Christina Tenenhaus Dann
Affiliation: University of Texas Southwestern Medical Center
- Heritable and stable gene knockdown in ratsChristina Tenenhaus Dann
The Cecil H and Ida Green Center for Reproductive Biology Sciences, Department of Pharmacology, University of Texas Southwestern Medical Center, 6001 Forest Park Road, Dallas, TX 75390 9051, USA
Proc Natl Acad Sci U S A 103:11246-51. 2006..This study demonstrates an efficient system by which directed reverse genetic analysis can now be performed in the rat...
- New technology for an old favorite: lentiviral transgenesis and RNAi in ratsChristina Tenenhaus Dann
Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9051, USA
Transgenic Res 16:571-80. 2007..Emphasis is placed on the application of in vivo RNAi, and other reverse genetic methods, for creating new genetic models in the rat...
- Production of knockdown rats by lentiviral transduction of embryos with short hairpin RNA transgenesChristina Tenenhaus Dann
Department of Pharmacology and Cecil H and Ida Green Center for Reproductive Biology Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA
Methods Mol Biol 450:193-209. 2008..This system has been used to generate a transgenic line with stable and heritable knockdown of the gene Deleted in Azoospermia-like (Dazl), resulting in male sterility and germline transmission of the transgene through females...
- Spermatogonial stem cell self-renewal requires OCT4, a factor downregulated during retinoic acid-induced differentiationChristina Tenenhaus Dann
Departments of Pediatrics, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA
Stem Cells 26:2928-37. 2008..Disclosure of potential conflicts of interest is found at the end of this article...