychophysiology and for training the next generation of psychophysiologists are considered in the conclusion...
  85. ncbi request reprint Seven sins in the study of emotion: correctives from affective neuroscience
    Richard J Davidson
    Laboratory for Affective Neuroscience, University of Wisconsin Madison, 1202 West Johnson Street, Madison, WI 53706, USA
    Brain Cogn 52:129-32. 2003
    ..The articles in this Special Issue underscore the vitality of research in affective neuroscience and illustrate how some of these sins can be addressed and rectified using concepts and methods from affective neuroscience...
  86. ncbi request reprint The neural substrates of affective processing in depressed patients treated with venlafaxine
    Richard J Davidson
    Department of Psychology, University of Wisconsin, 1202 West Johnson St, Madison, WI 53706, USA
    Am J Psychiatry 160:64-75. 2003
    ..Relations between baseline neural activation and response to treatment were also evaluated...
  87. ncbi request reprint Normative emotion-modulated startle response in individuals at risk for schizophrenia-spectrum disorders
    Diane C Gooding
    University of Wisconsin Madison, Department of Psychology and Psychiatry, 1202 W Johnson Street, Madison, WI 53706 1696, USA
    Schizophr Res 57:109-20. 2002
    ..These findings suggest that the affective deficits reported by socially anhedonic individuals are not global in nature...
  88. ncbi request reprint Stability of amygdala BOLD response to fearful faces over multiple scan sessions
    Tom Johnstone
    W M Keck Laboratory for Functional Brain Imaging and Behavior, University of Wisconsin, WI 53705, USA
    Neuroimage 25:1112-23. 2005
    ..Future studies might manipulate the experimental design to either amplify or attenuate this variability, according to the goals of the research...
  89. ncbi request reprint Darwin and the neural bases of emotion and affective style
    Richard J Davidson
    W M Keck Laboratory for Functional Brain Imaging and Behavior, University of Wisconsin, Madison, Wisconsin 53706, USA
    Ann N Y Acad Sci 1000:316-36. 2003
    ..Honoring brain circuitry in parsing the domain of affects will result in distinctions and differentiations that are not currently incorporated in traditional classification schemes...
  90. pmc Creating physical 3D stereolithograph models of brain and skull
    Daniel J Kelley
    Waisman Laboratory for Brain Imaging and Behavior, Waisman Center, Madison, Wisconsin, United States of America
    PLoS ONE 2:e1119. 2007
    ..Compared to 2D images, VR and stereolithograph models provide an extra dimension that enhances both the quality of visual information and utility of surface visualization in neuroscience and medicine...
  91. pmc An imaging roadmap for biology education: from nanoparticles to whole organisms
    Daniel J Kelley
    Waisman Laboratory for Brain Imaging and Behavior, Waisman Center, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA
    CBE Life Sci Educ 7:202-9. 2008
    ..The NIH Roadmap provides a useful context to educate students about the multidisciplinary imaging continuum...
  92. doi request reprint Tensor-based cortical surface morphometry via weighted spherical harmonic representation
    Moo K Chung
    Department of Biostatistics and Medical Informatics, and the Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin, Madison, WI 53706, USA
    IEEE Trans Med Imaging 27:1143-51. 2008
    ..As an illustration, the methodology has been applied in the problem of detecting abnormal cortical regions in the group of high functioning autistic subjects...
  93. ncbi request reprint Emotion as motion: asymmetries in approach and avoidant actions
    Jeffrey S Maxwell
    University of Wisconsin Madison, WI 53706, USA
    Psychol Sci 18:1113-9. 2007
    ..Collectively, these findings have direct implications for models of embodied emotional and perceptual processing, as well as for investigations of individual differences in emotional disposition...
  94. pmc Affective neural circuitry and mind-body influences in asthma
    Melissa A Rosenkranz
    University of Wisconsin Madison, Waisman Laboratory for Brain Imaging and Behavior, 1500 Highland Ave, Madison, WI 53705, USA
    Neuroimage 47:972-80. 2009
    ....
  95. pmc An fMRI investigation of the impact of withdrawal on regional brain activity during nicotine anticipation
    Rebecca Gloria
    Department of Psychology, University of Wisconsin, Madison, Wisconsin 53706, USA
    Psychophysiology 46:681-93. 2009
    ..These results suggest that withdrawal and nicotine anticipation produce (1) different motor preparatory and inhibitory response processing and (2) different craving related processing...
  96. pmc The privileged status of emotion in the brain
    Richard J Davidson
    Laboratory for Affective Neuroscience, University of Wisconsin, Madison, WI 53706, USA
    Proc Natl Acad Sci U S A 101:11915-6. 2004
  97. pmc Long-term meditators self-induce high-amplitude gamma synchrony during mental practice
    Antoine Lutz
    W M Keck Laboratory for Functional Brain Imaging and Behavior, Waisman Center, and Laboratory for Affective Neuroscience, Department of Psychology, University of Wisconsin, 1500 Highland Avenue, Madison, WI 53705, USA
    Proc Natl Acad Sci U S A 101:16369-73. 2004
    ..These data suggest that mental training involves temporal integrative mechanisms and may induce short-term and long-term neural changes...
  98. ncbi request reprint Cortical thickness analysis in autism with heat kernel smoothing
    Moo K Chung
    Department of Statistics, University of Wisconsin, 1210 West Dayton Street, Madison, WI 53706, USA
    Neuroimage 25:1256-65. 2005
    ..As an illustration, we apply our methods in detecting the regions of abnormal cortical thickness in 16 high functioning autistic children via random field based multiple comparison correction that utilizes the new smoothing technique...
  99. ncbi request reprint Startle potentiation in aversive anticipation: evidence for state but not trait effects
    Jack B Nitschke
    Department of Psychology, University of Wisconsin, Madison 53706 1696, USA
    Psychophysiology 39:254-8. 2002
    ..These data suggest that the aversive nature of stimuli contribute to the potentiation of startle above and beyond the effects of emotional arousal, which may be a universal phenomenon not modulated by individual differences...
  100. ncbi request reprint Affective judgments of faces modulate early activity (approximately 160 ms) within the fusiform gyri
    Diegon A Pizzagalli
    Department of Psychology, University of Wisconsin, Madison 53705, USA
    Neuroimage 16:663-77. 2002
    ..Increased FG activation for liked faces may thus be interpreted as reflecting enhanced attention due to their saliency...
  101. pmc A functional magnetic resonance imaging predictor of treatment response to venlafaxine in generalized anxiety disorder
    Paul J Whalen
    Department of Psychological and Brain Sciences, Dartmouth College, Hanover, New Hampshire 03755, USA
    Biol Psychiatry 63:858-63. 2008
    ..Here, we sought to determine whether pretreatment amygdala and rostral ACC (rACC) reactivity to facial expressions could predict treatment outcomes in patients with generalized anxiety disorder (GAD)...