D Dabelea

Summary

Affiliation: University of Colorado Health Sciences Center
Country: USA

Publications

  1. doi request reprint The predisposition to obesity and diabetes in offspring of diabetic mothers
    Dana Dabelea
    Department of Preventive Medicine and Biometrics, University of Colorado School of Medicine, Denver, Colorado, USA
    Diabetes Care 30:S169-74. 2007
  2. ncbi request reprint Incidence of diabetes in youth in the United States
    Dana Dabelea
    University of Colorado Health Sciences Center, Department of Preventive Medicine and Biometrics, Denver, CO 80262, USA
    JAMA 297:2716-24. 2007
  3. pmc Reproductive history and hormonal birth control use are associated with coronary calcium progression in women with type 1 diabetes mellitus
    Janet K Snell-Bergeon
    Barbara Davis Center for Childhood Diabetes, University of Colorado at Denver and Health Sciences Center, Aurora, CO 80045, USA
    J Clin Endocrinol Metab 93:2142-8. 2008
  4. pmc Association of intrauterine exposure to maternal diabetes and obesity with type 2 diabetes in youth: the SEARCH Case-Control Study
    Dana Dabelea
    Department of Preventive Medicine and Biometrics, University of Colorado Denver, Denver, Colorado, USA
    Diabetes Care 31:1422-6. 2008
  5. ncbi request reprint Testing the accelerator hypothesis: body size, beta-cell function, and age at onset of type 1 (autoimmune) diabetes
    Dana Dabelea
    University of Colorado Health Sciences Center, Denver, Colorado, USA
    Diabetes Care 29:290-4. 2006
  6. ncbi request reprint Increasing prevalence of gestational diabetes mellitus (GDM) over time and by birth cohort: Kaiser Permanente of Colorado GDM Screening Program
    Dana Dabelea
    Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver, CO, USA
    Diabetes Care 28:579-84. 2005
  7. ncbi request reprint Intrauterine diabetic environment confers risks for type 2 diabetes mellitus and obesity in the offspring, in addition to genetic susceptibility
    D Dabelea
    Department of Diabetes, University of Medicine Timisoara, Romania
    J Pediatr Endocrinol Metab 14:1085-91. 2001
  8. ncbi request reprint Effect of type 1 diabetes on the gender difference in coronary artery calcification: a role for insulin resistance? The Coronary Artery Calcification in Type 1 Diabetes (CACTI) Study
    Dana Dabelea
    Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Diabetes 52:2833-9. 2003
  9. pmc Association of insulin sensitivity to lipids across the lifespan in people with Type 1 diabetes
    D M Maahs
    Barbara Davis Center for Childhood Diabetes, University of Colorado, Denver, CO, USA
    Diabet Med 28:148-55. 2011
  10. pmc The impact of neonatal breast-feeding on growth trajectories of youth exposed and unexposed to diabetes in utero: the EPOCH Study
    T L Crume
    Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Aurora, CO, USA
    Int J Obes (Lond) 36:529-34. 2012

Detail Information

Publications41

  1. doi request reprint The predisposition to obesity and diabetes in offspring of diabetic mothers
    Dana Dabelea
    Department of Preventive Medicine and Biometrics, University of Colorado School of Medicine, Denver, Colorado, USA
    Diabetes Care 30:S169-74. 2007
  2. ncbi request reprint Incidence of diabetes in youth in the United States
    Dana Dabelea
    University of Colorado Health Sciences Center, Department of Preventive Medicine and Biometrics, Denver, CO 80262, USA
    JAMA 297:2716-24. 2007
    ..Data on the incidence of diabetes mellitus (DM) among US youth according to racial/ethnic background and DM type are limited...
  3. pmc Reproductive history and hormonal birth control use are associated with coronary calcium progression in women with type 1 diabetes mellitus
    Janet K Snell-Bergeon
    Barbara Davis Center for Childhood Diabetes, University of Colorado at Denver and Health Sciences Center, Aurora, CO 80045, USA
    J Clin Endocrinol Metab 93:2142-8. 2008
    ..Coronary artery disease is increased in women with type 1 diabetes (T1D), compared with nondiabetic (Non-DM) women. Women with T1D have more menstrual dysfunction and are less likely to use hormonal birth control (BC) than Non-DM women...
  4. pmc Association of intrauterine exposure to maternal diabetes and obesity with type 2 diabetes in youth: the SEARCH Case-Control Study
    Dana Dabelea
    Department of Preventive Medicine and Biometrics, University of Colorado Denver, Denver, Colorado, USA
    Diabetes Care 31:1422-6. 2008
    ..These associations were explored in African-American, Hispanic, and non-Hispanic white youth participating in the SEARCH Case-Control Study...
  5. ncbi request reprint Testing the accelerator hypothesis: body size, beta-cell function, and age at onset of type 1 (autoimmune) diabetes
    Dana Dabelea
    University of Colorado Health Sciences Center, Denver, Colorado, USA
    Diabetes Care 29:290-4. 2006
    ..The "accelerator hypothesis" predicts that fatness is associated with an earlier age at onset of type 1 diabetes. We tested the hypothesis using data from the SEARCH for Diabetes in Youth study...
  6. ncbi request reprint Increasing prevalence of gestational diabetes mellitus (GDM) over time and by birth cohort: Kaiser Permanente of Colorado GDM Screening Program
    Dana Dabelea
    Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver, CO, USA
    Diabetes Care 28:579-84. 2005
    ..Given that the number of people with diabetes worldwide is expected to increase at record levels through 2030, we examined temporal trends in GDM among diverse ethnic groups...
  7. ncbi request reprint Intrauterine diabetic environment confers risks for type 2 diabetes mellitus and obesity in the offspring, in addition to genetic susceptibility
    D Dabelea
    Department of Diabetes, University of Medicine Timisoara, Romania
    J Pediatr Endocrinol Metab 14:1085-91. 2001
    ..This suggests that intensive glucose control during pregnancy might have extended beneficial effects, contributing to a decrease in the prevalence of childhood type 2 DM...
  8. ncbi request reprint Effect of type 1 diabetes on the gender difference in coronary artery calcification: a role for insulin resistance? The Coronary Artery Calcification in Type 1 Diabetes (CACTI) Study
    Dana Dabelea
    Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Diabetes 52:2833-9. 2003
    ..In conclusion, gender differences in insulin resistance-associated fat distribution may explain why type 1 diabetes increases coronary calcification in women relatively more than in men...
  9. pmc Association of insulin sensitivity to lipids across the lifespan in people with Type 1 diabetes
    D M Maahs
    Barbara Davis Center for Childhood Diabetes, University of Colorado, Denver, CO, USA
    Diabet Med 28:148-55. 2011
    ..Our objective was to explore the associations between insulin resistance (assessed by glucose infusion rate) and lipids in people with Type 1 diabetes and determine whether adiposity and/or average glycaemia influence these associations...
  10. pmc The impact of neonatal breast-feeding on growth trajectories of youth exposed and unexposed to diabetes in utero: the EPOCH Study
    T L Crume
    Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Aurora, CO, USA
    Int J Obes (Lond) 36:529-34. 2012
    ....
  11. doi request reprint Clinical evolution of beta cell function in youth with diabetes: the SEARCH for Diabetes in Youth study
    D Dabelea
    Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, 13001 East 17th Ave, Aurora, CO 80045, USA
    Diabetologia 55:3359-68. 2012
    ..This report describes the evolution and major determinants of beta cell function, assessed by fasting C-peptide (FCP), in the SEARCH for Diabetes in Youth study...
  12. pmc Early-life predictors of higher body mass index in healthy children
    Molly M Lamb
    Department of Epidemiology, University of Colorado Denver, Aurora, 80045, USA
    Ann Nutr Metab 56:16-22. 2010
    ..Prospective analyses may better define the pathways between early life factors and greater childhood body mass index (BMI), a measure of obesity...
  13. pmc Inflammatory markers are increased in youth with type 1 diabetes: the SEARCH Case-Control study
    Janet K Snell-Bergeon
    Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, P O Box 6511, Mail Stop A 140, Aurora, Colorado 80045, USA
    J Clin Endocrinol Metab 95:2868-76. 2010
    ..Increased inflammation may contribute to type 1 diabetes (T1D) complications...
  14. pmc Association of exposure to diabetes in utero with adiposity and fat distribution in a multiethnic population of youth: the Exploring Perinatal Outcomes among Children (EPOCH) Study
    T L Crume
    Department of Epidemiology, University of Colorado Denver, Aurora, 80045, USA
    Diabetologia 54:87-92. 2011
    ..To evaluate whether exposure to maternal gestational diabetes (GDM) is associated with adiposity and fat distribution in a multiethnic population of children...
  15. pmc Association of glycaemia with lipids in adults with type 1 diabetes: modification by dyslipidaemia medication
    D M Maahs
    Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Mail Stop A140, PO Box 6511, Aurora, CO 80045, USA
    Diabetologia 53:2518-25. 2010
    ..The hypothesis of this study was that change in HbA(1c) over 6 years would be associated with change in fasting lipids in adults with type 1 diabetes...
  16. doi request reprint Development, validation and use of an insulin sensitivity score in youths with diabetes: the SEARCH for Diabetes in Youth study
    D Dabelea
    Department of Epidemiology, University of Colorado Denver, Aurora, 80045, USA
    Diabetologia 54:78-86. 2011
    ..Our goal was to develop and validate an insulin sensitivity (IS) score using the euglycaemic-hyperinsulinaemic clamp in a subset (nā€‰=ā€‰85) of 12- to 19-year-old youths with diabetes participating in the SEARCH study in Colorado, USA...
  17. pmc Height growth velocity, islet autoimmunity and type 1 diabetes development: the Diabetes Autoimmunity Study in the Young
    M M Lamb
    University of Colorado Denver, Aurora, 80045, USA
    Diabetologia 52:2064-71. 2009
    ..We analysed height, weight, BMI and velocities of growth in height, weight and BMI, for association with development of islet autoimmunity (IA) and type 1 diabetes...
  18. pmc Cardiovascular risk factors in children exposed to maternal diabetes in utero
    N A West
    Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, 13001 East 17th Avenue, Campus Box B 119, Aurora, CO 80045, USA
    Diabetologia 54:504-7. 2011
    ....
  19. ncbi request reprint The epidemiology of childhood-onset type 1 diabetes mellitus in Romania. ONROCAD Study Group. National Romanian Organisation for the Care of Diabetic Children and Adolescents
    V Serban
    Department of Diabetes, University for Medicine and Pharmacy, Timisoara, Romania
    J Pediatr Endocrinol Metab 14:535-41. 2001
    ..Significant, but unexplained, geographical variation exists within Romania. Searches for factors to explain this heterogeneity may provide clues to the etiology of childhood-onset type 1 DM...
  20. ncbi request reprint Progression of coronary artery calcification in type 1 diabetes: the importance of glycemic control
    Janet K Snell-Bergeon
    Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Diabetes Care 26:2923-8. 2003
    ....
  21. ncbi request reprint Evaluating changes in coronary artery calcium: an analytic method that accounts for interscan variability
    John E Hokanson
    Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, 4200 E Ninth Ave, B 119, Denver, CO 80262, USA
    AJR Am J Roentgenol 182:1327-32. 2004
    ..The transformation that stabilized the variation in calcium volume scores was applied to progression of calcium volume scores in 109 subjects with diabetes...
  22. ncbi request reprint Hypertension prevalence, awareness, treatment, and control in an adult type 1 diabetes population and a comparable general population
    David M Maahs
    Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, 4200 East 9th Ave, Denver, CO 80262, USA
    Diabetes Care 28:301-6. 2005
    ..To compare the prevalence, awareness, treatment, and control of hypertension in a population-representative sample of adults with type 1 diabetes and comparable nondiabetic control subjects...
  23. pmc Trends in high-risk HLA susceptibility genes among Colorado youth with type 1 diabetes
    Kendra Vehik
    University of Colorado Denver, School of Medicine, Denver, Colorado, USA
    Diabetes Care 31:1392-6. 2008
    ....
  24. ncbi request reprint Low plasma adiponectin levels predict progression of coronary artery calcification
    David M Maahs
    Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, 4200 E 9th Ave, Denver, CO 80262, USA
    Circulation 111:747-53. 2005
    ..However, it is not known whether low adiponectin levels predict development of atherosclerosis independently of other cardiovascular risk factors...
  25. ncbi request reprint Increasing incidence of type 1 diabetes in 0- to 17-year-old Colorado youth
    Kendra Vehik
    University of Colorado School of Medicine, Denver, Colorado, USA
    Diabetes Care 30:503-9. 2007
    ....
  26. pmc The association between adiponectin/leptin ratio and diabetes type: the SEARCH for Diabetes in Youth Study
    David M Maahs
    Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Denver, CO, USA
    J Pediatr 155:133-5, 135.e1. 2009
    ..Although adiponectin/leptin ratio is associated with diabetes type in youth, it is due to differences in adiponectin, but not leptin levels...
  27. ncbi request reprint Determinants of serum adiponectin in persons with and without type 1 diabetes
    David M Maahs
    Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, Aurora, CO 80045, USA
    Am J Epidemiol 166:731-40. 2007
    ..Although some of the difference can be explained, further study is needed to better understand the relation between elevated adiponectin levels and patient outcomes, including coronary heart disease...
  28. pmc Age at menarche and first pregnancy among psychosocially at-risk adolescents
    Jessica Dunbar
    Department of Preventive Medicine and Biometrics, University of Colorado, Denver, Health Sciences Center, Denver, CO 80045, USA
    Am J Public Health 98:1822-4. 2008
    ..Pregnancy prevention interventions to delay coitarche should also include reproductive education and contraception...
  29. doi request reprint Birth weight [corrected] and elevated albumin to creatinine ratio in youth with diabetes: the SEARCH for Diabetes in Youth study
    David M Maahs
    Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, Denver, CO, USA
    Pediatr Nephrol 23:2255-60. 2008
    ..00-2.69, p = 0.0503] for low BWT compared with reference BWT. Whereas low BWT may be a factor in kidney disease, little evidence was found of a relationship between low BWT and elevated ACR in this study population of youth with diabetes...
  30. ncbi request reprint Higher prevalence of elevated albumin excretion in youth with type 2 than type 1 diabetes: the SEARCH for Diabetes in Youth study
    David M Maahs
    Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, P O Box 6511, Mail Stop A140, Aurora, CO 80045, USA
    Diabetes Care 30:2593-8. 2007
    ....
  31. pmc Association testing of TCF7L2 polymorphisms with type 2 diabetes in multi-ethnic youth
    D Dabelea
    Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, 13001 17th Place, Aurora, CO 80045, USA
    Diabetologia 54:535-9. 2011
    ..Using a case-control design, we examined whether the reported variants [rs12255372 (T/G) and rs7903146 (T/C)] are associated with type 2 diabetes in SEARCH for Diabetes in Youth study participants...
  32. doi request reprint Determinants of adiponectin levels in young people with Type 1 diabetes
    M M Barnes
    Department of Preventive Medicine and Biometrics, University of Colorado School of Medicine, Denver, CO 80262, USA
    Diabet Med 25:365-9. 2008
    ..To determine whether adiponectin levels are higher in youth with Type 1 diabetes than in non-diabetic controls, and explore potential determinants for this difference...
  33. ncbi request reprint Measurement of abdominal fat by CT compared to waist circumference and BMI in explaining the presence of coronary calcium
    J K Snell-Bergeon
    Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Int J Obes Relat Metab Disord 28:1594-9. 2004
    ..To evaluate the association between standard and computed tomography (CT)-based measures of obesity and subclinical atherosclerosis, defined as coronary artery calcium (CAC) by Electron Beam Computed Tomography (EBCT)...
  34. ncbi request reprint Epidemiology of type 1 Diabetes Mellitus
    Marian Rewers
    Barbara Davis Center for Childhood Diabetes, University of Colorado, Health Sciences Center, Denver, USA
    Adv Exp Med Biol 552:219-46. 2004
    ..Current research effort is focused on identification of the genetic and environmental determinants of this process and the ways they interact...
  35. pmc Diabetes in Navajo youth: prevalence, incidence, and clinical characteristics: the SEARCH for Diabetes in Youth Study
    Dana Dabelea
    Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Denver, Colorado, USA
    Diabetes Care 32:S141-7. 2009
    ..To estimate the prevalence and incidence of diabetes, clinical characteristics, and risk factors for chronic complications among Navajo youth, using data collected by the SEARCH for Diabetes in Youth Study (SEARCH study)...
  36. pmc Lipid and lipoprotein profiles in youth with and without type 1 diabetes: the SEARCH for Diabetes in Youth case-control study
    John Guy
    Department of Epidemiology, Colorado School of Public Health, University of Colorado, Denver, Colorado, USA
    Diabetes Care 32:416-20. 2009
    ....
  37. doi request reprint Presence of diabetic ketoacidosis at diagnosis of diabetes mellitus in youth: the Search for Diabetes in Youth Study
    Arleta Rewers
    Department of Pediatrics, University of Colorado at Denver and Health Sciences Center, Denver, Colorado, USA
    Pediatrics 121:e1258-66. 2008
    ..The purpose of this work was to determine the prevalence and predictors of diabetic ketoacidosis at the diagnosis of diabetes in a large sample of youth from the US population...
  38. pmc Measures of arterial stiffness in youth with type 1 and type 2 diabetes: the SEARCH for diabetes in youth study
    R Paul Wadwa
    Barbara Davis Center for Childhood Diabetes, University of Colorado School ofMedicine, Aurora, Colorado, USA
    Diabetes Care 33:881-6. 2010
    ..We identified factors associated with arterial stiffness in youth with diabetes and assessed the effects of these factors on the relationship between arterial stiffness and diabetes type (type 1 vs. type 2)...
  39. pmc Type 2 diabetes-associated missense polymorphisms KCNJ11 E23K and ABCC8 A1369S influence progression to diabetes and response to interventions in the Diabetes Prevention Program
    Jose C Florez
    Diabetes Prevention Program Coordinating Center, Biostatistics Center, George Washington University, 6110 Executive Blvd, Suite 750, Rockville, MD 20852, USA
    Diabetes 56:531-6. 2007
    ..We further hypothesize that the diabetes-preventive effect of metformin may interact with the impact of these variants on insulin regulation...
  40. doi request reprint Health-related quality of life of children and adolescents with type 1 or type 2 diabetes mellitus: SEARCH for Diabetes in Youth Study
    Michelle J Naughton
    Department of Social Sciences and Health Policy, Division of Public Health Sciences, Wake Forest University School of Medicine, 2000 W First St, Winston Salem, NC 27104, USA
    Arch Pediatr Adolesc Med 162:649-57. 2008
    ..To examine the associations between demographic and diabetes management variables and the health-related quality of life (HRQOL) of youths with type 1 or type 2 diabetes mellitus (DM)...
  41. ncbi request reprint Breast-feeding and type 2 diabetes in the youth of three ethnic groups: the SEARCh for diabetes in youth case-control study
    Elizabeth J Mayer-Davis
    Center for Research in Nutrition and Health Disparities and Epidemiology and Biostatistics, University of South Carolina, Columbia, South Carolina 29208, USA
    Diabetes Care 31:470-5. 2008
    ..To evaluate the hypothesis that breast-feeding is associated with reduced type 2 diabetes among African-American, Hispanic, and non-Hispanic white youth, mediated in part by current weight status...

Research Grants11

  1. Exploring the Fuel-Mediated Programming of Neonatal Growth
    Dana Dabelea; Fiscal Year: 2010
    ....
  2. Exploring the Fetal Origins Hypothesis in Diverse Youth
    Dana Dabelea; Fiscal Year: 2009
    ..Such studies could ultimately lead to the development of strategies for early life prevention of future chronic disorders. ..
  3. SEARCH for Diabetes in Youth 2: Colorado Center
    Dana Dabelea; Fiscal Year: 2007
    ..The estimated total population under surveillance at the Colorado SEARCHsite is -1.4million youth age < 20 years, which makes our center the largest current SEARCHsite. ..
  4. Sub Clinical Cardiovascular Disease in Youth (SEARCH CVD)
    Dana Dabelea; Fiscal Year: 2010
    ..This study will advance our understanding of the natural history of early CVD in youth, and will provide insights into the mechanisms from which strategies to prevent or limit vascular disease in individuals with T1D can be developed. ..