Genomes and Genes
Affiliation: University of California
- Genetic mouse models to study blood-brain barrier development and functionFabien Sohet
UCSF Department of Anatomy, 513 Parnassus Ave HSW1301, San Francisco, 94117, California, USA
Fluids Barriers CNS 10:3. 2013....
- The blood-brain barrier in health and diseaseRichard Daneman
Department of Anatomy, University of California San Francisco, CA, USA
Ann Neurol 72:648-72. 2012..I further discuss what is known about BBB dysfunction during CNS injury and disease, as well as methodology used to deliver drugs across the BBB to the CNS...
- The gut immune barrier and the blood-brain barrier: are they so different?Richard Daneman
University of California, San Francisco, Department of Anatomy, San Francisco, CA 94143 0452, USA
Immunity 31:722-35. 2009..These barrier cells interact with different cell types, which dynamically regulate their function, and with a different array of immune cells that survey the physical barrier and provide innate and adaptive immunity...
- Pericytes are required for blood-brain barrier integrity during embryogenesisRichard Daneman
UCSF Department of Anatomy, 513 Parnassus Avenue, HSW1301, San Francisco, California 94143 0452, USA
Nature 468:562-6. 2010..These data indicate that pericyte-endothelial cell interactions are critical to regulate the BBB during development, and disruption of these interactions may lead to BBB dysfunction and neuroinflammation during CNS injury and disease...
- The mouse blood-brain barrier transcriptome: a new resource for understanding the development and function of brain endothelial cellsRichard Daneman
Department of Anatomy, University of California San Francisco, San Francisco, California, United States of America
PLoS ONE 5:e13741. 2010..This dataset provides a resource for understanding CNS endothelial cells and their interaction with neural and hematogenous cells...
- Blood-brain barrier permeability is increased after acute adult stroke but not neonatal stroke in the ratDavid Fernández-López
Department of Neurology, University of California San Francisco, San Francisco, California 94143 0633, USA
J Neurosci 32:9588-600. 2012..The markedly more integrant BBB in neonatal brain than in adult brain after acute stroke may have major implications for the treatment of neonatal stroke...