Research Topics
Species | D DabeleaSummaryAffiliation: University of Colorado Health Sciences Center Country: USA Publications
Research Grants
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Detail Information
Publications
The predisposition to obesity and diabetes in offspring of diabetic mothersDana Dabelea
Department of Preventive Medicine and Biometrics, University of Colorado School of Medicine, Denver, Colorado, USA
Diabetes Care 30:S169-74. 2007- Incidence of diabetes in youth in the United StatesDana Dabelea
University of Colorado Health Sciences Center, Department of Preventive Medicine and Biometrics, Denver, CO 80262, USA
JAMA 297:2716-24. 2007..Data on the incidence of diabetes mellitus (DM) among US youth according to racial/ethnic background and DM type are limited... - Reproductive history and hormonal birth control use are associated with coronary calcium progression in women with type 1 diabetes mellitusJanet K Snell-Bergeon
Barbara Davis Center for Childhood Diabetes, University of Colorado at Denver and Health Sciences Center, Aurora, CO 80045, USA
J Clin Endocrinol Metab 93:2142-8. 2008..Coronary artery disease is increased in women with type 1 diabetes (T1D), compared with nondiabetic (Non-DM) women. Women with T1D have more menstrual dysfunction and are less likely to use hormonal birth control (BC) than Non-DM women... - Association of intrauterine exposure to maternal diabetes and obesity with type 2 diabetes in youth: the SEARCH Case-Control StudyDana Dabelea
Department of Preventive Medicine and Biometrics, University of Colorado Denver, Denver, Colorado, USA
Diabetes Care 31:1422-6. 2008..These associations were explored in African-American, Hispanic, and non-Hispanic white youth participating in the SEARCH Case-Control Study... - Testing the accelerator hypothesis: body size, beta-cell function, and age at onset of type 1 (autoimmune) diabetesDana Dabelea
University of Colorado Health Sciences Center, Denver, Colorado, USA
Diabetes Care 29:290-4. 2006..The "accelerator hypothesis" predicts that fatness is associated with an earlier age at onset of type 1 diabetes. We tested the hypothesis using data from the SEARCH for Diabetes in Youth study... - Increasing prevalence of gestational diabetes mellitus (GDM) over time and by birth cohort: Kaiser Permanente of Colorado GDM Screening ProgramDana Dabelea
Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver, CO, USA
Diabetes Care 28:579-84. 2005..Given that the number of people with diabetes worldwide is expected to increase at record levels through 2030, we examined temporal trends in GDM among diverse ethnic groups... - Intrauterine diabetic environment confers risks for type 2 diabetes mellitus and obesity in the offspring, in addition to genetic susceptibilityD Dabelea
Department of Diabetes, University of Medicine Timisoara, Romania
J Pediatr Endocrinol Metab 14:1085-91. 2001..This suggests that intensive glucose control during pregnancy might have extended beneficial effects, contributing to a decrease in the prevalence of childhood type 2 DM... - Effect of type 1 diabetes on the gender difference in coronary artery calcification: a role for insulin resistance? The Coronary Artery Calcification in Type 1 Diabetes (CACTI) StudyDana Dabelea
Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
Diabetes 52:2833-9. 2003..In conclusion, gender differences in insulin resistance-associated fat distribution may explain why type 1 diabetes increases coronary calcification in women relatively more than in men... - Association of insulin sensitivity to lipids across the lifespan in people with Type 1 diabetesD M Maahs
Barbara Davis Center for Childhood Diabetes, University of Colorado, Denver, CO, USA
Diabet Med 28:148-55. 2011..Our objective was to explore the associations between insulin resistance (assessed by glucose infusion rate) and lipids in people with Type 1 diabetes and determine whether adiposity and/or average glycaemia influence these associations... - The impact of neonatal breast-feeding on growth trajectories of youth exposed and unexposed to diabetes in utero: the EPOCH StudyT L Crume
Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Aurora, CO, USA
Int J Obes (Lond) 36:529-34. 2012.... - Early-life predictors of higher body mass index in healthy childrenMolly M Lamb
Department of Epidemiology, University of Colorado Denver, Aurora, 80045, USA
Ann Nutr Metab 56:16-22. 2010..Prospective analyses may better define the pathways between early life factors and greater childhood body mass index (BMI), a measure of obesity... - Inflammatory markers are increased in youth with type 1 diabetes: the SEARCH Case-Control studyJanet K Snell-Bergeon
Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, P O Box 6511, Mail Stop A 140, Aurora, Colorado 80045, USA
J Clin Endocrinol Metab 95:2868-76. 2010..Increased inflammation may contribute to type 1 diabetes (T1D) complications... - Association of exposure to diabetes in utero with adiposity and fat distribution in a multiethnic population of youth: the Exploring Perinatal Outcomes among Children (EPOCH) StudyT L Crume
Department of Epidemiology, University of Colorado Denver, Aurora, 80045, USA
Diabetologia 54:87-92. 2011..To evaluate whether exposure to maternal gestational diabetes (GDM) is associated with adiposity and fat distribution in a multiethnic population of children... - Association of glycaemia with lipids in adults with type 1 diabetes: modification by dyslipidaemia medicationD M Maahs
Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Mail Stop A140, PO Box 6511, Aurora, CO 80045, USA
Diabetologia 53:2518-25. 2010..The hypothesis of this study was that change in HbA(1c) over 6 years would be associated with change in fasting lipids in adults with type 1 diabetes... - Development, validation and use of an insulin sensitivity score in youths with diabetes: the SEARCH for Diabetes in Youth studyD Dabelea
Department of Epidemiology, University of Colorado Denver, Aurora, 80045, USA
Diabetologia 54:78-86. 2011..Our goal was to develop and validate an insulin sensitivity (IS) score using the euglycaemic-hyperinsulinaemic clamp in a subset (n = 85) of 12- to 19-year-old youths with diabetes participating in the SEARCH study in Colorado, USA... - Clinical evolution of beta cell function in youth with diabetes: the SEARCH for Diabetes in Youth studyD Dabelea
Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, 13001 East 17th Ave, Box B119, Aurora, CO, 80045, USA
Diabetologia 55:3359-68. 2012..This report describes the evolution and major determinants of beta cell function, assessed by fasting C-peptide (FCP), in the SEARCH for Diabetes in Youth study... - Height growth velocity, islet autoimmunity and type 1 diabetes development: the Diabetes Autoimmunity Study in the YoungM M Lamb
University of Colorado Denver, Aurora, 80045, USA
Diabetologia 52:2064-71. 2009..We analysed height, weight, BMI and velocities of growth in height, weight and BMI, for association with development of islet autoimmunity (IA) and type 1 diabetes... - Cardiovascular risk factors in children exposed to maternal diabetes in uteroN A West
Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, 13001 East 17th Avenue, Campus Box B 119, Aurora, CO 80045, USA
Diabetologia 54:504-7. 2011.... - The epidemiology of childhood-onset type 1 diabetes mellitus in Romania. ONROCAD Study Group. National Romanian Organisation for the Care of Diabetic Children and AdolescentsV Serban
Department of Diabetes, University for Medicine and Pharmacy, Timisoara, Romania
J Pediatr Endocrinol Metab 14:535-41. 2001..Significant, but unexplained, geographical variation exists within Romania. Searches for factors to explain this heterogeneity may provide clues to the etiology of childhood-onset type 1 DM... - Progression of coronary artery calcification in type 1 diabetes: the importance of glycemic controlJanet K Snell-Bergeon
Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
Diabetes Care 26:2923-8. 2003.... - Evaluating changes in coronary artery calcium: an analytic method that accounts for interscan variabilityJohn E Hokanson
Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, 4200 E Ninth Ave, B 119, Denver, CO 80262, USA
AJR Am J Roentgenol 182:1327-32. 2004..The transformation that stabilized the variation in calcium volume scores was applied to progression of calcium volume scores in 109 subjects with diabetes... - Hypertension prevalence, awareness, treatment, and control in an adult type 1 diabetes population and a comparable general populationDavid M Maahs
Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, 4200 East 9th Ave, Denver, CO 80262, USA
Diabetes Care 28:301-6. 2005..To compare the prevalence, awareness, treatment, and control of hypertension in a population-representative sample of adults with type 1 diabetes and comparable nondiabetic control subjects... - Trends in high-risk HLA susceptibility genes among Colorado youth with type 1 diabetesKendra Vehik
University of Colorado Denver, School of Medicine, Denver, Colorado, USA
Diabetes Care 31:1392-6. 2008.... - Low plasma adiponectin levels predict progression of coronary artery calcificationDavid M Maahs
Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, 4200 E 9th Ave, Denver, CO 80262, USA
Circulation 111:747-53. 2005..However, it is not known whether low adiponectin levels predict development of atherosclerosis independently of other cardiovascular risk factors... - Increasing incidence of type 1 diabetes in 0- to 17-year-old Colorado youthKendra Vehik
University of Colorado School of Medicine, Denver, Colorado, USA
Diabetes Care 30:503-9. 2007.... - The association between adiponectin/leptin ratio and diabetes type: the SEARCH for Diabetes in Youth StudyDavid M Maahs
Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Denver, CO, USA
J Pediatr 155:133-5, 135.e1. 2009..Although adiponectin/leptin ratio is associated with diabetes type in youth, it is due to differences in adiponectin, but not leptin levels... - Determinants of serum adiponectin in persons with and without type 1 diabetesDavid M Maahs
Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, Aurora, CO 80045, USA
Am J Epidemiol 166:731-40. 2007..Although some of the difference can be explained, further study is needed to better understand the relation between elevated adiponectin levels and patient outcomes, including coronary heart disease... - Age at menarche and first pregnancy among psychosocially at-risk adolescentsJessica Dunbar
Department of Preventive Medicine and Biometrics, University of Colorado, Denver, Health Sciences Center, Denver, CO 80045, USA
Am J Public Health 98:1822-4. 2008..Pregnancy prevention interventions to delay coitarche should also include reproductive education and contraception... - Birth weight [corrected] and elevated albumin to creatinine ratio in youth with diabetes: the SEARCH for Diabetes in Youth studyDavid M Maahs
Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, Denver, CO, USA
Pediatr Nephrol 23:2255-60. 2008..00-2.69, p = 0.0503] for low BWT compared with reference BWT. Whereas low BWT may be a factor in kidney disease, little evidence was found of a relationship between low BWT and elevated ACR in this study population of youth with diabetes... - Higher prevalence of elevated albumin excretion in youth with type 2 than type 1 diabetes: the SEARCH for Diabetes in Youth studyDavid M Maahs
Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, P O Box 6511, Mail Stop A140, Aurora, CO 80045, USA
Diabetes Care 30:2593-8. 2007.... - Association testing of TCF7L2 polymorphisms with type 2 diabetes in multi-ethnic youthD Dabelea
Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, 13001 17th Place, Aurora, CO 80045, USA
Diabetologia 54:535-9. 2011..Using a case-control design, we examined whether the reported variants [rs12255372 (T/G) and rs7903146 (T/C)] are associated with type 2 diabetes in SEARCH for Diabetes in Youth study participants... - Determinants of adiponectin levels in young people with Type 1 diabetesM M Barnes
Department of Preventive Medicine and Biometrics, University of Colorado School of Medicine, Denver, CO 80262, USA
Diabet Med 25:365-9. 2008..To determine whether adiponectin levels are higher in youth with Type 1 diabetes than in non-diabetic controls, and explore potential determinants for this difference... - Measurement of abdominal fat by CT compared to waist circumference and BMI in explaining the presence of coronary calciumJ K Snell-Bergeon
Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
Int J Obes Relat Metab Disord 28:1594-9. 2004..To evaluate the association between standard and computed tomography (CT)-based measures of obesity and subclinical atherosclerosis, defined as coronary artery calcium (CAC) by Electron Beam Computed Tomography (EBCT)... - Epidemiology of type 1 Diabetes MellitusMarian Rewers
Barbara Davis Center for Childhood Diabetes, University of Colorado, Health Sciences Center, Denver, USA
Adv Exp Med Biol 552:219-46. 2004..Current research effort is focused on identification of the genetic and environmental determinants of this process and the ways they interact... - Diabetes in Navajo youth: prevalence, incidence, and clinical characteristics: the SEARCH for Diabetes in Youth StudyDana Dabelea
Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Denver, Colorado, USA
Diabetes Care 32:S141-7. 2009..To estimate the prevalence and incidence of diabetes, clinical characteristics, and risk factors for chronic complications among Navajo youth, using data collected by the SEARCH for Diabetes in Youth Study (SEARCH study)... - Lipid and lipoprotein profiles in youth with and without type 1 diabetes: the SEARCH for Diabetes in Youth case-control studyJohn Guy
Department of Epidemiology, Colorado School of Public Health, University of Colorado, Denver, Colorado, USA
Diabetes Care 32:416-20. 2009.... - Presence of diabetic ketoacidosis at diagnosis of diabetes mellitus in youth: the Search for Diabetes in Youth StudyArleta Rewers
Department of Pediatrics, University of Colorado at Denver and Health Sciences Center, Denver, Colorado, USA
Pediatrics 121:e1258-66. 2008..The purpose of this work was to determine the prevalence and predictors of diabetic ketoacidosis at the diagnosis of diabetes in a large sample of youth from the US population... - Measures of arterial stiffness in youth with type 1 and type 2 diabetes: the SEARCH for diabetes in youth studyR Paul Wadwa
Barbara Davis Center for Childhood Diabetes, University of Colorado School ofMedicine, Aurora, Colorado, USA
Diabetes Care 33:881-6. 2010..We identified factors associated with arterial stiffness in youth with diabetes and assessed the effects of these factors on the relationship between arterial stiffness and diabetes type (type 1 vs. type 2)... - Type 2 diabetes-associated missense polymorphisms KCNJ11 E23K and ABCC8 A1369S influence progression to diabetes and response to interventions in the Diabetes Prevention ProgramJose C Florez
Diabetes Prevention Program Coordinating Center, Biostatistics Center, George Washington University, 6110 Executive Blvd, Suite 750, Rockville, MD 20852, USA
Diabetes 56:531-6. 2007..We further hypothesize that the diabetes-preventive effect of metformin may interact with the impact of these variants on insulin regulation... - Health-related quality of life of children and adolescents with type 1 or type 2 diabetes mellitus: SEARCH for Diabetes in Youth StudyMichelle J Naughton
Department of Social Sciences and Health Policy, Division of Public Health Sciences, Wake Forest University School of Medicine, 2000 W First St, Winston Salem, NC 27104, USA
Arch Pediatr Adolesc Med 162:649-57. 2008..To examine the associations between demographic and diabetes management variables and the health-related quality of life (HRQOL) of youths with type 1 or type 2 diabetes mellitus (DM)... - Breast-feeding and type 2 diabetes in the youth of three ethnic groups: the SEARCh for diabetes in youth case-control studyElizabeth J Mayer-Davis
Center for Research in Nutrition and Health Disparities and Epidemiology and Biostatistics, University of South Carolina, Columbia, South Carolina 29208, USA
Diabetes Care 31:470-5. 2008..To evaluate the hypothesis that breast-feeding is associated with reduced type 2 diabetes among African-American, Hispanic, and non-Hispanic white youth, mediated in part by current weight status...
Research Grants
- Exploring the Fuel-Mediated Programming of Neonatal GrowthDana Dabelea; Fiscal Year: 2010....
- Exploring the Fetal Origins Hypothesis in Diverse YouthDana Dabelea; Fiscal Year: 2009..Such studies could ultimately lead to the development of strategies for early life prevention of future chronic disorders. ..
- SEARCH for Diabetes in Youth 2: Colorado CenterDana Dabelea; Fiscal Year: 2007..The estimated total population under surveillance at the Colorado SEARCHsite is -1.4million youth age < 20 years, which makes our center the largest current SEARCHsite. ..
- Sub Clinical Cardiovascular Disease in Youth (SEARCH CVD)Dana Dabelea; Fiscal Year: 2010..This study will advance our understanding of the natural history of early CVD in youth, and will provide insights into the mechanisms from which strategies to prevent or limit vascular disease in individuals with T1D can be developed. ..