Tobias B Dansen

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Regulation of sterol carrier protein gene expression by the forkhead transcription factor FOXO3a
    Tobias B Dansen
    Department of Biochemistry of Lipids, Institute of Biomembranes, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
    J Lipid Res 45:81-8. 2004
  2. ncbi request reprint Bid mediates apoptotic synergy between tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and DNA damage
    V Courtney Broaddus
    Lung Biology Center, San Francisco General Hospital, University of California San Francisco, San Francisco, California 94143 0854, USA
    J Biol Chem 280:12486-93. 2005
  3. ncbi request reprint The peroxisomal lumen in Saccharomyces cerevisiae is alkaline
    Carlo W T van Roermund
    Department of Clinical Chemistry, University of Amsterdam, Academic Medical Centre, PO Box 22700, 1100 DE, Amsterdam, The Netherlands
    J Cell Sci 117:4231-7. 2004
  4. ncbi request reprint Radiation-induced caspase-8 mediates p53-independent apoptosis in glioma cells
    Golnar Afshar
    Department of Radiation Oncology, University of California at San Francisco, 94143 1708, USA
    Cancer Res 66:4223-32. 2006
  5. ncbi request reprint Malignant mesothelioma cells are rapidly sensitized to TRAIL-induced apoptosis by low-dose anisomycin via Bim
    Keith S Abayasiriwardana
    Lung Biology Center, Box 0854, University of California San Francisco, San Francisco, CA 94110 0854, USA
    Mol Cancer Ther 6:2766-76. 2007
  6. ncbi request reprint Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
    Geert J P L Kops
    Department of Physiological Chemistry, University Medical Center Utrecht and Center for Biomedical Genetics, 3584 CG Utrecht, The Netherlands
    Nature 419:316-21. 2002
  7. ncbi request reprint Specific requirement for Bax, not Bak, in Myc-induced apoptosis and tumor suppression in vivo
    Tobias B Dansen
    Cancer Research Institute and Department of Cellular and Molecular Pharmacology, Comprehensive Cancer Center, University of California at San Francisco, San Francisco, California 94143 0875, USA
    J Biol Chem 281:10890-5. 2006
  8. ncbi request reprint Glucose withdrawal induces oxidative stress followed by apoptosis in glioblastoma cells but not in normal human astrocytes
    Nannette Jelluma
    Department of Radiation Oncology, University of California at San Francisco, San Francisco, California, USA
    Mol Cancer Res 4:319-30. 2006

Collaborators

  • Ronald J A Wanders
  • Johannes L Bos
  • Boudewijn M T Burgering
  • V Broaddus
  • Rene H Medema
  • Paul J Coffer
  • Nannette Jelluma
  • Keith S Abayasiriwardana
  • Gerard I Evan
  • Golnar Afshar
  • Daphne A Haas-Kogan
  • Xiaodong Yang
  • Carlo W T van Roermund
  • Geert J P L Kops
  • Ki Up Kim
  • Claire Vivo
  • Abigail E Hunt
  • Kevin K Lee
  • Dario Barbone
  • Daniel Basila
  • Erich Koller
  • Amelia Karlsson
  • David Stokoe
  • Garret L Yount
  • Nils D Arvold
  • Hans R Waterham
  • Lodewijk IJlst
  • Jan van Marle
  • Mark de Jong
  • Ingrid Saarloos
  • Karel W A Wirtz
  • Ting T Huang
  • Paulien E Polderman

Detail Information

Publications8

  1. ncbi request reprint Regulation of sterol carrier protein gene expression by the forkhead transcription factor FOXO3a
    Tobias B Dansen
    Department of Biochemistry of Lipids, Institute of Biomembranes, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
    J Lipid Res 45:81-8. 2004
    ..We propose a model for the way in which SCP2 could protect fatty acids from peroxidation...
  2. ncbi request reprint Bid mediates apoptotic synergy between tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and DNA damage
    V Courtney Broaddus
    Lung Biology Center, San Francisco General Hospital, University of California San Francisco, San Francisco, California 94143 0854, USA
    J Biol Chem 280:12486-93. 2005
    ..Such studies indicate how the adroit combination of differing proapoptotic and sublethal signals can provide an effective strategy for treating refractory tumors...
  3. ncbi request reprint The peroxisomal lumen in Saccharomyces cerevisiae is alkaline
    Carlo W T van Roermund
    Department of Clinical Chemistry, University of Amsterdam, Academic Medical Centre, PO Box 22700, 1100 DE, Amsterdam, The Netherlands
    J Cell Sci 117:4231-7. 2004
    ..1+/-0.2 in pxa2 Delta cells. Our combined results suggest that the proton gradient across the peroxisomal membrane is dependent on Ant1p activity and required for the beta-oxidation of medium chain fatty acids...
  4. ncbi request reprint Radiation-induced caspase-8 mediates p53-independent apoptosis in glioma cells
    Golnar Afshar
    Department of Radiation Oncology, University of California at San Francisco, 94143 1708, USA
    Cancer Res 66:4223-32. 2006
    ..This model may explain why p53 mutations in adult gliomas paradoxically correlate with improved survival and enhanced response to radiation...
  5. ncbi request reprint Malignant mesothelioma cells are rapidly sensitized to TRAIL-induced apoptosis by low-dose anisomycin via Bim
    Keith S Abayasiriwardana
    Lung Biology Center, Box 0854, University of California San Francisco, San Francisco, CA 94110 0854, USA
    Mol Cancer Ther 6:2766-76. 2007
    ..Such subtoxic approaches to sensitization may enhance the value of TRAIL in cancer therapy...
  6. ncbi request reprint Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
    Geert J P L Kops
    Department of Physiological Chemistry, University Medical Center Utrecht and Center for Biomedical Genetics, 3584 CG Utrecht, The Netherlands
    Nature 419:316-21. 2002
    ..The model of Forkhead involvement in regulating longevity stems from genetic analysis in Caenorhabditis elegans, and we conclude that this model also extends to mammalian systems...
  7. ncbi request reprint Specific requirement for Bax, not Bak, in Myc-induced apoptosis and tumor suppression in vivo
    Tobias B Dansen
    Cancer Research Institute and Department of Cellular and Molecular Pharmacology, Comprehensive Cancer Center, University of California at San Francisco, San Francisco, California 94143 0875, USA
    J Biol Chem 281:10890-5. 2006
    ..Furthermore, blockade of Myc-induced apoptosis by the inactivation of Bax, but not Bak, eliminates all restraints to the oncogenic potential of Myc, allowing the rapid and synchronous progression of invasive, angiogenic tumors...
  8. ncbi request reprint Glucose withdrawal induces oxidative stress followed by apoptosis in glioblastoma cells but not in normal human astrocytes
    Nannette Jelluma
    Department of Radiation Oncology, University of California at San Francisco, San Francisco, California, USA
    Mol Cancer Res 4:319-30. 2006
    ..This study implicates glycolysis as a potentially efficient and selective target for glioblastoma multiforme treatment...