S Dacic

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint Nodular amyloidoma and primary pulmonary lymphoma with amyloid production: a differential diagnostic problem
    S Dacic
    Department of Pathology, University of Pittsburgh Medical Center and Presbyterian University Hospital, Pennsylvania 15213, USA
    Mod Pathol 13:934-40. 2000
  2. ncbi request reprint Molecular pathogenesis of pulmonary carcinosarcoma as determined by microdissection-based allelotyping
    Sanja Dacic
    Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, Pennsylvania, USA
    Am J Surg Pathol 26:510-6. 2002
  3. ncbi request reprint Genotypic analysis of pulmonary Langerhans cell histiocytosis
    S Dacic
    Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh Medical Center, PA 15213, USA
    Hum Pathol 34:1345-9. 2003
  4. doi request reprint EGFR assays in lung cancer
    Sanja Dacic
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Adv Anat Pathol 15:241-7. 2008
  5. ncbi request reprint Transgenic mice overexpressing hepatocyte growth factor in the airways show increased susceptibility to lung cancer
    Laura P Stabile
    Department of Pharmacology, University of Pittsburgh Cancer Institute, PA 15261, USA
    Carcinogenesis 27:1547-55. 2006
  6. ncbi request reprint Significance of EGFR protein expression and gene amplification in non-small cell lung carcinoma
    Sanja Dacic
    Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, PA 15213, USA
    Am J Clin Pathol 125:860-5. 2006
  7. ncbi request reprint Molecular profiling of lung carcinoma: identifying clinically useful tumor markers for diagnosis and prognosis
    Sanja Dacic
    University of Pittsburgh Medical Center, Department of Pathology, PUH A610, Pittsburgh, PA 15213, USA
    Expert Rev Mol Diagn 7:77-86. 2007
  8. ncbi request reprint Microsatellite instability is uncommon in lymphoepithelioma-like carcinoma of the lung
    Sanja Dacic
    Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, PA 15213, USA
    Am J Clin Pathol 127:282-6. 2007
  9. ncbi request reprint Overexpression of Dicer in precursor lesions of lung adenocarcinoma
    Simion Chiosea
    Department of Pathology, University of Pittsburgh Medical Center Presbyterian, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Cancer Res 67:2345-50. 2007
  10. doi request reprint Pulmonary preneoplasia
    Sanja Dacic
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Arch Pathol Lab Med 132:1073-8. 2008

Collaborators

Detail Information

Publications31

  1. ncbi request reprint Nodular amyloidoma and primary pulmonary lymphoma with amyloid production: a differential diagnostic problem
    S Dacic
    Department of Pathology, University of Pittsburgh Medical Center and Presbyterian University Hospital, Pennsylvania 15213, USA
    Mod Pathol 13:934-40. 2000
    ..Amyloid tumors with a reactive lymphoplasmacytic infiltrate can be separated from low-grade malignant lymphomas utilizing both histologic and immunohistochemical features...
  2. ncbi request reprint Molecular pathogenesis of pulmonary carcinosarcoma as determined by microdissection-based allelotyping
    Sanja Dacic
    Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, Pennsylvania, USA
    Am J Surg Pathol 26:510-6. 2002
    ..The data support the efficacy of microdissection-based allelic fingerprinting to delineate the relationship between different morphologic components of a single neoplasm...
  3. ncbi request reprint Genotypic analysis of pulmonary Langerhans cell histiocytosis
    S Dacic
    Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh Medical Center, PA 15213, USA
    Hum Pathol 34:1345-9. 2003
    ....
  4. doi request reprint EGFR assays in lung cancer
    Sanja Dacic
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Adv Anat Pathol 15:241-7. 2008
    ..This review will address practical aspects of each of the currently proposed assays. Difficulties in standardization of these assays in a clinical practice will be discussed...
  5. ncbi request reprint Transgenic mice overexpressing hepatocyte growth factor in the airways show increased susceptibility to lung cancer
    Laura P Stabile
    Department of Pharmacology, University of Pittsburgh Cancer Institute, PA 15261, USA
    Carcinogenesis 27:1547-55. 2006
    ....
  6. ncbi request reprint Significance of EGFR protein expression and gene amplification in non-small cell lung carcinoma
    Sanja Dacic
    Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, PA 15213, USA
    Am J Clin Pathol 125:860-5. 2006
    ..EGFR protein expression was uncoupled from gene amplification in most cases, although good correlation occurred in a subset of SCCs...
  7. ncbi request reprint Molecular profiling of lung carcinoma: identifying clinically useful tumor markers for diagnosis and prognosis
    Sanja Dacic
    University of Pittsburgh Medical Center, Department of Pathology, PUH A610, Pittsburgh, PA 15213, USA
    Expert Rev Mol Diagn 7:77-86. 2007
    ..Although the impact of translating new technologies into clinical practice on survival has not been completely determined, they offer a new avenue of exciting novel approaches to early diagnosis of this deadly disease...
  8. ncbi request reprint Microsatellite instability is uncommon in lymphoepithelioma-like carcinoma of the lung
    Sanja Dacic
    Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, PA 15213, USA
    Am J Clin Pathol 127:282-6. 2007
    ..55). MSI is very uncommon in LELC, indicating that MSI is not an important event in carcinogenesis for this tumor subtype. The presence of LOH suggests a probable role of tumor suppressor genes in LELC carcinogenesis...
  9. ncbi request reprint Overexpression of Dicer in precursor lesions of lung adenocarcinoma
    Simion Chiosea
    Department of Pathology, University of Pittsburgh Medical Center Presbyterian, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Cancer Res 67:2345-50. 2007
    ..The status of the endogenous miR machinery in various histologic subtypes and stages of lung cancer may help to predict the toxicity of and susceptibility to future RNA interference-based therapy...
  10. doi request reprint Pulmonary preneoplasia
    Sanja Dacic
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Arch Pathol Lab Med 132:1073-8. 2008
    ..Recognition of these lesions is very important to prevent potential diagnostic mistakes that may result in inadequate patient management. Future molecular studies may provide clinically useful diagnostic and prognostic gene markers...
  11. ncbi request reprint Molecular alterations in atypical adenomatous hyperplasia occurring in benign and cancer-bearing lungs
    Joel F Gradowski
    Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Diagn Mol Pathol 16:87-90. 2007
    ..Therefore, AAH may represent a smoking induced low-grade neoplastic lesion that may be a precursor lesion of only a subset of invasive lung adenocarcinoma...
  12. ncbi request reprint Frequent inactivation of RAMP2, EFEMP1 and Dutt1 in lung cancer by promoter hypermethylation
    Wen Yue
    Department of Pharmacology, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Clin Cancer Res 13:4336-44. 2007
    ..The goal of this study is to identify novel genes frequently silenced by promoter hypermethylation in lung cancer...
  13. doi request reprint Gross cystic disease fluid protein-(GCDFP-15): expression in primary lung adenocarcinoma
    Joan M Striebel
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213 2582, USA
    Am J Surg Pathol 32:426-32. 2008
    ..This report details the first 11 cases of pulmonary adenocarcinoma to express GCDFP-15 and their distinctive morphology with frequent mucin production and coexpression of thyroid transcription factor-1 and synaptophysin...
  14. ncbi request reprint Patterns of allelic loss of synchronous adenocarcinomas of the lung
    Sanja Dacic
    Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, PA 15213, USA
    Am J Surg Pathol 29:897-902. 2005
    ..Our study showed that discordant and concordant genotypic profiles exist in morphologically similar synchronous ADC of the lung...
  15. ncbi request reprint Persistent fever in a lung transplant patient
    Diana N Ionescu
    Department of Pathology, Division of Anatomical Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Arch Pathol Lab Med 129:e153-4. 2005
  16. ncbi request reprint Small-cell neuroendocrine carcinoma displays unique profiles of tumor-suppressor gene loss in relationship to the primary site of formation
    Sanja Dacic
    Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, PA 15213, USA
    Hum Pathol 33:927-32. 2002
    ..These attributes can be effectively used for primary localization of metastatic SCNC, thereby assisting in the diagnosis and classification of this neoplasm...
  17. ncbi request reprint Idiopathic bronchiolocentric interstitial pneumonia
    Samuel A Yousem
    Department of Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, Pennsylvania 15213, USA
    Mod Pathol 15:1148-53. 2002
    ....
  18. ncbi request reprint Widespread molecular alterations present in stage I non-small cell lung carcinoma fail to predict tumor recurrence
    Fabien K Baksh
    Department of Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, Pennsylvania 15213, USA
    Mod Pathol 16:28-34. 2003
    ..The approach of investigating a panel of genes for alterations can be applied to any given tumor type, and provides information on patterns of mutations/LOH that can help us better understand the molecular biology of tumorigenesis...
  19. pmc Therapeutic targeting of human hepatocyte growth factor with a single neutralizing monoclonal antibody reduces lung tumorigenesis
    Laura P Stabile
    Department of Pharmacology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Mol Cancer Ther 7:1913-22. 2008
    ..These preclinical results show that blocking the HGF/c-Met interaction with a single monoclonal antibody delivered systemically can have profound inhibitory effects on development of lung tumors...
  20. ncbi request reprint Loss of heterozygosity patterns of sclerosing hemangioma of the lung and bronchioloalveolar carcinoma indicate a similar molecular pathogenesis
    Sanja Dacic
    Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, PA 15213, USA
    Arch Pathol Lab Med 128:880-4. 2004
    ..Most cases of SH are benign, but they can metastasize to the regional lymph nodes...
  21. ncbi request reprint Pulmonary lymphohistiocytic reactions temporally related to etanercept therapy
    Samuel A Yousem
    The Department of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213 2582, USA
    Mod Pathol 18:651-5. 2005
    ..The association with etanercept therapy and granulomatous reactions is discussed along with the differential diagnosis...
  22. ncbi request reprint Clonal selection of adenocarcinoma of the lung as determined by loss of heterozygosity
    Sanja Dacic
    Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, 200 Lothrop Street, PUH A610 2, Pittsburgh, PA 15213, USA
    Exp Mol Pathol 78:135-9. 2005
    ..A trend towards lower overall FAL in advanced stage tumors and in their metastases suggests that clonal selection may play a role in lung adenocarcinoma progression...
  23. ncbi request reprint Protein expression and gene amplification of epidermal growth factor receptor in thymomas
    Diana N Ionescu
    Division of Anatomic Pathology, Department of Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, Pennsylvania, USA
    Cancer 103:630-6. 2005
    ..There is little information in the literature regarding the biologic role of EGFR in thymomas that are characterized by variable clinical presentations, histologic heterogeneity, and unpredictable behavior...
  24. ncbi request reprint Immunohistochemical profile of cystosarcoma phyllodes of the breast: a study of 23 cases
    Sanja Dacic
    Department of Pathology, Magee Womens Hospital, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Breast J 8:376-81. 2002
    ..The positive immunostaining for bFGF, urokinase, Ki67, and p53 in stroma and epithelium of the majority of CP supports the existence of epithelial-stromal interactions and recognizes epithelium as an integral part of this tumor...
  25. doi request reprint Diagnostic importance of 9p21 homozygous deletion in malignant mesotheliomas
    Simion Chiosea
    Division of Anatomic Pathology, Department of Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, PA 15213, USA
    Mod Pathol 21:742-7. 2008
    ..A discrepancy between p16 protein expression and homozygous deletion suggests that other molecular mechanisms may play a role in p16 protein expression in mesothelial proliferations...
  26. ncbi request reprint Significance of a solitary perivascular mononuclear infiltrate in lung allograft recipients with mild acute cellular rejection
    Dong Won Kim
    Department of Pathology and Pulmonary Medicine, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, PA 15213, USA
    J Heart Lung Transplant 24:152-5. 2005
    ..We evaluated the significance of a solitary perivascular mononuclear infiltrate and its correlation with clinical outcome in lung allograft recipients...
  27. doi request reprint Array comparative genomic hybridization analysis of solid pseudopapillary neoplasms of the pancreas
    Chad R Rund
    Department of Pathology, Presbyterian Shadyside Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Mod Pathol 21:559-64. 2008
    ..Additional study and longer follow-up are needed to determine if these genetic abnormalities could help predict clinical behavior in these neoplasms...
  28. ncbi request reprint Downregulation of Dkk3 activates beta-catenin/TCF-4 signaling in lung cancer
    Wen Yue
    Department of Pharmacology
    Carcinogenesis 29:84-92. 2008
    ..These observations suggested that epigenetic inactivation of Dkk3 activates the Wnt/beta-catenin pathway, thereby promoting the growth of lung cancer cells...
  29. ncbi request reprint 2-Methoxyestradiol mediates the protective effects of estradiol in monocrotaline-induced pulmonary hypertension
    Stevan P Tofovic
    Center for Clinical Pharmacology, University of Pittsburgh School of Medicine, PA 15219, United States
    Vascul Pharmacol 45:358-67. 2006
    ..This study suggests that 2-methoxyestradiol (a major non-estrogenic metabolite of E2) may mediate the protective effects of estradiol in MCT-induced PH, and warrants further evaluation of 2ME for treatment of PH...
  30. ncbi request reprint Histologic classification of idiopathic chronic interstitial pneumonias
    Sanja Dacic
    Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, Pennsylvania, USA
    Am J Respir Cell Mol Biol 29:S5-9. 2003
  31. ncbi request reprint Immunohistological determination of ecto-nucleoside triphosphate diphosphohydrolase1 (NTPDase1) and 5'-nucleotidase in rat hippocampus reveals overlapping distribution
    Ivana Bjelobaba
    Department of Neurochemistry and Immunonology, Institute for Biological Research Sinisa Stankovic, Belgrade, Serbia
    Cell Mol Neurobiol 27:731-43. 2007
    ..Obtained results suggest that the broad overlapping distribution of these enzymes in neurons and glial cells reflects the functional importance of ectonucleotidase actions in the nervous system...