PHILIP DAVIDSON

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. pmc Fish consumption and prenatal methylmercury exposure: cognitive and behavioral outcomes in the main cohort at 17 years from the Seychelles child development study
    Philip W Davidson
    Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Neurotoxicology 32:711-7. 2011
  2. pmc Neurodevelopmental effects of maternal nutritional status and exposure to methylmercury from eating fish during pregnancy
    Philip W Davidson
    University of Rochester School of Medicine and Dentistry, Box 671, URMC, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Neurotoxicology 29:767-75. 2008
  3. pmc Association between prenatal exposure to methylmercury and visuospatial ability at 10.7 years in the seychelles child development study
    Philip W Davidson
    University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Neurotoxicology 29:453-9. 2008
  4. ncbi request reprint Association between prenatal exposure to methylmercury and developmental outcomes in Seychellois children: effect modification by social and environmental factors
    P W Davidson
    Department of Pediatrics, University of Rochester School of Medicine and Dentistry, New York 14642, USA
    Neurotoxicology 20:833-41. 1999
  5. ncbi request reprint Methylmercury and neurodevelopment: longitudinal analysis of the Seychelles child development cohort
    Philip W Davidson
    The Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, New York, 14642, USA
    Neurotoxicol Teratol 28:529-35. 2006
  6. ncbi request reprint Development and validation of a test battery to assess subtle neurodevelopmental differences in children
    Philip W Davidson
    University of Rochester School of Medicine, Rochester, NY, USA
    Neurotoxicology 27:951-69. 2006
  7. ncbi request reprint Prenatal methyl mercury exposure from fish consumption and child development: a review of evidence and perspectives from the Seychelles Child Development Study
    Philip W Davidson
    University of Rochester School of Medicine and Dentistry, USA
    Neurotoxicology 27:1106-9. 2006
  8. ncbi request reprint Evaluation of techniques for assessing neurobehavioral development in children
    P W Davidson
    Department of Pediatrics, University of Rochester School of Medicine and Dentistry, NY 14642, USA
    Neurotoxicology 21:957-72. 2000
  9. ncbi request reprint Prenatal exposure to methylmercury and child development: influence of social factors
    Philip W Davidson
    Strong Center for Developmental Disabilities, Department of Pediatrics, Box 671, School of Medicine and Dentistry, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Neurotoxicol Teratol 26:553-9. 2004
  10. ncbi request reprint Mercury exposure and child development outcomes
    Philip W Davidson
    Strong Center for Developmental Disabilities, Golisano Children s Hospital at Strong, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Pediatrics 113:1023-9. 2004

Detail Information

Publications24

  1. pmc Fish consumption and prenatal methylmercury exposure: cognitive and behavioral outcomes in the main cohort at 17 years from the Seychelles child development study
    Philip W Davidson
    Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Neurotoxicology 32:711-7. 2011
    ..For some endpoints we found performance improved with increasing prenatal exposure to MeHg. Follow up studies indicate this association is related to the beneficial nutrients present in fish...
  2. pmc Neurodevelopmental effects of maternal nutritional status and exposure to methylmercury from eating fish during pregnancy
    Philip W Davidson
    University of Rochester School of Medicine and Dentistry, Box 671, URMC, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Neurotoxicology 29:767-75. 2008
    ..These findings suggest a possible confounding role of maternal nutrition in studies examining associations between prenatal MeHg exposures and developmental outcomes in children...
  3. pmc Association between prenatal exposure to methylmercury and visuospatial ability at 10.7 years in the seychelles child development study
    Philip W Davidson
    University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Neurotoxicology 29:453-9. 2008
    ..04), but not when the single outlier was removed (p=0.07). In a population whose exposure to MeHg is from fish consumption, we continue to find no consistent adverse association between MeHg and visual motor coordination...
  4. ncbi request reprint Association between prenatal exposure to methylmercury and developmental outcomes in Seychellois children: effect modification by social and environmental factors
    P W Davidson
    Department of Pediatrics, University of Rochester School of Medicine and Dentistry, New York 14642, USA
    Neurotoxicology 20:833-41. 1999
    ..We performed secondary analyses to determine if effect modification (EM) from social and environmental factors was affecting associations between MeHg and outcomes...
  5. ncbi request reprint Methylmercury and neurodevelopment: longitudinal analysis of the Seychelles child development cohort
    Philip W Davidson
    The Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, New York, 14642, USA
    Neurotoxicol Teratol 28:529-35. 2006
    ..These findings suggest that the associations observed between MeHg and developmental outcomes may vary with developmental stage...
  6. ncbi request reprint Development and validation of a test battery to assess subtle neurodevelopmental differences in children
    Philip W Davidson
    University of Rochester School of Medicine, Rochester, NY, USA
    Neurotoxicology 27:951-69. 2006
    ..Further studies are needed to confirm the capability of the RTB to detect subtle changes associated with neurotoxic exposures...
  7. ncbi request reprint Prenatal methyl mercury exposure from fish consumption and child development: a review of evidence and perspectives from the Seychelles Child Development Study
    Philip W Davidson
    University of Rochester School of Medicine and Dentistry, USA
    Neurotoxicology 27:1106-9. 2006
    ..This suggests that the association between prenatal exposure and child development may be more complex than originally believed. This paper reviews the SCDS main cohort study results and presents our current interpretations...
  8. ncbi request reprint Evaluation of techniques for assessing neurobehavioral development in children
    P W Davidson
    Department of Pediatrics, University of Rochester School of Medicine and Dentistry, NY 14642, USA
    Neurotoxicology 21:957-72. 2000
    ..Our findings suggest a number of tests and procedures with the potential for inclusion in test batteries aimed at the exploration of adverse neurodevelopmental effects...
  9. ncbi request reprint Prenatal exposure to methylmercury and child development: influence of social factors
    Philip W Davidson
    Strong Center for Developmental Disabilities, Department of Pediatrics, Box 671, School of Medicine and Dentistry, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Neurotoxicol Teratol 26:553-9. 2004
    ..We performed a similar analysis of the 66-month evaluations to determine if the modifying influences of social and environmental factors were consistent with those previously observed...
  10. ncbi request reprint Mercury exposure and child development outcomes
    Philip W Davidson
    Strong Center for Developmental Disabilities, Golisano Children s Hospital at Strong, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Pediatrics 113:1023-9. 2004
    ..Our intent is to focus the debate about mercury on 1) additional research that should be sought and 2) defining the principal issues that public policy makers face...
  11. ncbi request reprint Associations between behavior disorders and health status among older adults with intellectual disability
    P W Davidson
    University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Aging Ment Health 7:424-30. 2003
    ..Moreover, behavioral disorders may be sentinels for occult medical morbidity, which in turn may be responsive to intervention...
  12. pmc Fish consumption, mercury exposure, and their associations with scholastic achievement in the Seychelles Child Development Study
    Philip W Davidson
    University of Rochester, School of Medicine and Dentistry, Department of Pediatrics, Rochester, NY 14642, USA
    Neurotoxicology 31:439-47. 2010
    ..The adverse association of educational measures with postnatal exposure in males is intriguing, but will need to be confirmed by further studies examining factors that influence scholastic achievement...
  13. pmc Varying coefficient function models to explore interactions between maternal nutritional status and prenatal methylmercury toxicity in the Seychelles Child Development Nutrition Study
    Miranda L Lynch
    Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Environ Res 111:75-80. 2011
    ..The results encourage more emphasis on a holistic view of the risks and benefits of fish consumption as it relates to infant development...
  14. pmc Postnatal exposure to methyl mercury from fish consumption: a review and new data from the Seychelles Child Development Study
    Gary J Myers
    University of Rochester School of Medicine and Dentistry, Department of Neurology, Rochester, NY, United States
    Neurotoxicology 30:338-49. 2009
    ....
  15. pmc Bayesian models for multiple outcomes nested in domains
    Sally W Thurston
    University of Rochester, Department of Biostatistics and Computational Biology, 601 Elmwood Avenue, Box 630, Rochester, New York 14642, USA
    Biometrics 65:1078-86. 2009
    ..Simulation studies examine the model performance under alternative scenarios. Our results demonstrate that a sizeable increase in power is possible...
  16. pmc Interpreting epidemiological evidence in the presence of multiple endpoints: an alternative analytic approach using the 9-year follow-up of the Seychelles child development study
    Edwin van Wijngaarden
    Department of Community and Preventive Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, 14642, USA
    Int Arch Occup Environ Health 82:1031-41. 2009
    ..These studies evaluate a large number of developmental tests. We propose an alternative analysis strategy that reduces the number of comparisons tested in these studies...
  17. ncbi request reprint Exploring nonlinear association between prenatal methylmercury exposure from fish consumption and child development: evaluation of the Seychelles Child Development Study nine-year data using semiparametric additive models
    Li Shan Huang
    Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Environ Res 97:100-8. 2005
    ..We conclude that this reanalysis supports the primary linear analysis, showing little evidence for a prenatal adverse effect...
  18. ncbi request reprint Prenatal methylmercury exposure from ocean fish consumption in the Seychelles child development study
    Gary J Myers
    Department of Neurology, National Institute for Child Health and Development, National Institutes of Health, Department of Health and Human Services, Bethesda, USA
    Lancet 361:1686-92. 2003
    ..The most common form of prenatal exposure is maternal fish consumption, but whether such exposure harms the fetus is unknown. We aimed to identify adverse neurodevelopmental effects in a fish-consuming population...
  19. ncbi request reprint Nutrient and methyl mercury exposure from consuming fish
    Gary J Myers
    Department of Neurology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    J Nutr 137:2805-8. 2007
    ..Preliminary findings from this study suggest that the beneficial influence of nutrients from fish may counter any adverse effects of MeHg on the developing nervous system...
  20. pmc Is susceptibility to prenatal methylmercury exposure from fish consumption non-homogeneous? Tree-structured analysis for the Seychelles Child Development Study
    Li Shan Huang
    Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Neurotoxicology 28:1237-44. 2007
    ..The regression tree results support previous analyses of outcomes in this cohort. However, this analysis raises the intriguing possibility that an effect may be non-homogeneous among children with different backgrounds and IQ levels...
  21. pmc Does prenatal methylmercury exposure from fish consumption affect blood pressure in childhood?
    Sally W Thurston
    Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, United States
    Neurotoxicology 28:924-30. 2007
    ..We examined this relationship in the Seychelles Islands to determine if it was present in a society exposed primarily to MeHg from consuming ocean fish...
  22. ncbi request reprint Using measurement error models to assess effects of prenatal and postnatal methylmercury exposure in the Seychelles Child Development Study
    Li Shan Huang
    Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Box 630, Rochester, NY 14642, USA
    Environ Res 93:115-22. 2003
    ..Our reanalysis indicated that adjustment for measurement errors in explanatory variables had no appreciable effect on the original results...
  23. ncbi request reprint Benchmark concentrations for methyl mercury obtained from the 9-year follow-up of the Seychelles Child Development Study
    Edwin van Wijngaarden
    Department of Community and Preventive Medicine, 601 Elmwood Avenue, Box 644, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Neurotoxicology 27:702-9. 2006
    ..These estimates are somewhat lower than those obtained after 66 months of follow-up. The Seychelles Child Development Study continues to provide a firm scientific basis for the derivation of safe levels of MeHg consumption...
  24. ncbi request reprint Maternal fish consumption benefits children's development
    Gary J Myers
    Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Lancet 369:537-8. 2007

Research Grants14

  1. Conference on Intellectual Disability, Aging and Health
    PHILIP DAVIDSON; Fiscal Year: 2002
    ..This area will lead to a report of recommendations for the establishment of practice guidelines for medical care jointly issued by the AAMR and the AMA. ..
  2. Methyl Mercury Effect on Adolescent Development Renewal
    Philip W Davidson; Fiscal Year: 2010
    ....
  3. Methyl Mercury Effects on Adolescent Development
    PHILIP DAVIDSON; Fiscal Year: 2009
    ..abstract_text> ..
  4. Factors Modifying the Toxicity of Methylmercury in a Fish-Eating Population
    Philip W Davidson; Fiscal Year: 2010
    ..The results should have immediate and important public health implications not only for agencies that advise the public about fish consumption, but also for public health policies regarding nutrient intake during pregnancy. ..
  5. Methyl Mercury Effects on Adolescent Development
    PHILIP DAVIDSON; Fiscal Year: 2009
    ..abstract_text> ..
  6. Methyl Mercury Effects on Adolescent Development
    PHILIP DAVIDSON; Fiscal Year: 2007
    ..This study will inform public health policy concerning the balance of risks and benefits of consuming fish during pregnancy with respect to cardiovascular health and cognitive information processing. ..
  7. Factors Modifying the Toxicity of Methylmercury in a Fish-Eating Population
    Philip W Davidson; Fiscal Year: 2011
    ..The results should have immediate and important public health implications not only for agencies that advise the public about fish consumption, but also for public health policies regarding nutrient intake during pregnancy. ..