Research Topics
Species | Mirella DaprettoSummaryAffiliation: University of California Country: USA Publications
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Publications
Form and content: dissociating syntax and semantics in sentence comprehensionM Dapretto
Ahmanson Lovelace Brain Mapping Center, Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles 90095, USA
Neuron 24:427-32. 1999....
The development of word retrieval abilities in the second year and its relation to early vocabulary growthM Dapretto
Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, Ahmanson Lovelace Brain Mapping Center, Los Angeles, CA 90095, USA
Child Dev 71:635-48. 2000..Naming errors during a naturalistic book-reading session peaked in children whose productive vocabularies had recently begun to expand, further suggesting that word retrieval processes undergo significant changes at this time...
A functional magnetic resonance imaging study of discourse coherence in typically developing childrenMirella Dapretto
Ahmanson Lovelace Brain Mapping Center, University of California at Los Angeles, 90095, USA
Neuroreport 16:1661-5. 2005....
Understanding emotions in others: mirror neuron dysfunction in children with autism spectrum disordersMirella Dapretto
Ahmanson Lovelace Brain Mapping Center, Semel Institute for Neuroscience and Human Behavior, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California Los Angeles, 90095, USA
Nat Neurosci 9:28-30. 2006..Notably, activity in this area was inversely related to symptom severity in the social domain, suggesting that a dysfunctional 'mirror neuron system' may underlie the social deficits observed in autism...
Frontal contributions to face processing differences in autism: evidence from fMRI of inverted face processingSusan Y Bookheimer
Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095, USA
J Int Neuropsychol Soc 14:922-32. 2008..Our results are consistent with other recent studies implicating frontal and limbic dysfunction during face processing in autism...
No neural evidence of statistical learning during exposure to artificial languages in children with autism spectrum disordersAshley A Scott-Van Zeeland
Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California, USA
Biol Psychiatry 68:345-51. 2010..Importantly, early word segmentation skills have been shown to predict later language development in typically developing (TD) children...
Mirroring others' emotions relates to empathy and interpersonal competence in childrenJennifer H Pfeifer
Ahmanson Lovelace Brain Mapping Center, Jane and Terry Semel Institute for Neuroscience and Human Behavior at UCLA, Los Angeles, CA 90095 7085, USA
Neuroimage 39:2076-85. 2008..These findings suggest that simulation mechanisms and the MNS may indeed be relevant to social functioning in everyday life during typical human development...
Reading affect in the face and voice: neural correlates of interpreting communicative intent in children and adolescents with autism spectrum disordersA Ting Wang
Department of Psychiatry, University of California, Los Angeles, USA
Arch Gen Psychiatry 64:698-708. 2007..However, there is also evidence that activity in key regions can be increased if task demands allow for explicit processing of emotion...
Neural basis of irony comprehension in children with autism: the role of prosody and contextA Ting Wang
Department of Psychology, University of California, Los Angeles, CA, USA
Brain 129:932-43. 2006....
Age and experience shape developmental changes in the neural basis of language-related learningKristin McNealy
Ahmanson Lovelace Brain Mapping Center, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA 90095, USA
Dev Sci 14:1261-82. 2011....
Language network dysfunction as a predictor of outcome in youth at clinical high risk for psychosisFred W Sabb
Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Box 956968, Rm 2265, 300 Medical Plaza, Los Angeles, CA 90095 6968, USA
Schizophr Res 116:173-83. 2010..Yet, no study to date has investigated underlying neural networks associated with discourse processing in adolescents at clinical high risk (CHR) for developing psychosis(1)...
Developmental changes in the neural basis of interpreting communicative intentA Ting Wang
Department of Psychology, University of California, Los Angeles, CA 90095, USA
Soc Cogn Affect Neurosci 1:107-21. 2006..This study is the first to examine developmental changes in the neural circuitry underlying natural language pragmatics...
Atypical neural networks for social orienting in autism spectrum disordersDeanna J Greene
Department of Psychology, University of California, Los Angeles, CA 90095 1563, USA
Neuroimage 56:354-62. 2011....
Neural correlates of social exclusion during adolescence: understanding the distress of peer rejectionCarrie L Masten
Department of Psychology, University of California, Los Angeles, Los Angeles, CA 90095 1563, USA
Soc Cogn Affect Neurosci 4:143-57. 2009....
Autism-associated promoter variant in MET impacts functional and structural brain networksJeffrey D Rudie
Ahmanson Lovelace Brain Mapping Center, University of California, Los Angeles, Los Angeles, CA 90095 7085, USA
Neuron 75:904-15. 2012..Notably, these effects were more pronounced in individuals with ASD. These findings highlight how genetic stratification may reduce heterogeneity and help elucidate the biological basis of complex neuropsychiatric disorders such as ASD...
Neural correlates of facial affect processing in children and adolescents with autism spectrum disorderA Ting Wang
Department of Psychology, UCLA, Los Angeles, CA, USA
J Am Acad Child Adolesc Psychiatry 43:481-90. 2004..High-functioning individuals with ASD may be relatively unimpaired in the cognitive assessment of basic emotions, yet still show differences in the automatic processing of facial expressions...
Witnessing peer rejection during early adolescence: neural correlates of empathy for experiences of social exclusionCarrie L Masten
Department of Psychology, University of California, 1285 Franz Hall, Box 951563, Los Angeles, CA 90095 1563, USA
Soc Neurosci 5:496-507. 2010..Overall findings suggest that when early adolescents witness social exclusion in their daily lives, some may actually 'feel the pain' of the victims and act more prosocially toward them as a result...
Subgenual anterior cingulate responses to peer rejection: a marker of adolescents' risk for depressionCarrie L Masten
Department of Psychology, University of California, Los Angeles, 1285 Franz Hall, Box 951563, Los Angeles, CA 90095 1563, USA
Dev Psychopathol 23:283-92. 2011....
The mirror neuron system and the consequences of its dysfunctionMarco Iacoboni
Ahmanson Lovelace Brain Mapping Center, Department of Psychiatry and Biobehavioural Sciences, Neuropsychiatric Institute, Brain Research Institute, David Geffen School of Medicine, University of California, Los Angeles 90095, USA
Nat Rev Neurosci 7:942-51. 2006..Here, we review the neurophysiology of the mirror neuron system and its role in social cognition and discuss the clinical implications of mirror neuron dysfunction...
Culture and neuroscience: additive or synergistic?Elizabeth A Reynolds Losin
Interdepartmental Neuroscience Program, University of California Los Angeles, Los Angeles, CA 90095, USA
Soc Cogn Affect Neurosci 5:148-58. 2010....
Altered integration of speech and gesture in children with autism spectrum disordersAmy L Hubbard
Ahmanson Lovelace Brain Mapping Center, University of California Los Angeles, California Department of Modern Languages, Carnegie Mellon University Pittsburgh, Pennsylvania Department of Computational Brain Imaging, Neural Information Analysis Laboratories Kyoto, Japan
Brain Behav 2:606-19. 2012....
Reduced functional integration and segregation of distributed neural systems underlying social and emotional information processing in autism spectrum disordersJeffrey D Rudie
Ahmanson Lovelace Brain Mapping Center, University of California, Los Angeles, 660 Charles E Young Drive South, Los Angeles, CA 90095 7085, USA
Cereb Cortex 22:1025-37. 2012..We propose that a systems-level approach-whereby the integration and segregation of large-scale brain networks in ASD is examined in relation to typical development-may provide a more detailed characterization of the neural basis of ASD...
The neural basis of speech parsing in children and adultsKristin McNealy
Ahmanson Lovelace Brain Mapping Center, Semel Institute for Neuroscience and Human Behaviour, University of California, Los Angeles, USA
Dev Sci 13:385-406. 2010..Finally, comparisons between activity observed in these children and that in previously studied adults indicate significant developmental changes in the neural substrate of speech parsing...
Reward processing in autismAshley A Scott-Van Zeeland
Center for Cognitive Neuroscience, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California, USA
Autism Res 3:53-67. 2010..Together, these data support the hypothesis that children with ASD have diminished neural responses to SR, and that this deficit relates to social learning impairments...
Behavioral profiles of affected and unaffected siblings of children with autism: contribution of measures of mother-infant interaction and nonverbal communicationAgata Rozga
Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA, USA
J Autism Dev Disord 41:287-301. 2011..However, by 12 months, infants in the ASD group exhibited lower rates of joint attention and requesting behaviors. In contrast, NoASD-sibs did not differ from comparison infants on any variables of interest at 6 and 12 months...
Giving speech a hand: gesture modulates activity in auditory cortex during speech perceptionAmy L Hubbard
Ahmanson Lovelace Brain Mapping Center, University of California, Los Angeles, California 90095 7085, USA
Hum Brain Mapp 30:1028-37. 2009..Taken together, these findings suggest a common neural substrate for processing speech and gesture, likely reflecting their joint communicative role in social interactions...
Altered functional connectivity in frontal lobe circuits is associated with variation in the autism risk gene CNTNAP2Ashley A Scott-Van Zeeland
Center for Cognitive Neuroscience, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
Sci Transl Med 2:56ra80. 2010..The convergence between genetic findings and cognitive-behavioral models of autism provides evidence that genetic variation at CNTNAP2 predisposes to diseases such as autism in part through modulation of frontal lobe connectivity...
Altered structural brain connectivity in healthy carriers of the autism risk gene, CNTNAP2Emily L Dennis
Laboratory of Neuro Imaging, Ahmanson Lovelace Brain Mapping Center, UCLA School of Medicine, Los Angeles, California 90095 7334, USA
Brain Connect 1:447-59. 2011..This is the first study that links graph theory metrics of brain structural connectivity to a common genetic variant linked with autism and will help us understand the neurobiology of the circuits implicated in the risk for autism...
Social status modulates neural activity in the mentalizing networkKeely A Muscatell
Department of Psychology, UCLA, Los Angeles, CA 90095 1563, USA
Neuroimage 60:1771-7. 2012..These studies demonstrate that social status is fundamentally and neurocognitively linked to how people process and navigate their social worlds...
Race modulates neural activity during imitationElizabeth A Reynolds Losin
Interdepartmental Neuroscience Program, University of California Los Angeles, Los Angeles, CA 90095 7085, USA
Neuroimage 59:3594-603. 2012..Our findings represent a first step in elucidating neural mechanisms involved in cultural learning, a process that influences almost every aspect of our lives but has thus far received little neuroscientific study...
"I know you are but what am I?!": neural bases of self- and social knowledge retrieval in children and adultsJennifer H Pfeifer
Department of Psychology, University of California, Los Angeles, CA 90095, USA
J Cogn Neurosci 19:1323-37. 2007..Only children activated the MPFC significantly above baseline during self-knowledge retrieval. Implications for social cognitive development and the processing functions performed by the MPFC are discussed...
Relationships between brain activation and brain structure in normally developing childrenLisa H Lu
UCLA Laboratory of Neuro Imaging, Department of Neurology, Los Angeles, CA 90095, USA
Cereb Cortex 19:2595-604. 2009..These results localized cortical regions where mature morphology corresponds to mature patterns of activation, and may suggest a role for experience in mediating brain structure-activation relationships...
Metaphorical vs. literal word meanings: fMRI evidence against a selective role of the right hemisphereSusan S Lee
Department of Psychiatry and Biobehavioral Sciences, Ahmanson-Lovelace Brain Mapping Center, UCLA, 660 Charles Young Drive South, Los Angeles, CA 90095, USA
Neuroimage 29:536-44. 2006....
Abnormal social reward processing in autism as indexed by pupillary responses to happy facesLeigh Sepeta
Department of Psychology, University of California, Los Angeles, CA, 90095, USA
J Neurodev Disord 4:17. 2012..abstract:..
Cracking the language code: neural mechanisms underlying speech parsingKristin McNealy
Ahmanson-Lovelace Brain Mapping Center, Semel Institute for Neuroscience and Human Behavior, Los Angeles, California 90095, USA
J Neurosci 26:7629-39. 2006....
Own-gender imitation activates the brain's reward circuitryElizabeth A Reynolds Losin
UCLA Interdepartmental Neuroscience Program, Ahmanson Lovelace Brain Mapping Center, Room 237, 660 Charles E Young Drive South, Los Angeles, CA 90095 7085, USA
Soc Cogn Affect Neurosci 7:804-10. 2012..Taken together, these findings reveal a neurobiological mechanism associated with the own-gender imitation bias and demonstrate a novel role of reward-processing neural structures in social behavior...
fMRI of syntactic processing in typically developing children: structural correlates in the inferior frontal gyrusS Christopher Nunez
Developmental Cognitive Neuroimaging Laboratory, Department of Neurology, University of California, Los Angeles, Los Angeles, California 90095 1769, USA
Dev Cogn Neurosci 1:313-23. 2011..Overall, our findings show relationships between structural and functional neurodevelopment that co-occur with improved syntactic processing in critical language regions of the IFG in typically developing children...
Culture in the mind's mirror: how anthropology and neuroscience can inform a model of the neural substrate for cultural imitative learningElizabeth A Reynolds Losin
Interdepartmental Neuroscience Program, University of California Los Angeles, Los Angeles, CA, USA
Prog Brain Res 178:175-90. 2009..Finally, we discuss future studies needed to test this model and fully explore and explain the neural underpinnings of cultural imitative learning...
The neural correlates of grammatical gender decisions in SpanishArturo E Hernandez
Department of Psychology, University of Houston, 126 Heyne Building, Houston, TX 77204 5022, USA
Neuroreport 15:863-6. 2004..Taken together they support the notion that gender decisions for opaque items requires deeper and more effortful processing during the retrieval of lexical and syntactic information...
Research Grants
- Neuroimaging Language in the Normally Developing BrainMirella Dapretto; Fiscal Year: 2003..abstract_text> ..
