Research Topics
Species | Josep DalmauSummaryAffiliation: University of Pennsylvania Country: USA Publications
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Detail Information
Publications
Paraneoplastic encephalitis, psychiatric symptoms, and hypoventilation in ovarian teratomaRoberta Vitaliani
Division of Neuro Oncology, Department of Neurology, University of Pennsylvania, Philadelphia, PA 19104, USA
Ann Neurol 58:594-604. 2005..Recognition of this disorder is important because despite the severity of the symptoms, patients usually recover. The location and function of the isolated antigen suggest that the disorder is directly mediated by antibodies...- Antibodies to the GABA(B) receptor in limbic encephalitis with seizures: case series and characterisation of the antigenEric Lancaster
Department of Neurology, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104, USA
Lancet Neurol 9:67-76. 2010..Some encephalitides or seizure disorders once thought idiopathic now seem to be immune mediated. We aimed to describe the clinical features of one such disorder and to identify the autoantigen involved... - Investigation of LGI1 as the antigen in limbic encephalitis previously attributed to potassium channels: a case seriesMeizan Lai
Department of Neurology, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104, USA
Lancet Neurol 9:776-85. 2010..However, antibody testing using cells expressing voltage-gated potassium channels is negative; hence, we aimed to identify the real autoantigen associated with limbic encephalitis... - In vivo effects of antibodies from patients with anti-NMDA receptor encephalitis: further evidence of synaptic glutamatergic dysfunctionMario Manto
FNRS Laboratoire de Neurologie Expérimentale, ULB, Belgium
Orphanet J Rare Dis 5:31. 2010..Patients' antibodies cause a decrease of the density of NMDA-R and synaptic mediated currents, but the in vivo effects on the extracellular glutamate and glutamatergic transmission are unknown... - Clinical and immunological diversity of limbic encephalitis: a model for paraneoplastic neurologic disordersJosep Dalmau
Department of Neurology, Section of Neuro Oncology, University of Pennsylvania, 3 Gates Building, 3400 Spruce Street, Philadelphia, PA 19104, USA
Hematol Oncol Clin North Am 20:1319-35. 2006..This article summarizes the authors' findings of limbic encephalitis and postulates that a similar approach can be used for syndromes involving other areas of the nervous system... - Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodiesJosep Dalmau
Department of Neurology, University of Pennsylvania, Philadelphia, PA 19104, USA
Lancet Neurol 7:1091-8. 2008..We aimed to analyse the clinical and immunological features of patients with the disorder and examine the effects of antibodies against NMDA receptors in neuronal cultures... - Paraneoplastic syndromes of the CNSJosep Dalmau
Division of Neuro Oncology, Department of Neurology, University of Pennsylvania, Philadelphia 19104, USA
Lancet Neurol 7:327-40. 2008..In this article, we review some classic concepts about PND and recent clinical and immunological developments, focusing on paraneoplastic cerebellar degeneration, opsoclonus-myoclonus, and encephalitides affecting the limbic system... - Paraneoplastic anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratomaJosep Dalmau
Department of Neurology, Division of Neuro Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA
Ann Neurol 61:25-36. 2007..To report the autoantigens of a new category of treatment-responsive paraneoplastic encephalitis... - Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitisJosep Dalmau
Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Lancet Neurol 10:63-74. 2011..On the basis of models of pharmacological or genetic disruption of NMDAR, these antibody effects reveal a probable pathogenic relation between the depletion of receptors and the clinical features of anti-NMDAR encephalitis... - AMPA receptor antibodies in limbic encephalitis alter synaptic receptor locationMeizan Lai
Department of Neurology, University of Pennsylvania, Philadelphia, PA 19104, USA
Ann Neurol 65:424-34. 2009..To report the clinical and immunological features of a novel autoantigen related to limbic encephalitis (LE) and the effect of patients' antibodies on neuronal cultures... - Cellular and synaptic mechanisms of anti-NMDA receptor encephalitisEthan G Hughes
Department of Neuroscience, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
J Neurosci 30:5866-75. 2010..The loss of this subtype of glutamate receptors eliminates NMDAR-mediated synaptic function, resulting in the learning, memory, and other behavioral deficits observed in patients with anti-NMDAR encephalitis... - Evidence for antibody-mediated pathogenesis in anti-NMDAR encephalitis associated with ovarian teratomaErdem Tuzun
Division of Neuro Oncology, Department of Neurology, Hospital of the University of Pennsylvania, University of Pennsylvania, 3 W Gates, 3400 Spruce Street, Philadelphia, PA 19104, USA
Acta Neuropathol 118:737-43. 2009.... 
Limbic encephalitis and variants related to neuronal cell membrane autoantigensJosep Dalmau
Division of Neuro Oncology, Department of Neurology, Hospital of the University of Pennsylvania, 3400 Spruce Street Philadelphia, PA 19104, USA
Rinsho Shinkeigaku 48:871-4. 2008..In all, the study of these disorders provides a link between immunologic processes and neuronal events involved in memory, cognition, seizures, and neuronal degeneration...- Mechanisms underlying autoimmune synaptic encephalitis leading to disorders of memory, behavior and cognition: insights from molecular, cellular and synaptic studiesEmilia H Moscato
Department of Neuroscience, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6074, USA
Eur J Neurosci 32:298-309. 2010.... - Investigations of caspr2, an autoantigen of encephalitis and neuromyotoniaEric Lancaster
Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, 19104, USA
Ann Neurol 69:303-11. 2011.... 
Neuronal autoantigens--pathogenesis, associated disorders and antibody testingEric Lancaster
Department of Neurology, 3 W Gates, 3400 Spruce Street, University of Pennsylvania, Philadelphia, PA 19104, USA
Nat Rev Neurol 8:380-90. 2012..We also provide an algorithm to identify and assess antibodies that bind to cell-surface and synaptic antigens...- Case records of the Massachusetts General Hospital. Case 4-2007. A 56-year-old woman with rapidly progressive vertigo and ataxiaJosep Dalmau
Division of Neuro-Oncology, Department of Neurology, Hospital of the University of Pennsylvania, University of Pennsylvania, Philadelphia, USA
N Engl J Med 356:612-20. 2007 - Paraneoplastic cerebellar degeneration: Yo-expressing tumor revealed after a 5-year follow-up with FDG-PETRose Marie Mathew
Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA, United States
J Neurol Sci 250:153-5. 2006..An overwhelming majority of anti-Yo positive patients eventually develop a detectable malignancy, which argues in favor of a poorly effective or non-sustained anti-tumor immune response... - Treatment-responsive limbic encephalitis identified by neuropil antibodies: MRI and PET correlatesBeau M Ances
Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
Brain 128:1764-77. 2005.... - Encephalitis and antibodies to synaptic and neuronal cell surface proteinsEric Lancaster
Department of Neurology, University of Pennsylvania, Philadelphia, PA 19104, USA
Neurology 77:179-89. 2011..This review provides an update on these syndromes and autoantigens with special emphasis on clinical diagnosis and treatment... - Psychiatric manifestations of paraneoplastic disordersMatthew S Kayser
Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
Am J Psychiatry 167:1039-50. 2010..They also discuss the broad behavioral findings that highlight the need for psychiatrists to be aware of initial presentations of paraneoplastic disorders... - Adenylate kinase 5 autoimmunity in treatment refractory limbic encephalitisErdem Tuzun
Division of Neuro Oncology, Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
J Neuroimmunol 186:177-80. 2007..Detection of antibodies to AK5 in LE patients carries a poor prognosis, and suggests the prompt use of aggressive immunosuppression... - Clinical analysis of anti-Ma2-associated encephalitisJosep Dalmau
Department of Neurology, 3 W Gates, Division of Neuro Oncology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
Brain 127:1831-44. 2004..In young male patients, the primary tumour is usually in the testis, in other patients the leading neoplasm is lung cancer... - A patient with encephalitis associated with NMDA receptor antibodiesLauren H Sansing
Hospital of the University of Pennsylvania, Philadelphia, PA, USA
Nat Clin Pract Neurol 3:291-6. 2007..There was muscle rigidity, frequent facial grimacing, rhythmic abdominal contractions, kicking motions of the legs, and intermittent dystonic postures of the right arm... - Glycine receptor autoimmune spectrum with stiff-man syndrome phenotypeAndrew McKeon
Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA
JAMA Neurol 70:44-50. 2013.... - Anti-NMDA receptor encephalitis antibody binding is dependent on amino acid identity of a small region within the GluN1 amino terminal domainAmy J Gleichman
Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
J Neurosci 32:11082-94. 2012..These findings provide tools for detailed comparison of antibodies across patients and suggest an interaction between antibody binding and channel function... - Neuro-ophthalmologic manifestations of paraneoplastic syndromesMelissa W Ko
Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
J Neuroophthalmol 28:58-68. 2008..Most of these disorders are related to immunologic mechanisms presumably triggered by the neoplastic expression of neuronal proteins. Accurate recognition is essential to appropriate management... - Autoantigen diversity in the opsoclonus-myoclonus syndromeLuis Bataller
Department of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR, USA
Ann Neurol 53:347-53. 2003.... - Glazed (vision) and confusedHeather E Moss
Division of Neuro ophthalmology, Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Surv Ophthalmol 55:169-73. 2010..The clinical presentation, pathophysiology, and therapy of CRMP5 associated paraneoplastic syndromes are discussed... - Thymoma, myasthenia gravis, encephalitis, and a novel anticytoplasmic neuronal antibodySami L Khella
Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Neurology 69:1302-3. 2007 - Current therapies for neuromuscular manifestations of paraneoplastic syndromesMyrna R Rosenfeld
Department of Neurology, Section of Neuro-Oncology, 3 West Gates, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
Curr Neurol Neurosci Rep 6:77-84. 2006..For the other disorders, adjuvant therapies are for the most part empiric and include a variety of immunosuppressant and immunomodulatory agents... - Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis in children and adolescentsNicole R Florance
Division of Neurology, Department of Pediatrics, Children s Hospital of Philadelphia, Philadelphia, PA, USA
Ann Neurol 66:11-8. 2009..To report the clinical features of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis in patients < or = 18 years old... - Extreme delta brush: a unique EEG pattern in adults with anti-NMDA receptor encephalitisSarah E Schmitt
PENN Epilepsy Center, Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia, USA
Neurology 79:1094-100. 2012..To determine continuous EEG (cEEG) patterns that may be unique to anti-NMDA receptor (NMDAR) encephalitis in a series of adult patients with this disorder... - Reversible paraneoplastic encephalitis in three patients with ovarian neoplasmsJanos L Tanyi
Division of Gynecologic Oncology, University of Pennsylvania Health System, Philadelphia, PA, USA
Acta Obstet Gynecol Scand 91:630-4. 2012..Our experience suggests that prompt syndrome recognition followed by tumor removal and immunotherapy usually results in neurological recovery... - Paraneoplastic disorders of eye movementsShirley H Wray
Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
Ann N Y Acad Sci 1233:279-84. 2011..Abnormal eye movements in paraneoplastic syndromes offer insights into the pathogenesis of these disorders and the opportunity to test potential therapies, such as new drugs with effects on neuronal channels... - Movement disorders in paraneoplastic and autoimmune diseaseJessica Panzer
Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Curr Opin Neurol 24:346-53. 2011..The most relevant advances in immune-mediated movement disorders are described, with emphasis on the clinical--immunological associations, novel antigens, and treatment... - The emerging link between autoimmune disorders and neuropsychiatric diseaseMatthew S Kayser
Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
J Neuropsychiatry Clin Neurosci 23:90-7. 2011..In this review, the authors discuss a newly recognized class of synaptic autoimmune encephalitides as well as behavioral and cognitive manifestations of systemic autoimmune diseases... - The MAZ protein is an autoantigen of Hodgkin's disease and paraneoplastic cerebellar dysfunctionLuis Bataller
Department of Neurology, University of Arkansas for Medical Sciences, Little Rock, USA
Ann Neurol 53:123-7. 2003..These findings suggest epitope spreading between the Tr antigen and the MAZ-DCC complex and offer a possible model of immune-mediated cerebellar disease... - Limbic encephalitis and variants: classification, diagnosis and treatmentErdem Tuzun
Division of Neuro Oncology, Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
Neurologist 13:261-71. 2007..This review focuses in these disorders, framed in a clinically useful immunologic classification of limbic encephalitis... - Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: an observational cohort studyMaarten J Titulaer
Department of Neurology and Neurosciences, Hospital of the University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA Department of Neurology, Hospital Clinic, The University of Barcelona d Investigacions Biomèdiques August Pi i Sunyer IDIBAPS, Spain
Lancet Neurol 12:157-65. 2013..We aimed to assess the presentation of the disease, the spectrum of symptoms, immunotherapies used, timing of improvement, and long-term outcome... - Rituximab as potential therapy for paraneoplastic cerebellar degeneration in pediatric Hodgkin diseaseKee Kiat Yeo
Thomas Jefferson University, Philadelphia, PA, USA
Pediatr Blood Cancer 58:986-7. 2012..Based on promising data in adults on the efficacy of rituximab over other immuno suppressive agents in paraneoplastic disorders, he was treated with rituximab with marked improvement of the cerebellar syndrome... - Functional analysis of CD8+ T cell responses to the onconeural self protein cdr2 in patients with paraneoplastic cerebellar degenerationErica L Carpenter
Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, United States
J Neuroimmunol 193:173-82. 2008..In contrast, viral-specific CD8(+) T cells from healthy volunteers and PCD patients were measurable. These findings are inconsistent with an obligate role for cdr2-1- or cdr2-2-specific CD8(+) T cells in the pathogenesis of PCD... - Update on paraneoplastic and autoimmune disorders of the central nervous systemMyrna R Rosenfeld
Department of Neurology, Division of Neuro Oncology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Semin Neurol 30:320-31. 2010..This review analyzes the immune responses associated with paraneoplastic and nonparaneoplastic disorders of the central nervous system, and the main clinical features and response to treatment... - Anti-N-methyl-D-aspartate receptor encephalitis during pregnancyMonisha A Kumar
Department of Neurology, University of Pennsylvania, Philadelphia, 19104, USA
Arch Neurol 67:884-7. 2010..To report 3 patients who developed anti-N-methyl-d-aspartate receptor encephalitis during pregnancy... - Paraneoplastic syndromes causing movement disordersJosep Dalmau
Division of Neuro Oncology, Department of Neurology, University of Pennsylvania, Philadelphia 19104, USA
Handb Clin Neurol 100:315-21. 2011..Understanding the natural course of each immune-mediated paraneoplastic movement disorder minimizes unnecessary testing and the use of potentially toxic therapies... - Paraneoplastic syndromes of the peripheral nervesStacy A Rudnicki
Department of Neurology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
Curr Opin Neurol 18:598-603. 2005..In many instances, prompt treatment of the tumor and immunotherapy result in symptom stabilization or neurologic improvement... - Update on anti-N-methyl-D-aspartate receptor encephalitis in children and adolescentsNicole Florance-Ryan
Division of Neurology, Department of Pediatrics, Children s Hospital of Philadelphia, and Division of Neuro Oncology, Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Curr Opin Pediatr 22:739-44. 2010..We review here the main clinical features and differential diagnosis and provide algorithms of the clinical correlates of antibody-mediated decrease of NMDAR and a suggested treatment approach... - Paraneoplastic neurologic syndromesLuis Bataller
Department of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR, USA
Neurol Clin 21:221-47, ix. 2003..PND often develop before the presence of a cancer is known and their recognition may lead to the tumor diagnosis... - Unusual neuro-ophthalmologic findings in a patient with anti-Yo-associated cerebellar degenerationAdam B Cohen
Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
J Neurol Sci 225:153-5. 2004..The prominent neuro-ophthalmologic findings suggest brainstem involvement, which may be a novel manifestation of anti-Yo associated paraneoplastic syndrome... - Update on paraneoplastic neurologic disordersMyrna R Rosenfeld
Division of Neuro Oncology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, Pennsylvania 19104, USA
Oncologist 15:603-17. 2010.... - Paraneoplastic neurological syndromesFrancesc Graus
Service of Neurology, Hospital Clinic, Universitat de Barcelona and Institut d Investigació Biomèdica August Pi i Sunyer, Barcelona, Spain
Curr Opin Neurol 25:795-801. 2012..This review describes relevant advances in paraneoplastic neurological syndromes (PNS) with emphasis on particular syndromes and the impact of antibodies against surface antigens in their management... - Clinical neuropathology practice guide 5-2012: updated guideline for the diagnosis of antineuronal antibodiesRomana Hoftberger
Institute of Neurology, Medical University of Vienna, Austria
Clin Neuropathol 31:337-41. 2012..Selection and proper combination of test systems and appropriate knowledge of the clinical information will provide a maximum of sensitivity and specificity in identifying the associated antibody... - Anti-NMDA-Receptor Encephalitis and Other Synaptic Autoimmune DisordersMyrna R Rosenfeld
Department of Neurology, University of Pennsylvania, 3 W Gates 3400 Spruce St, Philadelphia, PA, 19104, USA
Curr Treat Options Neurol 13:324-32. 2011..For example, patients with anti-NMDA-receptor encephalitis who had been in a coma or ventilated for 6-10 months have had full recovery after appropriate treatment... - Paraneoplastic neurologic disorders in childrenElizabeth M Wells
Department of Neurology, Children s National Medical Center, 111 Michigan Avenue, NW, Washington, DC, 20010, USA
Curr Neurol Neurosci Rep 11:187-94. 2011..Given the rarity of these conditions, multisite collaborative efforts are needed to develop standardized approaches to characterization and treatment... - Antibodies to metabotropic glutamate receptor 5 in the Ophelia syndromeE Lancaster
Department of Neurology, University of Pennsylvania, Philadelphia, PA 19104, USA
Neurology 77:1698-701. 2011..To report the metabotropic glutamate receptor 5 (mGluR5) as the autoantigen of antibodies from 2 patients with Hodgkin lymphoma (HL) and limbic encephalopathy (Ophelia syndrome)... - Analysis of complement and plasma cells in the brain of patients with anti-NMDAR encephalitisE Martinez-Hernandez
Department of Neurology, University of Pennsylvania, Philadelphia 19104, USA
Neurology 77:589-93. 2011..We examined whether complement immunoreactivity and antibody-secreting cells (plasma cells/plasmablasts) are present in the brain of these patients... - Inverse ocular bobbing in a patient with encephalitis associated with antibodies to the N-methyl-D-aspartate receptorHaruo Shimazaki
Division of Neurology, Department of Internal Medicine, Jichi Medical University, Yakushiji 3311-1, Shimotsuke, Tochigi 329-0498, Japan
Arch Neurol 65:1251. 2008 - Paraneoplastic neurologic syndromes: approaches to diagnosis and treatmentLuis Bataller
Department of Neurology, Hospital La Fe, Valencia, Spain
Semin Neurol 23:215-24. 2003.... - Anti-Ma2-associated encephalitis with normal FDG-PET: a case of pseudo-Whipple's diseaseJames Castle
Stanford University, CA, USA
Nat Clin Pract Neurol 2:566-72; quiz 573. 2006..MANAGEMENT: Corticosteroids, intravenous immunoglobulins, orchiectomy, muscle relaxants, mycophenolate mofetil, plasmapheresis, and bleomycin, etoposide and platinum chemotherapy... - Paraneoplastic sensory neuronopathy and spontaneous regression of small cell lung cancerSharlene Gill
Division of Medical Oncology, British Columbia Cancer Agency, Vancouver, BC, Canada
Can J Neurol Sci 30:269-71. 2003..CONCLUSIONS: This case supports the hypothesis that anti-Hu neurologic syndromes are the consequence of a misdirected immune response to small cell tumours... - Antibodies to AChR, MuSK and VGKC in a patient with myasthenia gravis and Morvan's syndromeJordi Diaz-Manera
Neuromuscular Diseases Section, Department of Neurology, at Hospital de la Santa Creu i Sant Pau in Barcelona, Spain
Nat Clin Pract Neurol 3:405-10. 2007..Mild limb weakness with severe muscle atrophy and diffuse muscle twitches were observed. The patient had also developed visual hallucinations and persecutory delusions. Her personal and family medical histories were unremarkable... - Severe hypokinesis caused by paraneoplastic anti-Ma2 encephalitis associated with bilateral intratubular germ-cell neoplasm of the testesLumine Matsumoto
Department of Neurology, The University of Tokyo, Tokyo, Japan
Mov Disord 22:728-31. 2007..Anti-Ma2 paraneoplastic encephalitis should be considered in patients with severe hypokinesis, and intensive investigation and aggressive approach to treatment is encouraged to prevent progression of the neurological deficits... - EFA6A-like antibodies in paraneoplastic encephalitis associated with immature ovarian teratoma: a case reportReiji Koide
Department of Neurology, Tokyo Metropolitan Neurological Hospital, 2 6 1 Musashidai, Fuchu, Tokyo 183 0042, Japan
J Neurooncol 81:71-4. 2007..Antibodies that colocalize with EFA6A are a valuable marker for early diagnosis of a potentially reversible paraneoplastic encephalitis associated with OT... - Treatment-responsive subacute limbic encephalitis and NMDA receptor antibodies in a manMaria Elena Novillo-López
Department of Neurology, Hospital Ramon y Cajal, Madrid, Spain
Neurology 70:728-9. 2008 - Paraneoplastic neurological syndromes: diagnosis and treatmentFrancesc Graus
aService of Neurology, Hospital Clinic, Universitat de Barcelona and Institut d Investigació Biomèdica August Pi i Sunyer IDIBAPS, Barcelona, Spain
Curr Opin Neurol 20:732-7. 2007..The most relevant advances in the field of paraneoplastic neurological syndromes are described, with special emphasis on particular clinical-immunological associations and practical issues for the diagnosis and treatment of these disorders... - Paraneoplastic recurrent multifocal encephalitis presenting with epilepsia partialis continuaMelike Mut
Department of Neurosurgery, University of Virginia, CDW Hospital Drive, P.O. Box 800212, Charlottesville, VA 22903, USA
J Neurooncol 72:63-6. 2005..The diagnostic challenges of the highly variable clinical presentations and therapeutic approaches to paraneoplastic multifocal encephalitis are discussed with relevant literature review... - Neuro-ophthalmology and paraneoplastic syndromesLuis Bataller
Department of Neurology, Hospital Universitario La Fe, Valencia, Spain
Curr Opin Neurol 17:3-8. 2004..Basic immunological studies support the pathogenic role of some of these antibodies, and are elucidating the pathogenic mechanisms that underlie these and other antibody-associated paraneoplastic syndromes... - Herpes simplex encephalitis in a patient with cancerLuis Bataller
J Neurooncol 78:211. 2006 - Anti-Hu antibodies in Merkel cell carcinomaJohn E Greenlee
Neurology Service, Veterans Affairs Medical Center and Department of Neurology, University of Utah School of Medicine, Salt Lake City, UT 84148, USA
Ann Neurol 52:111-5. 2002..The patient's serum contained antibodies against the Hu antigen, and the expression of the Hu antigen was demonstrated in the patient's tumor...