RAIMONDO D'AMBROSIO

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. pmc Mild passive focal cooling prevents epileptic seizures after head injury in rats
    RAIMONDO D'AMBROSIO
    Department of Neurological Surgery, University of Washington, Seattle, WA, USA
    Ann Neurol 73:199-209. 2013
  2. ncbi request reprint Differential role of KIR channel and Na(+)/K(+)-pump in the regulation of extracellular K(+) in rat hippocampus
    RAIMONDO D'AMBROSIO
    Department of Neurological Surgery, University of Washington, School of Medicine, Harborview Medical Center, Seattle, Washington 98104, USA
    J Neurophysiol 87:87-102. 2002
  3. pmc Functional definition of seizure provides new insight into post-traumatic epileptogenesis
    RAIMONDO D'AMBROSIO
    Department of Neurological Surgery, School of Medicine, University of Washington Harborview Medical Center, 325 Ninth Avenue, Seattle, WA 98104, USA
    Brain 132:2805-21. 2009
  4. pmc Antiepileptic and antiepileptogenic performance of carisbamate after head injury in the rat: blind and randomized studies
    Clifford L Eastman
    Department of Neurosurgery, University of Washington, Seattle, WA, USA
    J Pharmacol Exp Ther 336:779-90. 2011
  5. pmc Progression from frontal-parietal to mesial-temporal epilepsy after fluid percussion injury in the rat
    RAIMONDO D'AMBROSIO
    Department of Neurological Surgery, Center on Human Development and Disability, University of Washington, School of Medicine, Harborview Medical Center, Box 359915, 325 Ninth Avenue, Seattle, WA 98104, USA
    Brain 128:174-88. 2005
  6. pmc Epilepsy after head injury
    RAIMONDO D'AMBROSIO
    Department of Neurological Surgery and Regional Epilepsy Center, University of Washington, Seattle, Washington, USA
    Curr Opin Neurol 17:731-5. 2004
  7. ncbi request reprint The role of glial membrane ion channels in seizures and epileptogenesis
    RAIMONDO D'AMBROSIO
    Department of Neurological Surgery and Regional Epilepsy Center, University of Washington, Box 359914, 325 Ninth Avenue, Seattle, WA 98104, USA
    Pharmacol Ther 103:95-108. 2004
  8. pmc Post-traumatic epilepsy following fluid percussion injury in the rat
    RAIMONDO D'AMBROSIO
    Department of Neurological Surgery, Center on Human Development and Disability, University of Washington, School of Merdicine, Harborview Medical Center, Box 359914, 325 Ninth Ave, Seattle, WA 98104, USA
    Brain 127:304-14. 2004
  9. pmc ECoG studies of valproate, carbamazepine and halothane in frontal-lobe epilepsy induced by head injury in the rat
    Clifford L Eastman
    Department of Neurological Surgery, University of Washington, School of Medicine, Seattle, WA 98104, USA
    Exp Neurol 224:369-88. 2010
  10. pmc Chronic dysfunction of astrocytic inwardly rectifying K+ channels specific to the neocortical epileptic focus after fluid percussion injury in the rat
    Tessandra H Stewart
    Department of Neurological Surgery, University of Washington, School of Medicine, Seattle, USA
    J Neurophysiol 104:3345-60. 2010

Collaborators

Detail Information

Publications18

  1. pmc Mild passive focal cooling prevents epileptic seizures after head injury in rats
    RAIMONDO D'AMBROSIO
    Department of Neurological Surgery, University of Washington, Seattle, WA, USA
    Ann Neurol 73:199-209. 2013
    ..We examined the effect of mild passive focal cooling of the perilesional neocortex on the development of neocortical epileptic seizures after head injury in the rat...
  2. ncbi request reprint Differential role of KIR channel and Na(+)/K(+)-pump in the regulation of extracellular K(+) in rat hippocampus
    RAIMONDO D'AMBROSIO
    Department of Neurological Surgery, University of Washington, School of Medicine, Harborview Medical Center, Seattle, Washington 98104, USA
    J Neurophysiol 87:87-102. 2002
    ..The results presented provide new insights into the specific physiological role of glial KIR channels in extracellular K(+) homeostasis...
  3. pmc Functional definition of seizure provides new insight into post-traumatic epileptogenesis
    RAIMONDO D'AMBROSIO
    Department of Neurological Surgery, School of Medicine, University of Washington Harborview Medical Center, 325 Ninth Avenue, Seattle, WA 98104, USA
    Brain 132:2805-21. 2009
    ....
  4. pmc Antiepileptic and antiepileptogenic performance of carisbamate after head injury in the rat: blind and randomized studies
    Clifford L Eastman
    Department of Neurosurgery, University of Washington, Seattle, WA, USA
    J Pharmacol Exp Ther 336:779-90. 2011
    ..The data support the use of rpFPI-induced PTE in the adolescent rat as a model of pharmacoresistant epilepsy for preclinical development...
  5. pmc Progression from frontal-parietal to mesial-temporal epilepsy after fluid percussion injury in the rat
    RAIMONDO D'AMBROSIO
    Department of Neurological Surgery, Center on Human Development and Disability, University of Washington, School of Medicine, Harborview Medical Center, Box 359915, 325 Ninth Avenue, Seattle, WA 98104, USA
    Brain 128:174-88. 2005
    ..These observations establish numerous similarities between FPI-induced and human PTE and further validate it as a clinically relevant model of PTE...
  6. pmc Epilepsy after head injury
    RAIMONDO D'AMBROSIO
    Department of Neurological Surgery and Regional Epilepsy Center, University of Washington, Seattle, Washington, USA
    Curr Opin Neurol 17:731-5. 2004
    ..The purpose of this short review is to provide an update on the epidemiology of posttraumatic epilepsy, associated risk factors, data from prevention studies, and recent breakthroughs in experimental research...
  7. ncbi request reprint The role of glial membrane ion channels in seizures and epileptogenesis
    RAIMONDO D'AMBROSIO
    Department of Neurological Surgery and Regional Epilepsy Center, University of Washington, Box 359914, 325 Ninth Avenue, Seattle, WA 98104, USA
    Pharmacol Ther 103:95-108. 2004
    ....
  8. pmc Post-traumatic epilepsy following fluid percussion injury in the rat
    RAIMONDO D'AMBROSIO
    Department of Neurological Surgery, Center on Human Development and Disability, University of Washington, School of Merdicine, Harborview Medical Center, Box 359914, 325 Ninth Ave, Seattle, WA 98104, USA
    Brain 127:304-14. 2004
    ....
  9. pmc ECoG studies of valproate, carbamazepine and halothane in frontal-lobe epilepsy induced by head injury in the rat
    Clifford L Eastman
    Department of Neurological Surgery, University of Washington, School of Medicine, Seattle, WA 98104, USA
    Exp Neurol 224:369-88. 2010
    ..The data also demonstrate the utility of chronic exposures to experimental drugs in preclinical studies and highlight the need for greater attention to etiology in clinical studies of AEDs...
  10. pmc Chronic dysfunction of astrocytic inwardly rectifying K+ channels specific to the neocortical epileptic focus after fluid percussion injury in the rat
    Tessandra H Stewart
    Department of Neurological Surgery, University of Washington, School of Medicine, Seattle, USA
    J Neurophysiol 104:3345-60. 2010
    ....
  11. pmc Progressive dendritic HCN channelopathy during epileptogenesis in the rat pilocarpine model of epilepsy
    Sangwook Jung
    Department of Neurology, University of Washington, Seattle, Washington 98104, USA
    J Neurosci 27:13012-21. 2007
    ..This early and progressive downregulation of dendritic HCN channel function increases neuronal excitability and may be associated with both the process of epileptogenesis and maintenance of the epileptic state...
  12. doi request reprint Long-term outcome of extratemporal resection in posttraumatic epilepsy
    Shahin Hakimian
    Department of Neurology, University of Washington, USA
    Neurosurg Focus 32:E10. 2012
    ..The authors investigated and characterized the long-term outcome and patient factors associated with outcome in this population...
  13. doi request reprint Novel frontiers in epilepsy treatments: preventing epileptogenesis by targeting inflammation
    RAIMONDO D'AMBROSIO
    Department of Neurological Surgery, University of Washington, Seattle, WA, USA
    Expert Rev Neurother 13:615-25. 2013
    ..If results of such studies are positive, these compounds could rapidly enter Phase III trials in patients at high risk of developing epilepsy...
  14. doi request reprint Comparing noninvasive dense array and intracranial electroencephalography for localization of seizures
    Mark D Holmes
    Regional Epilepsy Center, Department of Neurology, University of Washington, Seattle, Washington 98104, USA
    Neurosurgery 66:354-62. 2010
    ....
  15. ncbi request reprint New insights into neuromodulatory approaches for the treatment of pain
    Mark P Jensen
    Department of Rehabilitation Medicine, University of Washington School of Medicine, Seattle, Washington 98195 6490, USA
    J Pain 9:193-9. 2008
    ....
  16. ncbi request reprint Adenosine receptors mediate glutamate-evoked arteriolar dilation in the rat cerebral cortex
    Jeffrey J Iliff
    Department of Neurological Surgery, University of Washington School of Medicine, Harborview Medical Center, 325 Ninth Avenue, Seattle, WA 98104, USA
    Am J Physiol Heart Circ Physiol 284:H1631-7. 2003
    ..These results suggest that Ado contributes to the dilation of rat cerebral arterioles induced by exogenous glutamate, and that the Ado A(2A) receptor subtype may be involved in this dilation response...
  17. ncbi request reprint Hippocampal injury and neurobehavioral deficits are improved by PD 81,723 following hyperglycemic cerebral ischemia
    Joseph R Meno
    Department of Neurological Surgery, University of Washington, Seattle, WA 98104, USA
    Exp Neurol 183:188-96. 2003
    ..Moreover, the present study provides further evidence for a neuromodulatory role of adenosine during hyperglycemic ischemia...
  18. ncbi request reprint Rufinamide: a new anti-epileptic medication
    Shahin Hakimian
    University of Washington, Regional Epilepsy Center, Harborview Medical Center, Seattle, WA 98104, USA
    Expert Opin Pharmacother 8:1931-40. 2007
    ..Rufinamide has shown promise as adjunctive treatment for Lennox-Gastaut syndrome and may have some role in localization related epilepsies as well...

Research Grants9

  1. Pathophysiology of glia following traumatic brain injury
    RAIMONDO D AMBROSIO; Fiscal Year: 2002
    ..Investigations on these post-traumatic changes will allow a more rational treatment to TBI. ..
  2. Pathophysiology of glia following traumatic brain injury
    RAIMONDO D AMBROSIO; Fiscal Year: 2003
    ..Investigations on these post-traumatic changes will allow a more rational treatment to TBI. ..
  3. Pathophysiology of glia following traumatic brain injury
    RAIMONDO D AMBROSIO; Fiscal Year: 2004
    ..Investigations on these post-traumatic changes will allow a more rational treatment to TBI. ..
  4. Pathophysiology of glia following traumatic brain injury
    RAIMONDO D AMBROSIO; Fiscal Year: 2005
    ..Investigations on these post-traumatic changes will allow a more rational treatment to TBI. ..
  5. Posttraumatic epilepsy induced by fluid percussion injury in the rat
    RAIMONDO D AMBROSIO; Fiscal Year: 2006
    ....
  6. Posttraumatic epilepsy induced by fluid percussion injury in the rat
    RAIMONDO D AMBROSIO; Fiscal Year: 2007
    ....
  7. Posttraumatic epilepsy induced by fluid percussion injury in the rat
    RAIMONDO D AMBROSIO; Fiscal Year: 2009
    ..abstract_text> ..
  8. Posttraumatic epilepsy induced by fluid percussion injury in the rat
    RAIMONDO D apos AMBROSIO; Fiscal Year: 2010
    ..abstract_text> ..