Research Topics
Species | Christina Tenenhaus DannSummaryAffiliation: University of Texas Southwestern Medical Center Country: USA Publications
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Detail Information
Publications
Heritable and stable gene knockdown in ratsChristina Tenenhaus Dann
The Cecil H and Ida Green Center for Reproductive Biology Sciences, Department of Pharmacology, University of Texas Southwestern Medical Center, 6001 Forest Park Road, Dallas, TX 75390 9051, USA
Proc Natl Acad Sci U S A 103:11246-51. 2006..This study demonstrates an efficient system by which directed reverse genetic analysis can now be performed in the rat...
New technology for an old favorite: lentiviral transgenesis and RNAi in ratsChristina Tenenhaus Dann
Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9051, USA
Transgenic Res 16:571-80. 2007..Emphasis is placed on the application of in vivo RNAi, and other reverse genetic methods, for creating new genetic models in the rat...
Production of knockdown rats by lentiviral transduction of embryos with short hairpin RNA transgenesChristina Tenenhaus Dann
Department of Pharmacology and Cecil H and Ida Green Center for Reproductive Biology Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA
Methods Mol Biol 450:193-209. 2008..This system has been used to generate a transgenic line with stable and heritable knockdown of the gene Deleted in Azoospermia-like (Dazl), resulting in male sterility and germline transmission of the transgene through females...
Spermatogonial stem cell self-renewal requires OCT4, a factor downregulated during retinoic acid-induced differentiationChristina Tenenhaus Dann
Departments of Pediatrics, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA
Stem Cells 26:2928-37. 2008..Disclosure of potential conflicts of interest is found at the end of this article...
