Deniz Dalkara

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Inner limiting membrane barriers to AAV-mediated retinal transduction from the vitreous
    Deniz Dalkara
    Department of Chemical Engineering, The University of California at Berkeley, Berkeley, California 94720 3190, USA
    Mol Ther 17:2096-102. 2009
  2. pmc Changes in adeno-associated virus-mediated gene delivery in retinal degeneration
    Kathleen D Kolstad
    Department of Molecular and Cellular Biology and Helen Wills Neuroscience Institute, University of California at Berkeley, Berkeley, CA 94720 3190, USA
    Hum Gene Ther 21:571-8. 2010
  3. pmc AAV mediated GDNF secretion from retinal glia slows down retinal degeneration in a rat model of retinitis pigmentosa
    Deniz Dalkara
    Department of Molecular and Cell Biology and the Helen Wills Neuroscience Institute, University of California, Berkeley, California 94720 3190, USA
    Mol Ther 19:1602-8. 2011
  4. doi request reprint In vivo-directed evolution of a new adeno-associated virus for therapeutic outer retinal gene delivery from the vitreous
    Deniz Dalkara
    Helen Wills Neuroscience Institute, University of California, Berkeley, CA 94720 1462, USA
    Sci Transl Med 5:189ra76. 2013
  5. pmc Molecular evolution of adeno-associated virus for enhanced glial gene delivery
    James T Koerber
    Department of Chemical Engineering, Helen Wills Neuroscience Institute, The University of California, Berkeley, California 94720 1462, USA
    Mol Ther 17:2088-95. 2009
  6. pmc LiGluR restores visual responses in rodent models of inherited blindness
    Natalia Caporale
    Helen Wills Neuroscience Institute, University of California, Berkeley, California 94720 2020, USA
    Mol Ther 19:1212-9. 2011
  7. pmc Rapid optical control of nociception with an ion-channel photoswitch
    Alexandre Mourot
    Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California, USA
    Nat Methods 9:396-402. 2012

Collaborators

Detail Information

Publications7

  1. pmc Inner limiting membrane barriers to AAV-mediated retinal transduction from the vitreous
    Deniz Dalkara
    Department of Chemical Engineering, The University of California at Berkeley, Berkeley, California 94720 3190, USA
    Mol Ther 17:2096-102. 2009
    ..These findings may help avoid limitations, risks, and damage associated with subretinal injections currently necessary for clinical gene therapy...
  2. pmc Changes in adeno-associated virus-mediated gene delivery in retinal degeneration
    Kathleen D Kolstad
    Department of Molecular and Cellular Biology and Helen Wills Neuroscience Institute, University of California at Berkeley, Berkeley, CA 94720 3190, USA
    Hum Gene Ther 21:571-8. 2010
    ..Furthermore, these results indicate that gene delivery to the outer nuclear layer may be achieved by noninvasive intravitreal AAV administration in the diseased state...
  3. pmc AAV mediated GDNF secretion from retinal glia slows down retinal degeneration in a rat model of retinitis pigmentosa
    Deniz Dalkara
    Department of Molecular and Cell Biology and the Helen Wills Neuroscience Institute, University of California, Berkeley, California 94720 3190, USA
    Mol Ther 19:1602-8. 2011
    ..These findings also demonstrate for the first time that glia-mediated secretion of neurotrophins is a promising treatment that may be applicable to other neurodegenerative conditions...
  4. doi request reprint In vivo-directed evolution of a new adeno-associated virus for therapeutic outer retinal gene delivery from the vitreous
    Deniz Dalkara
    Helen Wills Neuroscience Institute, University of California, Berkeley, CA 94720 1462, USA
    Sci Transl Med 5:189ra76. 2013
    ..Furthermore, it enabled transduction of primate photoreceptors from the vitreous, expanding its therapeutic promise...
  5. pmc Molecular evolution of adeno-associated virus for enhanced glial gene delivery
    James T Koerber
    Department of Chemical Engineering, Helen Wills Neuroscience Institute, The University of California, Berkeley, California 94720 1462, USA
    Mol Ther 17:2088-95. 2009
    ....
  6. pmc LiGluR restores visual responses in rodent models of inherited blindness
    Natalia Caporale
    Helen Wills Neuroscience Institute, University of California, Berkeley, California 94720 2020, USA
    Mol Ther 19:1212-9. 2011
    ....
  7. pmc Rapid optical control of nociception with an ion-channel photoswitch
    Alexandre Mourot
    Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California, USA
    Nat Methods 9:396-402. 2012
    ..Because intracellular QAQ accumulation is a consequence of nociceptive ion-channel activity, QAQ-mediated photosensitization is a platform for understanding signaling mechanisms in acute and chronic pain...