Mita Das

Summary

Affiliation: University of Colorado Health Sciences Center
Country: USA

Publications

  1. ncbi Hypoxia-induced proliferative response of vascular adventitial fibroblasts is dependent on g protein-mediated activation of mitogen-activated protein kinases
    M Das
    Cardiovascular Pulmonary and Developmental Lung Biology Research Labs and the Department of Renal Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Biol Chem 276:15631-40. 2001
  2. ncbi Selective expansion of fibroblast subpopulations from pulmonary artery adventitia in response to hypoxia
    M Das
    Cardiovascular Pulmonary and Developmental Lung Biology Research Laboratories, University of Colorado Health Sciences Center, Denver 80262, USA
    Am J Physiol Lung Cell Mol Physiol 282:L976-86. 2002
  3. ncbi Hypoxia exposure induces the emergence of fibroblasts lacking replication repressor signals of PKCzeta in the pulmonary artery adventitia
    Mita Das
    Department of Pediatrics, B131, University of Colorado Denver, School of Medicine, 4200 E 9th Avenue, Denver, CO 80262, USA
    Cardiovasc Res 78:440-8. 2008
  4. ncbi Protein kinase Czeta attenuates hypoxia-induced proliferation of fibroblasts by regulating MAP kinase phosphatase-1 expression
    Megan D Short
    Developmental Lung Biology Research Laboratory, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Mol Biol Cell 17:1995-2008. 2006
  5. ncbi Hypoxia induces differentiation of pulmonary artery adventitial fibroblasts into myofibroblasts
    Megan Short
    Department of Pediatrics, Developmental Lung Biology Research Laboratories, University of Colorado Health Sciences Center, 4200 E. 9th Ave, Denver, CO 80262, USA
    Am J Physiol Cell Physiol 286:C416-25. 2004
  6. ncbi Hypoxia-induced alterations in protein kinase C zeta signaling result in augmented fibroblast proliferation
    Megan Short
    Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Chest 128:582S. 2005
  7. ncbi Role of the adventitia in pulmonary vascular remodeling
    Kurt R Stenmark
    Division of Pediatric Critical Care, University of Colorado at Denver and Health Sciences Center, Denver, Colorado, USA
    Physiology (Bethesda) 21:134-45. 2006
  8. ncbi Hypoxic activation of adventitial fibroblasts: role in vascular remodeling
    Kurt R Stenmark
    Developmental Lung Biology Research Laboratory, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Chest 122:326S-334S. 2002
  9. ncbi Mitogen-activated protein kinase phosphatase-1 is a key regulator of hypoxia-induced vascular endothelial growth factor expression and vessel density in lung
    Kristin M Shields
    Department of Pediatrics, University of Colorado Denver, Aurora, Colorado, USA
    Am J Pathol 178:98-109. 2011
  10. ncbi Neurotransplantation of stem cells genetically modified to express human dopamine transporter reduces alcohol consumption
    Tom N Grammatopoulos
    Department of Medicine, University of Colorado Denver, 12800 East 19th Avenue, Aurora, CO 80045, USA
    Stem Cell Res Ther 1:36. 2010

Collaborators

Detail Information

Publications11

  1. ncbi Hypoxia-induced proliferative response of vascular adventitial fibroblasts is dependent on g protein-mediated activation of mitogen-activated protein kinases
    M Das
    Cardiovascular Pulmonary and Developmental Lung Biology Research Labs and the Department of Renal Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Biol Chem 276:15631-40. 2001
    ....
  2. ncbi Selective expansion of fibroblast subpopulations from pulmonary artery adventitia in response to hypoxia
    M Das
    Cardiovascular Pulmonary and Developmental Lung Biology Research Laboratories, University of Colorado Health Sciences Center, Denver 80262, USA
    Am J Physiol Lung Cell Mol Physiol 282:L976-86. 2002
    ..We conclude that the bovine PA adventitia comprises numerous phenotypically and biochemically distinct fibroblast subpopulations and that select subpopulations expand in response to chronic hypoxia...
  3. ncbi Hypoxia exposure induces the emergence of fibroblasts lacking replication repressor signals of PKCzeta in the pulmonary artery adventitia
    Mita Das
    Department of Pediatrics, B131, University of Colorado Denver, School of Medicine, 4200 E 9th Avenue, Denver, CO 80262, USA
    Cardiovasc Res 78:440-8. 2008
    ....
  4. ncbi Protein kinase Czeta attenuates hypoxia-induced proliferation of fibroblasts by regulating MAP kinase phosphatase-1 expression
    Megan D Short
    Developmental Lung Biology Research Laboratory, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Mol Biol Cell 17:1995-2008. 2006
    ....
  5. ncbi Hypoxia induces differentiation of pulmonary artery adventitial fibroblasts into myofibroblasts
    Megan Short
    Department of Pediatrics, Developmental Lung Biology Research Laboratories, University of Colorado Health Sciences Center, 4200 E. 9th Ave, Denver, CO 80262, USA
    Am J Physiol Cell Physiol 286:C416-25. 2004
    ....
  6. ncbi Hypoxia-induced alterations in protein kinase C zeta signaling result in augmented fibroblast proliferation
    Megan Short
    Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Chest 128:582S. 2005
  7. ncbi Role of the adventitia in pulmonary vascular remodeling
    Kurt R Stenmark
    Division of Pediatric Critical Care, University of Colorado at Denver and Health Sciences Center, Denver, Colorado, USA
    Physiology (Bethesda) 21:134-45. 2006
    ..The purpose of this review is to present the current evidence demonstrating that the adventitial fibroblast acts as a key regulator of pulmonary vascular function and structure from the "outside-in."..
  8. ncbi Hypoxic activation of adventitial fibroblasts: role in vascular remodeling
    Kurt R Stenmark
    Developmental Lung Biology Research Laboratory, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Chest 122:326S-334S. 2002
    ....
  9. ncbi Mitogen-activated protein kinase phosphatase-1 is a key regulator of hypoxia-induced vascular endothelial growth factor expression and vessel density in lung
    Kristin M Shields
    Department of Pediatrics, University of Colorado Denver, Aurora, Colorado, USA
    Am J Pathol 178:98-109. 2011
    ..Therefore, our data strongly suggest that MKP-1 might be the key regulator of vascular densities through the regulation of VEGF levels in hypoxic lung...
  10. ncbi Neurotransplantation of stem cells genetically modified to express human dopamine transporter reduces alcohol consumption
    Tom N Grammatopoulos
    Department of Medicine, University of Colorado Denver, 12800 East 19th Avenue, Aurora, CO 80045, USA
    Stem Cell Res Ther 1:36. 2010
    ..We reasoned that reducing extracellular DA levels, by engrafting into NAC DA-sequestering stem cells expressing hDAT, would alter alcohol intake...
  11. ncbi Dopamine selectively sensitizes dopaminergic neurons to rotenone-induced apoptosis
    Ferogh A Ahmadi
    Division of Clinical Pharmacology and Toxicology, Department of Medicine, University of Colorado at Denver and Health Sciences Center, Denver, CO 80262, USA
    Neurochem Res 33:886-901. 2008
    ..Our results demonstrate that an inhibitor of mitochondrial complex I and increased cytosolic DA may cooperatively lead to conditions of elevated oxidative stress and thereby promote selective demise of dopaminergic neurons...