David A D'Argenio

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. pmc Autolysis and autoaggregation in Pseudomonas aeruginosa colony morphology mutants
    David A D'Argenio
    Department of Genome Sciences, University of Washington, Seattle, Washington 98195 7730, USA
    J Bacteriol 184:6481-9. 2002
  2. pmc Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients
    David A D'Argenio
    Department of Microbiology, University of Washington, Seattle, WA, USA
    Mol Microbiol 64:512-33. 2007
  3. ncbi request reprint Aminoglycoside antibiotics induce bacterial biofilm formation
    Lucas R Hoffman
    Department of Pediatrics, University of Washington, Seattle, Washington 98195, USA
    Nature 436:1171-5. 2005
  4. pmc Large-insert genome analysis technology detects structural variation in Pseudomonas aeruginosa clinical strains from cystic fibrosis patients
    Hillary S Hayden
    Genome Center, University of Washington, Seattle, WA 98195, USA
    Genomics 91:530-7. 2008
  5. pmc Selection for Staphylococcus aureus small-colony variants due to growth in the presence of Pseudomonas aeruginosa
    Lucas R Hoffman
    Department of Pediatrics, University of Washington, Seattle, WA 98195, USA
    Proc Natl Acad Sci U S A 103:19890-5. 2006
  6. ncbi request reprint Cyclic di-GMP as a bacterial second messenger
    David A D'Argenio
    Department of Microbiology, University of Washington, Seattle, WA 98195, USA
    Microbiology 150:2497-502. 2004
  7. pmc Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains
    Laurence Rohmer
    Department of Genome Sciences, University of Washington, Campus Box 357710, 1705 NE Pacific Street Seattle, Washington 98195, USA
    Genome Biol 8:R102. 2007
  8. pmc Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients
    Eric E Smith
    Genome Center, Program in Molecular and Cellular Biology, University of Washington, Seattle, WA 98195, USA
    Proc Natl Acad Sci U S A 103:8487-92. 2006

Detail Information

Publications8

  1. pmc Autolysis and autoaggregation in Pseudomonas aeruginosa colony morphology mutants
    David A D'Argenio
    Department of Genome Sciences, University of Washington, Seattle, Washington 98195 7730, USA
    J Bacteriol 184:6481-9. 2002
    ..The fact that PQS levels correlated with autolysis suggests a fine balance in natural populations of P. aeruginosa between survival of the many and persistence of the few...
  2. pmc Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients
    David A D'Argenio
    Department of Microbiology, University of Washington, Seattle, WA, USA
    Mol Microbiol 64:512-33. 2007
    ..Loss of LasR function may represent a marker of an early stage in chronic infection of the CF airway with clinical implications for antibiotic resistance and disease progression...
  3. ncbi request reprint Aminoglycoside antibiotics induce bacterial biofilm formation
    Lucas R Hoffman
    Department of Pediatrics, University of Washington, Seattle, Washington 98195, USA
    Nature 436:1171-5. 2005
    ..Our results demonstrate that biofilm formation can be a specific, defensive reaction to the presence of antibiotics, and indicate that the molecular basis of this response includes alterations in the level of c-di-GMP...
  4. pmc Large-insert genome analysis technology detects structural variation in Pseudomonas aeruginosa clinical strains from cystic fibrosis patients
    Hillary S Hayden
    Genome Center, University of Washington, Seattle, WA 98195, USA
    Genomics 91:530-7. 2008
    ..aeruginosa and validates a technology that complements emerging, short-read sequencing methods that are better suited to characterizing single-nucleotide polymorphisms than structural variation...
  5. pmc Selection for Staphylococcus aureus small-colony variants due to growth in the presence of Pseudomonas aeruginosa
    Lucas R Hoffman
    Department of Pediatrics, University of Washington, Seattle, WA 98195, USA
    Proc Natl Acad Sci U S A 103:19890-5. 2006
    ....
  6. ncbi request reprint Cyclic di-GMP as a bacterial second messenger
    David A D'Argenio
    Department of Microbiology, University of Washington, Seattle, WA 98195, USA
    Microbiology 150:2497-502. 2004
    ..Genetic evidence suggests that the GGDEF domain acts as a nucleotide cyclase for c-di-GMP synthesis while the EAL domain is a good candidate for the opposing activity, a phosphodiesterase for c-di-GMP degradation...
  7. pmc Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains
    Laurence Rohmer
    Department of Genome Sciences, University of Washington, Campus Box 357710, 1705 NE Pacific Street Seattle, Washington 98195, USA
    Genome Biol 8:R102. 2007
    ....
  8. pmc Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients
    Eric E Smith
    Genome Center, Program in Molecular and Cellular Biology, University of Washington, Seattle, WA 98195, USA
    Proc Natl Acad Sci U S A 103:8487-92. 2006
    ..aeruginosa strains present in advanced CF infections differ systematically from those of "wild-type" P. aeruginosa and that these differences may offer new opportunities for treatment of this chronic disease...